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1                             As a result, there is a growing need to be able to store, update, explore, and analyze phage
2  to enable assessment of model performance, and issues that need to be addressed for an institution to adopt these interv
3 n-communicable diseases are now recognised as diseases that need to be addressed in such crises.
4 fy outstanding questions and methodological challenges that need to be addressed to advance and solidify our comprehensio
5 sentation of women in HF guidelines and HF trial leadership need to be addressed.
6 ne testing substantially reduces risk of outbreaks, but may need to be as frequent as twice weekly.
7                      It is unknown how severe visual losses need to be before changes in auditory abilities occur, or whe
8 However, to overcome the sparsity of FRET experiments, they need to be combined with computer simulations.
9                                                 The results need to be confirmed in analytical studies, in which informat
10  design) and emerging technical opportunities that we argue need to be considered to maximize the added value and long-te
11          The functional coupling between these two channels need to be considered when assessing clinical variants and th
12  domain-swapped and nondomain-swapped ASIC M2 conformations need to be considered.
13 energy dissipation, conductivity, and mass diffusivity also need to be considered.
14 ndings reveal the complexity of recruitment mechanisms that need to be coordinated in localizing an ARF GEF to an intrace
15                              Key features of GM-CSF biology need to be defined better, such as the responding and produci
16 ay open the way to more precise treatment, but more efforts need to be devoted to a better understanding of the relation
17  to find a particular level of family-wise significance may need to be established using separate permutations of the act
18                                           NCD services will need to be expanded in Kenya.
19  synergic effect on the resulting electronic band structure need to be explored in a broader material scope.
20                      Alternative tumour suppressor pathways need to be explored to treat p53- deficient tumours.
21 cations and combinations of methods may prove promising and need to be explored.
22                                        The detection assays need to be extremely sensitive and selective in small value o
23 or rapid sepsis diagnosis where minimal numbers of bacteria need to be found in a 1-10 mL blood sample.
24 echanisms with which macrophytes enhance nutrient retention need to be further understood.
25  challenging endeavor and efficient ligand-receptor systems need to be identified.
26 involved in alcohol use and novel biomarkers of alcohol use need to be identified.
27 rotubule nucleation pathways and their mode of action still need to be identified.
28                            Moving forward, prediction tools need to be incorporated in well-designed randomized controlle
29 lection on MHC genes are simultaneously being revealed that need to be incorporated into existing theory.
30                                        These novel findings need to be investigated for consistency in other studies but
31                                         Prenatal oestrogens need to be investigated, as they play a key role in synaptoge
32 gs where patient management and infection control decisions need to be made rapidly.
33                                                     Efforts need to be made to increase the perception, use, and translat
34 etroviral therapies efficiently block HIV-1 replication but need to be maintained for life.
35                                          However, this will need to be maintained or triggered more frequently in these s
36                In particular, parameters of the water model need to be modified to improve applicability of the force fie
37              Currently, all reported liquid metal batteries need to be operated at temperatures above 240 degrees C to ma
38          In addition, the genome editing enzymes themselves need to be optimized, and challenges regarding their editing
39                                          Imaging biomarkers need to be quantitative and user and machine independent.
40 s suitability in dealing with the current COVID-19 pandemic need to be questioned.
41                        Specifically, teduglutide cost would need to be reduced by >65% for it to reach the threshold valu
42                 These candidate markers of disease activity need to be replicated in independent datasets and, if validat
43 ency photocatalysts followed by six open questions that may need to be resolved by forming a global hydrogen taskforce in
44                   Theoretical models for the aging dynamics need to be revised accordingly.
45                          The other genes analyzed here will need to be rigorously evaluated in ongoing curation efforts t
46 lth care and research are already overstretched, priorities need to be set to guide policy makers, governments, and fundi
47 ationships between our indicators and population adaptation need to be studied further before our proposed framework can
48 e with the Number Field Sieve, the quantum SAT solver would need to be superpolynomially faster than classical SAT solver
49                                      Plant immune responses need to be tightly controlled for growth-defense balance.
50 and kinetics of divalent mercury Hg(II) chemical speciation need to be understood.