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1 duplication and functional divergence (i.e. neofunctionalization).
2 tin molecular function due to redundancy and neofunctionalization.
3 with roles for both subfunctionalization and neofunctionalization.
4 to fully wired pathways upon duplication and neofunctionalization.
5 tion of these genes were preserved following neofunctionalization.
6 m the sterol pathway by gene duplication and neofunctionalization.
7 ying selection, limiting duplication and sub/neofunctionalization.
8 ne duplication event could allow for sub- or neofunctionalization.
9 t duplications that may have facilitated its neofunctionalization.
10 hich are associated with regulatory sub- and neofunctionalization.
11 ne transfer and gene duplication followed by neofunctionalization.
12 d gene complexity is regained via subsequent neofunctionalization.
13 process of subfunctionalization and possibly neofunctionalization.
14 nalization but decreasing the probability of neofunctionalization.
15 nderappreciated process underpinning protein neofunctionalization.
17 c acceleration of evolution that accompanied neofunctionalization after a duplication of the nonverte
19 Thus, our study highlights the importance of neofunctionalization and positive selection in the reten
20 ific gene duplication, subfunctionalization, neofunctionalization and pseudogenization of duplicated
21 ce occurs only in the presence of regulatory neofunctionalization and that in nonregulatory neofuncti
22 n and loss, by gene subfunctionalization and neofunctionalization, and by changes in protein targetin
23 embled from plant genes by gene duplication, neofunctionalization, and genome reorganization, rather
26 nalization) or emergence of novel functions (neofunctionalization) being the prevalent modes of evolu
27 city evolved in apicomplexan LDHs by classic neofunctionalization characterized by long-range epistas
28 1.7 million years (Myr) ago, followed by its neofunctionalization, created the current S locus assemb
30 igin of the betalain synthesis pathway, with neofunctionalization following gene duplications in the
35 ne duplication, supporting a common role for neofunctionalization in the long-term maintenance of gen
36 e relative roles of subfunctionalization and neofunctionalization in the retention of duplicate genes
37 hat LacD.1's adaptation represents a form of neofunctionalization in which duplication facilitated th
42 nvolved organisms by doubling gene dosage or neofunctionalization, it may also result in a simple div
43 This allowed us to test predictions of the neofunctionalization model for gene duplication and para
44 l events that result in a new gene function (neofunctionalization) necessitates that the other gene c
47 nant mutation, which led to either hyper- or neofunctionalization of a redundant homoeologous gene.
49 suggested that change in gene expression and neofunctionalization of capsaicin synthase have shaped c
50 Polyploidization and subsequent sub- and neofunctionalization of duplicated genes represent a maj
51 t regulation or function, duplication and/or neofunctionalization of genes that maintain plant homeos
52 ssion, and potential subfunctionalization or neofunctionalization of HYDIN2 early in the evolution of
55 and Lal2/SCRL likely occurred, together with neofunctionalization of Lal2/SCRL, and both haplotype gr
56 athways in C3 plants, through the regulatory neofunctionalization of preexisting genes and not throug
57 ing novel immunoglobulin-like receptors, and neofunctionalization of recently duplicated paralogs.
58 date of the underlying gene duplication and neofunctionalization of the ancestral diterpene synthase
59 gence of neural crest cells (NCCs), in which neofunctionalization of the duplicated genes are thought
60 n mammalian reproduction originated from the neofunctionalization of the vitamin B9-binding pocket of
62 ars, through duplication and specialization (neofunctionalization) of aminoacyl-tRNA synthetases and
63 at selection pressures can determine whether neofunctionalization or SUBF is the more likely evolutio
64 provide an experimental system for studying neofunctionalization or subfunctionalization of talin fo
66 y fates: one copy acquires a novel function (neofunctionalization), or each copy adopts part of the t
67 ven in large populations, the probability of neofunctionalization scales only with the square of the
69 ecies to quantify the roles of conservation, neofunctionalization, subfunctionalization, and speciali
70 ce that the Ohno's Duplication-Retention-Non/Neofunctionalization, subfunctionalization/duplication-d
72 t are not silenced may evolve new functions (neofunctionalization) that will alter the developmental
73 of ancestral functions among duplicates) or neofunctionalization (the acquisition of novel function)
74 of young duplicates in Drosophila shows that neofunctionalization, the gain of a novel function in on
75 e classical Ohno's Duplication-Retention-Non/Neofunctionalization theory, and the recently proposed a
76 in M. sexta lineage via gene duplication and neofunctionalization, whereas MsexD5 representing an alt
77 explain duplicate retention invokes sub- or neofunctionalization, whereas others focus on sharing of
78 SbCYP82D1.1 via gene duplication followed by neofunctionalization, whereby the ancestral F6H activity
79 , suggesting that the adaptation is owing to neofunctionalization, which we find to be explicable by
80 e transfers, gene duplication and subsequent neofunctionalization) will cause some genes to exhibit a
81 tic trafficking in plants was accompanied by neofunctionalization within the GBF family, whereas in o
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