ライフサイエンスコーパス: negative regulator

1 pathway activation via downregulation of its negative regulators.

2 dually resulted in a list of 53 positive and negative regulators.

3 racellular concentrations of ATP and its key negative regulators, acetyl(acyl)-CoA.

4 AraC Negative Regulators (ANR) suppress virulence genes by di

5 The Dig1 negative regulators are part of a fungal-specific module

6 cesses was studied through analysis of their negative regulators, being the ULTRAVIOLET-B-INSENSITIVE

7 the central zone where it activates its own negative regulator, CLAVATA3 (CLV3).

8 The function of these negative regulators converged on Smoothened (SMO), an on

9 suggested that FXR may serve as an important negative regulator for manipulating Smad3 expression, an

10 ver, aCRY acts in combination with pCRY as a negative regulator for mating ability as well as for mat

11 t, gamete-specific gene GAS28 pCRY acts as a negative regulator for the induction of mating ability i

12 on of p53 in cancer by dual targeting of the negative regulators HDM2 and HDMX.

13 Negative regulators identified included Megf8, Mgrn1, an

14 results suggest that CD47 plays a role as a negative regulator in inducing protective immune respons

15 Thus, we show that FXR functions as a negative regulator in neuroinflammation and we highlight

16 dy, we demonstrate that AtRAP functions as a negative regulator in plant immunity by characterizing m

17 osphorylated by the GSK3-like kinase BIN2, a negative regulator in the BR pathway.

18 repeat (LRR)-containing protein family, as a negative regulator in the NF-kappaB signaling pathway.

19 for both TCRs and CARs suggested a role for negative regulators in both systems.

20 east, emphasizes the important role of these negative regulators in fungal transcriptional control.

21 (NSCLCs) by, for instance, mutations in the negative regulator KEAP1.

22 etween the transcription factor Nrf2 and its negative regulator, Keap1 and is able to up-regulate the

23 itro, resulting from either depletion of its negative regulators LATS1/2 or expression of a mutant fo

24 iratory supercomplexes via the mitochondrial negative regulator MCJ, and leads to decreased productio

25 eletion or pharmacological inhibition of its negative regulator MDM2, impairs GSIS, leading to glucos

26 at was associated with downregulation of its negative regulator MDM2.

27 the development of potent antagonists of the negative regulators MDM2 and MDMX and other modulators o

28 ationship in the expression of NLRP3 and its negative regulator, miR-223, suggesting a miR-223-mediat

29 omponents, together with the loss of the key negative regulator Nrdp1, act coordinately to promote GB

30 and qRT-PCR analyses show that Mr-OPY2 is a negative regulator of a transcription factor that we dem

31 ZBTB32 is therefore a novel negative regulator of Ab recall responses.

32 g a more prominent role for this ligand as a negative regulator of adult muscle mass.

33 emonstrate that host CD70 serves as a unique negative regulator of allogeneic T cell response by cont

34 bind paxillin and abrogate its actions as a negative regulator of anchorage-independent growth.

35 plex class II (MHC-II)-like molecule H2-O, a negative regulator of antigen presentation.

36 sequestration of proteins including Keap1, a negative regulator of antioxidant response.

37 ragile X Mental Retardation 1), an important negative regulator of APP translation and oligomerogenes

38 ubularin-related phosphatase MTMR14/Jumpy, a negative regulator of autophagic membrane formation.

39 ases the expression of miR-129-2, which is a negative regulator of autophagy.

40 The role of Lyn, both a positive and a negative regulator of B and myeloid cells, in chronic ly

41 Interestingly, Bim, a highly pro-apoptotic negative regulator of Bcl-2, was upregulated and recruit

42 these results establish SPRY2 as a critical negative regulator of BCR-mediated MAPK-Erk signaling in

43 nerve regeneration by identifying C5L2 as a negative regulator of BDNF secretion by pulp fibroblasts

44 vely, these findings identify FAK as a novel negative regulator of Beclin1-mediated autophagy and ind

45 POP in prostate cancer in which it acts as a negative regulator of BET protein stability and also pro

46 Thus, FlnA is a negative regulator of beta2 integrin-dependent cell adhe

47 results implicate unphosphorylated PtsN as a negative regulator of biofilm formation and establish on

48 receptor secreted by osteoblasts, is a major negative regulator of bone resorption.

49 e BRASSINOSTEROID INSENSITIVE2 (BIN2), a key negative regulator of brassinosteroid (BR) signaling, ca

50 ired for activation by suppressing TMEM20, a negative regulator of Ca(2+) extrusion.

51 We hypothesize that Herpud1 acts as a negative regulator of cardiac hypertrophy by regulating

52 hereby STIM1 is critical to deactivate a key negative regulator of cardiac hypertrophy.

53 lectively, these findings identify SIKE as a negative regulator of cardiac remodelling in multiple an

54 identified miR-218 as a posttranscriptional negative regulator of CD16a in NK cells.

55 a suggest that the Arabidopsis FZL gene is a negative regulator of cell death and disease resistance,

56 inds to the 3'UTR of Tensin 3 (TNS3) mRNA, a negative regulator of cell migration, to inhibit its tra

57 oduct (pRB) regulates transcription and is a negative regulator of cell proliferation.

58 vated glycolysis, suggesting that ncOGT is a negative regulator of cellular bioenergetics.

59 is a type 2C phosphatase that functions as a negative regulator of cellular stress-response pathways

60 We previously showed that IreB acts as a negative regulator of cephalosporin resistance in E. fae

61 Based on our findings that PHD2 is a negative regulator of chondrocyte differentiation and th

62 rrent studies, we hypothesize that Shp2 is a negative regulator of CNS myelination.

63 Thus, our data indicate that Kif13b is a negative regulator of CNS myelination.

64 signaling, miR-184 acts as a broad-spectrum negative regulator of corneal angiogenesis.

65 ressor of Cytokine Signalling 1 (chSOCS1), a negative regulator of cytokine signalling in mammals, ar

66 her with an increased expression of Wnt5a, a negative regulator of DC differentiation.

67 This identifies a novel role for LRP-1 as a negative regulator of DC-mediated adaptive immune respon

68 al deletion because of the role of RPS2 as a negative regulator of defence.

69 letion of diacylglycerol kinase (DGK)zeta, a negative regulator of diacylglycerol-mediated signaling,

70 017) identify NLRP14 as a germ-cell-specific negative regulator of DNA sensing that may be of particu

71 rough a common pathway, and define BIN1 as a negative regulator of DNM2 in vitro and in vivo during m

72 ation of muscle fibers, supporting BIN1 as a negative regulator of DNM2.

73 lular functions of dynein, DHC-1 is a strong negative regulator of EGFR signaling during vulva induct

74 ibition of TGFbeta family signaling, a known negative regulator of embryonic basal cells, is also nec

75 demonstrate that NCALD is a Ca(2+)-dependent negative regulator of endocytosis, as NCALD knockdown im

76 Rather, we identified a role for MIG6 as a negative regulator of epidermal growth factor-induced si

77 cate CONSTITUTIVE TRIPLE RESPONSE1 (CTR1), a negative regulator of ethylene signaling.

78 PKCtheta selectively inactivates the negative regulator of F-actin generation, Coronin 1A, at

79 p), a DHHC domain palmitoyltransferase, as a negative regulator of Fat signaling in growth control.

80 deacetylase activity of HDAC3 is a powerful negative regulator of fear memory formation in multiple

81 ced, and frequently colocalized with MipZ, a negative regulator of FtsZ polymerization.

82 lycopersicum) DELLA protein PROCERA (PRO), a negative regulator of GA signaling, acts in guard cells

83 f rapamycin complex 1 (MTORC1) is a critical negative regulator of general autophagy.

84 K1) is a regulator of the Warburg effect and negative regulator of glioblastoma growth.

85 M, Taylor et al. describe PD-1 as a critical negative regulator of group 2 innate lymphoid cells (ILC

86 scriptional regulator, AmrZ, which acts as a negative regulator of H2-T6SS.

87 me defects as ectocytic removal of GPR161, a negative regulator of Hedgehog signaling, permits the ap

88 ssion of Von Hippel Lindau protein (pVHL), a negative regulator of HIF, and that treatment with the c

89 early show that HspBP1 acts as an endogenous negative regulator of HIV-1 gene-expression and replicat

90 In conclusion, miR-18a-5p is a negative regulator of hPXR expression and the hPXR agoni

91 CD23 has been implicated as a negative regulator of IgE and IgG antibody responses.

92 protein (CIS, encoded by Cish) as a critical negative regulator of IL-15 signaling in NK cells.

93 our knowledge, MCPIP1 is the first described negative regulator of IL-17C signaling.

94 Here, we identify SOCS1 as a key negative regulator of IL-4-induced IRS-2 signaling and M

95 sphatase (TC-PTP), also known as PTPN2, as a negative regulator of IL-7R-STAT signaling in T cell pro

96 and functional characteristics, acting as a negative regulator of ILR and Toll-like receptor (TLR) d

97 med cell death ligand 1 (PD-L1) pathway is a negative regulator of immune activation that is upregula

98 ased Hes1 (hairy and enhancer of split-1), a negative regulator of inflammation in macrophages.

99 ation in airway disease by up-regulating the negative regulator of inflammation MyD88s.

100 d in primary immune deficiency, PLCG2, and a negative regulator of inflammation, SLAMF8.

101 lower expression of NLRP12 (which encodes a negative regulator of innate immunity) in human ulcerati

102 he H3K9 methyltransferase SETDB1 as a novel, negative regulator of innate immunity.

103 The notion that Ly9 could be a negative regulator of innate-like B cell responses was s

104 the first demonstration of IP6K1 as a novel negative regulator of inositol synthesis in mammalian ce

105 interference screen, we identify MARCH1 as a negative regulator of INSR signalling.

106 ulates the expression of TXNIP, a well-known negative regulator of insulin action.

107 The protein-tyrosine phosphatase PTP1B is a negative regulator of insulin and leptin signaling and a

108 e kinase kinase kinase 4 (Map4k4) acted as a negative regulator of insulin sensitivity in chronically

109 ogether, these results implicate Gpr182 as a negative regulator of intestinal MAPK signaling-induced

110 of FK506-binding protein 12.6/1b (FKBP1b), a negative regulator of intracellular Ca(2+) responses, re

111 ntification of Mst1 as a novel physiological negative regulator of IRF3 activation provides mechanist

112 ation revealed PACSIN1 as a novel and potent negative regulator of KCC2.

113 e demonstrate here that PD-1 is an important negative regulator of KLRG1(+) ILC-2 function in both mi

114 reduced let-7 miRNA expression via Lin28b, a negative regulator of let-7 biogenesis.

115 ophils that regulate VE-cadherin's role as a negative regulator of leukocyte transmigration.

116 This demonstrates that p62 is a negative regulator of liver inflammation and fibrosis th

117 results demonstrate that Akt3 is a specific negative regulator of macropinocytosis in macrophages.

118 ether, our data reveal that Chrdl1 acts as a negative regulator of malignant breast cancer phenotypes

119 transcriptional repressor E2F6 as a possible negative regulator of MDM2 expression.

120 The in-vitro identification of TRIB3 as a negative regulator of megakaryocytopoiesis suggests that

121 g pathway, where it interacted with PCBP2, a negative regulator of mitochondrial antiviral signaling

122 Thus, KICSTOR is a lysosome-associated negative regulator of mTORC1 signalling, which, like GAT

123 arance of A. fumigatus IL-33 functioned as a negative regulator of multiple inflammatory cytokines, a

124 suppressor protein phosphatase 2A (PP2A), a negative regulator of multiple oncogenic signaling prote

125 ltogether, we identify activin A as a second negative regulator of muscle mass, and suggest that inhi

126 Myostatin is a negative regulator of muscle mass.

127 ns, but has also been proposed in vitro as a negative regulator of myelination in Schwann cells.

128 s revealed impaired interactions with A20, a negative regulator of NF-kappaB activation, leading to p

129 3 also enhanced expression of IkBa, a potent negative regulator of NF-kappaB and cytokine production,

130 ability of miR-29b to target TNFAIP3/A20, a negative regulator of NF-kappaB signaling.

131 Loss of KEAP1, a negative regulator of NFE2L2/NRF2, modulated the respons

132 MCPIP1 is also a negative regulator of NFkappaB and AP1 activity and it i

133 mediated adenosine signaling as an intrinsic negative regulator of NK-cell maturation and antitumor i

134 NKD2 functions as a negative regulator of nkd1 transcription, consistent wit

135 A-binding protein Tristetraprolin (TTP) as a negative regulator of NLRP3 in human macrophages.

136 lly restricting atypical protein kinase C, a negative regulator of non-muscle myosin IIB.

137 ECH-associated protein 1 (KEAP1) is the main negative regulator of NRF2 and mediates ubiquitylation a

138 ed KEAP1 (also known as KLHL19), the primary negative regulator of NRF2, as a direct substrate of OGT

139 CH-associated protein 1 (KEAP1), the primary negative regulator of NRF2.

140 2, 3, 4), a negative regulator of nuclear factor erythroid 2-like 2

141 udy, we report that microRNA (miR)-181a is a negative regulator of nuclear factor kappa-light-chain e

142 eceptor interacting protein 1 (LINGO-1) is a negative regulator of oligodendrocyte differentiation an

143 eceptor interacting protein 1 (LINGO-1) is a negative regulator of OPC differentiation.

144 upport a dual role for miR-297c-5p as both a negative regulator of OPC proliferation and a positive r

145 We identified COMMD1 as a cell-intrinsic negative regulator of osteoclastogenesis that is suppres

146 ding protein subunit alpha13 (Galpha13) is a negative regulator of osteoclastogenesis.

147 ther emphasizing the importance of IRF8 as a negative regulator of osteoclastogenesis.

148 MDM2 is a negative regulator of p53 activity and an important targ

149 MDM2 expression indicating that NFATc3 is a negative regulator of p53 while a positive regulator of

150 Herpud1 is a novel negative regulator of pathological cardiac hypertrophy.

151 eness of GBM cells, and that Nrdp1 acts as a negative regulator of PCP signaling by inhibiting Dvl th

152 CpxRA two-component system was a negative regulator of PGRP-induced oxidative stress.

153 2O2 acts through an Src kinase to activate a negative regulator of PI3K signaling, SHIP-1 via phospho

154 SHIP is a negative regulator of PI3Kp110alpha activity.

155 M-1 was therefore widely accepted as a major negative regulator of platelet activation and thrombosis

156 ssues, whereas myostatin is a well-described negative regulator of postnatal skeletal and cardiac mus

157 of growing follicles, has been proposed as a negative regulator of primordial follicle activation.

158 Thus, MCPIP1 is a potent negative regulator of psoriatic skin inflammation throug

159 in Dictyostelium discoideum We identified a negative regulator of Ras signaling, C2GAP1, which local

160 nvestigated the role of Sprouty (SPRY)2 as a negative regulator of receptor and nonreceptor tyrosine

161 r, our study not only identifies FILNC1 as a negative regulator of renal cancer with potential clinic

162 The negative regulator of Rho family GTPases, p190A RhoGAP,

163 e sumoylation state of RhoGDIalpha, a master negative regulator of RhoGTPase activity and actin polym

164 conclusion, we have identified miR-23a as a negative regulator of RKIP expression in AML and have pr

165 peat containing protein 25 (LRRC25) is a key negative regulator of RLR-mediated type I interferon (IF

166 MAF1 is a conserved negative regulator of RNA polymerase (pol) III and intra

167 RseA is a negative regulator of RpoE that sequesters the sigma fac

168 of FK506-binding protein 12.6/1b (FKBP1b), a negative regulator of ryanodine receptor Ca(2+) release,

169 attern recognition receptors and is a potent negative regulator of several pathways that significantl

170 howed that expression of myostatin, a master negative regulator of skeletal muscle mass, was strongly

171 (GDF8) is a TGF-beta superfamily member, and negative regulator of skeletal muscle mass.

172 ivity and concluded that miR-124 is indeed a negative regulator of SMOX.

173 Although Csk is known as a negative regulator of Src kinases, the effects of Csk on

174 es, indicating that alpha7beta1 can act as a negative regulator of STAT3 activity.

175 Programmed death 1 (PD1) is a negative regulator of T cell responses and a determinant

176 eceptor B7 (also called CD80 and CD86), is a negative regulator of T-cell activation.

177 Expression of CD200 (OX2), a negative regulator of T-cell function that binds CD200 r

178 Programmed cell death-1 (PD-1) is a negative regulator of T-cell responses.

179 SARM1, a negative regulator of TCAM1-dependent pathways in verteb

180 at loss of the tyrosine phosphatase SHP-1, a negative regulator of TCR signaling, renders naive CD4(+

181 t al. identified the kinase Mink1 as a novel negative regulator of Th17 cell generation.

182 7 production by macrophages and is thereby a negative regulator of the antitumour response.

183 The major negative regulator of the AP is the plasma protein compl

184 e zinc finger transcription factor EGR1 as a negative regulator of the beige fat program.

185 Here, we demonstrate that HDAC1 is a negative regulator of the brown adipocyte thermogenic pr

186 ether Apc, a multifunctional protein and key negative regulator of the canonical beta-catenin (Ctnnb1

187 al reproductive function, as expected from a negative regulator of the FSH hormone.

188 IL-10 feedback loop, whereas expression of a negative regulator of the hIL-10 feedback loop, dual-spe

189 human monoclonal antibodies against CD46, a negative regulator of the innate immune system, and cons

190 e that suppressor of IKKvarepsilon (SIKE), a negative regulator of the interferon pathway, attenuates

191 Moreover, genetic inactivation of Osr2, a negative regulator of the odontogenic function of the Bm

192 Phosphatase and tensin homolog (PTEN) is a negative regulator of the phosphatidylinositol 3-kinase

193 1 gene, which encodes p120 RasGAP (RASA1), a negative regulator of the Ras small GTP-binding protein.

194 SUFU is the main negative regulator of the SHH pathway and is essential d

195 previously reported that the SPH CLIPA2 is a negative regulator of the TEP1-mediated response by show

196 Prdm16, a negative regulator of the TGF-beta pathway, is directly

197 with concomitant downregulation of BAMBI, a negative regulator of the TGFbeta signaling pathway.

198 Our results establish GDE3 as a negative regulator of the uPAR signaling network and, fu

199 e identify possible links with Dickkopf-1, a negative regulator of the wnt pathway, and propose that

200 Ptpn14 encodes a negative regulator of the Yap oncoprotein and is necessa

201 ogy Splicing Regulatory Protein (KHSRP) as a negative regulator of this pathway.

202 finger transcription factor Th-POK is a key negative regulator of thymic NKT17 cell differentiation

203 It is a negative regulator of tissue repair and regeneration in

204 kine signaling (SOCS)1 is a cross-functional negative regulator of TLR and cytokine receptor signalin

205 demonstrate that TLR10 functions as a broad negative regulator of TLR signaling and suggests that TL

206 an inhibitor of the NF-kappaB pathway and a negative regulator of TLR signaling, in ligated TLR9(-/-

207 our findings identify NLRP11 as a conserved negative regulator of TLR signalling in primate cells an

208 suggest that CLIP170 serves as an intrinsic negative regulator of TLR4 signaling that targets TIRAP.

209 Bioinformatics analysis identified Tollip, a negative regulator of TLR4, as a target of miR291b.

210 show that TLR9(471-1032) is also a dominant-negative regulator of TLR9 signaling.

211 rovides evidence for the role of miR-17 as a negative regulator of TNF-alpha signaling by modulating

212 Smad7 is a negative regulator of transforming growth factor-beta, w

213 uitin-specific peptidase 18 (USP18) is a key negative regulator of type I IFN signaling.

214 as a positive regulator of autophagy, but a negative regulator of type I interferon (IFN) signaling.

215 phosphorylation of, and thus inactivating, a negative regulator of Ulk1, mechanistic target of rapamy

216 eferred to as ABIN1, whose gene product is a negative regulator of various inflammatory signaling pat

217 minus and has been reported to function as a negative regulator of VEGF signaling in endothelial cell

218 t the adaptor protein TAX1BP1 functions as a negative regulator of virus-induced apoptosis.

219 otein 5 (CXXC5) with Dishevelled as one such negative regulator of WNT in hair follicle regeneration.

220 data indicate that OTG functions as a novel negative regulator of Wnt signaling during development b

221 e recent discovery that Tnks targets Axin, a negative regulator of Wnt signaling, for proteolysis.

222 tro results highlight the role of Runx2 as a negative regulator of Wnt/beta-catenin pathway activity

223 Here we demonstrate that Apcdd1, a negative regulator of Wnt/beta-catenin signaling, is exp

224 ion approaches revealed that ACAP2 acts as a negative regulator of WPB exocytosis.

225 ncestral BCCPs that gained a new function as negative regulators of ACCase after initial loss of the

226 ies on differential activity of positive and negative regulators of alternative polyadenylation.

227 ne protease homologs (SPHs) are positive and negative regulators of Anopheles gambiae immune response

228 uction of MtCLE12 and MtCLE13 peptide genes (negative regulators of AON) in nodulating roots is not a

229 It has been reported recently that two negative regulators of Arabidopsis cryptochromes, Blue l

230 Our data identify sIgM as negative regulators of BCR signaling and suggest that th

231 Arabidopsis CDF genes are important negative regulators of CONSTANS (CO) transcription, but

232 iated macrophages or increased expression of negative regulators of cytotoxic T-cell function.

233 iously unknown roles for Claspin and Chk1 as negative regulators of DNA replication in the absence of

234 mechanism through which they act as positive/negative regulators of expression of genes and other miR

235 at WRKY18 and WRKY40 function redundantly as negative regulators of flg22-induced genes often to prev

236 a genetic screen in Aspergillus nidulans for negative regulators of fungal SM gene clusters and we ha

237 Patched (Ptch) receptors are critical negative regulators of Hedgehog signaling, where Ptch1 l

238 regulatory T cells (Tregs) are indispensable negative regulators of immune responses.

239 suppressive CD4 T cells that act as critical negative regulators of inflammation in various biologica

240 e-specific proteins demonstrated in vitro as negative regulators of inflammatory responses.

241 iver both miR-29a and miR-29c were important negative regulators of insulin signaling via phosphatidy

242 ntified 20 transcription factors as putative negative regulators of lipid production by using RNA-seq

243 s (Arabidopsis thaliana) MKP1, are important negative regulators of MAPKs and play a crucial role in

244 Moreover, genes for negative regulators of maturation such as Sox2 and Ednrb

245 HDACs are known to be powerful negative regulators of memory formation, but it is not c

246 icial miRNA target mimic (MIM) to screen for negative regulators of miR156.

247 as mutation cooperatively led to decrease in negative regulators of mitogen-activated protein kinase

248 yperactivity in the SC lineage, we disrupted negative regulators of mTORC1, including TSC2 or TSC1, i

249 cate BT gene family members act as conserved negative regulators of nitrate uptake genes and NUE in p

250 Consistent with these results, negative regulators of NMM-II stabilize intercellular br

251 uced protein 3 (TNFAIP3), one of the crucial negative regulators of nuclear factor kappaB activation

252 We hypothesized that germ cells express negative regulators of nucleic acid sensing (NAS) in ste

253 that Setd1b also promotes the expression of negative regulators of oocyte development with multiple

254 Expression of ORM genes (negative regulators of PHS synthesis) and of fatty acid

255 rly during infection, miR863-3p silences two negative regulators of plant defence, atypical receptor-

256 ations in the Ras pathway due to the loss of negative regulators of RAS may be a common event in basa

257 1 directly targets and reduces expression of negative regulators of RAS/MAPK signaling.

258 HDA9 directly binds to the promoters of key negative regulators of senescence and this association r

259 y ligands myostatin, GDF11, and activins are negative regulators of skeletal muscle mass, which have

260 Myostatin (or GDF8) and GDF11 are potent negative regulators of skeletal muscle mass.

261 tion of the PI3K-PKB pathway, or the loss of negative regulators of T cell activation, such as the E3

262 that RORgammat and Tbet act as positive and negative regulators of Th22 differentiation, respectivel

263 noblastoma (Rb), p107, and p130 are critical negative regulators of the cell cycle and contribute to

264 bers of the AJUBA family of LIM proteins are negative regulators of the Hippo pathway.

265 IFNs in inducing antiviral genes, as well as negative regulators of the IFN response, such as USP18 a

266 e JASMONATE ASSOCIATED MYC2-LIKEs, which are negative regulators of the JA pathway.

267 -M, direct targets of miR-155 that are known negative regulators of the LPS response, were elevated i

268 richment for genomic aberrations of multiple negative regulators of the NF-kappaB pathway, including

269 g responses by targeting for degradation the negative regulators of the pathway, Smad6 and Smad7, and

270 d cancer, highlighting the important role of negative regulators of the pathway.

271 ne expression, including the upregulation of negative regulators of the phenylpropanoid pathway, and

272 , angiotensin 1-7 (Ang-[1-7]), are important negative regulators of the RAS.

273 They are considered putative negative regulators of the transport of the phytohormone

274 itutive internalization property that clears negative regulators of the WNT-receptor complex from the

275 processes, PTPs are usually perceived as the negative regulators of these events and therefore tumor

276 RELATED SEQUENCE 7 (FRS7) and FRS12, act as negative regulators of these processes.

277 neration Sequencing of microRNAs to identify negative regulators of TLR4 signaling reciprocally modul

278 ike, Sp1BS, and Inr elements all function as negative regulators of transcription, and each was found

279 The ubiquitin ligases CBL and CBL-B are negative regulators of tyrosine kinase signaling with es

280 cating that SPL9-group genes may function as negative regulators of wall ingrowth deposition in PP TC

281 eterozygous damaging de novo mutations in 12 negative regulators of Wnt, BMP, and Ras/ERK signaling (

282 A), functioning as a dual (both positive and negative) regulator of CKI1 expression, presumably via t

283 ssociated macrophages or antibodies blocking negative regulators on T cells-could provide improved an

284 in the TP53 gene or by overexpression of its negative regulators, oncoproteins MDM2/MDMX.

285 ing proliferation by ablating the cell cycle negative regulator p27 (also known as Cdkn1b) in Sox2 mu

286 expression of the prostaglandin F2a receptor negative regulator (PTGFRN), an inhibitor of prostagland

287 coordinately repressed five Wnt/beta-catenin negative regulators, resulting in increased Wnt signalin

288 UT2 is a negative regulator shared across STAT3 and mTORC2 signal

289 In contrast, H-NS and CRP function as negative regulators since expression of lngA was up-regu

290 IFN signaling is controlled by the inducible negative regulators suppressor of cytokine signaling 1 (

291 Rather than being dominant-negative regulators, Tcf1 short isoforms are adequate in

292 tones for binding to the BRD and acting as a negative regulator that inhibits histone H3 acetylation.

293 r (Foxp3 long intergenic noncoding RNA) is a negative regulator that tunes Foxp3 expression, resultin

294 Signal activation is balanced by negative regulators that are generally considered to ter

295 CRF6 functions during oxidative stress as a negative regulator to control this cytokinin-associated

296 that, at some point, has to be controlled by negative regulators to maintain tissue homeostasis.

297 ight-chain-enhancer of activated B cells and negative regulators tumor necrosis factor-alpha-induced

298 y suggests that KFB(CHS) serves as a crucial negative regulator, via mediating CHS degradation, coord

299 es two dynamical motifs: neutralization of a negative regulator, which characterizes how Akt indirect

300 Both positive and negative regulators within the axon and Schwann cell fun