ライフサイエンスコーパス: neural plate border

1 functional, direct targets of Prdm1a at the neural plate border.

2 ork that controls cell fate decisions at the neural plate border.

3 erm are specified in adjacent domains at the neural plate border.

4 l crest specifiers, foxd3 and tfap2a, at the neural plate border.

5 crest induction in neuralized tissues or the neural plate border.

6 ads to loss of NC precursor formation at the neural plate border.

7 the total number of progenitor cells at the neural plate border.

8 within a pre-placodal domain at the cranial neural plate border.

9 anisms regulating cell fate decisions at the neural plate border.

10 ent progenitors that arise at the vertebrate neural plate border.

11 ired for the generation of cell fates at the neural plate border.

12 plate, while it is strongly activated at the neural plate border, a region which is populated by cell

13 neural crest development takes place at the neural plate border and consists in the induction of Pax

14 k if cephalochordates deploy Id genes at the neural plate border and dorsal neural tube in a manner s

15 s and vertebrates, expression in the lateral neural plate border and dorsal neural tube is a vertebra

16 nts contain cells fated to contribute to the neural plate border and even to the anterior neural plat

17 animal hemisphere at blastula stages and the neural plate border and neural crest at neurula stages.

18 precursor survival, leading to reduction of neural plate border and neural crest specifier genes Msx

19 The neural plate border and RBs were induced at the transpla

20 Notch in the regulation of cell fate at the neural plate border and that Notch regulates the total n

21 DNMT3A is expressed in the neural plate border, and its knockdown causes ectopic So

22 tion of neural crest-specific factors at the neural plate border appears to be a vertebrate novelty.

23 inductive roles of FGF, Wnt, and BMP at the neural plate border are well established, but the signal

24 Arising from the neural plate border at the intersection of Wnt and Bmp s

25 tent precursor cells that are induced at the neural plate border by a series of complex signaling and

26 Neural crest cells are induced at the neural plate border by the combined action of transcript

27 ory state upstream of multiple, pre-existing neural plate border cell differentiation programs.

28 s an integral role in the development of the neural plate border cell fates, including neural crest c

29 chordates (cephalochordates and tunicates), neural plate border cells express conserved factors such

30 However, invertebrate neural plate border cells have not been shown to generat

31 ar tail neuron precursors derive from caudal neural plate border cells, delaminate and migrate along

32 in the absence of further signals develop as neural plate border derivatives and eventually express l

33 , suggesting a permissive role for prdm1a in neural plate border-derived cell fates.

34 signaling and suggest a later involvement in neural plate border development, likely due to widesprea

35 These cells arise at the neural plate border during a time in development when pr

36 Id3 is localized at the neural plate border during gastrulation and neurulation,

37 Neural crest arises at the neural plate border, expresses a core set of regulatory

38 evel of BMP4 signaling is required to induce neural plate border fates, we directly tested BMP4's abi

39 that the contribution of dlx3b and dlx4b to neural plate border formation is partially non-cell-auto

40 and NSD3 is necessary for expression of the neural plate border gene Msx1, as well as the key neural

41 evaluated the effects of knocking down known neural plate border genes and early neural crest specifi

42 xogenous BMP affects expression of amphioxus neural plate border genes as in vertebrates, suggesting

43 Furthermore, it physically interacts with neural plate border genes Pax7 and Msx1 in vivo to direc

44 f Xash-3A may suppress further expression of neural plate border genes within the prospective neural

45 results putatively place Elk3 downstream of neural plate border genes, but upstream of neural crest

46 In Xenopus, the neural plate border gives rise to at least three cell po

47 g feature of vertebrate embryos, form at the neural plate border in response to inductive signals fro

48 Neural crest precursor cells arise at the neural plate border in response to inductive signals, bu

49 complex network of genes is activated at the neural plate border in response to neural crest-inducing

50 otent population of cells that arises at the neural plate border in the vertebrate embryo.

51 stem cell-like progenitors that arise at the neural plate border in vertebrates and migrate extensive

52 stem cell-like progenitors that arise at the neural plate border in vertebrates, migrate extensively,

53 the earliest genes activated in response to neural plate border-inducing signals.

54 e that the control of Sox8 expression at the neural plate border is a key process in initiating neura

55 ith dynamic confocal imaging reveal that the neural plate border is considerably broader and extends

56 t acquisition of AmphiSoxE expression in the neural plate border led to NCC emergence while duplicati

57 ound the neural plate, overriding the normal neural plate border limit of the early neural crest terr

58 BMP antagonists can induce neural plate border markers in both ventral Xenopus epid

59 ble to promote the expression of a subset of neural plate border (NPB) makers without the presence of

60 NC cells arise during gastrulation at the neural plate border (NPB), which is later elevated as th

61 central nervous system, a domain called the neural plate border (NPB).

62 NC and placodes form at the neural plate border (NPB).

63 is of transcription factor expression in the neural plate border of chick embryos.

64 We propose that the neural plate borders of the chordate ancestor already pr

65 The 'neural plate border' of vertebrate embryos contains prec

66 ity evolves into two distinct domains at the neural plate border: one coinciding with the neural cres

67 est induction rather than general defects in neural plate border or dorso-ventral patterning.

68 xpression shows that early inducing signals, neural plate border patterning genes, and melanocyte dif

69 ovel properties upon the evolving vertebrate neural plate border, potentiating the evolution of defin

70 affecting cell death or proliferation at the neural plate border, prdm1a acts explicitly on cell fate

71 c-myc is localized at the neural plate border prior to the expression of early neu

72 ebrate-specific elaborations on an ancestral neural plate border program, through acquisition of migr

73 lamprey AP-2 appears to function early as a neural plate border rather than a neural crest specifier

74 The inductive signals at the neural plate border region are likely to involve a gradi

75 e of a preplacodal domain within the cranial neural plate border region.

76 es of transcription factors expressed at the neural plate border, Sox proteins have been shown to reg

77 rparts of these genes function downstream of neural plate border specification in the regulatory netw

78 lly upregulates genes expressed early in the neural plate border such as Xsna, Xslu, Pax-3 and XANF a

79 uggesting that conserved signals specify the neural plate border throughout chordates.

80 e neural crest migrates from its origin, the neural plate border, to form diverse derivatives.

81 are multipotent progenitors that form at the neural plate border, undergo epithelial-mesenchymal tran

82 To establish regulatory relationships at the neural plate border, we assess relative expression of 6

83 eural crest, with earliest expression at the neural plate border where neural crest is induced.

84 b transcription factors are expressed at the neural plate border where they play partially redundant

85 zic2b influences the induction of NC at the neural plate border, while both zic2a and zic2b regulate