ライフサイエンスコーパス: neu gene

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1 he human epidermal growth factor receptor 2/ neu gene.

2 (1,2) There was no amplification of the HER2/neu gene.

3 ymine on the nontemplate strand of the HER-2/neu gene.

4 le helix in the coding sequence of the HER-2/neu gene.

5 In the present study HER-2/neu gene amplification and expression was determined in

6 mely reliable in detecting presence of HER-2/neu gene amplification and should have clinical utility.

7 s to determine whether the presence of HER-2/neu gene amplification and/or overexpression in benign b

8 cer patients (N = 900) were tested for HER-2/neu gene amplification by FISH in paraffin-embedded, for

9 tive and specific method for assessing HER-2/neu gene amplification in archival tissue and to test wh

10 Our results demonstrate that HER-2/neu gene amplification in the absence of adjuvant therap

11 Case patients who had HER-2/neu gene amplification in their malignant tumor were mor

12 Fourteen percent of patients had HER-2/neu gene amplification in tumors compared with levels in

13 blotting procedures, FISH analysis of HER-2/neu gene amplification showed a sensitivity of 98% and a

14 HER-2/neu gene amplification was assessed by differential PCR,

15 HER-2/neu gene amplification was determined by FISH in 140 arc

16 The accuracy of the FISH assays for HER-2/neu gene amplification was high, 97.4% for the Vysis Pat

17 a bright-field assay for assessment of HER-2/neu gene amplification was investigated.

18 IMH false-positive cases (no Her-2/neu gene amplification) occurred with both HercepTest (2

19 ight-field assay for the assessment of HER-2/neu gene amplification.

20 on by FISH to determine the utility of HER-2/neu gene amplification.

21 f UPSCs but was rarely correlated with Her-2/neu gene amplification.

22 d that 79% (38 of 48) of 3+ cases were Her-2/neu gene amplified, but only 17% (seven of 41) of 2+ cas

23 ains in the EGFR and human EGFR type 2 (Her2/neu) genes and analyzed the expression of EGFR, EGFR del

24 nhibit transcription elongation in the HER-2/neu gene, and show that covalent modification of the DNA

25 (IHC) assays and not amplified for the HER-2/neu gene by fluorescence in situ hybridization were stud

26 Despite their proximity, CRD-BP and HER-2/neu genes can be amplified independently.

27 The HER-2/neu gene codes for a membrane receptor protein that is h

28 In the native HER-2/neu gene, covalent attachment of the triplex-forming oli

29 ransgenic mice harboring an activated MMTV-c-neu gene did not result in tumor regression.

30 Amplification or overexpression of the HER-2/neu gene in breast cancers is associated with aggressive

31 hown to inhibit transcription from the HER-2/neu gene in vitro, whereas their use in vivo has been st

32 st cancers, we introduced the human c-erbB-2/neu gene into the very low p185-expressing MDA-MB435 hum

33 The HER2/ERBB2/NEU gene is also frequently overexpressed in breast canc

34 rom chromosome 17q11-12 containing the HER-2/Neu gene is amplified in about 25% of breast cancer.

35 The enzyme encoded by the neuS gene is membrane-associated and has been suggested

36 mplification and overexpression of the HER-2/neu gene occurs in 25-30% of human breast cancers.

37 A1 or functional overexpression of the HER-2/neu gene presumably contributes to the somatic phenotype

38 Antibody to the Her-2/neu gene product has been shown to inhibit the growth of

39 with a synthetic peptide from the rat HER-2/neu gene product, which represents an epitope for CTLs i

40 synthesis in cells overexpressing the HER-2/neu gene product.

41 Our results suggest that the neuS gene product of E. coli K92 catalyzes the synthesis

42 hybridization (FISH)-based analysis of HER-2/neu gene status were performed on formalin-fixed, paraff

43 The conditional expression of activated HER2/neu gene under its endogenous promoter in the mammary ep

44 The K92 neuS gene was used to transform the K1 strain of E. coli

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