ライフサイエンスコーパス: nervous

1 Chronically elevated sympathetic nervous activity underlies many cardiovascular diseases.

2 nd metabolic changes are orchestrated by the nervous and endocrine systems.

3 creas and reveals a conversation between the nervous and immune systems using distinct receptors.

4 These same interactions facilitate nervous and metabolic system's influence on cardiovascul

5 There is nervous control of the heart by ATP as a cotransmitter i

6 d with health effects on the cardiovascular, nervous, gastrointestinal, metabolic, respiratory, and r

7 se, on neuronal transmission, and on central nervous network dysfunction are poorly understood.

8 of Salmonella to disseminate to the central nervous system (CNS) after oral infection in C57BL/6J mi

9 ry environment is induced within the central nervous system (CNS) after WNV infection, leading to ent

10 e mechanisms by which WNV enters the central nervous system (CNS) and host-factors that are involved

11 The central nervous system (CNS) and its meningeal coverings accommo

12 nce of parallel degeneration of both central nervous system (CNS) and peripheral nervous system (PNS)

13 Infections of the central nervous system (CNS) are often acute, with significant m

14 , we sought to determine whether the central nervous system (CNS) can be infected by KSHV in HIV-posi

15 Tumors residing in the central nervous system (CNS) compromise the blood-brain barrier

16 ene expression that occur across the central nervous system (CNS) during neurological diseases do not

17 nonchordates, amphioxus develops its central nervous system (CNS) from a neural plate that is homolog

18 eous, static magnetic field (SMF) on Central Nervous System (CNS) glial cells are less investigated.

19 ssue-resident macrophages within the central nervous system (CNS) have essential roles in neural deve

20 anding of immune surveillance of the central nervous system (CNS) have repeatedly provoked dismissal

21 Microglia play essential roles in central nervous system (CNS) homeostasis and influence diverse a

22 Central nervous system (CNS) infection and neurological involvem

23 ue to inflammation are a hallmark of central nervous system (CNS) infections with neurotropic pathoge

24 valent health issue that can lead to central nervous system (CNS) inflammation with long-term behavio

25 elected cohort with mainly relapsing central nervous system (CNS) inflammatory diseases.

26 tection devices in reducing ischemic central nervous system (CNS) injury during SAVR.

27 r neuroinflammatory responses during central nervous system (CNS) invasion by trypanosomes and are as

28 chain reaction (PCR) is a marker of central nervous system (CNS) involvement in congenital hCMV infe

29 acute lymphoblastic leukemia (ALL), central nervous system (CNS) involvement is a major clinical con

30 Viral infection of the central nervous system (CNS) is complicated by the mostly irrepl

31 ificantly associated with ocular and central nervous system (CNS) lesions and showed the strongest as

32 Primary central nervous system (CNS) lymphoma (PCNSL) and primary testic

33 gene, Sex-lethal (Sxl), functions in central nervous system (CNS) neurons as part of a relay that spe

34 gnosis is difficult with concomitant central nervous system (CNS) pathology.

35 induced characteristics of the adult central nervous system (CNS) pose barriers to axonal regeneratio

36 Central nervous system (CNS) relapses are an uncommon yet devast

37 d with the development of a manifest central nervous system (CNS) synucleinopathy (odds ratio = 7.1).

38 croglial cells are phagocytes in the central nervous system (CNS) that become activated in pathologic

39 signal to the motor circuits of the central nervous system (CNS) through a series of pathways that i

40 Survivors of central nervous system (CNS) tumors (SHR=4.6, 95% confidence int

41 In the adult mammalian central nervous system (CNS), axonal damage often triggers neuro

42 ctively affects motor neurons in the central nervous system (CNS), causing the adult-onset degenerati

43 e-matter tracts throughout the human central nervous system (CNS), including loss of all commissural

44 s on the input and plasticity of the central nervous system (CNS), which may explain the absence of a

45 The discovery that central nervous system (CNS)-targeted autoreactive T cells requi

46 Notably, the first new central nervous system (CNS)-targeted oligonucleotide-based drug

47 ory cell recruitment at the diseased central nervous system (CNS).

48 ly 30% of the cells in the mammalian central nervous system (CNS).

49 defined demyelinating disease of the central nervous system (CNS).

50 major obstacle for tissue repair in central nervous system (CNS).

51 ally assumed to be a function of the central nervous system (CNS).

52 sential protection mechanisms in the central nervous system (CNS).

53 e disease that targets myelin in the central nervous system (CNS).

54 utes to the neuroinflammation in the central nervous system (CNS).

55 or hyperpolarizing inhibition in the central nervous system (CNS).

56 ntrol autoimmune inflammation in the central nervous system (CNS).

57 including those associated with the central nervous system (CNS).

58 l stem and progenitor cells from the enteric nervous system (ENS) might serve as a source of cells fo

59 The enteric nervous system (ENS) of the gastrointestinal tract contr

60 The enteric nervous system (ENS) regulates numerous gastrointestinal

61 1 envelope glycoprotein 120 in their central nervous system (HIVgp120tg) mount a transient IFNbeta re

62 ve interactions direct cells to form central nervous system (neural plate) or sensory placodes.

63 -term viability of neurons in the peripheral nervous system (PNS) and retina.

64 Injury to the peripheral nervous system (PNS) causes a dramatic shift in SC molec

65 central nervous system (CNS) and peripheral nervous system (PNS) in PD.

66 patients presenting with pain or peripheral nervous system (PNS) manifestations, 39% were LGI1-IgG s

67 y and chemosensory neurons of the peripheral nervous system (PNS) must signal to the motor circuits o

68 th sensory neuron clusters of the peripheral nervous system (PNS), and blood cells (hemocytes) requir

69 In the peripheral nervous system (PNS), developmental axon pruning relies

70 Here we show that the peripheral sympathetic nervous system (PSNS) is very underdeveloped in def-defi

71 e energy balance, which augments sympathetic nervous system (SNS) activation in response to metabolic

72 hat PTSD patients have augmented sympathetic nervous system (SNS) and haemodynamic reactivity during

73 PTSD patients have an overactive sympathetic nervous system (SNS) that could contribute to cardiovasc

74 Optogenetic activation of the sympathetic nervous system (SNS) upregulates NE uptake by SAMs and s

75 dipocytes, immune cells, and the sympathetic nervous system (SNS), wherein CB1 plays a key regulatory

76 s, presence of microcephaly or other central nervous system abnormalities, and timing of infection in

77 myelin development proceeds independently of nervous system activity, increasing evidence supports a

78 appropriate function can be restored to the nervous system after the critical period.

79 bies virus (PRV), that infect the peripheral nervous system and have to travel long distances along a

80 ation between spatially distant areas of the nervous system and in controlling motor circuits.

81 elationship to activation of the sympathetic nervous system and inflammation in 59 patients with cirr

82 ld help reveal fundamental properties of the nervous system and neurological diseases.

83 WHO classification of tumours of the central nervous system and on scientific developments since the

84 CL than in DLBCL located outside the central nervous system and ophthalmic regions.

85 nfluence the development and function of the nervous system and several complex host behaviors.

86 l function are compromised in the Drosophila nervous system and SRS patient cells.

87 d neurohormonal signaling of the sympathetic nervous system and the downstream ET system, respectivel

88 focuses on the etiology of DNA damage in the nervous system and the genome stability pathways that pr

89 from the extracellular fluid in the central nervous system and thus presents an essential obstacle t

90 f progenitor cells in the developing enteric nervous system are controlled by molecules such as the s

91 Many networks throughout the nervous system are organized into topographic maps, wher

92 Ultrasonography of the central nervous system can reveal inflammatory changes and devel

93 d leukemia, soft-tissue sarcoma, and central nervous system cancer.

94 h incidence of severe defects in the central nervous system caused by human cytomegalovirus (HCMV) co

95 bundant and evolutionarily conserved central nervous system cell type.

96 eous neurotransmission have been observed in nervous system circuits as long as methods have existed

97 s for a number of cardiovascular and central nervous system conditions, but the current drugs for the

98 RATIONALE: Sympathetic nervous system control of inflammation plays a central r

99 hways between gut microbiota and the central nervous system could include autonomic, neuroendocrine,

100 f the inflammasome in peripheral and central nervous system cytokine/chemokine inflammatory responses

101 econdary to central and, perhaps, peripheral nervous system damage.

102 (SHANK3, CDH10, CSMD1) or genes involved in nervous system development (NYAP2, ST6GAL2, GRM6).

103 7-RGS complexes regulate critical aspects of nervous system development and function.

104 d in neuron-glia interactions during central nervous system development and in hair follicle polarity

105 y is encoded and robustly established during nervous system development.

106 arrhythmia in females when acute sympathetic nervous system discharge was applied in the settings of

107 mia risk in the setting of acute sympathetic nervous system discharge.

108 vestigation included cancer (n = 31; 23.1%), nervous system diseases (n = 26; 19.4%), and injury and

109 ors between those three inflammatory central nervous system diseases in adults and children to suppor

110 ected with human metabolic diseases, central nervous system diseases, and neoplasms.

111 ial actions may advance our understanding of nervous system disorders and suggest strategies for the

112 hat encompassed the development of autonomic nervous system dysfunction and hypertension.

113 licing of C-Src in the developing vertebrate nervous system evolved to regulate neurogenesis.SIGNIFIC

114 uropeptide hormone oxytocin is a key central nervous system factor in the regulation of food intake a

115 e abnormalities were correlated with central nervous system findings, microcephaly, and the timing of

116 ing axon regeneration to occur in the mature nervous system following axonal injury.

117 imulation to targeted regions of the central nervous system for extended periods.

118 also correlate initial abnormalities of the nervous system found on imaging with postnatal clinical

119 put during locomotion.SIGNIFICANCE STATEMENT Nervous system function depends on the specific excitabi

120 fied behaviors, leaving open questions about nervous system function in the context of natural tasks.

121 of Munc13 autoinhibition profoundly impacts nervous system function in vivo.

122 Nervous system function relies on precise synaptic conne

123 oordinated electrical activity that underlie nervous system function.

124 molecule NCAM, play important roles in many nervous system functions during development and in adult

125 f GPR17 per se as an orchestrator of central nervous system functions, they challenge the utility of

126 nal malaise suggests exercise alters central nervous system functions.

127 The nervous system has limited capability to regenerate, so

128 e of insulin-responsive GLUT4 in the central nervous system has not been well characterized.

129 however, post-developmental functions in the nervous system have not been elucidated.

130 have been described in patients with central nervous system hypomyelination.

131 ide a paradigm for understanding the enteric nervous system in health and disease.

132 By showing involvement of the peripheral nervous system in MS, this proof-of-concept study may of

133 Central nervous system infection of neonatal and adult rats with

134 Patients with central nervous system injuries, injury requiring medical care i

135 ultrasound on memory impairment and central nervous system injury in a rat model of vascular dementi

136 ence progressive lung disease or cardiac and nervous system involvement (complicated sarcoidosis).

137 64; 95% CI, 1.19-2.27; P = .003), peripheral nervous system involvement (HR, 6.75; 95% CI, 2.31-19.7;

138 RATIONALE: The sympathetic nervous system is a major mediator of heart function.

139 The nervous system is believed to be a network of neurons in

140 The nervous system is emerging as a regulator of malignancy.

141 wann cell (SC) myelination in the peripheral nervous system is essential for motor function, and unco

142 nd distribution of such receptors within the nervous system is not well described.

143 Because the developing nervous system is particularly vulnerable to perturbatio

144 phosphorylation of specific residues in the nervous system is poorly understood.

145 and in phrenic motor neurons of the central nervous system led us to address the individual contribu

146 odel, in high-risk cluster the prevalence of nervous system malformation decreased by approximately 2

147 ith a focus on preventing congenital central nervous system malformations.

148 ifications (PTMs) reportedly tied to central nervous system maturation, myelin stability, and the pat

149 Synaptic refinement is a critical step in nervous system maturation, requiring a carefully timed r

150 C4A10 expression and function in the central nervous system may affect the regulation of systemic wat

151 The nervous system may include more than 100 residue-specifi

152 if they had symptomatic or untreated central nervous system metastases, had received anticancer thera

153 oligodendrocyte differentiation and central nervous system myelination.

154 ct critical populations of intrinsic cardiac nervous system neurons and alter cardiac repolarization.

155 These cytokines regulate central nervous system neurons to induce sleep.

156 and coregulate membrane potential in central nervous system neurons.

157 Enteric nervous system neuropathy causes a wide range of severe

158 haviors, despite having a physically limited nervous system of 302 neurons, is poorly understood.

159 mportant contribution to the ancient enteric nervous system of early jawless vertebrates, a role that

160 ent neurotoxins, which damages the brain and nervous system of human beings through fish consumption.

161 modification that is abundant in the central nervous system of mammals and which results from 5-methy

162 tivity levels when injected into the central nervous system of mice.

163 In the nervous system of vertebrates, its expression is enriche

164 ordinately in the same pathway in either the nervous system or spermatogenesis.

165 A core principle of nervous system organization is the diversification of ne

166 multiple sclerosis lesions and other central nervous system pathologies with prominent myelin injury,

167 ised DNA damage response (DDR) and prominent nervous system phenotypes.

168 myelination represents an important form of nervous system plasticity.

169 The nervous system plays a central role in regulating the st

170 ry neurons, demonstrating that the autonomic nervous system plays a substantial role in HSV pathogene

171 control of differentiation of mouse enteric nervous system progenitor cells by EDN3 requires regulat

172 over gastrointestinal functions, the central nervous system provides extrinsic neural inputs that mod

173 coordinate various functions in the central nervous system ranging from removing synaptic connection

174 Among these, signals from the sympathetic nervous system regulate HSC egress via its niche, but ho

175 The autonomic nervous system regulates cardiac electrical and mechanic

176 their functional role in organisms without a nervous system remains unclear.

177 show that primary cells from the rat central nervous system respond differently to photo-toxicity, in

178 Understanding how the peripheral nervous system responds to electro-mechanical stimulatio

179 Therefore, understanding how the nervous system shapes the immune response could have imp

180 ies suggest that, in addition to its role in nervous system signaling, AChE can also modulate non-neu

181 es of the development and evolution of human nervous system specializations.

182 at successive relays in the parasympathetic nervous system strongly resemble each other despite the

183 bility and additional central and peripheral nervous system symptoms but an absence of frontonasal or

184 Autonomic nervous system testing revealed no abnormalities in hear

185 d pathogenic modifications to the peripheral nervous system that elevate metastatic capacity.

186 structure and function and have potential as nervous system therapeutics as well.

187 ituitary-adrenal (HPA) axis, the sympathetic nervous system through the greater splanchnic nerve (GSN

188 The nervous system thus seems to partition the learning of o

189 This suggests the ability of the central nervous system to concurrently learn operating the BMI w

190 biogenic amine neurotransmitters through the nervous system to control and maintain pairing with fema

191 targeted different sites within the central nervous system to restore motor function following spina

192 The central and peripheral nervous system transcriptomes of the spider Cupiennius s

193 l age increased risk of leukemia and central nervous system tumors, older paternal age was not associ

194 d to the development of benign and malignant nervous system tumors.

195 Here we test if a mechanism in the central nervous system underlies thermal TCE.

196 oth correlative and causal evidence that the nervous system uses millisecond-scale variations in the

197 tissue (BAT) is regulated by the sympathetic nervous system via beta3-adrenergic receptors (beta3-AR)

198 ug delivery of macromolecules to the central nervous system via the intrathecal route.

199 quired demyelinating syndrome of the central nervous system will have a monophasic disease course, wi

200 2a is rapidly distributed within the central nervous system with a very favourable brain/blood ratio.

201 ommon, though 1 case did involve the central nervous system with few symptoms.

202 Editing is enriched in the nervous system, affecting molecules pertinent for excita

203 sor and a principal component of SOCE in the nervous system, altered the expression of 131 genes incl

204 amine neurotransmitters of the human central nervous system, and is involved in many behavioral respo

205 mation, medication use, tumor of the central nervous system, and no diagnosis.

206 atic vessels, including those in the central nervous system, and Schlemm's canal.

207 ssing biologically active C3a in the central nervous system, and their respective wild-type controls

208 In the central nervous system, apoE is produced primarily by astrocytes

209 size and the number of neurons in the human nervous system, as well as the cellular and molecular re

210 ustly expressed in the developing and mature nervous system, but its contributions to neural cell cir

211 OGT is enriched in the nervous system, but little is known about its importance

212 read of pathogenic proteins in the mammalian nervous system, but whether nonpathogenic ones spread is

213 cate that vpr-1 activity is important in the nervous system, germ line and intestine.

214 ophages instruct tissue repair in the liver, nervous system, heart, lung, skeletal muscle, and intest

215 asticity, but its role may extend beyond the nervous system, in tissues where local changes in transl

216 shes several cell types from the rat central nervous system, largely based on the relative proportion

217 small size of most terminals in the central nervous system, little is known about the regulation of

218 In the mammalian central nervous system, Lpd contributes to neuronal morphogenesi

219 including neurons and glia of the peripheral nervous system, melanocytes, and bone and cartilage of t

220 g predominantly to categories related to the nervous system, muscle development, and especially to me

221 In the mammalian nervous system, myelin provides electrical insulation fo

222 ic renal failure, involvement of the central nervous system, or death), and interventions (ie, renal

223 od pressure (BP) is regulated at the central nervous system, renal, and vascular levels, but the cell

224 inflammation is initiated by the sympathetic nervous system, resulting in the elevation of exosome-as

225 In many parts of the nervous system, signals pass across multiple synaptic re

226 and for treating diseases of the peripheral nervous system, such as chronic nausea, vomiting, pain,

227 ginated from different levels of the central nervous system, to the different compartments.

228 o neuronal classes in the C. elegans central nervous system, using VGLUT-pHluorin to monitor synaptic

229 bundantly expressed in the mammalian central nervous system, where it regulates intracellular calcium

230 about expression of UBE3A in the peripheral nervous system, where loss of maternal UBE3A might contr

231 on-activated Na(+) channels expressed in the nervous system, where they are involved in learning, fea

232 abnormal activity of the cardiac sympathetic nervous system, which are established risk factors in se

233 us has potential in the treatment of central nervous system-related pathologies, such as Alzheimer's

234 pressants, antipsychotics, and other central nervous system-targeted medications) are increasingly us

235 gularity of neuronal activity in the central nervous system.

236 Little is known about its role in the nervous system.

237 minating to colonize the purine-poor central nervous system.

238 the embryonic epidermis to give rise to the nervous system.

239 rain, only isoform-A has been studied in the nervous system.

240 sitive, and selective communication with the nervous system.

241 acity of this agent to penetrate the central nervous system.

242 nsity for metastasis to bone and the central nervous system.

243 tassium channels abundantly expressed in the nervous system.

244 d blood cells is a surrogate for AChE in the nervous system.

245 mutant Ras-induced tumors in the developing nervous system.

246 bition of acetylcholinesterase (AChE) in the nervous system.

247 (MS) is an autoimmune disease of the central nervous system.

248 the role of O-GlcNAc cycling in the central nervous system.

249 ys and, perhaps more generally, their entire nervous system.

250 are also essential for the plasticity of the nervous system.

251 mit axon regeneration in the adult mammalian nervous system.

252 ading to suboptimal treatment in the central nervous system.

253 s following early development of the central nervous system.

254 mission throughout the developing and mature nervous system.

255 rocessing and motor rhythm generation in the nervous system.

256 t the genetic ablation of Lpd to the central nervous system.

257 ate and have well-characterized roles in the nervous system.

258 n result in damage to the developing central nervous system.

259 phalitogenic effector T cells in the central nervous system.

260 etylcholine receptors present in the central nervous system.

261 le fetal and neonatal tissues, including the nervous system.

262 vere congenital malformations of the central nervous system.

263 ative and autoimmune diseases of the central nervous system.

264 tic information from the gut directly to the nervous system.

265 ffects of metabolic disorders on the central nervous system.

266 stating consequences for the function of the nervous system.

267 n of virally transduced cells in the central nervous system.

268 n changes in the developing Drosophila pupal nervous system.

269 ning spatial pattern preferences in a simple nervous system.

270 es essential roles in the functioning of the nervous system.

271 l trials in a wide range of disorders of the nervous system.

272 munication between the immune system and the nervous system.

273 t require microglial function in the central nervous system.

274 ory neurotransmission throughout the central nervous system.

275 receptor abundantly expressed in the central nervous system.

276 eukin-8 in the respiratory tract and central nervous system.

277 lammatory effects, as well as to protect the nervous system.

278 r organisms to information processing in the nervous system.

279 iple roles in the development of the central nervous system.

280 ation of hepatic functions via the autonomic nervous system.

281 ic composition and function in the mammalian nervous system.

282 kinase in preserving genome stability in the nervous system.

283 oligodendroglial protein in the rat central nervous system.

284 he intrinsic immune sentinels of the central nervous system.

285 xhibits high viral burden within the central nervous system.

286 itch-specific labeled line in the peripheral nervous system.

287 eptide present in the CNS and the peripheral nervous system.

288 rotonin interact at the level of the central nervous system.

289 ring comprehensive genome maintenance in the nervous system.

290 amage and BACE1 up-regulation in the central nervous system.

291 oskeleton both at the AIS and throughout the nervous system.SIGNIFICANCE STATEMENT Spectrin cytoskele

292 cal disorders of both the CNS and peripheral nervous systems (PNS), yet few studies have directly exa

293 ugh their presence in amyloid plaques in the nervous systems of affected individuals.

294 tions of the sympathetic and parasympathetic nervous systems, along with potential non-autonomic mech

295 ciently transduce the central and peripheral nervous systems, respectively.

296 nt and maintenance of central and peripheral nervous systems.

297 of interest in and research into cnidarians nervous systems.

298 ystems, including the immune, metabolic, and nervous systems.

299 are found in both the central and autonomic nervous systems.

300 ubiquitinated protein inclusions present in nervous tissue of most cases of both amyotrophic lateral