ライフサイエンスコーパス: neopterin

1 ha-1-antitrypsin (AAT), myeloperoxidase, and neopterin.

2 ociated with baseline levels of beta-2 m and neopterin.

3 s/mL was associated with higher CSF level of neopterin.

4 .0001) over a 3-mo lag and moderately so for neopterin (13.97; P = 0.0074).

5 7,8-Dihydro-D-neopterin 2',3'-cyclic phosphate (H(2)N-cP) is the first

6 hydrolase that converts GTP to 7,8-dihydro-d-neopterin 2',3'-cyclic phosphate, the first intermediate

7 nd converts it to a mixture of 7,8-dihydro-D-neopterin 2'-monophosphate and 7,8-dihydro-d-neopterin 3

8 neopterin 2'-monophosphate and 7,8-dihydro-d-neopterin 3'-monophosphate.

9 , 1.2 x 10(6); biopterin, 1.0 x 10(6); d-(+)-neopterin, 3.1 x 10(5); isoxanthopterin, 2.8 x 10(5); se

10 by increases in C-reactive protein (6/8) and neopterin (4/8), which correlated with the onset of a fe

11 ndings indicate that high maternal levels of neopterin, a marker of cellular immune activation, durin

12 The aim of this study was to assess neopterin, a marker of interferon gamma (IFN-gamma) indu

13 Neopterin, a propane triol derivative of pterin, also bi

14 s of PEG-IFN and two immunologic surrogates, neopterin and 2'-5' oligoadenylate synthetase (OAS).

15 d, and there were greater decreases in serum neopterin and beta2-microglobulin levels.

16 ect inflammatory states, we also quantitated neopterin and C reactive protein.

17 Plasma neopterin and cytokines were measured by enzyme-linked i

18 rs revealed increases in median beta-2 m and neopterin and decreases in CD4% over this period and the

19 catabolite PA was positively associated with neopterin and KTR before and after treatment.

20 The immunologic surrogates, neopterin and OAS, were induced at all doses with a sust

21 ammation and macrophage activation, that is, neopterin and sCD14, which remained elevated in ART(+) p

22 ation of betaeta-2 microglobulin (beta-2 m), neopterin and suPAR soluble urokinase-type plasminogen a

23 een HIV-associated immune activation (plasma neopterin) and plasma selenium concentrations.

24 TNF receptor (R)II, soluble interleukin-2R, neopterin, and beta2-microglobulin (beta2M) were documen

25 ays post transmission) had CSF HIV RNA, WBC, neopterin, and CXCL10 concentrations similar to the chro

26 t of PP on lymphocyte subpopulations, plasma neopterin, and cytokines in renal transplant recipients

27 l fluid levels of tetrahydrobiopterin (BH4), neopterin, and homovanillic acid and low levels of tyros

28 C-reactive protein, white blood cell count, neopterin, and kynurenine:tryptophan collectively accoun

29 d erythrocyte sedimentation rate (ESR), IgG, neopterin, and TNF-alpha found in these patients suggest

30 CANCE: Our results suggest that beta-2 m and neopterin are useful tools for disease monitoring in bot

31 6-biopterin and pterin structural analogs of neopterin as well as glucose and creatinine.

32 ecrosis factor type II receptors (sTNFR-II), neopterin, beta2-microglobulin, or CD4 cell counts can b

33 inting, a synthetic polymer receptor for the neopterin cancer biomarker was devised and used as a rec

34 Urinary neopterin excretion is increased in patients with both p

35 o had infections during the study, increased neopterin excretion was noted for periods of up to 6 wee

36 tudy, and all were associated with increased neopterin excretion, which tended to be greater than tha

37 Renal NO and neopterin excretions were significantly heritable, as we

38 levels of soluble IL-2 receptor (sIL-2R) and neopterin, flow cytometry, and natural killer cell (NK)

39 ansformation of GTP to 7,8-dihydro-D-erythro-neopterin (H2neopterin), the precursor to the modified f

40 oxymethyldihydropterin, dihydroxanthopterin, neopterin, hydroxymethylpterin, xanthopterin, 6-formylpt

41 y based determination of 6 aromatic pterins (neopterin, hydroxymethylpterin, xanthopterin, 6-formylpt

42 post-PP lymphocyte subpopulations and plasma neopterin in 37, and cytokine plasma levels in 30, poten

43 feron gamma, interleukin 6, soluble CD14, or neopterin in cerebrospinal fluid.

44 Moreover, it determined neopterin in synthetic serum samples.

45 jection analysis conditions (FIA) determined neopterin in the concentration range of 0.15-2.5mM with

46 Plasma levels of inflammatory markers (neopterin, kynurenine:tryptophan ratio, and C-reactive p

47 mation and the kynurenine pathway, including neopterin, kynurenine:tryptophan ratio, C-reactive prote

48 The monocyte count and neopterin level were significantly higher in the autisti

49 ought to examine the association of maternal neopterin levels and KTRs during pregnancy with asthma i

50 ed the associations of maternal plasma total neopterin levels and KTRs in midpregnancy with asthma at

51 Neopterin levels and kynurenine/tryptophan ratios (KTRs)

52 With the progression to AIDS, neopterin levels increased in BkMG138.

53 valuated allergic versus nonallergic asthma, neopterin levels tended to be associated with nonallergi

54 Leukocyte counts and plasma neopterin levels were determined in autistic children an

55 atio, and CSF white blood cell counts (WBC), neopterin levels, and concentrations of chemokines CXCL1

56 strength) by CD4+ lymphocyte count and serum neopterin levels, serum beta 2-microglobulin levels, and

57 ildren of mothers in the highest quartile of neopterin levels, whereas the risk was similar in the 3

58 nocytes, and total leukocytes and for plasma neopterin levels.

59 re oral candidiasis (thrush) or fever; serum neopterin levels; serum beta 2-microglobulin levels; num

60 The accumulated pteridines included neopterin, monapterin, and hydroxymethylpterin; their re

61 dentified in some subjects with elevated CSF neopterin, monocyte chemotactic protein/CCL2, and interf

62 gically validated the measurement of urinary neopterin (NEO), a biomarker of cellular immune activati

63 cerebrospinal fluid levels of the following: neopterin; nitrite plus nitrate, a stable indicator of n

64 ococcus aureus DHNA (SaDHNA) in complex with neopterin (NP, an analog of DHNP) and with monapterin (M

65 ) HIV DNA was associated with plasma and CSF neopterin (p = 0.023) and with MRS markers of neuronal i

66 adjustment with binary logistic regression, neopterin (P<0.001), high-sensitivity C-reactive protein

67 phocytes:muL (P=0.001); and plasma levels of neopterin (P<;0.0001), soluble interleukin-1 receptor an

68 atients had significantly elevated levels of neopterin (P=.003) and kynurenine (P=.05) and a signific

69 dines: 6-biopterin, 6-hydroxymethylpterin, d-neopterin, pterin, isoxanthopterin, and xanthopterin, as

70 The levels of neopterin, pterine, xanthopterin, and pterin-6-carboxyli

71 controls (P = .0004) and correlated with CSF neopterin (r = 0.38; P = .0005), interferon gamma-induce

72 Urinary neopterin to creatinine ratios (UNCRs) were measured dai

73 ts is the conversion of GTP to 7,8-dihydro-d-neopterin triphosphate catalyzed by GTP cyclohydrolase I