ライフサイエンスコーパス: neocortex

1 key architectonic feature of the developing neocortex.

2 he olfactory archicortex with the prefrontal neocortex.

3 llows "up-and-down" state transitions in the neocortex.

4 ile (11)C-PiB bound diffusely throughout the neocortex.

5 ccess to neuronal activity across all of the neocortex.

6 spatiotemporal enrichment within developing neocortex.

7 spiration and another that is coupled to the neocortex.

8 ns, and defective synaptic inhibition in the neocortex.

9 set of neurons, critical for function of the neocortex.

10 oneural activity in the developing mammalian neocortex.

11 firing modes in circuit assembly within the neocortex.

12 in the corresponding functional area of the neocortex.

13 ics and shapes the routing of information in neocortex.

14 y expressed during development of the murine neocortex.

15 at the apical endfeet of radial glia of the neocortex.

16 c extra-somatic glutamatergic input from the neocortex.

17 are often attributed to our recently evolved neocortex.

18 in the development of the vasculature in the neocortex.

19 neurons all along the pathway leading to the neocortex.

20 sponding ligands expressed in the developing neocortex.

21 ppression of WNT inhibitor expression in the neocortex.

22 various germinal zones of developing ferret neocortex.

23 ytic differentiation in the developing mouse neocortex.

24 elevated expression of WNT inhibitors in the neocortex.

25 atory neurons for each cortical layer in the neocortex.

26 implications for signal processing in human neocortex.

27 ive basket cell terminals in hippocampus and neocortex.

28 the consolidation of spatial memories to the neocortex.

29 y to understanding information processing in neocortex.

30 teractions across several millimeters of the neocortex.

31 developmental roles in olfactory cortex and neocortex.

32 a correct radial migration in the developing neocortex.

33 g controls neuronal ploidy in the developing neocortex.

34 n the control of SSNs in the early postnatal neocortex.

35 ineage, coincident with the emergence of the neocortex.

36 nd differentiation of NPCs in the developing neocortex.

37 number of bRGs and IPCs and the size of the neocortex.

38 ed in the substantia nigra compared with the neocortex.

39 casting experience-specific "index codes" to neocortex.

40 ense superficial distribution in the growing neocortex.

41 or the operation of neuronal circuits in the neocortex.

42 y timed transfer of local information to the neocortex.

43 raneously generate neurons in the developing neocortex.

44 cells in temporal and prefrontal association neocortex.

45 pment of neurons and oligodendrocytes in the neocortex.

46 ics of excitatory evoked response in sensory neocortex.

47 bitory interneurons scattered throughout the neocortex.

48 upted neuronal migration in developing mouse neocortex.

49 g regions comparable with those found in the neocortex.

50 neuronal migration pattern in the developing neocortex.

51 transient firing in hippocampus and sensory neocortex.

52 he core Fzd8 promoter in the mouse embryonic neocortex.

53 underlying pyramidal neuron diversity in the neocortex.

54 control of sensory-evoked signal flow in the neocortex.

55 ed sharply from those seen previously in the neocortex.

56 endent precise columnar microcircuits in the neocortex.

57 nships in human cerebral organoids and fetal neocortex.

58 ntal and evolutionary expansion of the human neocortex.

59 n is transferred from the hippocampus to the neocortex.

60 thalamus, medial temporal lobe and temporal neocortex.

61 ts of neurons in CA1 and CA3, but not in the neocortex.

62 y linked to decreased thickness of the human neocortex.

63 iatum and absent in the nonhuman African ape neocortex.

64 s cytoarchitectural changes in the embryonic neocortex.

65 ctional regulation of the motor areas of the neocortex.

66 of GABAergic inhibitory interneurons to the neocortex.

67 d regulate the maturation of the associative neocortex.

68 halamic nuclei that provide input to sensory neocortex.

69 atergic neurons of the telencephalon-derived neocortex.

70 pocampal memory of wake experiences into the neocortex.

71 ferentiation and migration in the developing neocortex.

72 mechanism, which pre-dates the evolution of neocortex.

73 tatory inputs originating from contralateral neocortex.

74 tion of dendritic signaling in the mammalian neocortex.

75 represent the major output cell type of the neocortex.

76 of GABAergic inhibitory interneurons to the neocortex.

77 ants of neuron subtype identity in the mouse neocortex.

78 ely Reln and Pkmzeta, in the hippocampus and neocortex.

79 teractome is coregulated in developing human neocortex.

80 eas in other mammals, they are also found in neocortex.

81 s/entorhinal; 21%), or stage 3 (extension to neocortex; 14%).

82 ssed in neural progenitors of the developing neocortex [17-19].

83 eas [(11) C]PIB bound throughout association neocortex, [(18) F]AV-1451 was selectively retained in p

84 expressed genes (DEGs) (82), followed by the neocortex (76), hypothalamus (63), and cerebellum (26).

85 uantify the rate of pruning in the mammalian neocortex across a broad developmental time window and f

86 f olfactory CR cells, which migrate into the neocortex after they have acted as axonal guidepost cell

87 The volumes of the neocortex, allocortex, and white matter structures were

88 The recurrent synaptic architecture of neocortex allows for self-generated network activity.

89 stem cells recapitulates development of the neocortex, an area affected in both fragile X syndrome a

90 rity of excitatory synapses in the mammalian neocortex and are motile structures with shapes and life

91 holding for large and small synapses in the neocortex and brainstem.

92 ordings from a variety of cells in the mouse neocortex and cerebellum.

93 sophila empty spiracles (ems)] RGCs in mouse neocortex and chick forebrain and found evidence for bot

94 ivity in large neuronal ensembles from mouse neocortex and compare it to a recurrent network model, w

95 for normal gyration of the developing human neocortex and for normal cognitive ability.

96 etworks regulated by Foxp1 in the developing neocortex and found that such networks are enriched for

97 nhibitory GABA actions in the neonatal mouse neocortex and hippocampus in vivo.

98 on to quantify neuronal communication in the neocortex and hippocampus of rats during wakefulness and

99 dulates oscillatory neuronal activity in the neocortex and hippocampus on a cycle-by-cycle basis.

100 olved with nonmotor functions, including the neocortex and hippocampus, but whether mutant LRRK2 cont

101 c sensorimotor information between the rat's neocortex and hippocampus.

102 the primary site of interactions between the neocortex and hippocampus.

103 escribed as a wall of inhibition between the neocortex and hippocampus.

104 e mice, GABAA receptors in the frontal motor neocortex and hypothalamic (tuberomammillary nucleus) hi

105 development of hyperexcitability within L2/3 neocortex and in broader circuit and behavioral contexts

106 n defects previously reported in human fetal neocortex and in the developing forebrains of other mous

107 contains the major projection neurons of the neocortex and is composed of two major cell types: regul

108 onal types in layers 1, 2/3, and 5 of mature neocortex and mapped the connectivity between more than

109 into the function of FOXP1 in the developing neocortex and may reveal molecular pathways at risk in A

110 difficulty of the spatial tasks rests on the neocortex and on the limitations of working memory, not

111 um is a gray-matter structure that underlies neocortex and reciprocates connections with cortical and

112 emonstrate that OSTN is expressed in primate neocortex and restricts activity-dependent dendritic gro

113 of the elastic stiffness of the injured rat neocortex and spinal cord at 1.5 and three weeks post-in

114 trongly expressed in neurogenic areas of the neocortex and supports the self-renewing potential of mo

115 for the production of behaviour, such as the neocortex and thalamus, are integrated with reward signa

116 distinct laminar pattern in the adult mouse neocortex and that their cell type-specific expression d

117 widespread imaging abnormalities of the ALS neocortex and the accepted relationship between ALS and

118 ck circuit that bidirectionally connects the neocortex and the cerebellum.

119 escriptions of propagating activity for both neocortex and the model: convergent clusters comprised o

120 the claustrum, a nucleus located between the neocortex and the striatum, yet the functions of cortico

121 s not strongly active in the mouse embryonic neocortex, and blocking SHH signaling in human cerebral

122 istinct cell populations in the hippocampus, neocortex, and cerebellum during development.

123 he C57BL/6J mouse hypothalamus, hippocampus, neocortex, and cerebellum to determine estrous cycle-spe

124 asticity and learning in the mammalian adult neocortex, and provides insight into the function of bra

125 loping human CNS, with focus on the cerebral neocortex, and the insights these findings provide into

126 ntribute to cognitive processes in the human neocortex, and their long-term plasticity can alter the

127 tion of superficial layer CPN throughout the neocortex, and to refine precise area-specific developme

128 rebrain and thalamus, anterior cingulate and neocortex, and white matter of cerebrum, cerebellum, and

129 th the motor areas and nonmotor areas of the neocortex, and with the hypothalamus.

130 Almost all areas of the neocortex are connected with the claustrum, a nucleus lo

131 As major efforts to model the neocortex are currently underway, it has become increasi

132 ical regions such as the hippocampus and the neocortex are defined by morphology, physiology, and gen

133 The thalamus and neocortex are intimately interconnected via a reciprocal

134 ts effects on inhibitory transmission in the neocortex are not understood.

135 rebrain, yet regional differences in primate neocortex are pronounced, with enrichment in circuits th

136 Radial glia, the neural stem cells of the neocortex, are located in two niches: the ventricular zo

137 ential for the functional regulation of many neocortex areas, perhaps all, as well as of the hypothal

138 transformative role in growth and folding of neocortex as well as archicortex.

139 ory, synapses and facilitated SD in both the neocortex as well as brainstem dorsal medulla autonomic

140 erized by synapse loss (predominantly within neocortex) as well as deposition of certain distinctive

141 adenylated and total RNA obtained from human neocortex at different stages of development, and we app

142 orsal cerebral wall, which gives rise to the neocortex, at embryonic day 14.5.

143 aling was strongly active in the human fetal neocortex but Shh signaling was not strongly active in t

144 e highest expression in the developing human neocortex, but its functions remained unknown.

145 the presence of Lewy body-like inclusions in neocortex, but not hippocampal alpha-synuclein pathology

146 The amyloid effect was observed with tau in neocortex, but not with tau in entorhinal cortex, which

147 ngth of connections between areas of macaque neocortex by comparing its results with published data f

148 trode array recordings from human and monkey neocortex by examining the spike-triggered LFP average (

149 structural and functional maturation of the neocortex by refining the final number of cortical neuro

150 suggesting that perturbing MEF2C function in neocortex can produce autistic- and ID-like behaviors in

151 these results show that the adult mammalian neocortex can readily absorb completely new information

152 , single-cell transcriptomics of hundreds of neocortex cells reveal that many lncRNAs are abundantly

153 in AD-sensitive areas extending to the whole neocortex, compared with the FDG-negative subgroup.

154 The neocortex comprises multiple information processing stre

155 The neocortex contains glutamatergic excitatory neurons and

156 The neocortex contains hundreds to thousands of distinct sub

157 ocampal projections on targets in the limbic neocortex could contribute to components of schizophreni

158 ingle-cell RNA-seq in samples from the human neocortex demonstrate that long noncoding RNAs (lncRNAs)

159 rojections from layer 5 neurons in the mouse neocortex depends on the high levels of expression of th

160 ownstream target of mTOR, is elevated in the neocortex, despite normal mTOR activity.

161 diverse progenitor cells contribute to human neocortex development, we examined forebrain progenitor

162 The human neocortex differs from that of other great apes in sever

163 oss the human medial temporal lobe (MTL) and neocortex during sleep and wakefulness, and during visua

164 n shaping computational neurodynamics in the neocortex, especially in prefrontal regions.

165 not distinguished diverse cell types in the neocortex, even though different cell types possess dist

166 ticity mechanisms are not uniform within the neocortex, even within a cortical layer, but are special

167 In the mammalian neocortex, excitatory neurons provide excitation in both

168 Neurons in the neocortex exhibit spontaneous spiking activity in the ab

169 ce statement: The neural architecture in the neocortex exhibits constant remodeling.

170 Phasic release of acetylcholine (ACh) in the neocortex facilitates attentional processes.

171 Phasic release of acetylcholine (ACh) in the neocortex facilitates attentional processes.

172 Despite the importance of the mammalian neocortex for complex cognitive processes, we still lack

173 Laminar recordings in somatosensory neocortex from anesthetized mice and awake monkeys suppo

174 tand the evolutionary expansion of the human neocortex from rodents, similar approaches have been use

175 ortho-retronasal olfaction; the bauplan for neocortex had higher-level association functions derived

176 tein extracted from stimulated slices or the neocortex harvested from stimulated intact mice.

177 The mammalian neocortex has a repetitious, laminar structure and perfo

178 erse progenitors that give rise to the human neocortex have been difficult to characterize because pr

179 ot observed in LRRK2 mutant neurons from the neocortex (hereafter, cortical neurons) or the hippocamp

180 aminar-expression profiles in the developing neocortex, highlighting their important roles in brain d

181 Thus, the neocortex homolog cannot be found in the classical repti

182 eurons for 742 discrete locations across the neocortex in a chimpanzee.

183 Perfusion is reduced in the cerebral neocortex in Alzheimer's disease.

184 e matter and germinal matrix relative to the neocortex in both infants with and without IVH.

185 anding visual processing but the function of neocortex in general.

186 anding visual processing but the function of neocortex in general.

187 ring the tremendous overall expansion of the neocortex in human evolution, it has proven difficult to

188 y is among the first to describe its role in neocortex in relation to biophysical correlates of memor

189 Despite extensive investigations of the neocortex in the domestic cat, little is known about neu

190 aneous EPSCs in the immature hippocampus and neocortex in vivo SIGNIFICANCE STATEMENT: We report a no

191 ction in both free solution and in adult rat neocortex in vivo, revealing IgG diffusion in free mediu

192 onto layer 2/3 neurons in the somatosensory neocortex in vivo.

193 ated reconstruction of a sub-volume of mouse neocortex in which all cellular objects (axons, dendrite

194 ) receptor blockade stabilizes spines in the neocortex, in CA1 it transiently increased the rate of s

195 atches from layer 5 pyramidal neurons in rat neocortex, in physiological external calcium (1-2 mM).

196 onal regulation of the nonmotor areas of the neocortex, including the prefrontal, associative, sensor

197 ical evidence on how the hippocampus and the neocortex interact dynamically when acquiring and then e

198 solimbic learning processes reorganizing the neocortex into a chronic pain state.

199 The sensory neocortex is a highly connected associative network that

200 The neocortex is a mammalian-specific structure that is resp

201 The standard architecture of neocortex is a network with excitation and inhibition in

202 quantitatively evaluate the hypothesis that neocortex is a relatively homogeneous tissue, with small

203 ary role in regulating the maturation of the neocortex is an increase in inhibitory neurotransmission

204 Mammalian neocortex is characterized by a layered architecture and

205 The mammalian neocortex is composed of two major neuronal cell types w

206 y consistent transcriptional architecture in neocortex is correlated with resting state functional co

207 Acetylcholine in the neocortex is critical for executive function [1-3].

208 hat transects serotonin axons running in the neocortex is followed by local regression of cut seroton

209 The neocortex is found only in mammals, and the fossil recor

210 their similarity to corresponding layers of neocortex is greater than that of superficial layers.

211 neurons, although their localization in the neocortex is less well understood.

212 However, neocortex is not a feedforward architecture.

213 on types, although their precise role in the neocortex is not well described.

214 cts operation of neurons and networks in the neocortex is poorly understood, mostly because modulatio

215 An expansion of the cerebral neocortex is thought to be the foundation for the unique

216 Frontal neocortex is thought to support our highest intellectual

217 Evolution of the mammalian neocortex (isocortex) has been a persisting problem in n

218 imary somatosensory cortex is located in the neocortex just anterior to the main vertical fissure, an

219 standing of the synaptic organization of the neocortex largely depends on the available knowledge reg

220 sory, and visual cortices) and layers of the neocortex (layers III, IV, and V) and cerebellum (granul

221 tical period sculpt the circuitry within the neocortex, leading to changes in the functional response

222 hat conditional ablation of Kcnq2 from mouse neocortex leads to hyperexcitability of layer 2/3 (L2/3)

223 older species, the archer fish, which lacks neocortex-like cells.

224 the selective degeneration of neurons in the neocortex, limbic system, and nucleus basalis, among oth

225 mmals, the claustrum is directly adjacent to neocortex, making the definition of claustral boundaries

226 in local circuits of associational areas of neocortex manifest from a background, sleep-associated d

227 hus, robust SHH signaling in the human fetal neocortex may contribute to bRG and IPC expansion and ne

228 phological innovations such as the mammalian neocortex may involve the evolution of novel regulatory

229 Acutely isolating striatum from overlying neocortex normalized sEPSC frequency in G2019S mutants,

230 hronization between rIFC and primary sensory neocortex occurs in these frequency bands during inatten

231 netic stimulation in the caudate-putamen and neocortex of "histaminergic" axonal projections from the

232 (Thioflavin-S(+)) plaques from the temporal neocortex of 40 AD subjects with a symptom duration rang

233 e that signaling networks are altered in the neocortex of fragile X mice such that S6 phosphorylation

234 (but not mTOR) signaling is elevated in the neocortex of fragile X mice.

235 However, its presence in the neocortex of higher mammals is not well established.

236 The density of cells and neurons in the neocortex of many mammals varies across cortical areas a

237 for cell and neuron counts, we estimate that neocortex of one hemisphere contains 9.5 billion cells a

238 ocircuitry of frontoparietal networks in the neocortex of prosimian primates (Otolemur garnettii) usi

239 from multiple neurons in the hippocampus and neocortex of rats with chronic temporal lobe epilepsy to

240 time-lapse images of serotonin axons in the neocortex of the adult mouse.

241 Inhibitory interneurons in the neocortex often connect in a promiscuous and extensive f

242 neurons might help us to understand how the neocortex optimizes cost functions.

243 to EE, however, no changes were detected in neocortex or between Wt animals.

244 rhythm reflects internal processing with the neocortex or entrainment by external inputs from rhythmi

245 alterations to Abeta plaque pathology in the neocortex or hippocampus of APPSWE /PS1dE9 mice.

246 e studies have implicated Lewy bodies in the neocortex, others have pointed to alpha-synuclein pathol

247 ABAergic interneurons in the hippocampus and neocortex, particularly fast-spiking parvalbumin-positiv

248 For example, amyloid deposition in the neocortex precedes the spread of tau neurofibrillary tan

249 The evolutionary expansion of the neocortex primarily reflects increases in abundance and

250 originated independently from the mammalian neocortex, process visual numerosities.

251 ing system originating from the medulla, the neocortex provides dense anatomical projections that dir

252 de tracers.The major output cell type of the neocortex - pyramidal tract neurons (PTs) - send axonal

253 averaged beta power in primary somatosensory neocortex reflect a difference in the number of high-pow

254 Accordingly, the neocortex remained plastic even beyond the peak of its n

255 ell types and their wiring diagram in mature neocortex remains elusive.

256 tribution of GABAergic interneurons in mouse neocortex, resulting in abnormal accumulation in deep la

257 deletion from all postmitotic neurons in the neocortex results in lack of corpus callosum, anterior c

258 Intracellular recordings in the neocortex reveal not only the membrane potential of neur

259 Mosaic deletion of Sip1 in the neocortex reveals defects in axonal growth and in ipsila

260 The literature has long emphasized the neocortex's role in volitional processes.

261 orphology in 55 regions of the temporal lobe neocortex, selected from 13 patients who underwent epile

262 information, such as the hippocampus and the neocortex, share common cellular components and circuit

263 Neocortex showed significantly greater differential expr

264 ional IN variants in the hippocampus and the neocortex.SIGNIFICANCE STATEMENT Canonical interneuron (

265 In the human neocortex, single excitatory pyramidal cells can elicit

266 racted to measure, for the first time in the neocortex, specific changes in neuronal electrophysiolog

267 is based on similarity, and the six-layered neocortex structure could hardly be more dissimilar in a

268 lated network of ASD genes in the developing neocortex that are relatively intolerant to LoF mutation

269 However, birds lack a six-layered neocortex that enables primates with numerical competenc

270 es major ascending projections to the entire neocortex that have long been implicated in arousal, lea

271 ient gamma-frequency (30-80 Hz) responses in neocortex that show plasticity in a task-dependent manne

272 In the neocortex, the balance between activity and stability re

273 transferring hippocampal information to the neocortex, the exact cortical destinations and the physi

274 Thus, in human and monkey neocortex, the LFP reflects primarily inhibitory neuron

275 omponents in the development of the cerebral neocortex, the part of the brain involved in cognition a

276 on of the Project MindScope is to understand neocortex, the part of the mammalian brain that gives ri

277 ether the basic building blocks of the human neocortex, the pyramidal neurons, possess unique biophys

278 The ultrastructure of mouse neocortex therefore differs significantly comparing cryo

279 ories of NRG3 isoforms (classes I-IV) in the neocortex throughout the human lifespan, examined whethe

280 rapid, high-pressure freezing on adult mouse neocortex to quantify the extent to which these two fixa

281 e the radial and tangential expansion of the neocortex to the changes in the proliferative compartmen

282 ntorhinal cortex is a major gateway from the neocortex to the hippocampus.

283 The neocortex undergoes extensive developmental growth, but

284 s relay sensory and motor information to the neocortex using both single spikes and bursts; bursts pr

285 uronal progenitor cells of the embryonic rat neocortex using in utero electroporation.

286 identify cellular changes in human epileptic neocortex using transcriptional clustering.

287 are transferred from the hippocampus to the neocortex via the subiculum.

288 rat acute brain slices of the somatosensory neocortex, we found that theta burst neural activity pro

289 ight and electron microscopy data from mouse neocortex, we show that a surprisingly large fraction of

290 o both excitatory and inhibitory synapses in neocortex, where it is organized into nanoscale puncta t

291 y tubercle, nucleus accumbens, amygdala, and neocortex, whereas in spinal cord, pons, and medulla GPR

292 nduced folding in the otherwise smooth mouse neocortex, whereas the loss of Shh signaling decreased t

293 e brain, the Cajal-Retzius (CR) cells in the neocortex, which are known to be critical for cortical l

294 ubgroup of fate-restricted RGCs in the early neocortex, which generates only upper-layer neurons.

295 a large-scale dynamical model of the macaque neocortex, which is based on recently acquired directed-

296 rooted in the immensely expanded and folded neocortex, which reflects the expansion of neural progen

297 position of ribosomal proteins in developing neocortex, which we term the "neocortical ribosome signa

298 r (18)F-AV1451 uptake in wide regions of the neocortex, while older age was associated with increased

299 ds also revealed robust LRTCs throughout the neocortex with distinct scaling exponents in different f

300 involves temporal-locking of activity in the neocortex with that in the hippocampus.