ライフサイエンスコーパス: neurochemical

1 ould be useful for the in vivo monitoring of neurochemicals.

2 pH shifts but not to other commonly studied neurochemicals.

3 tection of other catecholamines and phenolic neurochemicals.

4 repinephrine deficiency, would improve brain neurochemical abnormalities and neuropathology.

5 Most neurochemical abnormalities in PRS rats are found in the

6 er, few studies have examined functional and neurochemical abnormalities specifically in the rostral

7 ain barrier in mo-br mice and corrects brain neurochemical abnormalities, (2) norepinephrine deficien

8 However, it is not yet clear whether the neurochemical acetylcholine (ACh) is necessary exclusive

9 ostimulants are devoid of the behavioral and neurochemical actions that define this class of drugs an

10 d suggest a new mechanism to disrupt cocaine neurochemical actions.

11 ndent pathway that modulates cocaine-induced neurochemical activity in the mesolimbic system.

12 d whether the mPOA modulates cocaine-induced neurochemical activity in the nucleus accumbens.

13 rm, WINCS Harmoni, which can measure in vivo neurochemical activity simultaneously across multiple an

14 expression of these methamphetamine-induced neurochemical adaptations.

15 diabetes, may be risk factors for prefrontal neurochemical alterations in BD.

16 ated relevant dopaminergic and glutamatergic neurochemical alterations in the cortex and the striatum

17 In addition, we probed for neurochemical alterations in the glutamatergic circuitry

18 ecreased with aging, and was associated with neurochemical alterations that included increased expres

19 ce before reviewing normative structural and neurochemical alterations that persist until early adult

20 nce of neuropathic pain and the accompanying neurochemical alterations without affecting normal pain

21 We supplement these data with anatomical and neurochemical analyses of nonrecorded L-ITCcs.

22 anning electrochemical microscopy (SECM) and neurochemical analysis inside single cells.

23 Behavior and neurochemical analysis suggests that the effects of alco

24 is critical to the use of microdialysis as a neurochemical analysis technique.

25 d (AA) and serotonin (5-HT), of relevance to neurochemical analysis, showed that the signals for DA w

26 ) mouse model that recapitulates many of the neurochemical, anatomic, pathologic and behavioral defec

27 asis is given to a comprehensive functional, neurochemical and anatomical classification of GABAergic

28 Given the neurochemical and anatomical heterogeneity of the BF, we

29 ce, which lack D-serine, exhibit many of the neurochemical and behavioral abnormalities observed in S

30 tegrin beta3 recapitulates the sex-dependent neurochemical and behavioral attributes of ASD.

31 the prophylactic effect of ketamine against neurochemical and behavioral changes that follow inescap

32 D2 receptor (D2R) in the striatum as well as neurochemical and behavioral changes to methamphetamine

33 -22-sensitive transporters might enhance the neurochemical and behavioral effects of SSRIs.

34 onergic attenuation of cocaine abuse-related neurochemical and behavioral effects.

35 ed that these KO mice exhibit a lithium-like neurochemical and behavioral phenotype, here we searched

36 Finally, a significant degree of neurochemical and behavioral variation in response to me

37 Both of these effects, neurochemical and behavioral, were most pronounced durin

38 discuss advances in our understanding of the neurochemical and cellular heterogeneity of LHA neurons

39 bserved between treatment-related changes in neurochemical and cognitive outcomes.

40 Understanding the underlying neurochemical and connectivity-based brain mechanisms of

41 ulate not only affective state, but also the neurochemical and downstream neurophysiological environm

42 Their neurochemical and electrical features have been classica

43 model of inflammation was used to assess the neurochemical and functional changes induced by inflamma

44 Our data suggest a new view into the neurochemical and functional properties of BAT-related P

45 tudies in non-human primates, where targeted neurochemical and genetic manipulations can be made, are

46 We also discuss some of the stress-induced neurochemical and molecular alterations in these brain r

47 Neurochemical and molecular biomarkers were measured wit

48 on is a chronic, relapsing disease caused by neurochemical and molecular changes in the brain.

49 wk around their birth and exhibit deficient neurochemical and morphological maturation, including re

50 s to environmental cues, personality traits, neurochemical and pharmacogenetic differences.

51 ogical changes in patients by brain imaging, neurochemical and pharmacological approaches.

52 eal-time simultaneous monitoring of multiple neurochemicals and direct-current electrocorticography (

53 gest alteration of developmentally important neurochemicals and lateral ventricle dilation may be mec

54 The behavioral, neurochemical, and anatomical biomarkers in the mouse mo

55 gical mechanisms using electrophysiological, neurochemical, and behavioral procedures.

56 This relationship was component, neurochemical, and brain region specific.

57 eatment normalized the electrophysiological, neurochemical, and cognitive deficits in SR(-/-) mice.

58 aft-derived neurons exhibited morphological, neurochemical, and electrophysiological characteristics

59 somers and employed a battery of behavioral, neurochemical, and electrophysiological procedures to as

60 ections, less is known about the anatomical, neurochemical, and functional basis of nociceptive colla

61 sion of UOx exacerbates these morphological, neurochemical, and functional lesions of the dopaminergi

62 These results demonstrate anatomical, neurochemical, and task specificity and suggest that vis

63 BLA by using a combination of anatomical and neurochemical approaches.

64 ligation (SNL) via electrophysiological and neurochemical approaches.

65 However, whether levels of these neurochemicals are abnormal in epileptic patients is unk

66 onal methods for monitoring nonelectroactive neurochemicals are limited by slow sampling rates.

67 been developed to investigate the neural and neurochemical bases of different types of cost/benefit d

68 reasingly well characterized, the underlying neurochemical bases of individual differences in reading

69 Here we present a neurochemical basis for a localized gain control mechani

70 of spasmodic dysphonia and may represent the neurochemical basis of basal ganglia alterations in this

71 mice can be used to model and to dissect the neurochemical basis of executive abnormalities.

72 highlight the state- and practice-dependent neurochemical basis of human brain dynamics.

73 These findings also shed light on the neurochemical basis of individual susceptibility to valu

74 reliably demonstrated at rest, although the neurochemical basis of these 'resting state networks' is

75 lities in CNS disorders and their underlying neurochemical basis.

76 One of the putative neurochemical biomarkers for depression in major depress

77 onships between Hg and Se concentrations and neurochemical biomarkers in different brain regions of b

78 st sensitive (eg, interpersonal dynamics and neurochemical change) and the individual variability in

79 us to compare the relationship between these neurochemical changes and the physiological and peripher

80 -phenylethylamine; in humans and mice, these neurochemical changes are accompanied by neurodevelopmen

81 ss of the 10 mug/g threshold associated with neurochemical changes in Chiroptera conspecifics (n = 26

82 Fe exposure caused significant differential, neurochemical changes in critical regions of the brain,

83 s do not take advantage of real-time in vivo neurochemical changes in dynamic brain processes such as

84 e with Parkinson's disease can show premotor neurochemical changes in the dopaminergic and non-dopami

85 Neurochemical changes in the expression of various prote

86 ts brain function by inducing structural and neurochemical changes in the hippocampus and related med

87 on and leads to multiple local molecular and neurochemical changes in the raphe nuclei that dysregula

88 These neurochemical changes in VGF-knockout mice were associat

89 t of most agents and the need to explain how neurochemical changes reverse the many different symptom

90 The neurochemical changes underlying human emotions and soci

91 cts of BAY on memory performance and related neurochemical changes were partially blocked by the PKG

92 The neurochemical characteristics and distributions of pepti

93 These neurochemical characteristics of DMN deactivation may pr

94 Furthermore, to investigate the neurochemical characteristics of the BRS-3-expressing ne

95 o and present here the first biochemical and neurochemical characterization of these mutant animals.

96 es anxiety and stress responses via distinct neurochemical circuits.

97 s with different sensitivities between major neurochemical classes (gamma-aminobutyric acid [GABA]/gl

98 gdalar pathway innervated preferentially the neurochemical classes of calbindin and calretinin neuron

99 We found that different neurochemical classes of enteric neuron differed in thei

100 multaneous labeling of pathways and distinct neurochemical classes of inhibitory neurons, followed by

101 ew PPE positive catecholaminergic neuron but neurochemical codes were largely unidentified.

102 nflammation by controlling ENS structure and neurochemical coding, along with intestinal neuromuscula

103 external environment can be used to overcome neurochemical communication deficits in this important b

104 These results establish modes of neurochemical communication from brain regions controlli

105 Similarities on the cellular and neurochemical composition of the amygdaloid subnuclei su

106 The neurochemical composition of this region is complex, con

107 how TBI changes the metabolism of essential neurochemical compounds, summarize how neuroimaging appr

108 electrophysiological characteristics lacking neurochemical confirmation.

109 This neurochemical connectivity database (ChemNetDB) is suppo

110 Understanding the rat neurochemical connectome is fundamental for exploring ne

111 investigations into a multiscale, multilayer neurochemical connectome of the rat brain.

112 have been used extensively to determine the neurochemical consequences of chronic ethanol exposure,

113 holaminergic neurons are activated and other neurochemical content is largely unknown hence whether s

114 al of the present study was to determine the neurochemical content, innervations, and distribution of

115 d negative affective states, wherein several neurochemicals converge and interact to coordinate diver

116 These results identify a neurochemical correlate for a laboratory drug-seeking pa

117 ing effects of neuropeptide Y (NPY), another neurochemical correlate of arousal, and potentiates NPY'

118 dopamine (DA) as an electrophysiological and neurochemical correlate of reinforcement learning.

119 revented dyskinesias simultaneously with its neurochemical correlates such as the surge of nigral GAB

120 ganglia-thalamo-cortical circuitry; however, neurochemical correlates underpinning these abnormalitie

121 Exercise attenuates methamphetamine-induced neurochemical damage in the rat brain, and a preliminary

122 ion results in aberrant neural networks with neurochemical deficiencies that persist after transplant

123 over other rewarding activities, and exhibit neurochemical deficits related to dopamine, which is inv

124 These behavioral and neurochemical differences may reflect blockade of the no

125 ychiatric disorders are likely due to subtle neurochemical differences, and it remains unknown whethe

126 and suggest a computational, anatomical, and neurochemical dissociation of value- and salience-based

127 sed in selective detection and estimation of neurochemical dopamine by electrochemical method.

128 novel in vitro approach for monitoring fast neurochemical dynamics in model cell systems using micro

129 ty of molecular fMRI for characterization of neurochemical dynamics.

130 irected behavior, providing insight into the neurochemical dysfunction that may underlie the inflexib

131 obsessive-compulsive disorder, may be due to neurochemical dysfunction within the circuitry that enab

132 o a collection of studies that have examined neurochemical (e.g., glutamatergic and gamma-aminobutyri

133 ly bears sampled had Hg levels exceeding the neurochemical effect level proposed for polar bears.

134 This neurochemical effect was thought to require inhibition o

135 ropeptides are in a position to modulate the neurochemical effects of METH and consequently striatal

136 ficits in motor function, and alterations in neurochemical effects of nicotine.

137 eks before a stressor, blunts behavioral and neurochemical effects of the stressor.

138 inhibitor scaffold for preventing the deadly neurochemical effects of the toxin.

139 nistration and did not account for treatment neurochemical effects.

140 opamine transmission, we performed anatomic, neurochemical, electrophysiologic, and behavioral invest

141 identify biological cascades involved in the neurochemical, electrophysiological, and behavioral effe

142 a complex interplay of genetic, epigenetic, neurochemical, endocrine, and inflammatory contributors,

143 that these neuroadaptations represent a key neurochemical event in compulsive drug use and relapse.

144 ings together physiological, behavioral, and neurochemical evidence to examine variability in the exc

145 treatment regimen, electrophysiological and neurochemical experiments were performed to assess possi

146 a better understanding of the anatomical and neurochemical features of this pathway.

147 ddition, WINCS Harmoni can provide real-time neurochemical feedback for closed-loop control of neuroc

148 A striking neurochemical form of compartmentalization has been foun

149 thologous genetic variation on behaviors and neurochemical functions related to the 5-HT system.

150 Historically, brain neurochemicals have been broadly classified as energetic

151 ined this issue with an appreciation for the neurochemical heterogeneity of these nuclei.

152 Neuropeptides are an important class of neurochemicals; however, measuring their concentration i

153 To delineate the neurochemical identities of valop cells and to test for

154 d the detailed morphology, connectivity, and neurochemical identity of neurons in these nuclei.

155 In this study, in chicks, we revise the neurochemical identity of the isthmic nuclei by using in

156 However, the neurochemical identity of the majority of these VLPO-pro

157 ocation, morphology, projection pattern, and neurochemical identity of these cells by means of neural

158 satiety with peptide YY3-36 can reverse this neurochemical imbalance and acutely restore sleep compos

159 the hypothesis that an excitatory/inhibitory neurochemical imbalance might underlie ASD.

160 of L-dopa and alleviating LID by normalising neurochemical imbalance within the basal ganglia.

161 This trafficking might contribute to neurochemical imbalances observed in neuronal circuits i

162 lthough the depletion of dopamine is the key neurochemical impairment in PD and anticholinergic medic

163 ex interactions within the multicellular and neurochemical in vivo milieu.

164 ws for the in vivo quantification of various neurochemicals in the CSTC circuit and other brain regio

165 The most diverse and versatile neurochemicals in the insect nervous system are found in

166 selective for detecting rapidly fluctuating neurochemicals in vivo; however, many challenges exist f

167 ectrometry revealed reliable detection of 14 neurochemicals, including dopamine and acetylcholine, at

168 he observed concentration of a number of key neurochemicals increased dramatically including glycine

169 NAc) in the ventral striatum integrates many neurochemical inputs including dopamine and serotonin pr

170 m several brain areas which provide multiple neurochemical inputs to the LC with changes in LC neuron

171 ip between purine recycling pathways and the neurochemical integrity of the dopaminergic phenotype.

172 e relationships improve our understanding of neurochemical interactions in prefrontostriatal circuits

173 ite levels may provide biomarkers for future neurochemical interventions by pharmacologic or other me

174 en employed as a method of drug delivery for neurochemical investigations.

175 d is often utilized for targeted delivery in neurochemical investigations.

176 an be compensated for by bath application of neurochemicals known to accelerate the breathing rhythm.

177 own whether naturally occurring variation in neurochemical levels associate with individual differenc

178 chemical feedback for closed-loop control of neurochemical levels via its synchronized stimulation an

179 fic BNST neuronal types and their associated neurochemical makeup.

180 Neurochemical markers of amyotrophic lateral sclerosis (

181 ce spectroscopy showed altered levels of two neurochemical markers of neuronal function, taurine and

182 There are few neurochemical markers that reliably identify retinal gan

183 This study utilizes several neurochemical markers that reveal an emerging LCIC modul

184 bly of cell populations typically defined by neurochemical markers, such as the well-described neurop

185 region with regard to both connectivity and neurochemical markers.

186 dules that stain for GAD-67 as well as other neurochemical markers.

187 The composite neurochemical measure, myo-inositol+glycine/creatine, wa

188 which these associations, involving a single neurochemical measure, reflect more general effects of d

189 To assess incentive learning, behavioral and neurochemical measurements were made during the acquisit

190 in the central nervous system (CNS) is a key neurochemical mechanism involved in social bonding, part

191 However, the neurochemical mechanism of the DMN's deactivation remain

192 ivity by social laughter may be an important neurochemical mechanism reinforcing and maintaining soci

193 release after social laughter may provide a neurochemical mechanism supporting long-term relationshi

194 The current study investigated the neurochemical mechanism underlying semantic processing i

195 The current study examined the neurochemical mechanisms and neuroanatomical changes und

196 findings provide novel insight into cortical neurochemical mechanisms contributing to increased impul

197 Potential biochemical and neurochemical mechanisms for this protective effect are

198 sody is subserved by the same anatomical and neurochemical mechanisms involved in the processing of r

199 Understanding the neurochemical mechanisms mediating the prosocial effects

200 he continuous performance task use different neurochemical mechanisms subserving motor response inhib

201 atal, prefrontal, and insular regions as key neurochemical mechanisms underlying individual differenc

202 However, the neurochemical mechanisms underlying the attentional prio

203 However, the neurochemical mechanisms underlying this presymptomatic

204 Neurochemical mediators, including adenosine, and nonsyn

205 g brain microstructure, gene expression, and neurochemical metabolism across regions of the amygdala,

206 NRA neurochemical microstimulation also generated vocalizati

207 Neurochemical microstimulation in different parts of the

208 o substantiate the link between the cortical neurochemical milieu, the tuning of cortical activity, a

209 Further, a neurochemical mimic of the light input pathway evoked la

210 ignaling and by enhanced responsiveness to a neurochemical mimic of the light input pathway to the SC

211 ol the behavioral, electrophysiological, and neurochemical modifications caused by chronic unpredicta

212 colliculus exhibits connectional as well as neurochemical modularity and may contain multiple segreg

213 Many neurochemicals modulate olfactory information in the cen

214 se relationships in older adults, suggesting neurochemical modulation of cognitive flexibility change

215 o and from central vestibular structures and neurochemical modulation via the locus coeruleus and rap

216 g partners' interpersonal connection through neurochemical modulation.

217 atially related to the distribution of these neurochemical modules.

218 Neurochemical monitoring for long timescales is necessar

219 is sampling is an essential tool for in vivo neurochemical monitoring.

220 However, the neurochemical nature of the ATL in the semantic processi

221 s examined neuronal activation using Fos and neurochemical/neuroreceptor profiles on brain areas invo

222 d (+)-naltrexone, did not specifically block neurochemical or behavioral abuse-related effects of coc

223 tectable cognitive or motor deficits, and no neurochemical or biochemical evidence of injury in the s

224 s to firstly, visualize and quantify the STN neurochemical organization based on neuronal markers inc

225 In desert locusts the neurochemical organization of the central complex has be

226 A putative neurochemical output signal of the SCN, prokineticin 2 (

227 nts on innate anxiety, conditioned fear, and neurochemical parameters in the limbic system.

228 elease after social laughter would provide a neurochemical pathway supporting long-term relationships

229 ivity by social laughter may be an important neurochemical pathway that supports the formation, reinf

230 icals, has the potential to modulate several neurochemical pathways implicated in depression.

231 Neurochemical pathways involved in pathological overeati

232 However, elaboration of the neurochemical pathways that govern aggression has proven

233 ts reveal an unusual phenomenon in which the neurochemical phenotype of dopaminergic neurons is not l

234 tlining the neuroanatomical distribution and neurochemical phenotype of MCHR1 neurons.

235 Nutrient status determines the neurochemical phenotype of vagal afferent neurons by reg

236 ) were Phox2b+, VGlut2+, TH-, and ChAT-, the neurochemical phenotype previously defined for chemosens

237 xamined for tracer distribution and neuronal neurochemical phenotype.

238 nd suggest that some enteric neurons exhibit neurochemical phenotypes during development that are dif

239 rculation little is known of the origins and neurochemical phenotypes of the parasympathetic innervat

240 vagal afferent neurons express two different neurochemical phenotypes that can inhibit or stimulate f

241 ketamine occurs, in part, by reversing these neurochemical/physiological disturbances.

242 ines in the pathophysiology of SCZ and major neurochemical postulates of the disorder, including the

243 er task performance and imply that GABAergic neurochemical processes are potentially crucial to the n

244 ole: overlearning in humans abruptly changes neurochemical processing, to hyperstabilize and protect

245 as changes in activation, connectivity, and neurochemical profile in their missing hand's cortical t

246 ation of TRPM8 sensory neurons that have the neurochemical profile of cold nociceptors.

247 The electrophysiological properties and neurochemical profile of CSNs revealed an increase of no

248 d its effect on cognition, Ass, tau, and the neurochemical profile of the hippocampus.

249 Their soma size, neurochemical profile, and peripheral and central target

250 mice had alterations in ENS architecture and neurochemical profile, intestinal dysmotility, abnormal

251 veness to noxious peripheral stimulation and neurochemical profile.

252 mmation generates a pain state with a unique neurochemical profile.

253 hemistry to determine their molecular and/or neurochemical profile.

254 uality spectra enabled the quantification of neurochemical profiles consisting of at least eight meta

255 We suggest that neurochemical profiles of GluCEST contrast across cortex

256 rsity of other cell populations with complex neurochemical profiles that include neuropeptides, recep

257 nd multi-site recordings in combination with neurochemical profiling, we observed a predominant inhib

258 Therefore, we investigated the neurochemical properties of GABAergic interneurons in th

259 dulate in real time electrophysiological and neurochemical properties of mesencephalic dopaminergic (

260 eir morphological, electrophysiological, and neurochemical properties.

261 d cells preserved cortical morphological and neurochemical properties.

262 Here we report an integrated neurochemical recording platform for monitoring dopamine

263 Many of the phenotypic, neurochemical regulations encountered in lumbar DRGs in

264 However, whether estradiol enhances the neurochemical response to cocaine by acting in the mPOA

265 BI patients with time-locked analysis of the neurochemical response to seizures and pseudoperiodic di

266 stress and corticosterone on behavioral and neurochemical responses of rats to a cocaine prime after

267 freely moving rats to interrogate principal neurochemical responses to AMPH in the striatum and rela

268 Elucidation of taurine's neurochemical roles and importance would be substantiall

269 levels via its synchronized stimulation and neurochemical sensing capabilities.

270 separate electrodes and animals to evaluate neurochemical signals in multiple subjects.

271 Our results identify a neurochemical signature underlying abnormal reward proce

272 nse profiles, morphological characteristics, neurochemical signatures and electrical features.

273 OCD, we examined effective connectivity and neurochemical signatures in the pregenual anterior cingu

274 DGFRalpha/beta levels, reduced levels of the neurochemical SP, a reduction in CGRP fibers and changes

275 These results show anatomical and neurochemical specificity and are replicated in an indep

276 ctivity of neurons and astrocytes with their neurochemical state.

277 s of the emotional voalizations generated by neurochemical stimulation in the PAG.

278 ic hotspots are brain sites where particular neurochemical stimulations causally amplify the hedonic

279 We report here a detailed neurochemical, structural and physiological characteriza

280 In psychotic patients, neurochemical studies have confirmed subcortical striata

281 Electrophysiological and neurochemical studies implicate cholinergic signaling in

282 Neurochemical studies in human aggression point to a mod

283 The neurochemical study of the inferior olive and other prec

284 ulator of neural excitability and one of the neurochemical substrates of sleep.

285 al processing via the release of circulating neurochemicals such as hormones or neuromodulators.

286 results demonstrate that the underlying 5-HT neurochemical system is influenced by this functional po

287 hed light on the causal relationship between neurochemical systems and human prosocial behavior and h

288 eversal learning test, suggesting that these neurochemical systems exert important modulatory influen

289 the MC4 receptor (MC4R), also interacts with neurochemical systems that regulate socioemotional behav

290 of several brain regions and engage multiple neurochemical systems, including neuropeptides.

291 and attentional bias provides evidence for a neurochemical target, which may aid smoking cessation in

292 forts have been made to identify alternative neurochemical targets for treatment development in SCZ.

293 Here, we used behavioral, molecular, and neurochemical techniques to characterize the effects of

294 Glutamine and glutamate, neurochemicals that shuttles between neurons and astrocy

295 e, non-invasive spectroscopic measurement of neurochemicals through the skull, as well as other biome

296 lysate concentration of small molecule amine neurochemicals to be monitored with 20 s temporal resolu

297 ngs redefine patch/matrix beyond traditional neurochemical topography and reveal new principles about

298 We investigated the neurochemical underpinnings of this process.

299 s show that MeHg exposure is associated with neurochemical variation in the cerebellum of beluga whal

300 a Langmuir isotherm, and detection of other neurochemicals was also characterized, including ascorbi