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1 pared from the enediyne antitumor antibiotic neocarzinostatin chromophore.
2 ctive synthetic route to the natural product neocarzinostatin chromophore (1) is described.
3 f the product epoxy alcohol (58) then formed neocarzinostatin chromophore aglycon (2, 71% yield).
4                   Under anaerobic conditions neocarzinostatin chromophore, an enediyne antibiotic, fo
5 ynthesis of the naphthoic acid moiety of the neocarzinostatin chromophore and further support the ear
6 cule DNA cleaving agents, such as bleomycin, neocarzinostatin chromophore, and lomaiviticin A, in pla
7 c acid moiety and its incorporation into the neocarzinostatin chromophore are catalyzed by five enzym
8                                          The neocarzinostatin chromophore consists of a nine-membered
9  analogue 3, an alpha-D-fucose derivative of neocarzinostatin chromophore, formed in 42% yield by a t
10 argets for the enediyne antitumor antibiotic neocarzinostatin chromophore in a base-catalyzed, radica
11 own in a previous study that thiol-activated neocarzinostatin chromophore is able to cleave duplex DN
12 g agents, including gamma-radiolysis and the neocarzinostatin chromophore (NCS).
13 al covalent adduct formed by thiol-activated neocarzinostatin chromophore (NCS-chrom) and a RNA-DNA h
14 on of the complexes of DNA and postactivated neocarzinostatin chromophore (NCS-chrom) compounds revea
15                                              Neocarzinostatin chromophore (NCS-chrom) has been found
16 argets for the enediyne antitumor antibiotic neocarzinostatin chromophore (NCS-chrom) in a base-catal
17                                              Neocarzinostatin chromophore (NCS-Chrom) induces highly
18                                              Neocarzinostatin chromophore (NCS-Chrom) induces strong
19 ained from the enediyne antitumor antibiotic neocarzinostatin chromophore (NCS-chrom), we have prepar
20  observations that treatment of DNA with the neocarzinostatin chromophore resulted in large amounts o
21 aphthoic acid and its incorporation into the neocarzinostatin chromophore with free naphthoic acids s

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