ライフサイエンスコーパス: natural host

1 er SIVrcm Nef can antagonize tetherin of its natural host.

2 virulence for this Mycoplasma species in its natural host.

3 ew functions involved in colonization of its natural host.

4 erty, which is critical for infection of the natural host.

5 1 is a virulence determinant for ORFV in the natural host.

6 2 is nonessential for virus virulence in the natural host.

7 viruses and their disease potential in their natural host.

8 is not essential for virus virulence in the natural host.

9 volved from low to high conformations in the natural host.

10 r understanding H. pylori persistence in its natural host.

11 of the lethal neurovirulent phenotype in the natural host.

12 n by mouse mammary tumor virus (MMTV) in its natural host.

13 ect important target cell populations of its natural host.

14 me of a pathogenic bacteria recovered from a natural host.

15 es a dicistrovirus that is infectious in its natural host.

16 f such scrapie-associated fragments within a natural host.

17 lent CSFV strain Brescia in infection of the natural host.

18 f PKR in controlling FMDV replication in the natural host.

19 enance of nonpathogenic SIV infection in its natural host.

20 RV) persists predominantly in B cells of its natural host.

21 jejuni employs to achieve commensalism in a natural host.

22 or described, linkingS. suisto pigs as their natural host.

23 ions with a highly pathogenic viruses in the natural host.

24 nd immunity of this novel hepacivirus in its natural host.

25 esponse that developed during infection of a natural host.

26 ntly less able to cause acute disease in the natural host.

27 iral and host determinants of virulence in a natural host.

28 lly known to cause obvious symptoms in their natural hosts.

29 tible species, but is absent in SIV-infected natural hosts.

30 d bird species, which are believed to act as natural hosts.

31 chronic immune activation observed in these natural hosts.

32 ed to the restriction of SIV pathogenesis in natural hosts.

33 nfection pattern similar to SIV infection in natural hosts.

34 in the immune response against Y. pestis in natural hosts.

35 appear to contribute to viral containment in natural hosts.

36 del to study hepacivirus infections in their natural hosts.

37 ed immunodeficiency syndrome (AIDS) in their natural hosts.

38 on during acute and chronic SIV infection in natural hosts.

39 s precious little known about AAV biology in natural hosts.

40 outcomes in SIV infection of natural vs non-natural hosts.

41 ropic DNA viruses that cause tumors in their natural hosts.

42 e regarding the effects of serial passage in natural hosts.

43 e infection of cell lines derived from their natural hosts.

44 ia of the peripheral nervous system in their natural hosts.

45 host range susceptibility, and virulence in natural hosts.

46 ity of primate lentiviruses to spread within natural hosts.

47 irect the virus to different cell targets in natural hosts.

48 eptor CCR5 on CD4(+) T cells of SM and other natural hosts.

49 than the parental VSIV-GI virus in swine, a natural host (26).

50 of FQ-resistant Campylobacter in chicken (a natural host and a major reservoir for C. jejuni) in the

51 navirus, use aminopeptidase N (APN) of their natural host and feline APN (fAPN) as receptors.

52 ogical activity of cyhv3Il10 on cells of its natural host and indicates that cyhv3Il10 is a true vira

53 ChHV5 replication in cells derived from its natural host and may be crucial not only to better under

54 tial invertebrate hosts, including one known natural host and other potential hosts collected from th

55 s virus (MHV), causes acute hepatitis in its natural host and provides a useful model for understandi

56 class I diversity in wild mallard ducks, the natural host and reservoir of influenza A viruses.

57 eded to study gonococcal pathogenesis in the natural host and to classify strains from direct clinica

58 were developed to study sheep scrapie in the natural host and to investigate potential cofactors in t

59 medical importance and across humans, other natural hosts and laboratory animals.

60 onses against pathogenic poxviruses in their natural hosts and provide further support for the use of

61 Overall, Escherichia coli survival in natural hosts and reservoirs is expected to rely on the

62 y symbiotic relationship between HBV and its natural host, and highlight the plasticity of the fetal

63 and EV are important for OPV pathogenesis in natural hosts, and whether a system based on F13L orthol

64 specifically induced during infection of the natural host animal by using an in vivo expression techn

65 cells can cause papillomatous growths in the natural host animal.

66 ned studying FHA using B. bronchiseptica and natural-host animal models should apply to B. pertussis

67 in pathogenesis using B. bronchiseptica and natural-host animal models.

68 Thus, adaptive immune responses in natural hosts appear to be less critical for viral conta

69 Thus, the limited SIV MTIT in natural hosts appears to be due to low target cell avail

70 patterns of humoral immune responses in the natural host are therefore more similar to those observe

71 These data provide insights into how natural hosts are able to maintain high levels of plasma

72 ere we show that (i) acute SIV infections of natural hosts are associated with a rapid and robust typ

73 Identifying how natural hosts avoid immunodeficiency can elucidate key m

74 rogram during pathogenesis compared with the natural host barley despite ~200 million years of reprod

75 ntrol of viral replication and spread in the natural host, but the specific contributions of MDA5 sig

76 ntral nervous system is surprisingly rare in natural hosts, but can be fatal.

77 STAT1 are required to sustain virulence in a natural host by controlling the inflammatory response ag

78 an immunodeficiency virus (SIV) infection in natural hosts by inoculating Caribbean AGMs with their s

79 ruses tend to cause limited disease in their natural hosts, CAdV A is unusual in that it may cause hi

80 inst an orthopoxvirus (OPV) infection in its natural host can develop in the absence of CD4(+) T cell

81 Stat3 pathway modulating immune cells of its natural host, carp.

82 evidence of an encephalitic DNA virus in its natural host causing increased MMP activity in brains.

83 are relevant to pathogenesis were tested in natural host cell cultures, a model of the human airway

84 in limiting archetype BKPyV replication in a natural host cell model of infection.

85 d the mechanisms by which HCV spreads in its natural host cell population.

86 s with true virus particles assembled in the natural host cell to assess L2's role in the viral infec

87 Infections of human keratinocytes, a natural host cell type for HPVs, were assessed visually

88 the high-risk HPV type 31 (HPV31) enters its natural host cell type via caveola-dependent endocytosis

89 P27 in the interaction of M. bovis with its natural host cell, the bovine macrophage.

90 re as a negative control) and macrophages (a natural host cell, used here as a positive control).

91 l proximal tubule epithelial (RPTE) cells, a natural host cell.

92 al tubule epithelial (RPTE) cells, which are natural host cells for BKV.

93 f mammalian viruses to suppress silencing in natural host cells have remained controversial.

94 ches to identify human dermal fibroblasts as natural host cells that support productive MCPyV infecti

95 ere evaluated for their pathogenicity in the natural host, chickens.

96 icantly fewer severe tracheal lesions in the natural host compared to virulent M. gallisepticum R(low

97 on within the lymph node germinal centers of natural hosts contributing to sustained immune competenc

98 s of Antimicrobial Peptides (SMAMPs) imitate natural host-defense peptides, a vital component of the

99 ensis infection of tick-derived cells from a natural host, Dermacentor variabilis.

100 w that plasmacytoid dendritic cells (pDC) of natural hosts display reduced CD4 and/or CCR5 expression

101 Unlike AIDS-susceptible rhesus macaques, natural hosts do not progress to AIDS and resolve immune

102 (SIVs) are generally nonpathogenic in their natural hosts, dramatic increases in pathogenicity may o

103 ce of differential regulation of porins in a natural host environment.

104 Despite this, natural hosts experience a level of viremia similar to h

105 SM and other natural hosts express very low levels of CCR5 on CD4(+)

106 e aggressive leukaemias and lymphomas in non-natural hosts, expresses seven small nuclear uracil-rich

107 Rodents are a natural host for asexually replicating forms, whereas ca

108 not affect disease progression in swine, the natural host for ASFV.

109 5 commonly infects dogs, dogs may not be the natural host for PIV5.

110 CD4(+) TCM cells of sooty mangabeys (SMs), a natural host for SIV in which infection is nonpathogenic

111 nulin (BgGRN)] from the snail B. glabrata, a natural host for the human blood fluke Schistosoma manso

112 , we treated SIV-infected sooty mangabeys, a natural host for the infection, with a potent antiretrov

113 simian arteriviruses and define baboons as a natural host for these viruses.

114 As a major natural host for Toxoplasma gondii, the mouse is widely

115 The mouse is a natural host for Trichinella spiralis, a worm that estab

116 otective in studies of horses, an incidental natural host for WNV.

117 ied AAV8 vector infusion in rhesus macaques, natural hosts for AAV8.

118 Baboons (Papio anubis) are natural hosts for Entamoeba histolytica; naturally infec

119 ally in lymphocytes and monocytic cells, the natural hosts for HIV-1 infection.

120 any species of African nonhuman primates are natural hosts for individual strains of simian immunodef

121 Although the natural hosts for L. pneumophila are free-living protozo

122 The importance of bats as natural hosts for several important viral zoonoses, incl

123 Natural hosts for simian immunodeficiency virus (SIV) ca

124 mechanisms underlying the AIDS resistance of natural hosts for simian immunodeficiency virus (SIV) re

125 mmunodeficiency virus (HIV)-infected humans, natural hosts for simian immunodeficiency virus (SIV) ve

126 Nonhuman primate natural hosts for simian immunodeficiency viruses (SIV)

127 Here we report that natural hosts for SIV infection express remarkably low l

128 comparative studies between non-natural and natural hosts for SIV, in which SIV infection results in

129 n only if a prion disease is engendered in a natural host from an infectious prion produced in vitro.

130 nd not to be stably maintained outside their natural host genus.

131 mon characteristics with other synthetic and natural host-guest and molecular recognition processes i

132 ymphomagenesis during chronic infection in a natural host has been limited by the exquisite species s

133 nvolves a variety of strains of EEHV1, whose natural host has been unclear.

134 ogical activity of cyhv3Il10 on cells of its natural host have not been performed.

135 It is known that despite high viral loads, natural hosts have a low frequency of CD4(+) cells expre

136 These studies indicate that natural hosts have developed mechanisms in addition to c

137 Natural hosts have very low levels of the SIV entry core

138 es cellular damage, and persists in its only natural host (humans) are unique and are not fully under

139 nt for heme, which it acquires from its only natural host, humans.

140 ariants were expressed during infection of a natural host, (ii) the structural variation observed in

141 ssociation of MP-derived tubules and PD in a natural host, improving our fundamental understanding of

142 h the pathogenic SIV infection, while in the natural hosts, in which SIV is nonpathogenic, B cells ra

143 our data suggest a unifying model whereby in natural hosts, in which the CCR5 expression level is low

144 f lentiviral infections of seemingly adapted natural hosts, including mechanisms of host control and

145 ess of A. pleuropneumoniae was assessed in a natural host infection model.

146 evolution of virus and host effectors in the natural host, influenza virus evasion of IFITM3 restrict

147 ure, which are representative of foreign and natural host initial target cells of B virus.

148 mmunodeficiency virus (SIV) infection in its natural host is characterized by a lack of increased imm

149 3A in virus growth and virulence within the natural host is not well understood.

150 ent for Argentine hemorrhagic fever, and its natural host is the New World rodent Calomys musculinus.

151 infection dynamics at the target tissues of natural hosts is central to understanding the mechanisms

152 an immunodeficiency virus (SIV) infection of natural hosts is characterized by nonpathogenic chronic

153 an immunodeficiency virus (SIV) infection of natural hosts is nonpathogenic despite high levels of vi

154 infection in African nonhuman primate (NHP) natural hosts is usually nonpathogenic, despite high lev

155 H7N9) influenza virus infection of chickens (natural hosts) is asymptomatic and that it generates a h

156 ne cells is important for nonpathogenesis of natural hosts, it is possibly not due to its role as a c

157 While it is still unknown how natural hosts like AGM can cope with this lentivirus inf

158 These observations demonstrate that natural hosts like SIV-infected vervet AGM develop SIV-s

159 with that of the parental wild-type MV in a natural host, Macaca mulatta.

160 These natural hosts maintain high SIV viral loads, but avoid i

161 lity that CXCR6-directed tropism in CCR5-low natural hosts may alter CD4(+) T cell subset targeting c

162 ed in HIV-infected subjects, suggesting that natural hosts may be more appropriate for modeling the i

163 ic stimulation of pDCs by SIV and HIV in non-natural hosts may drive the unrelenting immune system ac

164 n in contributing to the mechanisms ensuring natural host-microorganism communication is in need of f

165 ice with LDV and FV provides a well-defined, natural host model for such studies.

166 ocular herpes in a physiologically relevant natural host model.

167 emphasizes the value of our model as a virus-natural-host model to study ocular herpesvirus infection

168 d, in part due to the lack of adequate virus-natural-host models in which to study the cellular and v

169 hat the RVT protein purified from one of its natural hosts, Neurospora crassa, exists in a multimeric

170 Ducks are the natural host of avian influenza A viruses and display fe

171 es, and when we infected domestic swine, the natural host of CSFV host, we observed that the virus wa

172 d in some stage of chronic infections in the natural host of horses, or the QS genes may be remnants

173 The natural host of influenza A viruses (IAVs) are aquatic b

174 TMs are involved in protection in ducks, the natural host of influenza virus.

175 Drosophila melanogaster is a natural host of parasitic wasps of the genus Leptopilina

176 ssibility that dogs (or pigs) may not be the natural host of PIV5.

177 antiviral response in primary cells from the natural host of PRV but is not necessary in nonnatural-h

178 esponse during in vivo infection in RMs, the natural host of RRV.

179 Sooty mangabeys are a natural host of simian immunodeficiency virus (SIV) that

180 reen monkeys (AGMs; genus Chlorocebus) are a natural host of simian immunodeficiency virus (SIVAGM).

181 African green monkeys (AGMs) are a natural host of SIV that do not develop simian AIDS.

182 ile serology-based approach to determine the natural host of the only known nonprimate hepacivirus (N

183 simian arteriviruses, identify baboons as a natural host of these viruses, and provide further evide

184 erent serotypes in sheep and cattle, the two natural hosts of BTV.

185 The natural hosts of hantaviruses include rodents, shrews, m

186 type 1 (HIV-1) infections, but they are not natural hosts of HIV-1 or any simian immunodeficiency vi

187 (Anas platyrhynchos) is one of the principal natural hosts of influenza A viruses.

188 Wild waterfowl, including ducks, are natural hosts of influenza A viruses.

189 Adult pigs, the natural hosts of PRV, survive infection with only mild r

190 ty in most nonhuman primate species that are natural hosts of simian immunodeficiency virus (SIV) inf

191 M) and sooty mangabeys (SM) are well-studied natural hosts of simian immunodeficiency virus (SIV) tha

192 African green monkeys (AGM) are natural hosts of simian immunodeficiency virus (SIV), an

193 African green monkeys (AGMs) are natural hosts of simian immunodeficiency virus (SIVAGM).

194 Natural hosts of SIV do not progress to AIDS, in stark c

195 Natural hosts of SIV express very low levels of the cano

196 e course is observed during the infection of natural hosts of SIV infection, such as sooty mangabeys

197 and absence of lymph node immunopathology in natural hosts of SIV infection.

198 rties of milk of SIV-infected and uninfected natural hosts of SIV, African green monkeys (AGMs), to t

199 African green monkeys (AGM) are natural hosts of SIV, and infection in these animals gen

200 These natural hosts of SIV, like sooty mangabeys, maintain hig

201 Natural hosts of SIV, such as sooty mangabeys, sustain h

202 he rarity of postnatal virus transmission in natural hosts of SIV.

203 monkeys share immunophenotypic features with natural hosts of SIV; that is, low levels of CD4+ T cell

204 t the ADO pathway may be involved in sparing natural hosts of SIVs from developing SIV-related gut dy

205 t preventing cross-species transmission from natural hosts of SIVs to humans in areas of endemicity.

206 lack of SIV transmission to the offspring in natural hosts of SIVs.

207 n the lack of breast-feeding transmission in natural hosts of SIVs.

208 could reflect the possibility that boas are natural hosts of these viruses in the wild.

209 ruses in foreign and sometimes even in their natural hosts often stems from the action of potent host

210 ong-lasting bacteremia in reservoir-adapted (natural host or passive carrier of a microorganism) and

211 e transfer and usage of amino acids from the natural host organism Acanthamoeba castellanii to Legion

212 acilitates investigation of noroviruses in a natural host organism and the identification of viral an

213 thogen effector proteins in experimental and natural host organisms.

214 Analysis of natural host-parasite relationships reveals the evolutio

215 Using the natural host-parasite system Daphnia magna-Pasteuria ram

216 However, knowledge obtained from natural host-parasitoid systems on such trade-offs is st

217 romelia virus {ECTV}]) despite the lack of a natural host-pathogen relationship with either of these

218 the natural host sooty mangabey and the non-natural host pig-tailed macaque.

219 nce in the mouse model; however, its role in natural hosts-pigs, humans, or birds-remains largely unk

220 Using reciprocal transplants onto natural host plants across the UK range, we demonstrate

221 ance: An understanding of viral evolution in natural host populations is a fundamental goal of virolo

222 ns achieved aggregation levels comparable to natural host populations.

223 nance of genetic variation for resistance in natural host populations.

224 ogens to influence evolutionary processes in natural host populations.

225 MAV-1 produces viral encephalitis in its natural host, providing a good model for studying factor

226 odel with which to study determinants of the natural host range of this virus.

227 Their natural host ranges are limited to individuals within th

228 V-B), both viruses with largely undetermined natural host ranges.

229 amics, and determinants of WNV spread in its natural hosts remain uncertain.

230 (SIVs), are virtually nonpathogenic in their natural hosts remains a fundamental mystery of modern me

231 es (RMs) but not in sooty mangabeys (SMs), a natural host, remains unclear.

232 ate for identifying biological correlates of natural host resistance to HIV-1 infection.

233 genetics to search for mechanisms underlying natural host resistance to infection and identified trig

234 varied routes of transmission from its major natural hosts, ruminant farm animals; and other aspects

235 Using mice that are natural host's of Bordetella bronchiseptica, we determin

236 ion because simian immunodeficiency virus in natural hosts seldom causes disease.

237 hich ocular herpes can be studied in a virus-natural-host setting and (ii) it reduces the number of e

238 evels of Nab might be an inherent feature of natural-host SIV infections.

239 despite being generally nonpathogenic in its natural host, SIV infection selects for Vif-resistant fo

240 ph nodes during primary SIV infection of the natural host sooty mangabey and the non-natural host pig

241 Natural host sooty mangabeys (SM) infected with simian i

242 es characterized by progression to AIDS, and natural host sooty mangabeys (SMs), a species which rema

243 Natural-host sooty mangabeys (SM) infected with simian i

244 A virus, soybean mosaic virus (SMV), and its natural host, soybean.

245 ime suggests that LBV is well adapted to its natural host species and that populations of reservoir h

246 ent of SIV-infected African green monkeys, a natural host species for SIV that does not manifest GI t

247 ic SIV infection of sooty mangabeys (SMs), a natural host species for SIV, is also associated with an

248 bsence of SIV-induced disease progression in natural host species may be partially explained by prese

249 r, the impact of ablating PrP(C) function in natural host species of prion diseases is unknown.

250 SIV infection of natural host species such as sooty mangabeys results in

251 rus (SIV), for which it is the most abundant natural host species, and of a wide range of health-rela

252 African green monkeys, one natural host species, avoid simian AIDS by creating a po

253 SIV infection of sooty mangabeys (SMs), a natural host species, does not cause AIDS despite high-l

254 nducing an AIDS-like immunodeficiency in its natural host species, the domestic cat.

255 IDS in SIV-infected sooty mangabeys (SMs), a natural host species, we performed a detailed analysis o

256 suggest a new paradigm for SIV infection of natural host species, whereby a shared outcome of virus-

257 ay be a common feature of SIV replication in natural host species, with the potential to contribute t

258 ues is not sufficient to induce AIDS in this natural host species.

259 ostnatal transmission rates observed in this natural host species.

260 an immunodeficiency virus (SIV) infection of natural-host species, such as sooty mangabeys (SMs), is

261 n maintaining nonpathogenic SIV infection in natural hosts such as sooty mangabeys (SM) remains to be

262 In addition, SIV-infected African natural hosts such as the sooty mangabeys (SM) are resis

263 Natural hosts, such as African green monkeys (AGM) and s

264 mmunodeficiency virus (SIV) infection in its natural hosts, such as African green monkeys (AGM) and s

265 e stability/incubation time correlation in a natural host system.

266 livestock, which is applicable to a range of natural host systems, including strains of bovine spongi

267 on SM CD4(+) subsets may delineate distinct natural host target cell populations capable of supporti

268 pA) direct repeat 2 Fic domain (DR2/Fic) for natural host target cells.

269 ating antiviral potency in cells relevant to natural host target tissue.

270 tive parasite biological states occur in the natural host that are not observed with in vitro cultiva

271 erfect example of virus dissemination by its natural host that may have dramatic public health conseq

272 ition, we summarize the lessons learned from natural hosts that know how to 'show AIDS the door', and

273 of the coevolution between the virus and its natural hosts that led to a nonpathogenic infection.

274 he nonprogressive nature of SIV infection in natural hosts that underlie maintained high levels of pl

275 C. jejuni during in vivo colonization of its natural host, the chicken.

276 respiratory tract both in humans and in its natural host, the dromedary camel.

277 In its natural host, the fruit compensates for the impaired mat

278 hese features with those observed in another natural host, the mandrill (MND), we conducted a cross-s

279 induces robust type I IFN production in its natural host, the mouse.

280 quite different from that in the original or natural host, the pathogen may not be suspected based on

281 n the establishment of latency by PrV in its natural host, the pig.

282 ission and serial passage of SIVsab from its natural host, the sabaeus African green monkey (AGM), to

283 oup II introns are active in bacteria, their natural hosts, they function inefficiently in eukaryotes

284 pact on the major immune cell populations in natural hosts, thus confirming the nonpathogenic nature

285 lls and limit infection of critical cells in natural hosts, thus contributing to benign outcome of in

286 ould be evaluated using clinical isolates in natural host tissue rather than lab strains of virus in

287 lection when MERS-CoV transmitted from their natural host to human; 3) Six out of nine positive selec

288 Elucidating the mechanisms that allow natural hosts to coexist with SIV without overt disease

289 Elucidating the mechanisms that allow natural hosts to coexist with SIV without overt disease

290 phenotypes during long-term colonization of natural hosts to resemble those of their hosts, providin

291 DC3000, was reported to infect not only its natural host tomato but also Arabidopsis in the laborato

292 etic variability of virus replication in the natural host under experimental conditions and no geneti

293 been postulated, it has not been tested in a natural host until recently.

294 Overall, in a natural host, we have demonstrated a link between the in

295 estigate early control of SIV replication in natural hosts, we performed a detailed characterization

296 portance of these findings translated to the natural host, where the AddAB system was found to be req

297 cient evolutionary history of their putative natural hosts, which began diversifying tens of millions

298 The SIV(+) sooty mangabey natural hosts, which do not proceed to clinical AIDS, pr

299 gate perturbations in lymphocyte dynamics in natural hosts with nonpathogenic simian immunodeficiency

300 hether coevolution between viruses and their natural host would result in the evasion of IFITM restri