ライフサイエンスコーパス: neurofilament

1 ers - Arp2, tau and an alpha-internexin-like neurofilament.

2 in neurons resulted in a decreased amount of neurofilament.

3 E revealed a 3-fold reduction in optic nerve neurofilaments.

4 ms as well as other proteins associated with neurofilaments.

5 s associated with reduced phosphorylation of neurofilaments.

6 letal components, F-actin, microtubules, and neurofilaments.

7 did not affect the distance between adjacent neurofilaments.

8 mild injury to the myelin sheaths or axonal neurofilaments.

9 inear viscoelastic properties of networks of neurofilaments.

10 erity but not with the survival time, as did neurofilaments.

11 ion and bundling of perikaryal and dendritic neurofilaments.

12 determines axonal diameter in the absence of neurofilaments.

13 29/mm(2), SD = 44; P < 0.01), phosphorylated neurofilament (1/transmittance = 1.16; SD = 0.09 versus

14 SY5Y cells, both mRNA and protein levels of neurofilament 160 (NF160) were significantly reduced, st

15 >97% of DRG neurons immunoreactive (IR) for neurofilament 200 (N52) or calcitonin gene-related pepti

16 ing femurs for tyrosine hydroxylase (TH) and neurofilament 200 (NF-200).

17 receptor potential vanilloid type 1 (TRPV1), neurofilament 200 (NF200), or vesicular glutamate transp

18 elated peptide (CGRP; sensory nerve fibers), neurofilament 200 kd (NF200; sensory nerve fibers), grow

19 alcitonin gene-related peptide (CGRP(+)) and neurofilament 200 kDa (NF200(+)) sensory nerve fibers.

20 linated non-nociceptive fibers (positive for neurofilament 200).

21 ssumed a neuronal cell morphology expressing neurofilament 200.

22 Using neurofilament-200 immunohistochemistry, we also detected

23 -like receptor 5 (TLR5) is co-expressed with neurofilament-200 in large-diameter A-fiber neurons in t

24 marrow denervation, demonstrating a loss of neurofilament-200 staining.

25 major autonomic source of axons labeled with neurofilament-200, which is commonly used to identify my

26 (SP), neuronal nitric oxide synthase (nNOS), neurofilament 200kDa (NF200), transient receptor potenti

27 Furthermore, we found a similar extent of neurofilament accumulation at NMJs in both vulnerable an

28 re the onset of denervation, suggesting that neurofilament accumulation does not predict subsequent N

29 regation precedes the abnormal and excessive neurofilament accumulation in these diseases, which in t

30 While neurofilament accumulation suggests an impairment of neu

31 using was sufficient to explain the observed neurofilament accumulation.

32 urofilaments in PNS diseases associated with neurofilament accumulation.

33 Neurofilament accumulations were observed only in the my

34 Presynaptic defects include phosphorylated neurofilament accumulations, nerve terminal sprouting, a

35 pyramidal layers, and induces phosphorylated neurofilament aggregation.

36 onal cytoskeletal polymers, microtubules and neurofilaments, align longitudinally in axons and are in

37 not account for the observed distribution of neurofilaments along mouse optic nerve axons.

38 c nerves showed a reduction in the number of neurofilaments, an increase in the number of microtubule

39 to directly examine the relationship between neurofilament and interneurons.

40 iations were detected between phosphorylated neurofilament and myelin basic protein (r = 0.58, P < 0.

41 mentous proteins of the cytoskeleton such as neurofilaments and alpha-internexin.

42 erity of glaucoma by staining the retina for neurofilaments and counting the neurons of the retinal g

43 The myelinated segments contained more neurofilaments and had a larger cross-sectional area tha

44 The model describes microtubules, neurofilaments and organelles as interacting particles i

45 t incorporates the longitudinal transport of neurofilaments and organelles through this domain by all

46 tion, a consequent increase in ubiquitinated neurofilaments and other proteins, and decrease the expr

47 ze that myosin Va is a short-range motor for neurofilaments and that it can function to enhance the e

48 We have shown previously that neurofilaments and vimentin filaments expressed in nonne

49 We show that neurofilaments and vimentin filaments lengthen by end-to

50 The degree of GFP expression by neurofilament(+) and peripherin(+) DRG neurons was simil

51 el expressed on all mitochondria) and axons (neurofilament), and ultrastructural imaging showed that

52 days after RD with antibodies to anti-GFAP, -neurofilament, and -rod opsin to examine cellular change

53 ession of the neuronal markers NeuN, nestin, neurofilament, and MAP-2 in medulloblastoma cells and in

54 markers such as nestin, doublecortin, GFAP, neurofilament, and vimentin.

55 lation, increased phosphorylation of tau and neurofilaments, and decreased microtubule-binding activi

56 d networks of interacting microtubules (MT), neurofilaments, and filamentous-actin in neurons where t

57 nce, myelin, cytochrome oxidase, ionic zinc, neurofilaments, and vesicular glutamate transporter 2 (V

58 ule-associated protein 2, synaptophysin, and neurofilament antigens.

59 ent of axonal swellings exhibiting compacted neurofilaments appeared to decrease, and was accompanied

60 Neurofilaments are elevated in the cerebrospinal fluid (

61 Neurofilaments are found in abundance in the cytoskeleto

62 Neurofilaments are intermediate cytoskeletal proteins th

63 Neurofilaments are intermediate filaments assembled from

64 The data suggest that neurofilaments are sensitive and specific blood markers

65 ial proposal that only a small proportion of neurofilaments are transported in axons and that the maj

66 rough naturally occurring gaps in the axonal neurofilament array of cultured superior cervical gangli

67 cell types with expression of neural markers neurofilament, beta-tubulin III, GFAP; or keratocyte-spe

68 tic axons and colocalizes with NFL on single neurofilaments by immunogold electron microscopy.

69 ucture arising from interactions between the neurofilaments' C-terminal sidearms.

70 and that specific neuronal markers (Brn3 and neurofilament) can partly distinguish between different

71 orming cylindrical axons (myelin sheaths and neurofilaments) can be locally invisible in phase images

72 Traumatic axonal injury (TAI) involves neurofilament compaction (NFC) and impaired axoplasmic t

73 Impaired axoplasmic transport (IAT) and neurofilament compaction (NFC), two common axonal pathol

74 ng studies with antibodies to phosphorylated neurofilaments confirmed the axonal location of full-len

75 icates side-arm-mediated attractions between neurofilaments consistent with an electrostatic model of

76 pose that myelinating cells can regulate the neurofilament content and morphology of axons locally by

77 ed NF-M C terminus extended farther from the neurofilament core independent of lysine-serine-proline

78 show that the force exerted by our base case neurofilament (D(NF)=10 nm, L(NF)=1.6 microm) is approxi

79 ury-myelin damage (positive sign) vs. axonal neurofilament damage (negative sign).

80 embranous organelles clustered centrally and neurofilaments displaced to the periphery.

81 focal swellings of retinal nerve fibres with neurofilament disruption.

82 tion, axons have a reduced-caliber, abnormal neurofilament distribution and an increase in mitochondr

83 eneration without cell body death, including neurofilament filled swellings, loss of calcium homeosta

84 In axons, parallel neurofilaments form a nematic liquid-crystal hydrogel wi

85 ltured rat cortical neurons with fluorescent neurofilament fusion proteins and then used photoconvers

86 The neurofilament gene NEFL harbored three SNPs associated w

87 ohistochemistry studies using synaptophysin, neurofilament H (NF-H) and amyloid-beta precursor protei

88 yed for the presence of serum phosphorylated neurofilament H (pNF-H).

89 and reduced expression of non-phosphorylated neurofilament-H which is associated with axon damage.

90 expression of axon-specific molecules (e.g. neurofilament-H) and reduced expression of non-phosphory

91 -associated actin-binding protein that, like neurofilament, has been linked to neuron shape.

92 ess-stiffening response of the soma, whereas neurofilaments have a predominant contribution in the vi

93 repeat motifs that are particularly found in neurofilament heavy (NF-H) and neurofilament medium (NF-

94 (Syt2) and complexin 1 (Cplx1)], structural [neurofilament heavy chain (Nefh)], and metabolic [neutra

95 ther the measurement of serum phosphorylated neurofilament heavy chain (pNF-H) titre is likely to be

96 We show that levels of phosphorylated neurofilament heavy chain (pNFH) in cerebrospinal fluid

97 Phosphorylated neurofilament heavy chain (pNfH) levels are elevated in

98 terokinase is membrane bound and cleaves the neurofilament heavy chain at positions 476 and 986.

99 tions were found between extracellular fluid neurofilament heavy chain levels and physiological param

100 Finally, extracellular fluid neurofilament heavy chain levels were of prognostic valu

101 n injury, microdialysate extracellular fluid neurofilament heavy chain levels were significantly high

102 ytic breakdown products, extracellular fluid neurofilament heavy chains NfH(476-986) and NfH(476-1026

103 A neurofilament heavy gene (NFH) promoter does not support

104 rat tyrosine hydroxylase (TH) promoter, to a neurofilament heavy gene (NFH) promoter.

105 The phosphorylated neurofilament heavy subunit (pNF-H), a major structural

106 carry distinct frameshift variants in NEFH (neurofilament heavy), leading to a loss of the terminati

107 phingomyelin phosphodiesterase 3 (SMPD3) and neurofilament, heavy polypeptide (NEFH), which we found

108 ament-light chain) and pNF-H (phosphorylated neurofilament-heavy chain) are normal before symptom ons

109 This suggests a dominant regulatory role for neurofilament-high sidearms in filament reorientation pl

110 neurofilament-low, neurofilament-medium and neurofilament-high.

111 nvolved in the degradation of peripherin and neurofilament IF proteins in neurons.

112 Myelin basic protein and neurofilament immunolabelling demonstrates that axons in

113 A group of morphologically distinct, 200-kD neurofilament-immunopositive myelinated afferent fibers,

114 was associated with significant increases in neurofilament immunoreactivity immediately below the SCI

115 ceiving GAS6 for 28 d had preserved SMI31(+) neurofilament immunoreactivity, significantly fewer SMI3

116 Neurofilament immunostaining of retinal whole-mounts con

117 Although phosphorylated neurofilament immunostaining revealed a few dystrophic n

118 The loss of neurofilament in juveniles exposed to darkness prior to

119 s-sectional distribution of microtubules and neurofilaments in axons.

120 lysis indicated an increase in ubiquitinated neurofilaments in midbrain of KO mice, whereas 20S prote

121 t the transport kinetics and distribution of neurofilaments in mouse optic nerve can all be explained

122 annealing." To test if this also occurs for neurofilaments in neurons, we transfected cultured rat c

123 vide a basis for its close relationship with neurofilaments in PNS diseases associated with neurofila

124 endent structure, peripherin is a subunit of neurofilaments in the adult PNS.

125 kinetic and morphometric data available for neurofilaments in the mouse visual system.

126 od1 but also mature neuronal markers such as neurofilament, indicating that Eya1 and Six1 function up

127 otic vesicles possessing sensory hair cells, neurofilament innervation in a thickened sensory epithel

128 Neurofilament-inspired biomimetic hydrogels should there

129 e for the deposition of axonally transported neurofilaments into a persistently stationary neurofilam

130 netics are not consistent with deposition of neurofilaments into a persistently stationary phase, and

131 eurons did not contain GABA, indicating that neurofilament is predominant in projection cells and not

132 we observed no alteration in neuron size or neurofilament labeling within the dLGN.

133 nd many of these have somatic phosphorylated neurofilament labeling.

134 Thus, blood and CSF neurofilament levels are linked to the symptomatic phase

135 CHIT1 and neurofilament levels were determined in cerebrospinal fl

136 Mutations in neurofilament light (NF-L) have been linked to Charcot-M

137 ing pathways, resulting in reduced levels of neurofilament light (NF-L) protein in distal axons and m

138 Cerebrospinal fluid (CSF) neurofilament light (NFL) concentration is a general mar

139 Plasma neurofilament light (NFL) has recently been proposed as

140 The neurofilament light (NFL) subunit is considered as an ob

141 , chemokine (C-C motif) ligand 2 (CCL2), and neurofilament light (NFL) were determined by commercial

142 sts with the neurofilament triplet proteins [neurofilament light (NFL), medium (NFM), and heavy (NFH)

143 Here, we assessed the utility of serum neurofilament light chain (NF-L) and tau protein in comp

144 We have used a recombinant neurofilament light chain (NF-L) protein for the ELISA d

145 a that reveals the ability of CSF and plasma neurofilament light chain (NF-L) to predict and track cl

146 The concentrations of neurofilament light chain (NF-L), myelin basic protein (

147 A clearer definition of the role of neurofilament light chain (NFL) as a biomarker in amyotr

148 Cerebrospinal fluid (CSF) neurofilament light chain (NfL) concentration is elevate

149 As a marker of axonal damage, neurofilament light chain (NfL) has been suggested a mar

150 Neurofilament light chain (NfL) represents a promising b

151 Cerebrospinal fluid (CSF) neurofilament light chain (NFL), a measure of axonal inj

152 ed tau (p-tau), beta-amyloid 1-42 (Abeta42), neurofilament light chain (NFL), alpha-synuclein (alpha-

153 t of HIV- subjects (n = 17) to CSF levels of neurofilament light chain (NFL), reflective of axonal da

154 ations between the QAlb and the CSF level of neurofilament light chain (NFL), the ratio of N-acetylas

155 1, as well as the neuronal damage biomarker, neurofilament light chain (NFL), were elevated compared

156 Elevated neurofilament light chain and its correlation with MRS-b

157 sphatase 2B catalytic subunit gamma isoform, neurofilament light chain and vesicular glutamate transp

158 Neurofilament light chain correlated with decreased N-ac

159 ssociated with the concentrations of tau and neurofilament light chain in the CSF, suggesting a neuro

160 Cerebrospinal fluid concentrations of neurofilament light chain protein, Abeta1-42, total tau,

161 In PD, high neurofilament light chain protein, low Abeta1-42, and hi

162 In PD, high neurofilament light chain protein, low Abeta1-42, and hi

163 showed that expression of disease-associated neurofilament light chain variants results in abnormal i

164 Neurofilament light chain was elevated in primary HIV in

165 We compared CSF concentrations of neurofilament light chain, t-tau, p-tau, amyloid precurs

166 and positively correlated with the levels of neurofilament light chain.

167 Neurofilament light chains (NfL) are unique to neuronal

168 on, Bacioglu, Maia, and colleagues show that neurofilament light concentrations in body fluids reflec

169 We identified a novel neurofilament light polypeptide (NEFL) nonsense mutation

170 oth disease (CMT) caused by mutations in the neurofilament light polypeptide gene (NEFL).

171 Multiple mutations in the neurofilament light polypeptide gene, NEFL, cause CMT2E.

172 We hypothesized that measurement of neurofilament light protein (NF-L), a protein found in l

173 Furthermore, neurofilament light protein concentrations correlated wi

174 We investigated whether neurofilament light protein NfL (also known as NF-L) in

175 Main Outcomes and Measures: Neurofilament light protein, total tau, glial fibrillary

176 and Relevance: Increased cerebrospinal fluid neurofilament light proteins and reduced amyloid beta we

177 Neurofilament light proteins were significantly increase

178 acid aggregate colocalizes and binds to the neurofilament light subunit protein that is associated w

179 ilar aggregation-inducing mechanism in NEFL (neurofilament light) and FUS (fused in sarcoma), in whic

180 Neurofilaments NF-L (neurofilament-light chain) and pNF-H (phosphorylated neu

181 ogels a narrow ionic strength range, whereas neurofilament-low hydrogels lack the isotropic gel phase

182 ediate filaments assembled from the subunits neurofilament-low, neurofilament-medium and neurofilamen

183 ic gel phase stability is sidearm-dependent: neurofilament-low-high hydrogels exhibit a wide ionic st

184 ometry, that with decreasing ionic strength, neurofilament-low-high, neurofilament-low-medium and neu

185 sing ionic strength, neurofilament-low-high, neurofilament-low-medium and neurofilament-low-medium-hi

186 drogels exhibit a wide ionic strength range, neurofilament-low-medium hydrogels a narrow ionic streng

187 ament-low-high, neurofilament-low-medium and neurofilament-low-medium-high hydrogels transition from

188 d in significant upregulation of Oct4, SSEA, Neurofilament M and GFAP with significant decreases in b

189 differentiated cells (Oct4, SSEA4), neurons (Neurofilament M), astrocytes (GFAP) or cell cycle phase,

190 h peak cell cycle exit at E11.5, followed by neurofilament-M neurons, calcitonin gene-related peptide

191 al thioflavin S correlated with decreases in neurofilament marker SMI32.

192 loads, changes at the substructural level of neurofilaments may precede microtubule rupture and degen

193 arly found in neurofilament heavy (NF-H) and neurofilament medium (NF-M) proteins.

194 ion, and is dependent upon the C terminus of neurofilament medium (NF-M).

195 well as an epitope within the axonal protein neurofilament medium (NF-M15-35) in H-2(b) mice.

196 te glycoprotein epitope 35-55 (MOG35-55) and neurofilament medium protein epitope 15-35 (NFM15-35).

197 hnRNP K-regulated cytoskeletal RNAs (tau and neurofilament medium), effects that were alleviated by e

198 sembled from the subunits neurofilament-low, neurofilament-medium and neurofilament-high.

199 We conclude that all of the neurofilaments move and that they do so with a single br

200 frequency of both anterograde and retrograde neurofilament movement.

201 Consequences of its loss include neurofilament network abnormalities, specifically accumu

202 t protein that is associated with pathologic neurofilament network disorganization and degeneration o

203 that the apparent existence of a stationary neurofilament network in mouse optic nerve is most likel

204 eurofilaments into a persistently stationary neurofilament network in optic nerve axons.

205 erin mutations has been shown to disrupt the neurofilament network in transfected SW13vim(-) cells.

206 , we show that the macroscopic properties of neurofilament networks are tuned by enzymatic regulation

207 We show that the elasticity of neurofilament networks is entropic in origin and is cons

208 nd Zn(2+) act as effective cross-linkers for neurofilament networks, controlling their solidlike elas

209 , CHX10(+) cells expressed neuronal markers [neurofilament, NeuN, and vesicular glutamate transporter

210 The gene expression of the structural neurofilament NF-H is found to be significantly downregu

211 Neurofilaments NF-L (neurofilament-light chain) and pNF-

212 at spinal MNs, but rarely non-MNs, exhibited neurofilament (NF) aggregation followed by neurite degen

213 In normal neurons, neurofilament (NF) proteins are phosphorylated in the ax

214 Neurofilament (NF) proteins detection in biological flui

215 Synaptic roles for neurofilament (NF) proteins have rarely been considered.

216 In mammals, there are three neurofilament (NF) subunits (NF-L, NF-M, and NF-H), but

217 ude low-, middle-, and high-molecular-weight neurofilament (NF) triplet proteins, designated NFL, NFM

218 uronal intermediate filaments comprising the neurofilament (NF) triplet proteins.

219 n family, which also includes peripherin and neurofilament (NF) triplet proteins.

220 iated from GAN iPSCs exhibit accumulation of neurofilament (NF-L) and peripherin (PRPH) protein and f

221 In mammals neurofilaments (NF) are formed by coassembly of three su

222 Neurofilaments (Nf) are major structural proteins that o

223 Brn3 transcription factor and the different neurofilaments (NF68, NF160, NF200) were able to discrim

224 additional study to investigate the value of neurofilament (NfH) and other biomarkers in predicting p

225 on as an extensively cross-linked network of neurofilaments (NFs) and other cytoskeletal polymers con

226 Neurofilaments (NFs) are important cytoskeletal filament

227 components, F-actin, microtubules (MTs), and neurofilaments (NFs), in the RNFL during the development

228 al accumulation of tangles of phosphorylated neurofilaments (NFs).

229 Transfected microtubules and neurofilaments of E17 rat neuronal axons are imaged befo

230 anism gradually segregates microtubules from neurofilaments on a time scale of hours, similar to that

231 aggregations of hyperphosphorylated Tau and neurofilaments, pathogenic hallmarks in neurodegenerativ

232 These data indicate that neurofilaments pause for more prolonged periods in the a

233 tissue interface was uniform and neurons and neurofilaments penetrated through the mesh by 3 mo posti

234 rs TrkA, TrkB, TrkC, and RET and the sensory neurofilament peripherin.

235 Neurofilament phosphorylation was also observed to incre

236 amyelin loops) and axonopathy (i.e., altered neurofilament phosphorylation, paranodal defects, and ch

237 and immunohistochemistry for phosphorylated neurofilaments (pNF) at 10 and 29 days after IOP increas

238 The number of neurofilament positive neurons expressing activated casp

239 The large majority of neurofilament-positive neurons did not contain GABA, ind

240 uces a pronounced overexpression of TRPV1 in neurofilament-positive pulmonary sensory neurons in nodo

241 beta-galactosidase under the control of the neurofilament promoter was detected in approximately 90%

242 With the SMI-32 antibody against neurofilament protein (NFP) as a marker of the motion-se

243 describe the expression of nonphosphorylated neurofilament protein (NPNFP) in the human vestibular br

244 We also noted that neurofilament protein SMI31 immunoreactivity was increas

245 0 days of darkness also enhanced the loss of neurofilament protein within deprived dLGN layers.

246 e, and also reversed the significant loss of neurofilament protein within originally deprived dLGN la

247 These data show that peripherin and the neurofilament proteins are functionally interdependent.

248 These include neurofilament proteins that constitute the stress-respon

249 entin(+) SW13 cells, and with peripherin and neurofilament proteins when transfected into N2a cells.

250 ed by significant reduction in the levels of neurofilament proteins, and alterations in axonal fiber

251 enous Nes-S co-assembles with peripherin and neurofilament proteins.

252 ding glutamate receptors, cell adhesion, and neurofilament proteins.

253 d precursor protein, and hyperphosphorylated neurofilament proteins.

254 al caliber through phosphorylation of axonal neurofilament proteins.

255 isorganized microtubules, microfilaments and neurofilaments, raising the hypothesis that hnRNP K post

256 eflecting myelin content) and phosphorylated neurofilament (reflecting axonal area)] using t-tests an

257 nemic iron deficiency on axonal diameter and neurofilament regulation in the auditory nerve.

258 somata with high alpha3 immunointensity were neurofilament-rich, suggesting they have A-fibres; we th

259 al analysis of renal arteries yielded a mean neurofilament score of healthy nerves that was significa

260 eurodegenerative disorders, microtubules and neurofilaments segregate apart from each other, with mic

261 This suggests that the microtubule-neurofilament segregation can be a consequence of the se

262 imary correlate of quantitative staining for neurofilaments (SMI31), markers of axonal integrity.

263 rease in the proportion of the time that the neurofilaments spent pausing and that this increase in p

264 Neurofilament staining revealed variable but prominent d

265 sions colocalize with the low-molecular-mass neurofilament subunit (NFL) or peripherin staining.

266 evealed plentiful mRNA for the low molecular neurofilament subunit and beta-tubulin, but very little

267 ween neurofilament subunits, indicating that neurofilament subunit content is not determined by neuro

268 a concentrations of the phophorylated axonal neurofilament subunit H, indicating that axonal integrit

269 The light neurofilament subunit is obligatory and can assemble wit

270 sed diameter of motor axons without altering neurofilament subunit stoichiometry.

271 tained a visible amount of labeling for each neurofilament subunit, and the bulk of these labeled cel

272 the first time in human lung tissue, 200-kD neurofilament subunit.

273 leus (dLGN) we examined whether labeling for neurofilament subunits and spectrin is linked to neuron

274 to neuron structure and function, and three neurofilament subunits different in their molecular mass

275 on of neuron sizes was not different between neurofilament subunits, indicating that neurofilament su

276 n which axons contain a single population of neurofilaments that all move stochastically in a rapid,

277 her proteins, and decrease the expression of neurofilaments that could be relevant to the mechanism o

278 nt of green fluorescent protein (GFP)-tagged neurofilaments through naturally occurring gaps in the a

279 urofilament transport in axons by delivering neurofilaments to their microtubule tracks, thereby redu

280 sis revealed that a decrease in abundance of neurofilament transcripts contributed to the reduction o

281 ament accumulation suggests an impairment of neurofilament transport along axons, the underlying mech

282 cape kinetics, we found that this slowing of neurofilament transport could be explained by an increas

283 it can function to enhance the efficiency of neurofilament transport in axons by delivering neurofila

284 -escape technique to compare the kinetics of neurofilament transport in contiguous myelinated and unm

285 imental artifact due to contamination of the neurofilament transport kinetics with cytosolic proteins

286 that this regulatory mechanism may influence neurofilament transport within axons.

287 explained fully by a "stop-and-go" model of neurofilament transport, in which axons contain a single

288 microtubules together, and in the absence of neurofilament transport, this mechanism gradually segreg

289 axons locally by modulating the kinetics of neurofilament transport.

290 is accumulation is a decrease in the rate of neurofilament transport.

291 a consequence of the selective impairment of neurofilament transport.

292 and this correlated with a local slowing of neurofilament transport.

293 neurodegenerative disease, coexists with the neurofilament triplet proteins [neurofilament light (NFL

294 orted a widely held view that peripherin and neurofilament triplets form separate filament systems.

295 bodies against choline-acetyltransferase and neurofilament was performed to differentiate motor and s

296 That reactivity for neurofilament was predominant in large cells led us to d

297 CSF neurofilaments were increased before symptom onset, whil

298 All three neurofilaments were primarily expressed in large M2 cell

299 By contrast, neurofilaments were significantly decreased in SN of KO

300 f space-filling cytoskeletal polymers called neurofilaments, which are cargoes of axonal transport.

301 lls begin to express the pan-neuronal marker neurofilament while still in the ectoderm.