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1                                              Neisserial adhesin A (NadA), a trimeric autotransporter
2 tched reference strain (5/99, which included neisserial adhesin A), both of which were used in vaccin
3      The functions of type IV pili and other neisserial adhesins are discussed in the specific contex
4                                        Thus, neisserial adhesion via either of at least two different
5                               Genome-derived neisserial Ag (GNA) 1870 is a meningococcal vaccine cand
6 of polysaccharide-specific Ig in response to neisserial and other gram-negative porin-expressing bact
7 ain engineered to overexpress genome-derived neisserial antigen (GNA) 1870, a lipoprotein discovered
8                               Genome-derived neisserial antigen 2132 (GNA2132) is a novel vaccine can
9 t activities in DNA repair: one is a typical Neisserial AP endonuclease (NApe), whereas the other is
10 ly conserved 9-bp core sequence, whereas the neisserial apparatus binds a 10-bp motif.
11             Genetic recombination impacts on neisserial biology in two ways: (i) specific loci underg
12              Based on these frequencies, six Neisserial clinical isolates could be grouped into three
13 tudy, we found that DNA derived from various neisserial co-colonizers of the human nasopharynx increa
14  in understanding the mechanisms that enable neisserial colonisation, in terms of the role of type IV
15  microenvironment, and a multistep model for neisserial colonization of mucosal epithelia is proposed
16  the cell, the earliest demonstrable step in neisserial competence.
17  fusion proteins, suggesting that additional neisserial components are involved.
18 ey are a long-standing, integral part of the neisserial dcw gene cluster.
19 ociated with the development of disseminated neisserial disease, and did not require opacity outer me
20 ng frequencies, indicating that heterologous neisserial DNA modulates phase variation in a transforma
21  ermC, the vector contains two copies of the neisserial DNA uptake sequence to facilitate high-freque
22 ncies were also increased in the presence of neisserial DNA.
23  other is a specialised 3'-phosphodiesterase Neisserial exonuclease (NExo).
24                         We have identified a neisserial gene, hemO, that is essential for heme, hemog
25 ith differences in repeat length between the neisserial genome sequences is further corroborative evi
26 sts it is an essential gene (engA, essential neisserial GTPase).
27                   When the gene encoding the neisserial heme oxygenase, hemO, was replaced with pigA,
28    The deduced amino acid sequences of these neisserial hemoglobin receptors were also highly related
29 ntigens (factor H-binding protein [fHbp] and neisserial heparin-binding antigen).
30 o-glutamine exchange in the active center of neisserial HtrA.
31  Several lines of evidence indicate that the neisserial IgA1 protease is directly responsible for thi
32 pe IV pili play an active role in initiating neisserial infection of the mucosal surface in vivo.
33 t in innate immune defenses against invasive neisserial infections.
34 s the transcriptional activity of two common neisserial intergenic components.
35 egy for vaccine development has targeted the neisserial iron import systems.
36              Evidence for the role of Fur in neisserial iron regulation has been indirect because of
37 f predominantly "transparent" (Opa-negative) neisserial isolates from persons with invasive disease,
38                   Approximately 95 different neisserial isolates tested positive by Western blotting
39 eity of this protein, the 2086 genes from 63 neisserial isolates were sequenced.
40                     Human IgGs that bind the neisserial L7 lipooligosaccharide (LOS) are bactericidal
41                      Thus, the Opa family of neisserial ligands may interact with several members of
42                            The inner core of neisserial lipooligosaccharide (LOS) contains heptose re
43                                              Neisserial lipooligosaccharide (LOS) contains three olig
44  and phosphoethanolaminylation of lipid A on neisserial lipooligosaccharide (LOS), a major cell-surfa
45                                              Neisserial lipooligosaccharides (LOSs) are a family of c
46 identification and characterization of nlaB (neisserial LPA acyltransferase B), the second LPA acyltr
47 d sequence from the previously characterized neisserial LPA acyltransferase homologue nlaA.
48 risingly, picogram-per-milliliter amounts of neisserial LPS were also found to be highly synergistic
49             Overexpressing components of the neisserial mismatch repair system partially alleviated D
50                                              Neisserial mod alleles also contained a hypervariable re
51                                              Neisserial Opa proteins function as a family of adhesins
52 receptor-binding function in the majority of neisserial Opa proteins.
53                                          The neisserial opacity (Opa) proteins are a family of antige
54                                          The neisserial opacity (Opa) proteins are phase-variable, an
55  Omp31, Agrobacterium tumefaciens Omp25, and neisserial opacity proteins (Opa).
56 ing infections caused by multidrug-resistant neisserial or streptococcal strains.
57                                          The neisserial outer membrane protein, PorB, is a TLR2 ligan
58 y designated FrpB, an iron-regulated, 76-kDa neisserial outer membrane protein, shows sequence homolo
59  constitute the vast majority of channels in neisserial outer membranes and can be subdivided within
60                         PorB is required for neisserial pathogenesis and can elicit a Toll-like recep
61 is the most dissimilar of the three types of neisserial pilE loci.
62 eat sequence, a feature present in all other neisserial pilin genes examined to date.
63 th the N-terminal conserved regions of other neisserial pilin proteins.
64 ivariable and hypervariable regions of other neisserial pilins and displays a large deletion in a hyp
65 icited when CPS is conjugated to the class 3 neisserial porin (CPS-porin).
66                                PorB is a pan-neisserial porin expressed regardless of organisms' path
67                                          The neisserial porin P.I is a GTP binding protein that forms
68                                The effect of neisserial porin PorB on activation-induced cell death w
69                                       Due to neisserial porin's ability to activate B cells and poten
70 nificant for elucidating the mechanism(s) of neisserial porin's immune stimulatory activity.
71 y effect on the B-cell-stimulatory effect of neisserial porins (essential for the adjuvant activity o
72                                              Neisserial porins are strong immune adjuvants and B cell
73                                          The neisserial porins are the major protein components of th
74                                 Furthermore, neisserial porins co-localize with mitochondria of targe
75 The mechanism of the antiapoptotic effect of neisserial porins could be explained by the protein-prot
76                                              Neisserial porins have been shown to act as adjuvants in
77                                              Neisserial porins have been shown to act as B cell mitog
78                                              Neisserial porins increased the surface expression of th
79             In addition, incubation with the neisserial porins increased the T lymphocyte costimulato
80                                              Neisserial porins interact with target cells to localize
81  potent adjuvant activity, the effect of the neisserial porins on T-B cell interactions and T cell co
82                                The effect of neisserial porins on the immune system also involves int
83 a support the hypothesis that the ability of neisserial porins to improve the immune response to poor
84 does not significantly affect the ability of neisserial porins to induce the costimulatory ligand B7-
85 rins (essential for the adjuvant activity of neisserial porins), B cells from both murine strains wer
86           The immunopotentiating activity of neisserial porins, the major outer membrane protein of t
87 sm behind the immunopotentiating activity of neisserial porins.
88 ent reports of the crystal structures of the neisserial receptor proteins TbpA and TbpB, each solved
89 tified one small RNA, herein named NrrF (for neisserial regulatory RNA responsive to iron [Fe]), whic
90                                The commensal neisserial species were identified as reservoirs for all
91 GAA) present frequently in the chromosome of neisserial species.
92  Although FetA is commonly expressed by most neisserial strains and is a potential vaccine candidate
93  is present in different copy numbers in the neisserial strains examined.
94                     Unexpectedly, none of 10 Neisserial strains tested bound native properdin.
95 of Hb receptors or the general mutability of Neisserial strains.
96 f a complement down-regulator protein to the neisserial surface by specific Ab may enhance intrinsic
97                                              Neisserial surface protein A (NspA) is a highly conserve
98                                              Neisserial surface protein A (NspA) is currently being i
99 c acid, factor H binding protein (fHbp), and neisserial surface protein A (NspA) to regulate the alte
100 g expression of capsule (select serogroups), Neisserial surface protein A (NspA), factor H (fH) bindi
101 rected against the highly conserved protein, neisserial surface protein A (NspA).
102 ein currently undergoing clinical trials and Neisserial surface protein A.
103      In contrast to type IV pili, many other neisserial surface structures are not involved in cortic
104                  Little is known about other neisserial targets for complement proteins C3 and C4, wh
105   Complementation studies indicated that the neisserial Ton system cannot interact with the E. coli F
106                                          The neisserial transferrin binding proteins (Tbps) comprise
107 region with potential cleavage sites for the neisserial type 1 and type 2 IgA1 proteases.
108                                              Neisserial type 2 IgA1 protease cleaves purified LAMP1 i
109  to induce cortical plaques, indicating that neisserial type IV pili are required for cortical plaque
110  was delineated by a 33-bp repeat containing neisserial uptake sequences located downstream of col.
111 ream of this promoter is an inverted pair of neisserial uptake signal sequences, which are commonly c
112 the choice of complement sources to evaluate neisserial vaccine candidates.
113 the choice of complement sources to evaluate neisserial vaccine candidates.

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