ライフサイエンスコーパス: natural

1 Bacteria have the natural ability to install protective postsynthetic modi

2 For example, although natural Abs (NA) and complement are key components of th

3 ligand 2 (PD-L2) regulates the production of natural Abs against phosphorylcholine (PC).

4 easure residual dipolar couplings (RDCs) for natural abundance lipid samples to obtain segmental SCH

5 Since the natural abundance of (13)C is around 1.1%, these satelli

6 f DA1 enhances leaf size in a broad range of natural accessions of this species, indicating a highly

7 INTERPRETATION: For most sudden natural adult deaths investigated by HM Coroners, PMCTA

8 tal model which incorporates genetic effect, natural aging and prolonged oral environmental toxicity

9 cagonal quasicrystals similar to decagonite, natural Al71Ni24Fe5.

10 After exposure to the natural allergen papain, mice selectively lacking the mi

11 ategy that incorporates a photoreactive, non-natural amino acid, p-benzoyl-l-phenylalanine, into vari

12 Only natural amino acids were used as probes, and thus possib

13 tanding the interactions of filoviruses with natural and accidental hosts and for identification of f

14 his has also fuelled the hypothesis that the natural and ancient origin of organohalogens could have

15 chness were not detectably different between natural and anthropogenic landscapes, but community phen

16 r understand the relative influence of these natural and anthropogenic processes.

17 ntraplate earthquake localization, with both natural and induced seismicity generally clustered in di

18 Screening of a 50000-member library of natural and synthetic compounds for sensitizers of RCC c

19 ctions between cells and biointerfaces, both natural and synthetic.

20 Vicinal stereocenters are found in many natural and unnatural compounds.

21 pal damage, and they have been proposed as a natural animal model for human epilepsy.

22 ore, EAV persistence provides a powerful new natural animal model to study RNA virus persistence in t

23 Natural anion channelrhodopsins (ACRs) discovered in the

24 architectures, and specific modification of natural antibodies has proven quite challenging.

25 ndescribed polyketides from P. malabarica as natural antioxidative and anti-inflammatory functional f

26 a promising biofilter capable of protecting natural aquafers from pathogens.

27 in pollinators attenuates the resistance of natural areas and agro-environments to disturbances.

28 uctive success in urban compared to adjacent natural areas.

29 asing efforts to use ingredients that are as natural as possible in the formulation of innovative pro

30 ng follicular and marginal zone B cells with natural autoreactivity.

31 d find that habitat fragmentation owing to a natural barrier has resulted in strong genetic division

32 ing the chemical diversity of TNA beyond the natural bases would enable the development of functional

33 l, improved social interaction, and improved natural behaviors such as nesting and marble burying as

34 form the key structural moieties of numerous natural biologically active compounds.

35 The olfactory system is a natural biosensor since its peripheral olfactory sensory

36 by quantum theory of atoms in molecules and natural bond orbital analysis.

37 Here, we show that natural C. elegans isolates differ in nictation.

38 ms, we contend that truncated power laws are natural candidates.

39 properties license CD26(high) T cells with a natural capacity to traffic to, regress and survive in s

40 arge-scale industrial applications utilizing natural carbohydrate polymers is rooted in the fact that

41 s studies have examined cue combination with natural categories (e.g., phonemes), providing qualitati

42 y to NMDG(+) but also to spermidine, a large natural cation involved in ion channel modulation, revea

43 ought is a significantly better indicator of natural co-occurrence than measures of functional trait

44 color of the calyces, and have potential as natural colorants for food applications.

45 could be efficiently used for extraction of natural colours for the food industry.

46 y dominated by a small elite, and similarly, natural communities are typically dominated by a small f

47 nt driver of biodiversity and coexistence in natural communities.

48 Here we demonstrate enhanced natural community APase activity following iron amendmen

49 e interesting, because they demonstrate that natural computing can potentially support long and compl

50 edation events to individual behaviour under natural conditions is challenging and there is currently

51 is investigation of neural activation during natural, connected speech production in children who stu

52 Describing the natural course of neovascular age-related macular degene

53 dequate to evaluate structural integrity and natural cracks.

54 We found that pretreatment of cells with a natural disaccharide trehalose, a known autophagy enhanc

55 n may prevent cognitive impairment following natural disaster.

56 Natural dissolved organic matter (DOM) affects mercury (

57 Although the natural distribution of reptarenaviruses has yet to be d

58 we introduce a new platform, the C. elegans Natural Diversity Resource (CeNDR) to enable statistical

59 This natural dye is of insect origin and should not be presen

60 nships between multiple species in intricate natural ecological networks.

61 metagenomics and virus-host interactions in natural ecosystems.

62 ackground, to contrasting conditions in semi-natural enclosures.

63 mbionts provided protection against the same natural enemy, the level of protection corresponded to t

64 en chemical reactions critically affects our natural environment and the synthesis of new materials.

65 ure release of a gene drive construct to the natural environment could damage an ecosystem irreversib

66 iofilm formation is severely hampered in the natural environment where most plastic debris accumulate

67 ro culture of neurons deprives them of their natural environment.

68 when placed into conditions that mimic their natural environment.

69 Natural environmental abundances are much lower, therefo

70 s, such as temperature, that are inherent in natural eruptions.

71 Furthermore, the mechanisms of natural evolution leading to improved or novel substrate

72 To overcome this barrier, we studied a natural experiment involving genetically inherited trait

73 reating the mouse's visual experience during natural exploratory behaviour.

74 esence of high aerodynamic resistance in the natural field and lower canopy temperature of Takanari t

75 ison is orders of magnitude more potent than natural flavonoids at protecting neural cells against ox

76 Natural flavonoids exert innumerable pharmacological eff

77 d in the biomedical sciences to the study of natural flocculated SPM filling both this spatial and di

78 The study of fiber clustering of natural flocs could be useful for improving fabrication

79 We mimicked natural fluctuations in light over a diurnal period to e

80 correct common refractive errors and provide natural focus cues by dynamically updating the system ba

81 observations, and conversion of mid-latitude natural forests to cropland and pastures is accompanied

82 the determination of inorganic As species in natural fresh water.

83 Natural freshwater systems have been severely affected b

84 The benefits and impacts of unconventional natural gas development are realized at different spatia

85 of abundant conventional and unconventional natural gas reserves have revitalized strong interest in

86 o been taken, which rely on screening broad, natural genetic diversity for metabolic diversity.

87 m-specific genes can evolve rapidly and that natural genetic variation may have led to a SLO3 variant

88 st contend with substantial inter-individual natural genetic variation.

89 dies of glycosylated insulin analogues, this natural glycosylation may provide important insights int

90 When challenged with a feed of natural groundwater containing various competing electro

91 In the natural habitat and low-pH environment of toxin-secretin

92 f selected species were collected from their natural habitats and analysed.

93 and carbon storage suggest that safeguarding natural habitats for biodiversity protection and carbon

94 ed powerful secondary 'cascading' effects on natural habitats located >1.3 km away.

95 griculture being not much lower than that in natural habitats.

96 HRB, and describe potential implications for natural halogen and carbon cycles.

97 eat-tolerant corals growing in habitats with natural high heat extremes.

98 proliferation-inducing ligand" (APRIL) is a natural high-affinity ligand for BCMA and transmembrane

99 spontaneously within 5 years in adults, the natural history and predictors of resolution in children

100 H) is a heterogeneous condition with varying natural history and therapeutic response.

101 Two natural history cohorts were studied including 168 longi

102 this study was to prospectively evaluate the natural history of a population with LAR, the potential

103 knowledge about the factors that impact the natural history of asthma.

104 The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regime

105 ailable clinical information to document the natural history of BHFS.

106 The natural history of PDGFRA- and PDGFRB-rearranged neoplas

107 We used the model to infer differences in natural history of TB and in future projections of TB.

108 investigated the impact of iNKT cells in the natural history of the disease in the Emu-Tcl1 (Tcl1) CL

109 eter as part of the multicenter, prospective Natural History of the Progression of Atrophy Secondary

110 5 years from symptom onset, enrolled in the Natural History Project of the Dystonia Coalition, were

111 without HIV infection participating in HSV-2 natural history studies (University of Washington Virolo

112 ned immunodeficiency (SCID) to a prospective natural history study.

113 ChHV5 replication in cells derived from its natural host and may be crucial not only to better under

114 portance of these findings translated to the natural host, where the AddAB system was found to be req

115 Natural hybridization, which can be involved in local ad

116 Based on the observation of natural hydrothermal pyrites, As(-I) is usually assigned

117 ivity was independent of IL-26, because both natural IL-26 released by Th17 clones and rhIL-26 lacked

118 We sorted a large collection of natural image backgrounds into multidimensional histogra

119 be substantial effects on chronic pathology, natural immunity, vaccine development strategies, immune

120 ivity towards small substrates including the natural indole-3-acetic acid, and the synthetic auxin 2,

121 Natural infection and vaccination also induced serum-neu

122 (bnAbs) to HIV envelope (Env) develop during natural infection can help guide the rational design of

123 is unclear, although as IgG2a is induced by natural infection, it is assumed this isotype is importa

124 itopes on the dimerized form of LukAB during natural infection.

125 In most natural infections or after recovery, small numbers of L

126 evolution, beyond those already observed in natural infections, and may help predict its future dire

127 nd intrinsic motivation, social learning and natural interaction with peers, and embodiment.

128 f columnar K(+)-water wires observed for the natural KcsA channel.

129 lymphocytosis marked by massive expansion of natural killer (NK) and T cell compartments.

130 Donor natural killer (NK) cell alloreactivity in HCT can contr

131 Mouse liver contains two natural killer (NK) cell populations, one of which recir

132 Maturation of human natural killer (NK) cells as defined by accumulation of

133 To test the hypothesis that natural killer (NK) cells can decrease the risk of leuke

134 Natural killer (NK) cells localize in the microcirculati

135 a higher percentage of effector T cells and natural killer (NK) cells present in the lung.

136 ls, but less is known about their effects on natural killer (NK) cells, which help control metastasis

137 latory receptor expressed on activated T and natural killer (NK) cells.

138 but leaves the cells vulnerable to lysis by natural killer (NK) cells.

139 ant role in antiviral immunity by regulating natural killer and CD8(+) T cells, epigenetic downregula

140 Specific natural killer cell depletion 24 hours pre-acute myocard

141 precursor) and lineage (B cell, T cell, and natural killer cell).

142 Natural killer cells showed reduced T-bet expression at

143 ype CD4 T cells, reduced T-bet expression by natural killer cells, and expansion of blood monocytes w

144 associated with reduced numbers of invariant natural killer T and Treg cells that likely contribute t

145 Invariant natural killer T cells (iNKT cells) are innate-like lymp

146 e T cell antigen receptor (TCR) expressed by natural killer T cells (NKT cells) and the antigen-prese

147 the current study is to explore the role of natural killer T cells in impaired liver regeneration.

148 It has been shown that the proportion of natural killer T cells is markedly elevated during liver

149 stigated the coordinated activation of T and natural killier (NK) cells in addition to gemcitabine ch

150 asm, to animals looking for food or mates in natural landscapes, to rescuers during search and rescue

151 NM were spiked into DI H2O and synthetic and natural leachates.

152 an optimal color constancy solution to most natural light environments.

153 noscale imaging of myelinated axons in their natural living state.

154 ted genetic risk score was calculated by the natural log of the odds ratio multiplied by the number o

155 the decay of platelet mRNAs is slowed by the natural loss of the mRNA surveillance and ribosome rescu

156 rtainty of the classification and provides a natural measure of precision, both at individual partiti

157 ion person-years, 2041 women reported having natural menopause before the age of 45 y.

158 We propose the use of natural microbial communities for CCS monitoring and CO2

159 a mouse gut colonization model in which the natural microbiota is unperturbed, the disruption of glp

160 textures closely resemble those observed in natural microcrystalline inclusions.

161 plex networks; however, our understanding of natural microecologies is limited.

162 the course of nonpathogenic SIV infection in natural nonhuman primate hosts.

163 h therapy makes a significant improvement in natural nutraceuticals.

164 g artificially colored objects compared with natural objects, suggesting that industrialization promo

165 Europe from Asia has been eventful, as these natural obstacles were crossed westward by multiple wave

166 new hydrogen self-diffusion coefficients in natural olivine single crystals that were determined at

167 netically isolating synthetic organisms from natural organisms and viruses.

168 we integrate current knowledge regarding the natural origin and occurrence of industrially important

169 he midwife toad, Alytes obstetricans in semi-natural outdoor mesocosms originating from geographicall

170 created both biologically and abiotically at natural oxic/anoxic interfaces.

171 s show that oxygen vacancy rows are not only natural oxygen diffusion channels, but also preferred si

172 eactive memory B cell antibodies elicited by natural Pf exposure that potently inhibited parasite tra

173 ic processes is essential to understand many natural phenomena, particularly in biology, including th

174 Natural, physiological scenarios that activate these sta

175 igh anthocyanin content; it can be used as a natural pigment, also adding potential health benefits.

176 s (AuNPs) synthesized in situ in alginate, a natural polysaccharide.

177 le to measure fitness for all genotypes in a natural population.

178 es are present in 18-26%, 9-14% and <1.5% of natural populations at 150 m with >/=85% identity to str

179 ection, shaping the adaptive trajectories of natural populations in complex ways, and deserves furthe

180 g only, the amount of observed inbreeding in natural populations is generally low compared with that

181 ble temperatures as well as physical flux in natural populations, which will affect the ecology and e

182 enhance our understanding of the dynamics of natural populations.

183 ges in larval dragonfly communities across a natural predation gradient we demonstrate that variation

184 tastatic process, as opposed to representing natural primary tumor progression.

185 ned observations lead us to propose that the natural process of brain masculinization puts males at r

186 dependent of ROS generation, and unlike many natural product based HDAC inhibitors, 4a was found to b

187 that showcase both the chemical diversity in natural product biosynthesis as well as the parallels wi

188 of complex biological processes ranging from natural product biosynthesis through to the mammalian vi

189 struction of the potent antibacterial marine natural product bromophycoic acid E scaffold.

190 We found that the natural product caffeic acid phenethyl ester (CAPE) disr

191 represents an intriguing mechanism by which natural product diversity arises.

192 he first total syntheses of members of these natural product families are reported as their racemates

193 synthetic efforts toward each member of the natural product family, including biomimetic, semisynthe

194 ed synthesis of the core of the norditerpene natural product ineleganolide.

195 isomeric methylene homologues (including the natural product itself) were obtained using a one-pot mi

196 , the incorrect structural assignment of the natural product serratin was identified.

197 shares a binding site with other imide-based natural product translation inhibitors, CL engages in a

198 lf-renewal or differentiation has arrived at natural product-based agents as an important class of mo

199 Several natural product-relevant motifs are accessed in enantioe

200 calable synthesis of a polycyclic brominated natural product.

201 of 1 do not match the data reported for the natural product.

202 rusion-based biomimetic spinning devices.The natural production of silks remains elusive and subseque

203 applied to the late-stage diversification of natural products and a marketed drug under mild conditio

204 X-X bonds are found in all major classes of natural products and often impart significant biological

205 and yet are present in a number of bioactive natural products and synthetic pharmaceuticals.

206 , and scalable syntheses of the halichondrin natural products are reported.

207 7-methoxy derivatives, and the O-prenylated natural products boropinols A and C.

208 Halogenated natural products constitute diverse and promising feedst

209 any biologically and pharmaceutically active natural products contain chlorine and thus, an understan

210 ducts was designed, aiming to access several natural products from a common synthetic intermediate re

211 Numerous classes of natural products have been subjected to these studies of

212 These natural products have in common an E,Z-configured conjug

213 Natural products have served as powerful therapeutics ag

214 , late stage C-7 hydroxylation provides both natural products in six and seven operations.

215 ive conversion of a single hydroxyl group in natural products into a ketone would enable the selectiv

216 We highlight several plant natural products that are either in the clinic or curren

217 lines are an interesting class of oligomeric natural products that consist of multiple cyclotryptamin

218 ward the oridamycin and xiamycin families of natural products was designed, aiming to access several

219 ing new and existing laboratory syntheses of natural products with findings of the compounds' unique

220 iplinary impacts for catalytic remodeling of natural products, including contributions to SAR develop

221 s are a common structural motif in bioactive natural products, therapeutic agents, and molecular cata

222 roxyl group among many in unprotected polyol natural products.

223 to the engineered biosynthesis of prenylated natural products.

224 thetic pathways of many structurally complex natural products.

225 carbon cross-link in the streptide family of natural products.

226 core structure of a wide array of bioactive natural products.

227 es by small molecules, peptide mimetics, and natural products.

228 ults suggest that (i) many designed, or even natural, protein cages may not be regular in the presenc

229 Natural proteins do not provide a useful guide: Peptide

230 ological matrices and its interaction with a natural receptor molecule has tremendous importance in c

231 Using either constructed or natural reefs to manipulate habitat availability, we doc

232 t to neighbouring artificial reefs or nearby natural reefs.

233 udies have failed to investigate the role of natural regulatory T cells (nTregs) on the mitigation of

234 Natural reinforcers, like food and sex, activate this pa

235 resent in soil can play an important role in natural remediation mechanisms of carbamates.

236 The therapeutic implications of these natural, remote-loaded nanoformulations are studied both

237 The natural reservoir of MARV is the Egyptian rousette bat (

238 xydammarenone and abietic acid as well as of natural resin varnishes made from dammar and colophony.

239 The anticipated feed streams are natural river and seawater, both of which contain not on

240 ng the importance of the preservation of the natural Sardinian ecosystems for endangered species and

241 ace fluids from scCO2 -water separators at a natural scCO2 reservoir at McElmo Dome, Colorado for ana

242 ht intensities (photons s(-1) mum(-2) ) in a natural scene vary over several orders of magnitude from

243 ral networks (DCNNs) and panoramic videos of natural scenes, viewed immersively through a head-mounte

244 ion and gaze, while monkeys watched video of natural scenes.

245 paper, we dissolve (13)C-labeled calcites in natural seawater.

246 We also present evidence that the targets of natural selection change over time, as epistasis and his

247 Here, we explore the role of natural selection in shaping the processes that underlie

248 ffer opportunities to observe the effects of natural selection in wild populations.

249 However, natural selection typically generates adaptation in resp

250 t evolutionary mechanisms, such as mutation, natural selection, and genetic drift, and also the inter

251 such as Neanderthals, and the ways in which natural selection, in its various guises, has shaped gen

252 As a source of genetic diversity and natural selection, mutations are beneficial for evolutio

253 ave profound effects on their hosts, driving natural selection, promoting speciation and determining

254 l to the evolution of genomes in response to natural selection.

255 s to their local environments as a result of natural selection.

256 ene providing a function that is targeted by natural selection.

257 a less-studied fibre reinforcement, that of natural silk.

258 Natural silks are considered increasingly for medical ap

259 Natural sounds such as wind or rain, are characterized b

260 Strawberry is a major natural source of bioactive compounds.

261 e number of bioactive peptides isolated from natural sources are known to play important physiologica

262 Hence, the limited availability from natural sources, coupled with an estimated demand of one

263 suggests promise for the use of fNIRS during natural speech production in future research with typica

264 onstrate the effects of modifying the TFS in natural speech sentences on both speech recognition and

265 mental validation, our results indicate that natural spinning is achieved, not by extruding the feeds

266 e paracrine and biointerfacing activities of natural stem cells in therapeutic cardiac regeneration.

267 Here we analyse responses of V2 neurons to natural stimuli and find three organizing principles.

268 TNF-alpha after treatment with DMXAA or the natural STING ligand cyclic GMP-AMP (cGAMP).

269 On the other hand, this natural stochasticity can be valuable for hardware secur

270 ental support of critical slowing down along natural stress gradients in tidal marsh ecosystems.

271 Moreover, as interactions with natural stressors may cause underestimates of the impact

272 measured in pure water exposed to simulated natural sunlight at a constant irradiance value (500 W m

273 del shows that adaptation in a coupled human-natural system can trigger self-organized criticality (S

274 ed organic molecules, are absent from inland natural systems and these compounds could therefore play

275 is dynamics are the typical response of many natural systems to a periodic external forcing, like e.g

276 In natural systems, biodiversity changes are often part of

277 ules that underlie ecological rates in other natural systems.

278 metal oxide materials, which are abundant in natural systems.

279 anganates) often control trace metal fate in natural systems.

280 arly at the sediment-water interface in many natural systems.

281 ut nervous system function in the context of natural tasks.

282 of Mmp9 caused improper processing of DSP in natural teeth.

283 m tropical forest soils, the world's largest natural terrestrial N2O source.

284 Recently, populations of natural Th17 and Th1 cells (nTh17 and nTh1) with innate-

285 This entails dividing the structure into 'natural tiles' or Voronoi polyhedra that are metastable

286 s, it is crucial to identify their long-term natural trends, ecological thresholds, and responses to

287 ntrations, are considerably less stable than natural variants under near-physiological ionic conditio

288 ions along the length of DYRK1A with that of natural variants, as found in the ExAC database, confirm

289 -reverse genetic strategy revealed the broad natural variation in low-water-potential-induced ABA acc

290 er different types of stress indicating that natural variation in repeat numbers may optimize the cha

291 as other model organisms to investigate how natural variation shapes traits, especially through the

292 Here, we analysed natural variations in PfHRP2 and PfHRP3 sequences from I

293 es but diverge in their responses under more natural viewing conditions.

294 Additionally, rather than relying on natural viral properties, efforts are underway to engine

295 ecruited prefrontal control regions, whereas natural, voluntary switching did not.

296 Three natural water samples, a fresh leaf leachate and two hum

297 osic fibers is desirable for purification of natural water.

298 The resulting in-line acidification of natural waters with millimolar sodium chloride level (fr

299 opical wetlands contribute 60%-80% of global natural wetland CH4 emissions.

300 The pristine, natural wood is cut along the transverse direction and t