ライフサイエンスコーパス: nephritogenic

1 indicative of the presence of non-anti-dsDNA nephritogenic Ab.

2 on had no effect on either the cryogenic and nephritogenic activities of 6-19 IgG3 rheumatoid factor,

3 gens inciting alloimmunity and as targets of nephritogenic alloantibodies in APTN.

4 -reactivity with alpha-actinin characterizes nephritogenic anti-dsDNA Abs in humans with lupus as wel

5 Murine nephritogenic anti-dsDNA antibodies have been shown to c

6 ionships among treatment effect, circulating nephritogenic anti-phospholipase A2 receptor (anti-PLA2R

7 complex class II-restricted, cognate help to nephritogenic antinuclear autoantibody-producing B cells

8 re injected with lipopolysaccharide (LPS) or nephritogenic antisera developed markedly less proteinur

9 IgG2a, IgG2b, and IgG3 being the isotypes of nephritogenic autoantibodies induced in the lupus mice.

10 ifferentially regulate two different sets of nephritogenic autoantibody responses.

11 usly localized the critical autoepitopes for nephritogenic autoantibody-inducing Th cells in the core

12 challenge suggests that humoral immunity to nephritogenic basement membrane epitopes targeted in sys

13 Moreover, IL-15 decreases the induction of a nephritogenic chemokine, MCP-1, that attracts leukocytes

14 icated by greatly reduced indices of injury (nephritogenic cytokines, tubular apoptosis, and prolifer

15 esized and rats were immunized to define the nephritogenic epitope.

16 d from proteinuric rats with HN induced with nephritogenic Fx1A.

17 As a result, nephritogenic immune complexes form in the circulation a

18 ally mediated inhibition of the formation of nephritogenic immune complexes that could be used as a d

19 ls were most important in the development of nephritogenic immune complexes.

20 bition during ongoing disease aggravated the nephritogenic immune response and disease symptoms.

21 KK2 inhibition can suppress the induction of nephritogenic immune responses in vivo, it may aggravate

22 of anti-IL-6 after establishment of adaptive nephritogenic immunity was sufficient to aggravate NTN w

23 Thus, Crry is a key nephritogenic immunogen in Fx1A.

24 ease in MHC haplotypes capable of generating nephritogenic lymphocytes with special T cell repertoire

25 These results demonstrate that the nephritogenic mAb 5-1-6 identifies the extracellular dom

26 Importantly, a panel of nephritogenic mAbs had significantly higher affinity for

27 Furthermore, nephritogenic monoclonal IgG2 (clone H147) derived from

28 by nasal insufflation of the immunodominant nephritogenic MPO peptide (MPO409-428) to attenuate this

29 I MHC (I-Ed/I-Ad) determinants, and selected nephritogenic MR clones preferentially recognize renal A

30 In vitro proliferative responses of nephritogenic MR clones reveal predominant reactivity to

31 CA in patients with acute vasculitis and the nephritogenic murine T cell MPO epitope emphasizes the c

32 Rats were immunized with nephritogenic peptide that was derived from the amino te

33 Unexpectedly, the most nephritogenic peptide, pCB, derived from Clostridium bot

34 yoglobulinemia, but the features that confer nephritogenic potential are not completely understood.

35 factor, terminal sialylation attenuated the nephritogenic potential of 6-19 IgG3 by limiting its cry

36 similar to that used in the rat to show the nephritogenic potential of heterologous anti-laminin and

37 in relation to cryoglobulin activity, to the nephritogenic potential of IgG3 antibodies.

38 y T cells and thereby, unleashes preexisting nephritogenic responses.

39 e, due to an enhanced immune response to the nephritogenic sheep IgG.

40 cytes or anti-alpha3(IV) NC1 antibodies from nephritogenic strains transfer disease to syngeneic reci

41 here is a classical association of so-called nephritogenic strains with the opacity factor-positive p

42 flammation is probably induced directly by a nephritogenic streptococcal protein in poststreptococcal

43 In this study, we describe a CD4+ nephritogenic T cell clone that, unlike a sister clone w

44 ern with IL-4 and IL-10 expression, although nephritogenic T cell clones also express IFN-gamma.

45 b to diverse GBM Ags was induced by a single nephritogenic T cell epitope in a rat model.

46 demonstrated in our rat model that a single nephritogenic T cell epitope pCol28-40 of Col4alpha3NC1

47 verse native GBM Ags was induced by a single nephritogenic T cell epitope.

48 These data suggest that the nephritogenic T cell response in chronic graft-vs-host d

49 Kidney dendritic cells (DCs) regulate nephritogenic T cell responses.

50 protective Th2-related IgG antibodies versus nephritogenic Th1-related IgG autoantibodies.

51 The systemic and renal nephritogenic TH17 immune response decreased markedly in