ライフサイエンスコーパス: neovascularization

1 in murine muscle tissue during postischemic neovascularization.

2 l development and the pathobiology of ocular neovascularization.

3 a unique risk for the development of GA and neovascularization.

4 ry cell infiltration, tissue destruction and neovascularization.

5 sit, visual acuity was 20/20 with no sign of neovascularization.

6 tric oxide (NO) in macrophages and choroidal neovascularization.

7 el therapeutic target for reducing choroidal neovascularization.

8 rgeting the tumor endothelium to block tumor neovascularization.

9 Intrinsic flow was strongest in type 2 neovascularization.

10 sufficient to inhibit scaffold formation and neovascularization.

11 UM) of ex vivo cleared whole brains to track neovascularization.

12 ceptors and can be associated with choroidal neovascularization.

13 nges and potentially of subsequent choroidal neovascularization.

14 tarved Vldlr(-/-) photoreceptors, leading to neovascularization.

15 growth through decreasing proliferation, and neovascularization.

16 edures primarily targeting macular edema and neovascularization.

17 pothesized that HDL rescue diabetes-impaired neovascularization.

18 nd discover novel drugs that inhibit retinal neovascularization.

19 d retinal endothelial cell proliferation and neovascularization.

20 nduced retinopathy and laser-induced choroid neovascularization.

21 opmental angiogenesis or during inflammatory neovascularization.

22 y fibrous membrane formation after choroidal neovascularization.

23 VEGF in the retina of mice causes subretinal neovascularization.

24 and that this scaffold limits the extent of neovascularization.

25 splays pathologic roles in tumorigenesis and neovascularization.

26 in diabetic maculapathy and diabetic retinal neovascularization.

27 l cell proliferation, tip cell formation and neovascularization.

28 e no reports of neovascular glaucoma or iris neovascularization.

29 peripheral vasculitis, and (4) leakage from neovascularization.

30 lular damage and suppress harmful pathologic neovascularization.

31 ss, vitrectomy, DME development, and retinal neovascularization.

32 nt importance in the pathogenesis of retinal neovascularization.

33 ting plays an intricate role in postischemic neovascularization.

34 cts for their therapeutic utility in retinal neovascularization.

35 ative macrophage activation and pathological neovascularization.

36 endent transcription factor, in inflammatory neovascularization.

37 ration: 15 years) with no evidence of active neovascularization.

38 implicated in the pathogenesis of choroidal neovascularization.

39 ited the capacity for cell proliferation and neovascularization.

40 nduced retinopathy and laser-induced choroid neovascularization.

41 rmal and with macular degeneration/choroidal neovascularization.

42 absence, and high-grade CE, the presence of neovascularization.

43 ticle deposition occurred in areas of plaque neovascularization.

44 en-induced uveitis and laser-induced retinal neovascularization.

45 ne editing or 2'-O-ribose-methylation during neovascularization.

46 ive strategy for treating pathologic retinal neovascularization.

47 showed large intrahepatic tumors with active neovascularization.

48 as vascular malformations, nonperfusion, and neovascularization.

49 wth factor (VEGF) is a powerful regulator of neovascularization.

50 mbination with exogenous Ang1, for effective neovascularization.

51 The underlying mechanism may be involved in neovascularization.

52 The corneas healed with scar formation and neovascularization.

53 F therapy, and may be associated with type 3 neovascularization.

54 pathogenic role in retinal inflammation and neovascularization.

55 s [100%]) and stage 3+ ROP with nonconfluent neovascularization (2/14 infants [14.3%]) recurred only

56 Corneal neovascularization, a frequent complication of corneal h

57 Current treatments for choroidal neovascularization, a major cause of blindness for patie

58 c insult typically leads to aberrant retinal neovascularization, a major cause of blindness.

59 nt epithelium (RPE) abnormalities, choroidal neovascularization, acquired vitelliform lesions (AVLs),

60 Biomarker maps of neovascularization activity (microvessel radius, microve

61 onance (MR) imaging of oxygen metabolism and neovascularization activity for grading and characteriza

62 atory infiltrate, fibrotic degeneration, and neovascularization after 6 hours and 10 hours of CI.

63 ormation in vitro and in vivo during retinal neovascularization after induction of VEGF expression.

64 after regression of laser-induced choroidal neovascularization and a decrease in mesenchymal retinal

65 activating a fetal gene programme to promote neovascularization and cardiomyogenesis.

66 evealed the formation of an epidermis layer, neovascularization and cell proliferation.

67 immunohistochemistry revealed abundant lung neovascularization and cellular proliferation in PE that

68 nal lesions can be associated with choroidal neovascularization and central serous chorioretinopathy

69 To determine the effect of Wnt10b on neovascularization and fibrosis, we generated a mouse li

70 In zones 2 and 3, neovascularization and geographic atrophy (GA) were pres

71 ls in gliomas as a pivotal modifier of tumor neovascularization and immunosuppression, strengthening

72 henotype and their pathogenic roles in tumor neovascularization and immunosuppression.Significance: T

73 Disordered neovascularization and impaired wound healing are import

74 , IL-6, IL-8, IL-1beta and MCP-1, leading to neovascularization and increased resistance to Temozolom

75 as a key player in the development of ocular neovascularization and indicate a fundamental role of TG

76 ptor played a permissive role in suppressing neovascularization and inflammation in vivo Comparing AG

77 larization (CNV), mimicking hypoxia-mediated neovascularization and inflammatory mediated angiogenesi

78 Ischemia-induced hypoxia elicits retinal neovascularization and is a major component of several b

79 ing strategy with rodent models of choroidal neovascularization and iterative compound design to iden

80 Ultrasonography showed decreased neovascularization and lesion skin depth in the MABp1 gr

81 identify HSV-1 SNPs associated with corneal neovascularization and mean peak percentage weight loss

82 Inhibition of neovascularization and modulation of the production of I

83 visual acuity, regression or development of neovascularization and need for retreatment sessions and

84 oidal vasculopathy is a variant of choroidal neovascularization and neovascular age related macular d

85 ing Sema3e promoted disoriented pathological neovascularization and partially abolished the inhibitor

86 etic retinopathy, OCT angiography can detect neovascularization and quantify ischemia.

87 s increased blood vessel density, suggesting neovascularization and rare lymphatic vessels suggestive

88 ion of expression of alpha SMA and TGF beta, neovascularization and re-epithelialization.

89 bitor substantially reduced the pathological neovascularization and rescued visual function in Vldlr(

90 and monocyte recruitment and delays thrombus neovascularization and resolution.

91 esses to help clear tumors by blunting tumor neovascularization and restoring immunosurveillance.

92 y be effective targets/tools for therapeutic neovascularization and targeted cell delivery.

93 -mediated leukostasis, retinal ischemia, and neovascularization and their contribution to pathologica

94 C) to the ischemic tissues is a key event in neovascularization and tissue regeneration.

95 y which to facilitate EPC homing and promote neovascularization and tissue repair.

96 helial-like cell-lined structures to support neovascularization and to fuel solid tumors is a hallmar

97 luorescein angiography (lesion type, area of neovascularization and total lesion, retinal angiomatous

98 for CATT specified that eyes have choroidal neovascularization and visual acuity between 20/25 and 2

99 nucleotide polymorphisms (SNPs) involved in neovascularization and weight loss.

100 ignaling inhibition, and pathological ocular neovascularization and wound healing, as well.

101 in 6 eyes of 3 patients who had extraretinal neovascularization and/or peripheral avascular retina on

102 fold degradation, fibrous encapsulation, and neovascularization) and a mean composite score.

103 ANG also promotes neovascularization, and can induce hemorrhage and encour

104 with vascular adhesion molecule expression, neovascularization, and cells positive for CD45, conside

105 on stump healing, perfusion, adductor muscle neovascularization, and decreased muscle fiber damage.

106 overexpress VEGF or have signs of mesenteric neovascularization, and developed less-severe forms of p

107 including corneal opacification, ulceration, neovascularization, and ectasia.

108 inal pigment epithelium abnormalities, AVLs, neovascularization, and GA occurred at a frequency of 47

109 achment, 2 patients showed only intraretinal neovascularization, and in 2 patients flow was limited t

110 ipoproteins (HDLs) enhance ischemia-mediated neovascularization, and mounting evidence suggests HDL h

111 in recovering cardiac function, stimulating neovascularization, and promoting myocardial remodeling.

112 us strain WR results in blepharitis, corneal neovascularization, and stromal keratitis.

113 ed in areas previously occupied by choroidal neovascularization, and the other 5 eyes had atrophy pri

114 may be involved in corneal wound healing and neovascularization, and thus, may serve as targets for p

115 h factor antagonists also suppress choroidal neovascularization, and transgenic expression of VEGF in

116 induced retinopathy, laser-induced choroidal neovascularization, and transgenic mouse models with def

117 re elevated in patients with retinal or iris neovascularization, and VEGF-specific antagonists marked

118 ighly enhanced at the early stage of retinal neovascularization, and we found simultaneous reduction

119 entation, and vascularity; incidence of iris neovascularization; and radiation-related complications.

120 ug assay, which mimics ischemic/inflammatory neovascularization, angiogenesis was dramatically upregu

121 Inflammation and intraplaque neovascularization are acknowledged to be 2 features of

122 Vascular permeability and neovascularization are implicated in many diseases inclu

123 Inflammation and intraplaque neovascularization are not systematically associated in

124 of greatest significance were appearance of neovascularization as APROP (P = 0.006), extended durati

125 rs with the presence of subretinal/choroidal neovascularization as indicated by International Classif

126 wn to promote cell proliferation, leading to neovascularization as well as neuroprotection in mammals

127 h deficient or spontaneous retinal/choroidal neovascularization, as well as models with induced corne

128 us) and vascularized PEDs (type 1 and type 3 neovascularization) associated with drusen and a thin ch

129 C3 were associated with specific features of neovascularization at the time patients were enrolled in

130 (+) cells in immunodeficient mice, promoting neovascularization (at 28 days, post-I-R) and lower inte

131 This may be related to decreased neovascularization, because decreased CD31 staining, ind

132 than their mother, despite lacking choroidal neovascularization, because of the extent of photorecept

133 alysis detected an epistatic interaction for neovascularization between a segment of the unique long

134 nous glucose administration and reduction of neovascularization by argon laser pan-retinal photocoagu

135 sfully engrafted with histologic evidence of neovascularization by day 4.

136 ells to brain endothelial cells and enhanced neovascularization by inducing the secretion of IL8 and

137 In this study, we imaged neovascularization by label-free dark-field microscopy o

138 y lead to methods of regulating pathological neovascularization by specifically targeting endothelial

139 age-related macular degeneration, choroidal neovascularization can be observed without the obscurati

140 ipheral retinal pathologies captured include neovascularization, capillary nonperfusion, and skip are

141 almia, retinal dysplasia, keratitis, corneal neovascularization, cataracts, and calcification.

142 ion MR imaging-derived oxygen metabolism and neovascularization characterization may be useful for gr

143 between all rare pLoF variants and choroidal neovascularization (CNV) (OR, 1.34; 95% CI, 1.04-1.73; P

144 ng for early detection of incident choroidal neovascularization (CNV) among patients with age-related

145 Choroidal neovascularization (CNV) and capillary dilations were qu

146 lemia, worse visual acuity, larger choroidal neovascularization (CNV) area, retinal angiomatous proli

147 se mice develop significantly less choroidal neovascularization (CNV) compared to wild-type controls

148 s over time and their influence on choroidal neovascularization (CNV) development.

149 ography (OCTA) in the detection of choroidal neovascularization (CNV) in age-related macular degenera

150 s and natural history of quiescent choroidal neovascularization (CNV) in geographic atrophy (GA) seco

151 ema (DME), retinal vein occlusion, choroidal neovascularization (CNV) in high myopia, and other cause

152 Choroidal neovascularization (CNV) is a major cause of vision loss

153 Eyes with subfoveal choroidal neovascularization (CNV) lesions had a lower growth rate

154 by increased size of laser-induced choroidal neovascularization (CNV) lesions.

155 of 7KCh-exposed microglia promoted choroidal neovascularization (CNV) relative to control microglia i

156 d angiographic and OCT evidence of choroidal neovascularization (CNV) secondary to age-related macula

157 s, angiographic total lesion size, choroidal neovascularization (CNV) size, and optical coherence tom

158 5% mean reduction from baseline in choroidal neovascularization (CNV) size.

159 In contrast to the choroidal neovascularization (CNV) subtype, the genetic risk facto

160 ctor (TNF)-alpha has been found in choroidal neovascularization (CNV) surgically removed from patient

161 prominent in patients with classic choroidal neovascularization (CNV) than those with occult CNV (P <

162 Choroidal neovascularization (CNV) was manually segmented on OCTA

163 The molecular pathogenesis of choroidal neovascularization (CNV), an angiogenic process that cri

164 retinas treated with laser-induced choroidal neovascularization (CNV), bright white-light exposure, a

165 wth of choroidal blood vessels, or choroidal neovascularization (CNV), is a hallmark of the neovascul

166 etinopathy (OIR) and laser-induced choroidal neovascularization (CNV), mimicking hypoxia-mediated neo

167 eration (RAP) lesions, and classic choroidal neovascularization (CNV).

168 dot syndrome (MEWDS) who developed choroidal neovascularization (CNV).

169 sible blindness and manifests with choroidal neovascularization (CNV).

170 neration (AMD) is characterized by choroidal neovascularization (CNV).

171 types; geographic atrophy (GA) and choroidal neovascularization (CNV).

172 etinal pigment epithelial changes; choroidal neovascularization (CNV); atrophy; and hypoautofluoresce

173 nterval [CI], 53-442), followed by choroidal neovascularization (CNV; OR, 90; 95% CI, 26-310), interm

174 rom pathologic RPE detachments and choroidal neovascularizations (CNVs).

175 iography may underestimate the prevalence of neovascularization compared to OCT angiography.

176 expressing HLEKs elicited a lesser degree of neovascularization compared with controls.

177 ha-OE mice had also exacerbated TNBS-induced neovascularization compared with TNBS-exposed wild-type

178 , SLN expression, mitochondrial content, and neovascularization, compared with WT mice.

179 is was found, 3 patients showed intraretinal neovascularization connected with a pigment epithelial d

180 Swept-source OCTA identified type 1 neovascularization corresponding to ICGA plaques in asym

181 AMD, and SS OCTA revealed unambiguous type 1 neovascularization corresponding to the plaques in all 3

182 gene was previously identified as a corneal neovascularization determinant, validating the vQTLmap m

183 ed cardiomyocyte apoptosis, enhanced infarct neovascularization, diminished cardiac hypertrophy and f

184 y to prevent further vision loss and retinal neovascularization due to extensive retinal ischemia.

185 The presence of intraplaque neovascularization during contrast-enhanced ultrasound w

186 Two eyes were associated with a type 3 neovascularization eccentric to PEVAC.

187 features expressed therein may also apply to neovascularization elsewhere in the body, such as in tum

188 Here we show that unlike neovascularization, endothelial Akt signalling in establ

189 In vitro models that mimic in vivo tumor neovascularization facilitate exploration of this role.

190 n in macular disease includes type 2 macular neovascularization, fibrosis, exudation, vitelliform mat

191 Secondary outcome measures were corneal neovascularization following hydrops and complications f

192 significantly decreases pathological retinal neovascularization following OIR.

193 association of retinal hypoxia with retinal neovascularization has been recognized for decades, caus

194 the correlate of protection against corneal neovascularization, HSV-1 shedding, and latency through

195 The vQTLmap analysis using Random Forest for neovascularization identified phenotypically meaningful

196 ularization in 3 eyes and inactive choroidal neovascularization in 1 eye.

197 fficiency in 2.8% of eyes; non-AMD choroidal neovascularization in 2.3% of eyes; retinitis pigmentosa

198 low signal corresponding to active choroidal neovascularization in 3 eyes and inactive choroidal neov

199 ngiography demonstrated specific features of neovascularization in 5 out of 17 eyes (29%) with suspec

200 itiation and growth of spontaneous choroidal neovascularization in a mouse model, and the combination

201 more, this scaffold laden with EPCs promoted neovascularization in an animal model of hind limb ische

202 001 effectively protected against pathologic neovascularization in both oxygen-induced retinopathy an

203 oducts of cytochrome P450 oxidase 2C promote neovascularization in both the retina and choroid, which

204 ation affects organ function and therapeutic neovascularization in diabetes mellitus.

205 regulatory roles in regulating pathological neovascularization in eye diseases.

206 ecific antagonists markedly suppress retinal neovascularization in mice and primates with ischemic re

207 activation and reduces vascular leakage and neovascularization in mouse models.

208 Laser-induced neovascularization in Nnt-4(-/-) mice did not differ to

209 multimodal imaging, helps diagnose choroidal neovascularization in patients with Malattia Leventinese

210 genesis inhibitor Endostar on carotid plaque neovascularization in patients with non-small cell lung

211 edly attenuates healing after MI by reducing neovascularization in peri-infarct zones.

212 o assays, low concentrations of NaBu induced neovascularization in sponge implants in mice, evidenced

213 e assessment of inflammation and intraplaque neovascularization in the carotid plaque of symptomatic

214 teractions that are essential for pathologic neovascularization in the eye.

215 Cs significantly improved limb perfusion and neovascularization in the murine ischemic hindlimb.

216 glycolytic enzymes and reduces pathological neovascularization in the OIR mice.

217 acity, anterior chamber reaction, or stromal neovascularization in the patients' right eyes.

218 eling and maturation concurrently increasing neovascularization in the periurethral tissue.

219 ence tomography angiography did not identify neovascularization in the remaining 8 eyes.

220 ed severely disorganized collagen fibers and neovascularization in the tendon midsubstance.

221 l cell proliferation, tip cell formation and neovascularization in vivo.

222 lary network formation in Matrigel plugs and neovascularization in vivo.

223 and podocyte-derived VEGF is associated with neovascularization in wet age-related macular degenerati

224 Neovascularization incidence also was increased with ret

225 Corneal neovascularization increases the risk of T cell-mediated

226 HM with the presence of subretinal/choroidal neovascularization indicated by the ICD-9-CM diagnosis o

227 oietin-1 (Ang1) contribute differentially to neovascularization induced by nitric oxide (NO)-mediated

228 ma stem cells (GSCs) are implicated in tumor neovascularization, invasiveness, and therapeutic resist

229 Ocular neovascularization is a leading cause of blindness in pr

230 n treating uveitis and ocular diseases where neovascularization is a significant part of the patholog

231 However, aberrant neovascularization is an essential pathogenic mechanism

232 A neovascularization is commonly observed in the vicinity

233 These findings revisit the model where neovascularization is considered to happen concomitant w

234 Corneal neovascularization is critical for the progression of bl

235 g involved in miR93-mediated ischemic muscle neovascularization is not clear.

236 Ocular neovascularization is strongly associated with inflammat

237 ers of cell proliferation (Ki-67), decreased neovascularization (laminin and alphaSMA), in addition t

238 Pigmented mice with laser-induced choroidal neovascularization lesions (n = 7 eyes) were also imaged

239 oth area and number of spontaneous choroidal neovascularization lesions.

240 le for TLR2 in the pathogenesis of choroidal neovascularization, likely by promoting inflammation of

241 Choroidal neovascularization location as well as retinal pigment e

242 ogenous VEGF expression as a therapeutic for neovascularization may not be successful.

243 n eyes with treatment-naive myopic choroidal neovascularization (mCNV) in the United States.

244 ntify the size and vessel density of macular neovascularization (MNV) using optical coherence tomogra

245 itment in zebrafish and observed compromised neovascularization, neutrophil clearance, cardiomyocyte

246 a enhanced immune cell dynamics and promoted neovascularization, neutrophil clearance, cardiomyocyte

247 umour engraftment permits dynamic imaging of neovascularization, niche partitioning of tumour-propaga

248 y the ICD-9-CM diagnosis of "362.16: Retinal Neovascularization NOS." RESULTS: The estimated diopter-

249 l Modification diagnosis of "362.16: Retinal Neovascularization NOS." Type of initial treatment for m

250 vasculature (phase 1) followed by subsequent neovascularization (NV) (phase 2).

251 lyze the long-term growth patterns of type 1 neovascularization (NV) in eyes with age-related macular

252 without evident signs of active or regressed neovascularization [NV] at baseline), CFP may be suffici

253 Consequently, retinal and vitreal neovascularization occurs, a scenario that leads to reti

254 a promising effective method in reduction of neovascularization of a ROP rat model.

255 yestradiol (2-ME) nanoemulsion in regressing neovascularization of a ROP rat model.

256 n it significantly reduces both the size and neovascularization of CAG myeloma tumor xenografts.

257 Emerging role of dopamine in neovascularization of pheochromocytoma and paraganglioma

258 a recovery phenotype characterized by robust neovascularization of the injury zone, less myofibroblas

259 en growth, formation of GA, and formation of neovascularization offers an opportunity to study therap

260 ions of ARMS2 and CFH with type of choroidal neovascularization on fluorescein angiography were not c

261 yperoxia exposure and later ischemia-induced neovascularization on supplemental oxygen withdrawal.

262 nted accelerated wound healing and increased neovascularization on tissue injury as monitored by opti

263 e possibility that the bioelectric impact of neovascularization on vascular function is a previously

264 thy, and did not have a history of choroidal neovascularization or photodynamic therapy.

265 rrhage, retinal detachment, anterior segment neovascularization, or neovascular glaucoma.

266 ction as age </=25 years (P = .017), corneal neovascularization (P = .001), donor trephination size >

267 hologic features, including graft-associated neovascularization, postherpetic keratitis scarring, lip

268 literation followed by abnormal intravitreal neovascularization predisposing patients to retinal deta

269 nts with treatment-naive subfoveal choroidal neovascularization receiving intravitreal ranibizumab or

270 following sites: stage 3+ ROP with confluent neovascularization recurred both at the advancing edge a

271 was applied using standard parameters, until neovascularization regressed or complete retinal coverag

272 eyes with retinal vasculitis and the rate of neovascularization relapse in ischemic vasculitis.

273 a dome-shaped macula in 1 (6%), a choroidal neovascularization-related subretinal scar in 3 (19%), a

274 r, and no recurrence of type 1 ROP or severe neovascularization requiring additional treatment within

275 cell-derived growth factor-1 (SDF1) promotes neovascularization, resulting in faster re-epithelializa

276 nts, aged >/=50 years, with active choroidal neovascularization secondary to AMD.

277 (32%) had neovascular AMD and 1 eye (3%) had neovascularization secondary to pseudoxanthoma elasticum

278 ative intraretinal cystic changes, choroidal neovascularization, serous retinal elevations mimicking

279 ptor degeneration, and exaggerated choroidal neovascularization similar to AMD.

280 Neovascularization SNPs were identified in the ICP4, VHS

281 cuity, on average, at detection of choroidal neovascularization than do individuals using standard ca

282 OCT has greater diagnostic value for type 1 neovascularization than previously thought and that dye

283 The mother had choroidal neovascularization that was treated with bevacizumab.

284 Despite robust neovascularization, the microcirculation formed by regen

285 With extensive neovascularization, this voltage input is substantial an

286 eart, affecting the amplitude of therapeutic neovascularization via rAAV.Tbeta4 in a translational la

287 Presence of preoperative corneal or graft neovascularization was an indicator of a high risk of gr

288 TNBS-induced neovascularization was attenuated in HIF-1alpha-KO mice,

289 Besides, corneal neovascularization was much more extended in SLPI and Bu

290 Corneal neovascularization was present at the time of PK in 44.6

291 cular specimens and rodent models of retinal neovascularization, we discovered that pathological neov

292 Activation of microglia and neovascularization were also detected in the MPS IIIB re

293 Occurrence of GA and neovascularization were important determinants of final

294 dlr (-/-) ) mice with spontaneous subretinal neovascularization, whereas a RORalpha agonist worsened

295 uded plus disease (20/20 infants [100%]) and neovascularization, which appeared at the following site

296 herapeutic agents in inhibiting pathological neovascularization with a range of clinical applications

297 ammatory response that coherently stimulates neovascularization within the granulation tissue during

298 t anti-VEGF agents can suppress uncontrolled neovascularization without completely blocking the vascu

299 OCTA is useful to detect neovascularization without injecting a contrast product,

300 ee eyes of 25 patients were included (type 2 neovascularization x3; fibrosis x4; exudation x10; hemor