ライフサイエンスコーパス: nerve regeneration

1 continuing and essential role in successful nerve regeneration.

2 eutrophils, platelets, and VEGF-A in corneal nerve regeneration.

3 iation states required to support peripheral nerve regeneration.

4 transcriptional program and is critical for nerve regeneration.

5 platelet infiltration and >50% reduction in nerve regeneration.

6 nal alterations observed in CH neurons after nerve regeneration.

7 use cutaneous CH neurons following saphenous nerve regeneration.

8 ightly, but significantly, compromised optic nerve regeneration.

9 e fiber regeneration may account for altered nerve regeneration.

10 s as a key negative regulator of adult optic nerve regeneration.

11 valent requirement of active CRMP2 for optic nerve regeneration.

12 transporting protein, facilitates olfactory nerve regeneration.

13 al factors seem to play a role in successful nerve regeneration.

14 mice, suggesting apoE facilitates olfactory nerve regeneration.

15 nt of mRNAs related to protein synthesis and nerve regeneration.

16 ggested, so we tested its role in peripheral nerve regeneration.

17 at two differentiation stages on peripheral nerve regeneration.

18 role of RAGE in these distinct cell types on nerve regeneration.

19 omponent of the myelin-derived inhibition of nerve regeneration.

20 ing chemorepellant growth cone responses and nerve regeneration.

21 binds to the nerve cell surface and inhibits nerve regeneration.

22 a potential therapeutic target for promoting nerve regeneration.

23 hose genes induced during successful sciatic nerve regeneration.

24 yelination is a critical step for functional nerve regeneration.

25 anoreceptor and sensory fiber function after nerve regeneration.

26 s for cancer, pathological angiogenesis, and nerve regeneration.

27 y be a significant contributor to successful nerve regeneration.

28 nerve compared with sham counterparts during nerve regeneration.

29 chwann cells, whose presence is critical for nerve regeneration.

30 eprogram Schwann cells to promote peripheral nerve regeneration.

31 formation of neuromuscular junctions during nerve regeneration.

32 ests that galanin plays a role in peripheral nerve regeneration.

33 expression appears independent of peripheral nerve regeneration.

34 bution of MAP7 to neurological disorders and nerve regeneration.

35 d, replicating previous studies of olfactory nerve regeneration.

36 lly using such polymers to stimulate in vivo nerve regeneration.

37 licated for the first time in the process of nerve regeneration.

38 ately induced with gRICH68 mRNA during optic nerve regeneration.

39 ult during tumorigenesis, wound healing, and nerve regeneration.

40 induced in the goldfish retina during optic nerve regeneration.

41 chwann cells, whose presence is critical for nerve regeneration.

42 s surgically repaired to facilitate accurate nerve regeneration.

43 ed peripheral nerve repair profoundly limits nerve regeneration.

44 rylation of CRMP2 in RGCs and improved optic nerve regeneration.

45 duit with designer structures for peripheral nerve regeneration.

46 physiological pain, neuronal cell death, and nerve regeneration.

47 naptic communication, synaptic strength, and nerve regeneration.

48 3 activity show markedly accelerated sciatic nerve regeneration.

49 factor required for Schwann cells to support nerve regeneration.

50 well as JUN, all of which are essential for nerve regeneration.

51 ed proteins have been shown to contribute to nerve regeneration.

52 d cells for beta(1, 3)-glucan-elicited optic nerve regeneration.

53 ore potential targets for promoting auditory nerve regeneration.

54 proline/glutamine rich) that attenuate optic nerve regeneration.

55 europoietic cytokine receptors in peripheral nerve regeneration.

56 to these disorders, since they could promote nerve regeneration.

57 d at maximum speeds comparable to peripheral nerve regeneration.

58 homophilic adhesion molecule and involved in nerve regeneration.

59 tion on injuries, aiming to allow peripheral nerve regeneration.

60 navigation during embryonic development and nerve regeneration.

61 biological processes such as myelination and nerve regeneration.

62 pobec2b were found to be essential for optic nerve regeneration.

63 o a progenitor-like state, in which they aid nerve regeneration.

64 antibody exhibited >80% reduction in corneal nerve regeneration.

65 in the successful regeneration of peripheral nerves regeneration.

66 protocols designed to facilitate or restrict nerve regeneration: 1) ligation, in which transected axo

67 For successful nerve regeneration, a coordinated shift in gene expressi

68 gnificantly improved the distance of sensory nerve regeneration achieved after nerve crush injury com

69 ncoding galanin exhibit decreased peripheral nerve regeneration after a lesion.

70 n of IGF-1 in skeletal muscle enhances motor nerve regeneration after a nerve crush injury.

71 eceptor with Herceptin unexpectedly enhances nerve regeneration after acute and delayed nerve repair.

72 nvestigated the process of axon regrowth and nerve regeneration after complete transection of the Oct

73 Peripheral nerve regeneration after injury is dependent upon implem

74 factors (FGFs) are key players in peripheral nerve regeneration after injury.

75 al stimulation may be effective in promoting nerve regeneration after injury.

76 ma7a in naive corneas and corneas undergoing nerve regeneration after lamellar corneal surgery in thy

77 significantly improve the pace and degree of nerve regeneration after nerve injury and hindlimb trans

78 could be an important step towards promoting nerve regeneration after stroke or spinal cord injury.

79 a implanted pellets showed increased corneal nerve regeneration after superficial injury compared wit

80 outgrowth during development and peripheral nerve regeneration after trauma, and hence to the develo

81 data suggest a new mechanism for peripheral nerve regeneration along a tubulated gap.

82 nophilins can regulate neuronal survival and nerve regeneration although the molecular mechanisms are

83 They play a crucial role in nerve regeneration and can be used clinically in the rep

84 ly important in regulating cell migration in nerve regeneration and cortical development.

85 play a role in dedifferentiation as well as nerve regeneration and degeneration.

86 , the neurite outgrowth factor that inhibits nerve regeneration and destabilizes neuromuscular juncti

87 eneration studies may propel improvements in nerve regeneration and draw critical parallels to mechan

88 and blocking of NKG2D also inhibited corneal nerve regeneration and epithelial healing (P < 0.01).

89 600 mM M6P to the nerve repair site enhances nerve regeneration and functional recovery in the early

90 LY117018 may markedly accelerate peripheral nerve regeneration and functional recovery through activ

91 veloping therapeutic strategies that improve nerve regeneration and functional recovery.

92 ction in retinal ganglion cells during optic nerve regeneration and in a subset of Muller glia that p

93 esults suggest that ninjurin plays a role in nerve regeneration and in the formation and function of

94 effect of Sema7a supplementation on corneal nerve regeneration and inflammation.

95 ively in the cornea, and potently stimulates nerve regeneration and inflammatory cell influx.

96 Therefore, this immune semaphorin links nerve regeneration and inflammatory processes in the cor

97 this signaling mechanism upregulates corneal nerve regeneration and may be targeted in neurotrophic k

98 ie the functional alterations observed after nerve regeneration and may explain how nerve damage lead

99 ddition, there appear to be abnormalities of nerve regeneration and of sodium and calcium channels.

100 d corneas, diabetes markedly delayed sensory nerve regeneration and reduced the number of infiltratin

101 However, nerve regeneration and remyelination are both perturbed,

102 The maturation of MPC activates nerve regeneration and restores functional motor units.

103 xpression significantly disrupted peripheral nerve regeneration and subsequent neuromuscular junction

104 a significant increase in corneal epithelial nerve regeneration and substance P-positive nerve densit

105 for Apobec proteins during retina and optic nerve regeneration and suggest DNA demethylation may und

106 6a and KLF7a as important mediators of optic nerve regeneration and suggest that not all induced gene

107 eal such ulcers may include the promotion of nerve regeneration and survival of epithelial progenitor

108 plays function-conducive roles in peripheral nerve regeneration and synaptic plasticity.

109 , the identification of signals that control nerve regeneration and the cellular events they induce i

110 ed sciatic nerve greatly enhance the rate of nerve regeneration and the restoration of nerve function

111 cal treatment with PEDF+DHA promotes corneal nerve regeneration and wound healing in diabetic mice an

112 ellularized designer conduits for peripheral nerve regeneration, and could lead to the development of

113 tivity, is anti-angiogenic, promotes corneal nerve regeneration, and induces cell survival.

114 ch artemin could influence bladder function, nerve regeneration, and pain, and provide a strong micro

115 e medicine, including optogenetics and optic nerve regeneration; and diagnostics (minimally invasive

116 Olfactory nerve regeneration appears to be a useful in vivo model

117 Focal nerve regeneration at the sites of radiofrequency ablati

118 t induction of Socs3 and Sfpq inhibits optic nerve regeneration but does not block it.

119 d (DHA), has been shown to stimulate corneal nerve regeneration, but the mechanisms involved are uncl

120 ssary for transgene reinduction during optic nerve regeneration, but were not as important for transg

121 iated NPD1 synthesis is suggested to precede nerve regeneration by demonstration of its accumulation

122 t study sheds light on the mechanism of pulp nerve regeneration by identifying C5L2 as a negative reg

123 We conclude that ATF3 contributes to nerve regeneration by increasing the intrinsic growth st

124 ng treatments to alleviate the inhibition of nerve regeneration by repulsive factors.

125 te form of beta(1, 3)-glucan] promotes optic nerve regeneration comparable to zymosan in WT mice, but

126 However, despite significant nerve regeneration, corneal nerve density does not recov

127 Even a modest improvement in nerve regeneration could have significant clinical impli

128 s to halt or reverse nerve damage or promote nerve regeneration, early diagnosis of diabetic polyneur

129 the extrinsic cues available in the natural nerve regeneration environment.

130 systemic MSC treatment resulted in improved nerve regeneration following allogeneic hindlimb transpl

131 the hypothesis that ES would enhance sensory nerve regeneration following digital nerve transection c

132 of axons, a vital requirement for successful nerve regeneration following injury.

133 crophages have been implicated in peripheral nerve regeneration for some time, supposedly through the

134 Peripheral nerve regeneration has been studied extensively, with pa

135 nges in gene expression that accompany optic nerve regeneration has led to the identification of prot

136 However, the potential for PLL nerve regeneration has not been tested yet beyond the ea

137 ap, but the role of these molecules in optic nerve regeneration has not been well studied.

138 n with docosahexaenoic acid (DHA) on corneal nerve regeneration in a mouse model of diabetes with or

139 GC development, promotes long-distance optic nerve regeneration in adult rats of both sexes.

140 on (ES) has been shown to enhance peripheral nerve regeneration in animal models following axotomy an

141 A thorough understanding of nerve regeneration in Caenorhabditis elegans requires pe

142 best suited to study functional outcome and nerve regeneration in CTA.

143 only identified mechanisms underlying optic nerve regeneration in fish but also suggest new molecula

144 st new molecular targets for enhancing optic nerve regeneration in mammals.

145 s an efficient strategy to measure and study nerve regeneration in man.

146 logical blockade of RAGE impaired peripheral nerve regeneration in mice subjected to RAGE blockade an

147 ent complement C5a receptor (C5aR) in dental nerve regeneration in regards to local secretion of nerv

148 To assess the potential role of nerve regeneration in restoring urinary tract function,

149 estosterone propionate (TP), augments facial nerve regeneration in the adult hamster.

150 During nerve regeneration in the adult, the expression of these

151 We first confirmed that PEDF + DHA increased nerve regeneration in the mouse cornea.

152 ty could provide new strategies to stimulate nerve regeneration in the PNS, fine control of mTOR acti

153 Hence, eNG and rNG can enhance nerve regeneration in the same way as isografts.

154 aims to investigate the role of C5L2 in pulp nerve regeneration in the secretion of BDNF by pulp fibr

155 n normal corneas, exogenous CNTF accelerated nerve regeneration in the wounded corneas of diabetic mi

156 Teleost fish show a remarkable capability of nerve regeneration in their CNS, while injuries to axon

157 y to be an important regulator of peripheral nerve regeneration in vitro and in vivo, but as determin

158 Here, we show that optic nerve regeneration in vivo correlates with Schwann cell-

159 Ralpha1 is dispensable for organogenesis and nerve regeneration in vivo, indicating that trans-signal

160 by MAG and that spermidine can promote optic nerve regeneration in vivo.

161 using thy1-YFP mice as a model for studying nerve regeneration in vivo.

162 tion of neural circuits in vitro, as well as nerve regeneration in vivo.

163 ection of nerve growth in vitro, and promote nerve regeneration in vivo.

164 rons, where it may play an important role in nerve regeneration in vivo.

165 -GFP) stimulated axonal sprouting and facial nerve regeneration in vivo.

166 ort that Jak/Stat signaling stimulates optic nerve regeneration in zebrafish.

167 complete and research to enhance peripheral nerve regeneration is clinically important.

168 Peripheral nerve regeneration is dependent on the ability of regene

169 Previous studies indicate that nerve regeneration is hampered by activation of RhoA/ROC

170 Together, these results show that olfactory nerve regeneration is significantly slower in KO mice as

171 matrix interactions, with important roles in nerve regeneration, metastasis, inflammation, and fibros

172 In vivo, VEGF-B is required for normal nerve regeneration: mice lacking VEGF-B showed impaired

173 evelop and validate a standardized cutaneous nerve regeneration model and to define the rate of epide

174 ts the hypothesis that augmented sympathetic nerve regeneration (nerve sprouting) increases the proba

175 ent of different gene regulatory networks in nerve regeneration, neuronal cell death and neuropathy i

176 During Xenopus laevis optic nerve regeneration, NF subunit composition undergoes pro

177 he mechanisms responsible for the more rapid nerve regeneration observed after a previous (conditioni

178 Peripheral nerve regeneration often remains incomplete, due to an i

179 ver time with genes previously implicated in nerve regeneration or plasticity, we found a gene cluste

180 the role of the PA system during peripheral nerve regeneration, PA-dependent activity as well as rec

181 on of peripheral nerve as well as regulating nerve regeneration pathways in vivo.

182 hamber model was used to evaluate peripheral nerve regeneration (PNR) in streptozocin (STZ)-induced d

183 Axonal outgrowth during peripheral nerve regeneration relies on the ability of growth cones

184 ecruitment of functional CH fibers following nerve regeneration requires enhanced TRPV1 levels.

185 VEGF-B treatment increased nerve regeneration, sensation recovery, and trophic func

186 Nerve regeneration studies at the neuromuscular junction

187 However, nerve regeneration studies require long-term recovery of

188 rm hospital" allows us to perform the entire nerve regeneration studies, including on-chip axotomy, p

189 ans has opened new opportunities for in vivo nerve regeneration studies.

190 that exhibit an intrinsic capacity for optic nerve regeneration, such as zebrafish, remains unknown.

191 GCs) individually promoted significant optic nerve regeneration, such regrowth tapered off around 2 w

192 hindpaw skin and L2/L3 DRGs after saphenous nerve regeneration suggested that inhibition of the pote

193 l role in physiological processes, including nerve regeneration, synaptic function, and behavior.

194 Although compensation for some nerve regeneration takes place, the alterations in the s

195 Limitations in current nerve regeneration techniques have stimulated the develo

196 that a favorable environment is critical for nerve regeneration, the complex cellular interactions be

197 After two distinct patterns of nerve regeneration, the subbasal nerves recovered to 65%

198 CSPGs inhibit nerve regeneration through receptor protein tyrosine pho

199 his precise surgical technique should enable nerve regeneration to be studied in vivo in its most evo

200 ed GSK3 activity showed markedly accelerated nerve regeneration upon injury.

201 e estrogen receptor modulator, on peripheral nerve regeneration, using a model of sciatic nerve crush

202 se findings suggest that Fn14 contributes to nerve regeneration via a Rac1 GTPase-dependent mechanism

203 ck-in mice reportedly accelerates peripheral nerve regeneration via increased MAP1B phosphorylation a

204 Post-wound nerve regeneration was also delayed in the DC-depleted c

205 Similarly, optic nerve regeneration was completely unaffected, although r

206 Nerve regeneration was enhanced by treadmill training po

207 The rate of peripheral nerve regeneration was enhanced in the transgenic mice t

208 tional importance of OPN and CLU, peripheral nerve regeneration was examined in OPN and CLU(-/-) mice

209 ontribution of acute inflammation to sensory nerve regeneration was investigated in the murine cornea

210 Focal terminal nerve regeneration was observed only at the sites of abl

211 tudy shows that lens injury-stimulated optic nerve regeneration was significantly compromised in thes

212 well established model of postcrush sciatic nerve regeneration was used to test the hypothesis that

213 To identify genes involved in successful nerve regeneration, we analyzed gene expression in zebra

214 ndly, using our techniques, reduced rates of nerve regeneration were found in people with diabetes wi

215 onal mechanism linking C5aR and C5L2 in pulp nerve regeneration, which may be useful in future dentin

216 rimotor functions are restored by peripheral nerve regeneration with greater success following injuri

217 T/A) in GSK3(S/A) RGCs further boosted optic nerve regeneration, with axons reaching the optic chiasm

218 ect, which is a model for composite bone and nerve regeneration, with both models avoiding involvemen