ライフサイエンスコーパス: nasopharynx

1 nt sites of isolation (sputum > middle ear > nasopharynx).

2 air contamination or gas conditioned in the nasopharynx).

3 impaired clearance of S. pneumoniae from the nasopharynx.

4 s (meningococcus) is a symbiont of the human nasopharynx.

5 pneumococcus better able to colonize of the nasopharynx.

6 pathogen that frequently colonizes the human nasopharynx.

7 when this bacterium was introduced into the nasopharynx.

8 se and initiates infection by colonizing the nasopharynx.

9 o appears to be required for survival in the nasopharynx.

10 commensal organisms that colonize the human nasopharynx.

11 type increased bacterial colonization of the nasopharynx.

12 r clearance of S. pneumoniae from the murine nasopharynx.

13 st prevalent are the larynx, oropharynx, and nasopharynx.

14 is colonize overlapping regions of the human nasopharynx.

15 nly be carried asymptomatically in the human nasopharynx.

16 se and initiates infection by colonizing the nasopharynx.

17 intercuspal phase of jaw motion, sealing the nasopharynx.

18 of submucosal glands in the upper airway and nasopharynx.

19 ease and within different microniches of the nasopharynx.

20 se and initiates infection by colonizing the nasopharynx.

21 tively metabolizing and growing while in the nasopharynx.

22 ant in adherence and colonization within the nasopharynx.

23 ant to colonize as well as to persist in the nasopharynx.

24 ed significantly reduced colonization of the nasopharynx.

25 b, p < 0.001) after balloon occlusion of the nasopharynx.

26 ropism, and receptors which replicate in the nasopharynx.

27 st and during a breathhold originates in the nasopharynx.

28 itively associated when they co-occur in the nasopharynx.

29 an opportunistic pathogen that colonizes the nasopharynx.

30 h implications for colonization of the human nasopharynx.

31 le preexisting commensal colonization of the nasopharynx.

32 ace and resources during colonization of the nasopharynx.

33 sease, is most commonly carried in the human nasopharynx.

34 Moraxella catarrhalis to colonize the human nasopharynx.

35 diverse pathogen whose primary niche is the nasopharynx.

36 g with reduced macrophage recruitment to the nasopharynx.

37 spite being necessary for clearance from the nasopharynx.

38 asopharynx cancer from other diseases of the nasopharynx.

39 patients there was a mass which narrowed the nasopharynx.

40 reduced ability to survive in the chinchilla nasopharynx.

41 aque variants were less able to colonize the nasopharynx.

42 olonize and is more rapidly cleared from the nasopharynx.

43 d leads to clearance of pneumococci from the nasopharynx.

44 s in the clearance of S. pneumoniae from the nasopharynx.

45 or maintaining meningococcal carriage in the nasopharynx.

46 The bacteria were eliminated from the nasopharynx 1 week earlier than that from the control co

47 ase-deficient mutant was eliminated from the nasopharynx 2 weeks earlier than the D39 parent strain.

48 ence of galactose, a main sugar of the human nasopharynx, a highly competitive microbial environment.

49 s of disease begins with colonization of the nasopharynx, a process that likely depends on bacterial

50 his organism begins with colonization of the nasopharynx, a process that probably depends on adherenc

51 umoniae adherence during colonization of the nasopharynx, a site normally devoid of glucose.

52 Although asymptomatic colonization of the nasopharynx almost invariably precedes disease, the crit

53 ease the duration of viral shedding from the nasopharynx among patients with pneumonia.

54 successful regulation of colonisation in the nasopharynx and a brisk alveolar macrophage-mediated imm

55 NTHI) is a commensal inhabitant of the human nasopharynx and a causative agent of otitis media and ot

56 cus) is a common commensal inhabitant of the nasopharynx and a frequent etiologic agent in serious di

57 neumoniae is a common colonizer of the human nasopharynx and a leading cause of bacterial pneumonia a

58 r to other childhood tumors which affect the nasopharynx and adenoidal hypertrophy.

59 low the kinetics of viral clearance from the nasopharynx and allow for viral interference with antiba

60 To persist in the human nasopharynx and as a pathogen throughout the airways, NT

61 carbon availability is distinct between the nasopharynx and bloodstream of adult humans: glucose is

62 oniae (the pneumococcus) colonizes the human nasopharynx and can cause invasive disease aided by the

63 man pathogen that persistently colonizes the nasopharynx and causes disease when it invades the blood

64 Streptococcus pyogenes can also colonize the nasopharynx and elaborate superantigens.

65 nd chinchilla models of RSV infection of the nasopharynx and Eustachian tube.

66 in and both mutants are able to colonize the nasopharynx and exhibit comparable clearance kinetics.

67 -negative coccobacillus that is found in the nasopharynx and gastrointestinal tract of many wild and

68 e carrier sclA allele persisted in the mouse nasopharynx and had increased adherence to cultured epit

69 n association between viral detection in the nasopharynx and hospitalization for pneumonia.

70 c changes in diameter were often seen in the nasopharynx and in the hypopharynx of asymptomatic sleep

71 curate lesion conspicuity (especially in the nasopharynx and in the larynx), infiltration of adjacent

72 essential for colonization of the chinchilla nasopharynx and infection of the middle ear.

73 passages of bacteremic rats to colonize the nasopharynx and invade the bloodstream.

74 influenza A virus infection to colonize the nasopharynx and invade the middle ear in the chinchilla

75 of factors required for colonization of the nasopharynx and invasive disease, because of its strict

76 pneumococcus) frequently colonizes the human nasopharynx and is an important cause of pneumonia, meni

77 istent, opportunistic commensal of the human nasopharynx and is the leading cause of community-acquir

78 MRSA colonizes the nasopharynx and is thus exposed to inhalants, including

79 r, rlrA, is required for colonization of the nasopharynx and lung infection but is dispensable for sy

80 een shown to bind to epithelial cells of the nasopharynx and lung, and to endothelial cells of the pe

81 gh the anatomy and microenvironments between nasopharynx and lungs are different, a virulence factor

82 IgA(-/-) mice also cleared virus from the nasopharynx and lungs following heterosubtypic challenge

83 s is likely to be crucial for fitness in the nasopharynx and may play a role during invasive disease.

84 zation and inflammatory responses within the nasopharynx and middle ear chamber.

85 n the ability to colonize and persist in the nasopharynx and middle ear.

86 t association between virus detection in the nasopharynx and pneumonia hospitalization (odds ratio, 1

87 rcinomas of the breast, cervix, colon, lung, nasopharynx and prostate.

88 V3 antibodies, replicated efficiently in the nasopharynx and protected against challenge with wt huma

89 tive diplococcus that normally colonizes the nasopharynx and rarely infects the urogenital tract.

90 phylococcus aureus, a commensal of the human nasopharynx and skin, also causes invasive disease, most

91 umoniae, is required for colonization of the nasopharynx and survival and multiplication in the lung.

92 gitidis, typically a resident of the oro- or nasopharynx and the causative agent of meningococcal men

93 CFU of the SPD0420 mutant were lower in the nasopharynx and the lungs after intranasal infection, an

94 le in colonization and adherence between the nasopharynx and the lungs.

95 strain in its ability to survive in both the nasopharynx and the middle ear of the chinchilla.

96 roteins, with expression present in both the nasopharynx and the middle ear.

97 een the high levels of carriage in the human nasopharynx and the rare incidence of disease.

98 ifference between isolates obtained from the nasopharynx and those obtained from sterile sites (blood

99 decreased its ability to colonize the mouse nasopharynx and to adhere to and be internalized by cult

100 nsal S. pneumoniae to disseminate beyond the nasopharynx and to elicit severe infections of the middl

101 A1 and the D39 parent strain to colonize the nasopharynx and to induce OM subsequent to intranasal in

102 Each strain's ability to colonize the nasopharynx and to induce OM subsequent to transbullar i

103 ls in submucosal glands throughout the mouse nasopharynx and upper airways and AQP4 at the contralate

104 a volume marker present in the fluid-filled nasopharynx and upper trachea.

105 face-expressed proteins downregulated in the nasopharynx (and thus less subject to selection pressure

106 to eukaryotic cells, colonization of the rat nasopharynx, and ability to cause sepsis.

107 osphotyrosine on CpsD when cultured from the nasopharynx, and an O phenotype that phosphorylates CpsD

108 m the eyes, gastrointestinal tract, airways, nasopharynx, and female reproductive tract, thereby stro

109 lar expression on and off (both ways) in the nasopharynx, and group C strains are more likely to be n

110 primarily an obligate commensal of the human nasopharynx, and it is unclear why the bacterium has evo

111 ations into GAS in its 'normal' habitat, the nasopharynx, and its ability to either live with its hos

112 ion, decreased numbers of macrophages in the nasopharynx, and less effective clearance.

113 o reflect successful adaptation to the human nasopharynx, and might provide a paradigm for DNA repair

114 All meningococci are carried in the nasopharynx, and most genotypes are very infrequently as

115 microbial communities (such as patient skin, nasopharynx, and stool) as well as environmental biofilm

116 al sites such as the intestine, oral cavity, nasopharynx, and vagina all have associated commensal fl

117 i) is a commensal microorganism of the human nasopharynx, and yet is also an opportunistic pathogen o

118 I) lung, (II) lung and blood, (III) lung and nasopharynx,and (IV) all three tissues were identified,

119 tion, whereby pneumococci harvested from the nasopharynx are typically transparent, while those simul

120 t human pathogens that commonly colonize the nasopharynx, are naturally competent for DNA uptake from

121 ptococcus pneumoniae naturally colonizes the nasopharynx as a commensal organism and sometimes causes

122 reptococcus pneumoniae commonly inhabits the nasopharynx as a member of the commensal biofilm.

123 S. pneumoniae to colonize and persist in the nasopharynx as well as the middle ear.

124 cluding regions of the respiratory tract and nasopharynx, as well as in a subset of lung tumour cell

125 (NTHI) bacteria are commensals in the human nasopharynx, as well as pathogens associated with a spec

126 l vertebrates such as birds and mammals, the nasopharynx-associated lymphoid tissue (NALT) represents

127 atory epithelium covering nasal passages and nasopharynx-associated lymphoid tissue than H5N1 viruses

128 2 (but not CK10 or CK13) expression in trout nasopharynx-associated lymphoid tissue.

129 Nasopharynx auditory tube glands fail to develop in HED

130 ved also in colonization and invasion of the nasopharynx, biofilm formation and evasion of host immun

131 occus pneumoniae is a commensal of the human nasopharynx but can cause invasive diseases, including o

132 ay aid in the persistence of NTSp within the nasopharynx but is not involved in invasion.

133 a commensal microbe that colonizes the human nasopharynx but occasionally invades the bloodstream to

134 plicated in virulence and persistence in the nasopharynx, but its role in biofilms has not been studi

135 n micro-dissected compartments of the bovine nasopharynx by microarray.

136 Colonization of the human nasopharynx by Moraxella catarrhalis is presumed to invo

137 Colonization of the nasopharynx by S. pneumoniae precedes pulmonary and othe

138 orrelation between colonization of the human nasopharynx by Streptococcus pneumoniae and Haemophilus

139 Asymptomatic colonization of the nasopharynx by Streptococcus pneumoniae precedes pneumoc

140 osis and differential diagnosis of childhood nasopharynx cancer from other diseases of the nasopharyn

141 ribution of MR imaging features of childhood nasopharynx cancer.

142 ry of the agent came first as in stomach and nasopharynx cancers, and epidemiology has been concerned

143 ysis by the Meta-Analysis of Chemotherapy in Nasopharynx Carcinoma (MAC-NPC) collaborative group to a

144 ighlights how the bacterial ecosystem of the nasopharynx changes the nature and course of pneumococca

145 licA and igaB are important for early human nasopharynx colonization.

146 ts verified that the surface pH of the human nasopharynx could be transiently lowered to pH approxima

147 f anti-S. pneumoniae responses in the murine nasopharynx during colonization.

148 S. pneumoniae adhesion to and invasion into nasopharynx epithelia, for its ability to induce protect

149 ere observed in the complex epithelia of the nasopharynx, esophagus, colon, and bladder, with Bak imm

150 es from the airways, gastrointestinal tract, nasopharynx, female reproductive tract and the surface o

151 e production and cellular recruitment to the nasopharynx following colonization.

152 oping neoplasms from radium treatment of the nasopharynx for adenoid hypertrophy.

153 Heavy nasopharynx foreign body load and loss of gland protecti

154 ldren with additional Gram + bacteria in the nasopharynx (Gr+/-).

155 number of NTSp isolates colonizing the human nasopharynx has been observed, but the colonization fact

156 We conclude that carbon availability in the nasopharynx impacts pneumococcal biofilm formation in vi

157 found to be required for colonization of the nasopharynx in a carriage model.

158 l cells, and enhanced clearance in lungs and nasopharynx in a mouse aerosol challenge model.

159 l cells, and enhanced clearance in lungs and nasopharynx in a mouse aerosol challenge model.

160 s been implicated in the colonization of the nasopharynx in an infant rat model of carriage.

161 pneumonia and to prevent colonization of the nasopharynx in animal models.

162 y be expressed on the mucosal surface of the nasopharynx in bactericidal concentrations.

163 serious disease and common colonizers of the nasopharynx in children.

164 irulence and higher capacity to colonize the nasopharynx in healthy individuals.

165 unilateral pharyngeal tonsil and ipsilateral nasopharynx in one).

166 thelium of the dorsal soft palate and dorsal nasopharynx in persistently infected cattle.

167 gene on the epithelial surface of the human nasopharynx in situ and inducible transcription in epith

168 orrelated with their ability to colonize the nasopharynx in vivo, with colonization-deficient strains

169 s required for efficient colonization of the nasopharynx in vivo.

170 Pathogens that colonize the nasopharynx, including Staphylococcus aureus, Streptococ

171 arious neisserial co-colonizers of the human nasopharynx increased N. meningitidis switching frequenc

172 colonization experiments of murine lung and nasopharynx, indicating a role for raffinose and stachyo

173 e mutant is more attenuated than scrH in the nasopharynx, indicating SusH can substitute in this nich

174 Asymptomatic carriage in the nasopharynx is a prerequisite for disease, but variabili

175 the connection between the nasal airway and nasopharynx is completely blocked.

176 f Haemophilus influenzae type b to the human nasopharynx is facilitated by Hib pili, filaments expres

177 g how NTSp colonizes and survives within the nasopharynx is important due to the increase in NTSp car

178 t Streptococcus pneumoniae colonization, the nasopharynx is sampled using a swab placed in skim milk-

179 Colonization of the nasopharynx is the initial step in all infections caused

180 The human nasopharynx is the main reservoir for Streptococcus pneu

181 propose that the default role for DC in the nasopharynx is to maintain tolerance/ignorance of the la

182 specific function in the colonization of the nasopharynx is unknown.

183 human upper respiratory tract, including the nasopharynx, is colonized by a diverse array of microorg

184 including human epidermoid carcinoma of the nasopharynx (KB) and its etoposide-resistant (KB7B) and

185 rcinoma (A-549), epidermoid carcinoma of the nasopharynx (KB), renal cancer (CAKI-1), and melanoma ca

186 e and forms highly organized biofilms in the nasopharynx, lungs, and middle ear mucosa.

187 Its adaptation for survival in the human nasopharynx makes the meningococcus a highly successful

188 mited areas of the surface epithelium of the nasopharynx may have important implications in the patho

189 of pneumococci of various serotypes from the nasopharynx mediated by the cytokine IL-17A.

190 ariants have been shown both to colonize the nasopharynx more efficiently in an animal model and to e

191 can be reliably measured in the oesophagus, nasopharynx, mouth, and bladder.

192 ological features of childhood tumors of the nasopharynx must be well known.

193 the sinus (n = 5), the ear (n = 2), and the nasopharynx (n = 18); isolates were recovered from 49 ch

194 An increase in Streptococcus pneumoniae nasopharynx (NP) colonization density during a viral coi

195 The nasopharynx (NP) is a reservoir for microbes associated

196 moniae is a commensal colonizer of the human nasopharynx (NP) that causes disease after evasion of ho

197 e oral cavity (OSCC), oropharynx (OPSCC) and nasopharynx (NPC).

198 while virus selectively persisted within the nasopharynx of a subset of animals.

199 Its normal habitat is the nasopharynx of adult humans.

200 enzae, both of which frequently colonize the nasopharynx of children, were more common in females, su

201 ll drug-resistant pneumococci colonizing the nasopharynx of healthy children attending day care.

202 of M. catarrhalis strains, isolated from the nasopharynx of healthy children or middle ear effusions

203 umoniae (the pneumococcus) is carried in the nasopharynx of healthy individuals, but can spread to ot

204 of meningococcal isolates recovered from the nasopharynx of human carriers.

205 in NTHi 2019Str(R)1 was used to colonize the nasopharynx of human subjects in a study of experimental

206 Streptococcus pneumoniae colonizes at the nasopharynx of humans and is able to disseminate and cau

207 igosaccharides prevented colonization of the nasopharynx of infant rats.

208 As the flora residing in the nasopharynx of infants can be in contact with ingested f

209 The nasopharynx of infants is a major ecological reservoir o

210 f the cop operon is induced in the lungs and nasopharynx of intranasally infected mice, and a copA(-)

211 number of interfering organisms found in the nasopharynx of smokers revert to normal levels after com

212 sms were recovered from the nasal cavity and nasopharynx of the animals in numbers sufficient for DNA

213 s and an isogenic TFP mutant to colonize the nasopharynx of the chinchilla.

214 ogether, our observations highlight that the nasopharynxes of children in DCCs are a melting pot of s

215 reptococcus pneumoniae cocolonization in the nasopharynxes of humans can be attributed to hydrogen pe

216 and experiments where S. aureus invaded the nasopharynxes of rats with established S. pneumoniae pop

217 or the autocthonous S. aureus colonizing the nasopharynx or conjunctiva or lid margin to be a reservo

218 te wire swab either nasally to the posterior nasopharynx or orally to the posterior oropharynx.

219 in the lungs but not for colonization in the nasopharynx or replication in the bloodstream during sep

220 ORF3 in HT29.14S (colon), HeLa (cervix), KB (nasopharynx), or LNCaP (prostate) cancer cell lines, in

221 Motion of the nasopharynx, oropharynx, and hypopharynx was characteriz

222 The nasopharynx, oropharynx, and hypopharynx were characteri

223 rates from 29 cancers: lip and oral cavity; nasopharynx; other pharynx; esophageal; stomach; colon a

224 M. catarrhalis to survive in the chinchilla nasopharynx over a 3-day period.

225 ); and mean change in airway diameter of the nasopharynx (P <.001) and hypopharynx (P <.001).

226 otion in the oropharynx (P =.006) and in the nasopharynx (P <.006) but not in the hypopharynx (P =.65

227 airways (including the paranasal sinuses and nasopharynx) play an important role as a silent reservoi

228 ssociated with cancer of the nasal cavities, nasopharynx, prostate, lung, and pancreas; however, thes

229 n blocks NTHI colonization of the chinchilla nasopharynx, providing the first demonstration of a role

230 and who had tissue diagnosis and MRI of the nasopharynx region.

231 LD2 is expressed in the mandible, palate and nasopharynx regions during craniofacial development at E

232 sparent, selected for in the bloodstream and nasopharynx, respectively.

233 TRAF-4 immunopositive, including epidermis, nasopharynx, respiratory tract, salivary gland, and esop

234 in which we collected questionnaires and 324 nasopharynx samples from 20 infants with CF and 45 age-m

235 Individuals harbouring bacteria in the nasopharynx serve as reservoirs for intrafamilial and no

236 the 148 subjects (mean age, 3.4 years), the nasopharynx showed dynamic motion in 53 (36%).

237 ubclinical bacterial colonization within the nasopharynx, similar to IAV.

238 following parameters between the two groups: nasopharynx SP (P <.001) and IC (P <.001); hypopharynx S

239 dispersal include IAV-induced changes in the nasopharynx, such as increased temperature (fever) and e

240 tion of mice and were unable to colonize the nasopharynx, suggesting a diminished capacity to sense o

241 e infections and were unable to colonize the nasopharynx, suggesting that the failure to produce caps

242 4 isolate during cocolonization in the mouse nasopharynx, suggesting that the locus is functional in

243 most frequently detected pathogen in either nasopharynx swab specimens, stool specimens, serum sampl

244 mpled with a bronchoscope were higher in the nasopharynx than at the epiglottis or in the trachea in

245 holding increased to a greater extent in the nasopharynx than in the pharynx or trachea.

246 enzae is a human-restricted commensal of the nasopharynx that can also be associated with disease.

247 ommunities during colonization of the murine nasopharynx that display increased antibiotic resistance

248 For example, in the nasopharynx the wild-type serotype 3 strain and the caps

249 that augmented bacterial clearance from the nasopharynx, the middle ears, or both anatomical sites c

250 ompetence pathway during colonization of the nasopharynx, the principal ecological niche of the pneum

251 ectly within the physical environment of the nasopharynx, thereby explaining why lineage structure is

252 occasion, meningococci disseminate from the nasopharynx to cause invasive disease.

253 by the bacterium during progression from the nasopharynx to the blood.

254 rbon caused S. pneumoniae to spread from the nasopharynx to the lungs, which is essential for subsequ

255 th the dissemination of pneumococci from the nasopharynx to the middle ear.

256 thymus and respiratory epithelium including nasopharynx, trachea and bronchi.

257 ficantly lower numbers of pneumococci in the nasopharynx, trachea, and lungs.

258 ant effects on pneumococcal infection of the nasopharynx, trachea, and lungs.

259 SK2a-expressing strains are associated with nasopharynx tropicity, and many of these strains express

260 hat distinguish between strains that use the nasopharynx versus an impetiginous lesion as their prima

261 early, complete eradication of NTHI from the nasopharynx was highly protective, reduction of the bact

262 to induce total eradication of NTHI from the nasopharynx was not equivalent among NTHI groups.

263 late moved upward as the jaw opened, but the nasopharynx was not sealed.

264 Further, bacterial colonization of the nasopharynx was prevented in mice immunized with HA-KO/P

265 NTHI residing in the nasopharynx was rapidly cleared from this site, thus pre

266 C of the oral cavity, oropharynx, larynx, or nasopharynx was used.

267 M. catarrhalis to persist in the chinchilla nasopharynx were upregulated in the mesR mutant.

268 ued adherence of H. influenzae type b to the nasopharynx, where the three-stranded Hib pilus filament

269 of adult humans: glucose is absent from the nasopharynx, whereas galactose is abundant.

270 Unlike the phase variants detected in the nasopharynx, which have at least 20% of the parental amo

271 nces pneumococcal colonization of the murine nasopharynx, which in turn promotes bacterial spread to

272 ltiple pneumococcal strains can colonize the nasopharynx, which is also home to many other bacterial

273 hat CTB reduces the pneumococcal load in the nasopharynx, which required activation of the caspase-1/

274 h as influenza, leads to inflammation in the nasopharynx with an increased temperature and recruitmen

275 gitidis is a frequent colonizer of the human nasopharynx, with asymptomatic carriage providing the re

276 may extend to the resident microbiota of the nasopharynx, with implications for the pathogenesis of r

277 ms by which S. pneumoniae colonize the human nasopharynx without inducing damaging host inflammation

278 nt infection or a carrier state in the human nasopharynx without overt disease symptoms but the prese