ライフサイエンスコーパス: native

1 dividuals and in American Indians and Alaska Natives.

2 he cryo-electron microscopy structure of the native 100S ribosome from S. aureus, revealing the molec

3 nteractions of 2-5-linkages comparing to the native 3-5-linkages.

4 his interaction in a background in which the native A. thaliana CENH3 is replaced with CENH3s from di

5 The presence of native acrylamide was confirmed by mass analysis at m/z=

6 atures between the model NiAz system and the native ACS enzyme, highlighting the potential for relate

7 f empty capsids that migrated more slowly in native agarose gel electrophoresis from A36V mutant than

8 of death among American Indians and Alaskan Natives (AIAN), although cancer survival information in

9 m-F-alb") had the smallest size and the most native albumin, thus showing the most favorable cell int

10 with a high prevalence of comparatively rare native algal species.

11 The native algal structure resembles the in vitro mammalian

12 urfactants) and neutral cyclodextrins (i.e., native alpha-, beta-, or gamma-cyclodextrin) is presente

13 ere we directly test the hypothesis that the Native American admixture of the current Rapa Nui popula

14 uan individual shares more alleles with some Native American groups in South America than with Native

15 ation in human STAC3 causes the debilitating Native American myopathy (NAM), but the nature of how St

16 were Hispanic; 13, African; 8, white; and 2, Native American.

17 e American groups in South America than with Native Americans elsewhere, providing further support fo

18 scent populations but not among Europeans or Native Americans.

19 and MMP-9 was redesigned to incorporate non-native amino acids (Flp and mep), resulting in an increa

20 scale-dependence of the observed changes for native and alien species.

21 or the peptic-tryptic digest of gliadin (in native and deamidated forms) before T-cell collection.

22 Crystal structures and TPS dynamics of native and F159Y PNPs explore the catalytic-site geometr

23 mitogenomes of 89 House Crows spanning four native and five invasive populations.

24 -resolution open chromatin profiling on both native and formaldehyde-fixed cells.

25 we provide a protocol for isolating GVs from native and heterologous host organisms, functionalizing

26 Testing for environmental similarity between native and invaded areas is critical to identifying nich

27 es induced by the R61T mutation in the ApoE4 native and misfolded states.

28 n between a subset of coregulators with both native and mutant forms of ER.

29 r elongation when compared to films based on native and single acid modified starches.

30 in oil-in-water emulsion and compared to the native and soy lecithin.

31 nd in vitro imaging in the space between the native and THV leaflets (neosinus).

32 er derivatives from concurrently metabolized native and uniformly labeled tracer substances.

33 because the approach utilizes conjugation to native antibody cysteine residues, it is widely applicab

34 ved from post-translational modifications of native antigens are emerging as novel targets that are m

35 he ITs demonstrated specific binding against native antigens on persistently HIV-infected cells and r

36 te the timing of the observed artifacts with native aortic valves.

37 From the pure native AR TAVR multicenter registry, procedural and clin

38 analysis revealed that the RxLR sequence of native AVR3a is cleaved off prior to secretion by the pa

39 1D) has focused on peptides originating from native beta cell proteins.

40 that hydrolysis yielded an intermediate (non-native) beta-Lg state.

41 Whereas incorporation of the native bilin phytochromobilin into PhyB confers robust P

42 trates their strategic value in safeguarding native biodiversity.

43 quantitative analysis of lysine residues in native biological systems.

44 ng an unprecedented coverage of system-wide, native biomolecules.

45 ts calcifying in vivo to a similar extent as native bone.

46 Bs lose niche position and relocate to a non-native brain region that is rich in neurosecretory neuro

47 For native BSA/curcumin, fluorescence indicated an enthalpic

48 tion of C3 is mediated by direct cleavage of native C3 by mannan-binding lectin-associated serine pro

49 Native cargo proteins exit the endoplasmic reticulum (ER

50 sues that are morphologically reminiscent of native cartilage.

51 wn about the ancestry and history of Russian native cattle.

52 oengineered artificial ducts can replace the native CBD, with no evidence of cholestasis or occlusion

53 te various strategies for the preparation of native CDs-modified inorganic nanomaterials such as meta

54 n of cells within a larger culture, allowing native cell-to-cell contact and communication even durin

55 One difference between native cells and cell lines was the time absent from a f

56 for the existence of mGlu2-4 heterodimers in native cells.

57 Integration of stem cell-derived cells into native cellular environment remains a challenge in the f

58 mpetition of nonnative stabilization against native-centric forces is conceptualized as frustration.

59 In patch-clamp experiments using native cerebral arterial myocytes, membrane stretch-indu

60 soma macropomum, or tambaqui, is the largest native Characiform species found in the Amazon and Orino

61 mandibular first premolars extracted from a native Chinese population were collected, scanned using

62 n source with an ion trap mass spectrometer, native cholesterol in its free alcohol form is readily d

63 n and entirely lost upon RNaseA digestion of native chromatin.

64 ith reaction rates comparable to that of the native cofactors.

65 tress to the most susceptible populations of native coldwater fish appears to be shifting from acidif

66 ing century - can stress and ultimately kill native coldwater fish in lakes where thermal stratificat

67 pically competitively superior to members of native communities that are least-closely related to the

68 olution, resulting in devastating effects on native communities.

69 plant tissue mineralization in invasive and native communities; the rest of the CO2 was produced fro

70 ess and effects of the non-native species on native community structure and ecosystem properties were

71 SOM priming in the native community was proportional to belowground biomass

72 an invasive forb, Alliaria petiolata, and a native competitor, Pilea pumila, may affect their long-t

73 imizing both the affinity and specificity of native complex structures.

74 ptimized to maintain the proteins studied in native conditions and enable sharp pH changes in order t

75 ray ionization mass spectrometry (ESI-MS) in native conditions to study the influence of modification

76 undergo significant changes in volume under native conditions while exhibiting no additional changes

77 inding region of the P73G mutant, even under native conditions, was markedly disordered, suggesting t

78 We show that under native conditions, where both the self-targeting and nat

79 ble of folding an H3-H4 dimer in vitro under native conditions.

80 ogenous SUMOylated proteins under completely native conditions.

81 ate that the D145E mutation destabilises the native conformation of EF-hand IV, leading to a transien

82 d eventually inserted into the membrane in a native conformation.

83 d the disulfide connectivity underlying E1E2 native conformation.

84 roteins and other biomacromolecules in their native conformations.

85 We show that only the native conformer of benenodin-1 is cleaved by its cognat

86 to target other redox-active side chains for native conjugation.

87 ation of a 3D human lymphatic network within native connective tissue devoid of any exogenous materia

88 sing primarily on the pairs with the largest native contact surfaces, H1-H2 and H1-H4.

89 he ligand has just broken the most important native contact with the receptor.

90 the regulatory activity of 3'-UTRs in their native context.

91 synergy with multipartite contacts with the native core of HspQ, is required for allosteric Lon acti

92 onditions, where both the self-targeting and native crRNAs are expressed, self-targeting by CRISPR-Ca

93 de toxins successfully reverted back to near-native crystallographic poses after being perturbed.

94 ization between introduced rainbow trout and native cutthroat trout in western North America will lea

95 Comparison of atomistic models of a native cyanobacterial form (Thermosynechococcus vulcanus

96 e of a straightforward strategy to interface native d-DNA with its enantiomer l-DNA-oligonucleotides

97 hermore, transplantation of hDF-EpiSC-loaded native de-cellularized rat parotid gland scaffolds into

98 tudies that these constructs mature to match native disc composition, structure, and function with lo

99 Peptides that contained only two native disulfide bonds lack the characteristic granulin

100 etion of proteins that are known to form non-native disulfides during their folding.

101 (Japanese barberry), each paired with their native ecological analogs to better understand demograph

102 Although context dependent, these native ecosystems subjected to prolonged invasion by exo

103 Overall, the properties of native egg phospholipids were significantly enhanced in

104 hat closely mimic the material properties of native elastin.

105 tochondrial synthasomes were investigated by native electrophoresis, immunoprecipitation, and sucrose

106 lso been made as a soluble form to mimic the native Env present on the virion surface.

107 all conformation is similar to SOSIP.664 and native Env trimers but includes a covalent linker betwee

108 termine the transition state sampling in the native enzyme, in accordance with a Born-Oppenheimer-lik

109 had enzymatic kinetics similar to the olive native enzyme.

110 es bidirectional activity reminiscent of the native enzyme: the complex activates H2 under mild condi

111 For native enzymes displaying nonadiabatic tunneling, the do

112 eme metal ions beyond the Cu and Fe found in native enzymes has provided deeper insights into nature'

113 e presence of disorder in several functional native enzymes.

114 transcriptional activity of alpha-SYN in its native epigenetic landscape which is not achievable usin

115 trum from the extended unfolded state to the native fold, yielded nearly 120 mus of cumulative sampli

116 its low starch digestibility similar to its native form ( approximately 25% SDS; approximately 60% R

117 These cilia beat at a native frequency and in a synchronized pattern to contin

118 influence past extirpation probabilities of native freshwater fishes in the Upper and Lower Colorado

119 f macromolecular complexes inside cells in a native frozen-hydrated state.

120 gical samples such as intact cells in a near-native, frozen-hydrated state to macromolecular resoluti

121 tial of plasmonics by exploiting an enhanced native functionality - the majority voter.

122 Here, we show by blue-native gel electrophoresis and stable isotope labeling i

123 We found that both proteins co-migrated in native gels in a complex of approximately 200 kDa that a

124 nvestigate the microstructural parameters of native gels, electron microscopy image analysis were per

125 phenotypic readout of enhancer function in a native genomic context reveals novel features of CRM fun

126 DNA libraries are constructed using native genomic DNA from any source of interest, preservi

127 red, and even well-folded proteins adopt non-native geometries during synthesis, folding, transport,

128 T cells in children recognize deamidated and native gluten epitopes, whereas T cells from adults only

129 trogen limitation and can be advantageous in native habitats of Synechocystis.

130 isture content and water solubility than the native high amylose starch film.

131 ysis of a recombinant, trimeric mimic of the native HIV-1 viral spike (BG505 SOSIP.664) compared to t

132 erent panicoid rDNA units in addition to the native Hordeum rDNA copies.

133 produce key electrophysiological features of native human ventricle, which, along with specific selec

134 mary tumors that otherwise were resistant to native IL-21 treatment.

135 bject-matched tooth and implant sites during native inflammation and in response to experimental plaq

136 of Bayesian demographic modelling shows that native insect herbivores consistently prevent hard-to-pr

137 novel zinc-free hexamer at 2.8 A, revealed a native insulin fold with incomplete or absent electron d

138 e energetic favorability of nonnative versus native interactions, we compute free energies of associa

139 s, eliminating the possibility of monitoring native interactions.

140 JSmol, its reincarnation based on native JavaScript, has a predominant position in the pos

141 We also study the distribution patterns of native KCNQ1 and KCNE1, and their relationship to IKs am

142 Serum paraoxonase 1 (PON1) is a native lactonase capable of promiscuously hydrolyzing a

143 g-especially before age 6-and English as the native language.

144 platelet reactivity (HPR) in SVG PCI versus native lesion PCI is unknown.

145 1 binds in a position that overlaps with the native ligand adenosine, but its methoxyphenyl group ext

146 ered inverse agonist (11-cis-retinal) as the native ligand.

147 .e., independently of receptor occupation by native ligand.

148 d exchange methods, which completely replace native ligands with functionalized cinnamate ligands, al

149 acid-level dynamics biased toward selecting native-like interactions.

150 to determine the collision cross sections of native-like ions of proteins and protein complexes, whic

151 The results indicate that in a native-like lipid environment rhodopsin activation is no

152 assemblies in which the protein retains its native-like structure, which subsequently convert into a

153 t least nine unique species: three native or native-like structures; two that appear to be equilibriu

154 Native-like trimers of the SOSIP design are being develo

155 structure-guided design to develop improved native-like trimers that reduce exposure of non-nAb epit

156 with the rest of the alpha-domain remaining native-like.

157 nd regioselectivity as well as result in non-native linkages that may suffer from instability in vivo

158 of individual bacteriorhodopsin molecules in native lipid bilayers.

159 tameric ligand-gated ion channel imaged in a native lipid membrane.

160 flow and regeneration between the graft and native liver along with multiple refinements in surgical

161 populations had been transferred from their native location to a planting site.

162 dent and occurred even in the absence of its native lumenal domain.

163 ctionalities (Ga-10:1 NOTA-somatropin); (ii) native mass spectrometry (MS) offered in-depth informati

164 Here the authors show that native mass spectrometry and high resolution electron mi

165 irst demonstration is provided of the use of native mass spectrometry for screening fragments against

166 OMP (tOmpA) using fluorescence spectroscopy, native mass spectrometry, and molecular dynamics simulat

167 study, Remicade and Remsima were examined by native mass spectrometry, ion mobility, and quantitative

168 Here, we combine X-ray crystallography, native mass spectrometry, single-channel electrical reco

169 rofile of C9 was acquired by high-resolution native mass spectrometry, which revealed the co-occurren

170 cs shows the characteristics observed in the native membranes, and is described by a multisquare mode

171 roperties of particular nucleosomes in their native molecular environment.

172 s than those previously demonstrated for the native molecule.

173 Abundant pollination by a previously unknown native moth in experimental and restored populations sug

174 mass spectrometer, enabling high-resolution native MS analysis of 0.8- to 2.3-MDa prokaryotic 30S, 5

175 Native MS detection was used to determine the sample oxi

176 brium affinity constant was determined using native MS, revealing a nearly eightfold enhancement in d

177 entary photophysical behavior to that of the native NAD(+)/NADH.

178 be hijacked to induce the degradation of non-native neo-substrates using bivalent compounds known as

179 binding increases occupancy of GluN1/2A and native NMDAR desensitized states entered after accumulat

180 Remarkably, the native NMR spectrum returns with this slower time consta

181 Native North American grasses are commonly inhabited by

182 dent interaction with chromatin, we purified native nucleosomes from mouse ES cells and detect that S

183 er incorporation kinetics of non-fluorescent native nucleotides by DNA polymerases.

184 individual alpha-SYN protein and assess its native oligomerization states from biological samples in

185 PUT takes advantage of the high native optical contrast among biological tissues and can

186 ; however low amylose rice starches, whether native or acetylated, did not form films with desirable

187 r hydrophobic substrates in a detergent-free native or artificial membrane environment.

188 nvolving at least nine unique species: three native or native-like structures; two that appear to be

189 ydrocarbamazepine were demonstrated with the native organism and a recombinant host.

190 es and three-dimensional structure mimicking native organs.

191 demonstrate that TFIID alone binds poorly to native p53 target promoters.

192 molecular mass estimated, using SDS-PAGE and native-PAGE electrophoresis, to be 86kDa.

193 molecular similarities of mutant clones with native PanINs, and identifies potential PanIN biomarker

194 ng antigens on their surfaces, mimicking the native pathogens.

195 sian/Pacific Islander/American Indian/Alaska Native patients.

196 sian/Pacific Islander/American Indian/Alaska Native patients; but after adjusting for baseline charac

197 ecific responses and neutralization than the native peptide epitope.

198 presumably higher energy conformations than native peptide-MHC complexes.

199 n ring (oxetane) can be readily grafted into native peptides and proteins through site-selective bis-

200 Furthermore, 4E native peptides were used as additive to deposit Au nano

201 At native pH of 8.6, the anoxic fraction, despite its signi

202 transfer has never been demonstrated in any native photosynthetic system.

203 In mesocosms, native plankton communities were connected by low or mod

204 An extract of the Texas native plant Amyris texana was found to have selective a

205 he potential for restoration to re-establish native plant-pollinator interactions critical for produc

206 n the relative and total fruit production of native plants.

207 of models calibrated with native vs. pooled (native plus invaded) species records.

208 Using native polyacrylamide gel shift assay and negative-stain

209 to migrate appropriately on both agarose and native polyacrylamide, unlike many currently available D

210 ctal cells through epigenetic editing of the native promoter.

211 ged and expressed under the control of their native promoters, localized in the cytoplasm of pollen g

212 cle termed 'Nano-CarboScavengers' (NCS) with native properties for facile recovery via booms and mesh

213 knowledge-based potentials in selecting the native protein structures from decoy sets.

214 ID), for the top-down MS characterization of native protein-ligand and protein-protein complexes.

215 apoptotic cells at a level comparable to the native protein.

216 fficaciously blocked reticulocyte binding of native PvRBPs, suggesting that the human immune system p

217 uorescent proteins within GSDMD that support native pyroptosis and facilitate live-cell imaging of py

218 rts representation of ontological objects by native R types, and provides a parsimonius set of perfor

219 The population dynamics in the native range and invaded range show no evidence of cycli

220 vasive common wasp, Vespula vulgaris, in its native range in England and its invaded range in New Zea

221 he new region resemble those of the species' native range.

222 Native, reassembled and succinylated milk proteins were

223 althy subjects do not compete for binding on native receptor.

224 fter injury, SCI induced upregulation of the native regulator of CaN 1 (RCAN1) in the DRG at the tran

225 tability changes through upregulation of the native regulator of CaN 1 (RCAN1).

226 inators, could also hasten the extinction of native remnant plants in urban settings, or whether they

227 ophila, in which the mouse OPN4 replaced the native Rh1 photopigment of Drosophila R1-6 photoreceptor

228 30S assembly and simplify the search for the native ribosome structure.Ribosomes assemble through the

229 determining the structure without distorting native RNA fold.

230 modifications to the PIV5 backbone, replace native RSV F with a prefusion-stabilized RSV F mutant, o

231 in Arg and Trp residues, and able to adopt a native RTD-1-like structure.

232 Bioengineering intestine on vascularized native scaffolds could bridge the gap between cell/tissu

233 Filamentous fungi are native secretors of lignocellulolytic enzymes and are us

234 the discovery of an 11-mer peptide with the native sequence of ArcA that repressed expression of fim

235 Acute native shortened modified look-locker inversion recovery

236 ein sequences, through which a subset of the native side chains is displayed on an unnatural building

237 hat uses nanomolar protein concentrations in native solutions.

238 t histories of individual cells within their native spatial context is a long-standing challenge in b

239 consisted of a) patients >/=18 years of age, native speaking, hospitalized for at least 24h, alert an

240 ersely, eT increased silicon accumulation in native species (+19%) but decreased silicon accumulation

241 over, declines in silicon occurred mainly in native species (-19%), but remained largely unchanged in

242 tings of nonnative plants, largely excluding native species from cropland.

243 ommon invasive shrub, and similar impacts on native species might occur in its invasive range, or in

244 establishment success and effects of the non-native species on native community structure and ecosyst

245 o yield dispersal rate-driven differences in native species richness prior to invasion by a non-nativ

246 a prerequisite for the establishment of non-native species that become invasive, so knowledge of com

247 of invasive species and the most susceptible native species to their establishment do not match at la

248 or by reducing the competitive abilities of native species.

249 ignored when forecasting the dynamics of non-native species.

250 source region relative to a control without native species.

251 gelatinization temperatures and enthalpy of native starch were 59.9, 71.3, and 80.6 degrees C and -1

252 bed in terms of transitions between a folded native state and less-populated intermediates, or excite

253 foreshadowed by segmental flexibility in the native state as probed by heteronuclear NMR spectroscopy

254 and suggests that the general concept of the native state be expanded to allow for more variable phys

255 at both proteins exist as tetramers in their native state before and after proteolysis.

256 hanged to its NIS-bound state instead of the native state.

257 regates and assist in their refolding to the native state.

258 es for each to propagate to the final folded native state.

259 ective lens to image frozen samples in their native state.

260 responding to the denatured, transition, and native states in the folding of the activation domain of

261 vailable information suggests that quantized native structure and stepwise folding coevolved in ancie

262 , in isolation, IL-12alpha fails to form its native structure but, instead, misfolds, forming incorre

263 RACER achieves accurate native structure prediction for a number of RNAs (averag

264 ompact monomer with little similarity to the native structure.

265 likely similarity between the predicted and native structures of proteins have become essential for

266 we identify and characterize two alternative native structures, three intermediate states, and numero

267 structure and derive a criterion to identify native structures.

268 l to discriminate between 3',5'-cAMP and the native substrate AdoMet.

269 king of the drug colchicine into tubulin and native sulfur phasing of the human G protein-coupled ade

270 ) ions and the nanochannel walls reduced the native surface charge density by up to approximately 4-5

271 ficient (p < 0.001), and 4.7-ms increment in native T1 (p = 0.001).

272 e sought to investigate the ability of acute native T1 mapping to differentiate reversible and irreve

273 rval [CI], -1.6 to 1.3) and AAR derived from native T1 maps (bias=1; 95% CI, -0.37 to 2.4).

274 Children after rTOF do not have elevated LV native T1 or LV extracellular volume, but show evidence

275 ar volume, but show evidence of increased RV native T1 suggestive of diffuse RV fibrosis, for which v

276 nding areas at day 21 demonstrated for early native T1 values the best correlation with the later fun

277 nomer retained the same overall structure of native TGF-beta monomers and bound TbetaRII in an identi

278 he first report of TA receptor function in a native tissue and indicates unexpected complexity in the

279 with tensile properties approaching those of native tissue.

280 l to emulate the electromechanical milieu of native tissues or conform well with the curved topology

281 It appears that reducing the flexibility of native Tm coiled-coil structure decreases the optimum in

282 he protein population, the transition from a native to an amyloid-like structure occurs within the ag

283 Paullinia cupana is a plant native to Brazil that is widely used in traditional medi

284 Teff (Eragrostis tef) is a cereal native to Ethiopia and Eritrea.

285 l and total phenols were found for genotypes native to Mexico (like RIM105, M031, and M033) or from P

286 Staghorn sumac (Rhus typhina) is native to North America, and has been used by indigenous

287 Butia odorata is a palm tree native to southern Brazil whose fruit (known as butia) a

288 with measured traits from chaparral species native to Southern California, shows that apparently sim

289 While the native toxin is extremely lethal, bioengineering of BoNT

290 bioactivity and receptor binding kinetics as native TRAIL in vitro which are 4-5 orders of magnitude

291 harmacodynamic profiles in vivo than that of native TRAIL.

292 p120s and against DS-SOSIP, which mimics the native trimer.

293 atform termed CANscript, which preserves the native tumor heterogeneity, in order to interrogate the

294 safety of TMVR in a cohort of patients with native valve MR who were at high risk for cardiac surger

295 ge of Phragmites australis roots deeper than native vegetation (Schoenoplectus americanus and Spartin

296 e capsid protein VP3, which is hidden in the native virus.

297 method, single-channel current amplitude of native voltage-gated calcium channels can be resolved ac

298 ed the performance of models calibrated with native vs. pooled (native plus invaded) species records.

299 ion that in addition to inhibiting chymosin, native whey proteins present a physical barrier to para-

300 species richness prior to invasion by a non-native zooplankter, Daphnia lumholtzi.