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1 4c was potent as the prototypical quinolone, nalidixic acid (1), with an IC50 value of 58.3 microgram
2 molar tooth appearance on anaerobic colistin nalidixic acid (CNA) agar which likely facilitated its d
3 iated to determine whether Columbia colistin-nalidixic acid (CNA) agar would be an equally sensitive,
4 nto blood (blood agar plate [BAP]), colistin-nalidixic acid (CNA), and MacConkey agars in 5% CO2 for
5 sed to rifampicin (transcription inhibitor), nalidixic acid (gyrase inhibitor), or A22 (MreB-cytoskel
6 culture on MacConkey agar supplemented with nalidixic acid (MACnal) and compared to overnight broth
7 bind not only quinolone antibiotics such as nalidixic acid (NA) and flumequine (FLU), but also salic
8 R), sarafloxacin (SAR), oxolinic acid (OXO), nalidixic acid (NAL) and flumequine (FLU) were separated
10 ous Fenton-like reactions for the removal of nalidixic acid (NAL), a recalcitrant quinolone antibacte
11 susceptibility, the proportion resistant to nalidixic acid (NAL-R) increased from 2008 to 2012 (Typh
12 Typhi [MDRST]); 758 (38%) were resistant to nalidixic acid (nalidixic acid-resistant S. Typhi [NARST
15 were 2.2 [ampicillin (AMP), p=0.017] to 23 [nalidixic acid (NX), p<0.001] times more likely to harbo
16 ty of Todd-Hewitt medium with gentamicin and nalidixic acid (SBM) with our current method of direct p
18 occus isolates grown on blood agar, colistin-nalidixic acid agar (CNA), and mannitol salt agar (MSA);
20 eep blood agar, chocolate agar, and colistin-nalidixic acid agar after 24 to 48 h of incubation at 35
21 d sharply increasing trends in resistance to nalidixic acid and ciprofloxacin for both ST and SPA.
24 xacin), and three quinolones (oxolinic acid, nalidixic acid and flumequine) in eggs is presented.
25 e induced in a LexA-dependent manner by both nalidixic acid and mitomycin C, identifying these as mem
27 emiselective blood agar medium incorporating nalidixic acid and sulfamethazine (NAS) is described.
28 ays a role in modulating the SOS response to nalidixic acid and that the response is more complex tha
30 antially reduced for SOS induction following nalidixic acid but not UV treatment, and which were also
32 Disk diffusion using these antibiotics and nalidixic acid failed to detect some low-level-resistant
34 A subset of SOS genes lost their response to nalidixic acid in the dnaQ mutant strain, while two test
35 usceptible to ciprofloxacin but resistant to nalidixic acid in vitro, a pattern associated with fluor
37 howed increased survival on media containing nalidixic acid or rifampicin, but did not have an increa
40 itt broth supplemented with 10 micrograms of nalidixic acid per ml and 15 micrograms of colistin per
43 es of spontaneous mutation to rifampicin and nalidixic acid resistance in one medium and one fast str
48 perturb a GyrA-GyrA dimer interface allowed nalidixic acid to fragment chromosomes and kill cells in
49 A disk diffusion breakpoint was derived for nalidixic acid to serve as a surrogate marker for gyrase
51 specifically deficient in SOS induction upon nalidixic acid treatment by using a dinD::lacZ reporter
53 chromosome replication was blocked by either nalidixic acid treatment or thymine starvation, the tran
54 hed greater than 10-fold in the medium after nalidixic acid treatment, suggesting these were released
60 rom the production of an antibacterial drug (nalidixic acid) was investigated employing a membrane bi
61 antibiotics (vancomycin, amphotericin B, and nalidixic acid), and the efficacy of solid (Herrold's eg
62 r characteristics, (ii) the concentration of nalidixic acid, (iii) the 48 organics identified in the
64 on-inducible lexA mutant hypersusceptible to nalidixic acid, a property restricted to fluoroquinolone
67 ant resistant to the prototype of quinolone, nalidixic acid, and created complexes on DNA detected by
68 eased spontaneous resistance to rifampin and nalidixic acid, and MMC/uvrD double mutants exhibited hi
70 ion elongation was blocked by hydroxyurea or nalidixic acid, arrested cells contained one partially r
72 r alkaline phosphatase, and was resistant to nalidixic acid, cephalothin, and trimethoprim-sulfametho
73 , the MICs and inhibition zone diameters for nalidixic acid, ciprofloxacin, levofloxacin, and ofloxac
76 were selected on the basis of resistance to nalidixic acid, representing a variety of the most preva
77 eptibility to various antibiotics, including nalidixic acid, rifampin, novobiocin, and chloramphenico
78 re resistant to ampicillin, chloramphenicol, nalidixic acid, streptomycin, sulfisoxazole, tetracyclin
80 bial mixture of polymyxin B, amphotericin B, nalidixic acid, trimethoprim, and azlocillin (PANTA) was
81 PANTA reagent (polymyxin B, amphotericin B, nalidixic acid, trimethoprim, and azlocillin), reconstit
82 oteins involved in the cytotoxic response to nalidixic acid, we screened for E. coli mutants specific
83 o the selection of the first clinical agent, nalidixic acid, were ever published by the discoverers.
84 he wild, stranded dolphins were sensitive to nalidixic acid, whereas the isolates from the collection
86 repair DNA damage via UV-induced DNA damage, nalidixic acid-induced double-strand breaks, and methyl
87 fraction of kanamycin-resistant (Km(r)) and nalidixic acid-resistant (Nal(r)) isolates showed reduce
89 ompared to 100% of those inoculated with the nalidixic acid-resistant (Nal(r)) parent and 100% of tho
92 758 (38%) were resistant to nalidixic acid (nalidixic acid-resistant S. Typhi [NARST]) and 734 NARST
94 experiments, detection and enumeration of a nalidixic acid-resistant strain of E. coli O157 in bovin
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