ライフサイエンスコーパス: neuronal circuit

1 ermined by the position it occupies within a neuronal circuit.

2 of axon target choice in a nondeterministic neuronal circuit.

3 importance of specific connectivity within a neuronal circuit.

4 ner, thereby influencing the excitability of neuronal circuits.

5 nt and their importance for the formation of neuronal circuits.

6 mporal and cell type-selective modulation of neuronal circuits.

7 opment is required to refine the function of neuronal circuits.

8 essential for the formation and function of neuronal circuits.

9 ical roles in the development of hippocampal neuronal circuits.

10 part of both the circadian and sleep-arousal neuronal circuits.

11 ions that enable precise assembly of complex neuronal circuits.

12 anticonvulsive drugs that target neurons or neuronal circuits.

13 part of both the circadian and sleep-arousal neuronal circuits.

14 integration of newborn neurons into complex neuronal circuits.

15 critical for development and regeneration of neuronal circuits.

16 e crucial for the appropriate functioning of neuronal circuits.

17 nd learning capacities of single neurons and neuronal circuits.

18 critical to the development and function of neuronal circuits.

19 rucial role in the formation and function of neuronal circuits.

20 mputations performed by anatomically defined neuronal circuits.

21 specialized role in setting up and adjusting neuronal circuits.

22 arget area, where they integrate into common neuronal circuits.

23 a widespread activity-dependent regulator of neuronal circuits.

24 e in maintaining the structural integrity of neuronal circuits.

25 essential functions in the establishment of neuronal circuits.

26 ransmission of Dalpha7-dependent synapses in neuronal circuits.

27 ur understanding of the form and function of neuronal circuits.

28 fects channeling of information in different neuronal circuits.

29 and is a key step in the formation of mature neuronal circuits.

30 he makings and inner workings of neurons and neuronal circuits.

31 hances cognition and induces spinogenesis in neuronal circuits.

32 e important for the coding of information in neuronal circuits.

33 ld facilitate the remodeling of the affected neuronal circuits.

34 mote the maturation of cortical synapses and neuronal circuits.

35 of individual neurons and thus the output of neuronal circuits.

36 rical activity and information processing of neuronal circuits.

37 trieval requires knowledge of the underlying neuronal circuits.

38 sition is essential for the morphogenesis of neuronal circuits.

39 itive function at the level of molecular and neuronal circuits.

40 of axons, dendrites, and synapses that form neuronal circuits.

41 on orchestrated development of hypothalamic neuronal circuits.

42 sult have provided a wealth of insights into neuronal circuits.

43 nt modifications of synaptic strength within neuronal circuits.

44 sive disruption of excitatory and inhibitory neuronal circuits.

45 are critical for the appropriate function of neuronal circuits.

46 and thus their own function within specific neuronal circuits.

47 for the remodeling of aberrant glutamatergic neuronal circuits.

48 To understand computations in neuronal circuits, a model of a small patch of cortex ha

49 To facilitate the dissection of neuronal circuits, a process requiring functional analys

50 Neuronal circuits' ability to maintain the delicate bala

51 that consolidation selectively strengthened neuronal circuits activated by seizures.

52 tion, transforms these signals into adequate neuronal circuit activities, and generates physiological

53 of the influence of different nAChR types on neuronal circuit activity and behavior.

54 em cells, proceeds concurrently with ongoing neuronal circuit activity and is modulated by various ph

55 ptic plasticity" leads to changes in overall neuronal circuit activity, resulting in behavioral modif

56 relationships between activity in specified neuronal circuits and behavior in the larval zebrafish.

57 this review, we provide an update on the key neuronal circuits and cell types mediating conditioned f

58 Genetic approaches to analyzing neuronal circuits and learning would benefit from a tech

59 ynapses is a fundamental mechanism governing neuronal circuits and may form an enduring basis for inf

60 ties, are mutually reinforcing; however, the neuronal circuits and mechanisms that underlie this rein

61 Here we sought to reveal the neuronal circuits and molecular basis of ADHD and its po

62 eurons into our current understanding of the neuronal circuits and molecular mechanisms of the LHA th

63 arned in trace conditioning, recruiting more neuronal circuits and molecular mechanisms than in delay

64 Questions remain regarding which neuronal circuits and neurotransmitters trigger activati

65 -output relationship are applicable to other neuronal circuits and organisms.

66 ls does not selectively label taste-specific neuronal circuits and reveal local taste receptor gene e

67 ant roles of BDNF in regulating synapses and neuronal circuits and suggest that regulation of presyna

68 he creation of comprehensive network maps of neuronal circuits and systems.

69 crucial for the integration of neurons into neuronal circuits and the maintenance of the architectur

70 rerequisite for the establishment of complex neuronal circuits and their capacity for parallel inform

71 questions in epilepsy, to dissect epileptic neuronal circuits and to develop new intervention strate

72 ween neuronal subtypes drive the assembly of neuronal circuits and underlie the subtype specificity o

73 t D2R dysfunction during adolescence impairs neuronal circuits and working memory, and indicate that

74 system for integrating our understanding of neuronal, circuit and whole-animal dynamics.

75 nt are critical for establishing appropriate neuronal circuits, and disrupted timing of these events

76 d for dissecting complex interactions within neuronal circuits, and for testing ideas about how chang

77 hallenges resulting from ongoing activity in neuronal circuits, and from environmental energetic stre

78 round-breaking discoveries in gene-function, neuronal circuits, and physiological responses.

79 l of gene activity in neurons and integrated neuronal circuits, and provides a surprising link betwee

80 ding of how disease-related states, specific neuronal circuits, and various behavioral assays fit int

81 that the rules for astrocyte engagement in a neuronal circuit are fundamentally altered in a brain di

82 To determine whether some neuronal circuits are affected before others, we used Mo

83 that regulate their assembly into functional neuronal circuits are currently unknown.

84 des of plasticity in vivo are unclear, since neuronal circuits are difficult to manipulate in the int

85 Neuronal circuits are known to integrate nutritional inf

86 on of cost/benefit decisions at the level of neuronal circuits are largely lacking.

87 Cell, Xu et al. elegantly show that parallel neuronal circuits are necessary for two distinct roles o

88 ions needed for survival, yet the underlying neuronal circuits are poorly understood.

89 Neuronal circuits are shaped by experience during critic

90 mental developmental units of the brain, and neuronal circuits are the fundamental functional units o

91 The stereotyped features of neuronal circuits are those most likely to explain the r

92 Synapses, the fundamental unit in neuronal circuits, are critical for learning and memory,

93 neuropsychological scheme units, which have neuronal circuits as functional infrastructure, thus hel

94 Astrocytes are critically important for neuronal circuit assembly and function.

95 of central synapses is a key factor driving neuronal circuit behavior in the vertebrate CNS.

96 n is critical for unraveling the function of neuronal circuits but is challenging due to the limited

97 Animal behaviour arises from computations in neuronal circuits, but our understanding of these comput

98 tal component of one of the first discovered neuronal circuits, but their function in motor control h

99 y accompanied by plastic changes in specific neuronal circuits, but these are still poorly defined.

100 ed inhibition and excitation of two separate neuronal circuits by a single interneuron suggests a uni

101 transmitter release in the assembly of early neuronal circuits by assaying transcriptional identity,

102 emory assume that memories are maintained in neuronal circuits by persistent synaptic modifications i

103 lly affects the processing of information in neuronal circuits by reversibly changing the effective s

104 fiber system (GFS), a simple escape response neuronal circuit, by increasing targeting of the gap jun

105 Complicated neuronal circuits can be genetically encoded, but the un

106 This shows that individual and variable neuronal circuits can behave similarly in normal conditi

107 l, these data demonstrate the specificity of neuronal circuit changes induced by amphetamine, introdu

108 How do the components of neuronal circuits collaborate to select combinations of

109 xonal branching contributes substantially to neuronal circuit complexity.

110 on to connect to several targets, increasing neuronal circuit complexity.

111 te difference in the anatomy or functions of neuronal circuits containing inhibition, two basic motif

112 ations in the early wiring and refinement of neuronal circuits contribute to these deficits.

113 on, and a more detailed understanding of the neuronal circuits contributing to each will provide more

114 ed unprecedented knowledge about the precise neuronal circuits contributing to the expression and rec

115 ration); and within these two ends, specific neuronal circuits control the actual rhythmic pattern of

116 To understand how neuronal circuits control variability, we examined the p

117 ecific mode of regulatory control within the neuronal circuit controlling courtship, even though it i

118 dotropin releasing hormone (GnRH) neurons on neuronal circuits controlling energy balance.

119 us accumbens (NAC) is a critical site in the neuronal circuits controlling reward responses, motivati

120 The establishment of neuronal circuits depends on the guidance of axons both

121 hat the counteracting activities of distinct neuronal circuits determine the sexual identity of the p

122 newly formed spines, which are critical for neuronal circuit development and behavioral improvement

123 Defects of neuronal circuit development and function are thought to

124 Neuronal circuit development and function require proper

125 However, neuronal circuit diagrams typically draw upon anatomical

126 nally, SBC-->L2/3 interneuron-->L5 pyramidal neuronal circuits disinhibited and ENGC<-->L2/3 interneu

127 not selectively label taste quality-specific neuronal circuits due to lateral transfer of the tracer

128 tional connections between neurons to sculpt neuronal circuits during development and throughout adul

129 pses is a critical step in the refinement of neuronal circuits during development of the cerebral cor

130 ory, and it is crucial for the refinement of neuronal circuits during development.

131 ts, which is necessary for the maturation of neuronal circuits during early development.

132 The proper development of neuronal circuits during neuromorphogenesis and neuronal

133 empower novel systems-level understanding of neuronal circuit dynamics and facilitate the design of m

134 wing the genetically controlled formation of neuronal circuits, early firing activity guides the deve

135 wing the genetically controlled formation of neuronal circuits, early firing activity guides the deve

136 e monitoring the activity state of the local neuronal circuit electrophysiologically and optically.

137 ation, maintenance, and function in multiple neuronal circuits essential for important brain function

138 oid hormones can help reestablish functional neuronal circuits following degeneration in the adult br

139 NCE STATEMENT Eye movements rely on multiple neuronal circuits for appropriate performance.

140 essing neurons serve as a component of local neuronal circuits for processing itch sensation in the s

141 ow myelinated axon plasticity contributes to neuronal circuit formation and function.

142 regulation of axon branching is crucial for neuronal circuit formation, yet the mechanisms that cont

143 mechanisms by which glia exert control over neuronal circuit formation.

144 oral dynamics to the static description of a neuronal circuit from single time-point connectomics exp

145 ignaling plays important roles in regulating neuronal circuit function and behavior in C. elegans.

146 r uncovering the roles of GluN2C subunits in neuronal circuit function and in the development of new

147 ur understanding of the relationship between neuronal circuit function and symptoms of schizophrenia,

148 Neuronal circuit function is governed by precise pattern

149 ichannels are both targets and modulators of neuronal circuit function.

150 provides an attractive model system to study neuronal circuit function.

151 native splicing of neurexins is critical for neuronal circuit function.

152 ies that involve inflammatory mechanisms and neuronal circuit functions are ill-defined.

153 cs is essential for the understanding of how neuronal circuits give rise to computations.

154 anding how these properties are encoded by a neuronal circuit has been difficult, and no single molec

155 tat and resource localization, for which the neuronal circuit has been identified.

156 Several hypothalamic nuclei and neuronal circuits have been the focus of many studies se

157 dulation of mitochondrial fusion in specific neuronal circuits impact the metabolic status of an anim

158 to signals with rapidly varying statistics, neuronal circuits implementing predictive coding must al

159 tonigral/striatomesencephalic pathway, a key neuronal circuit implicated in positive 'Go' behavioral

160 A map of a neuronal circuit in a marine worm reveals how simple net

161 ation, structure, and function of a specific neuronal circuit in chicken (Gallus gallus domesticus) w

162 uring the functional dynamics of large-scale neuronal circuits in awake behaving mammals at high spee

163 allows the functional mapping of small local neuronal circuits in awake behaving nonhuman primates.

164 ted viruses that can transsynaptically label neuronal circuits in either the retrograde or anterograd

165 ic causal modelling-to test hypotheses about neuronal circuits in health and disease.

166 science by enabling systematic recordings of neuronal circuits in living animals.

167 Neuronal circuits in the brain help to control feeding b

168 vents in the body, including the activity of neuronal circuits in the brain that are involved in cogn

169 ion disturbs the development and function of neuronal circuits in the brain.

170 establishment of the accurate patterning of neuronal circuits in the brain.

171 n be used to investigate the connectivity of neuronal circuits in the brain.

172 ne drugs may release inhibition within local neuronal circuits in the cerebral cortex that may contri

173 Leptin's effects on BP are mediated by neuronal circuits in the dorsomedial hypothalamus (DMH),

174 ant roles in the formation and plasticity of neuronal circuits in the hippocampus, a brain region of

175 ng how self-initiated behavior is encoded by neuronal circuits in the human brain remains elusive.

176 ions that are essential for the operation of neuronal circuits in the neocortex.

177 rafish as a model to study the role of these neuronal circuits in the regulation of feeding, sleep, a

178 there is growing evidence of alterations in neuronal circuits in the sensory cortex of the mouse mod

179 We have developed computational models of neuronal circuits in the spinal cord that include left a

180 ing, are produced by coordinated activity in neuronal circuits in the spinal cord.

181 nosynaptic tracing has been used to identify neuronal circuits in various parts of the nervous system

182 in imaging signaling in complex tissues and neuronal circuits in vivo.

183 Neuronal circuits in worms, flies, and mammals are organ

184 nt approaches have been utilized to decipher neuronal circuits, including electron microscopy (EM) an

185 and ENGC<-->L2/3 interneuron-->L5 pyramidal neuronal circuits inhibited the initiation of dendritic

186 entifying signaling mechanisms that underlie neuronal circuit integration in the adult brain, we have

187 shroom body of the insect brain represents a neuronal circuit involved in the control of adaptive beh

188 been characterized in this organism and the neuronal circuits involved are well described.

189 bute to neurochemical imbalances observed in neuronal circuits involved in stress-related disorders s

190 Thus, a tripartite neuronal circuit involving a fast hyperpolarization and

191 ganization of synaptic connectivity within a neuronal circuit is a prime determinant of circuit funct

192 ynaptic homeostatic mechanisms interact in a neuronal circuit is best studied with a combination of e

193 The formation of neuronal circuits is a key process of development, layin

194 Rewiring of excitatory glutamatergic neuronal circuits is a major abnormality in epilepsy.

195 Development of neuronal circuits is controlled by evolutionarily conser

196 Dense connectomic mapping of neuronal circuits is limited by the time and effort requ

197 ether in functional groups or impact similar neuronal circuits is needed to develop rational treatmen

198 -membrane channels, whose functional role in neuronal circuits is still unsettled.

199 ration of a subset of excitatory synapses in neuronal circuits is sufficient to generate permanent co

200 lve activation of premotor spinal excitatory neuronal circuits is unknown.

201 Understanding of the underlying neuronal circuits is, therefore, of considerable clinica

202 Oscillating neuronal circuits, known as central pattern generators (

203 d manipulate memory function at the cell and neuronal circuit level has spurred an explosion of inter

204 propose that dysfunction at the synaptic and neuronal circuit levels may underlie some episodic neuro

205 Neuronal circuit mapping using electron microscopy deman

206 tic tracing has become a standard method for neuronal circuit mapping, and is applied to virtually al

207 nologies are powerful experimental tools for neuronal circuit mapping.

208 he stimulus arises from shared input but the neuronal circuit mechanisms that result in these noise c

209 Here, we propose a neuronal circuit model with recurrent connections that p

210 Specific neuronal circuits modulate autonomic outflow to liver an

211 tures or execute well-timed motor sequences, neuronal circuits must transform streams of incoming spi

212 n neuronal-glial function within hippocampal neuronal circuits of relevance to cognitive processing i

213 ty evoked by drugs of abuse in the so-called neuronal circuits of reward has been proposed to underli

214 The neuronal circuits of the basolateral amygdala (BLA) are

215 Developing neuronal circuits often undergo a period of refinement t

216 ngth, neuromodulatory substances reconfigure neuronal circuits, often massively altering their output

217 The discovery is that neuronal circuits operating reflexively regulate innate

218 of statistical regularities incorporated in neuronal circuits over a lifetime.

219 ongate, and precisely connect new functional neuronal circuits over long distances.

220 Owing to the complexity of neuronal circuits, precise mathematical descriptions of

221 lie adaptive behavior by rearranging the way neuronal circuits process information.

222 Neuronal circuits produce self-sustaining sequences of a

223 These findings illustrate that neuronal circuit properties can be modulated by adjustin

224 To achieve this, it is critical that neuronal circuits provide information about short-term c

225 ontaining electrical synapses could underlie neuronal circuit reconfiguration via changes in brain en

226 ht Wnt signaling as a targetable pathway for neuronal circuit recovery after synapse degeneration.

227 To investigate a role for MeCP2 in neuronal circuit refinement and to identify activity-dep

228 The assembly and function of neuronal circuits rely on selective cell-cell interactio

229 es of astrocyte Ca(2)(+) signaling in mature neuronal circuits remain unclear.

230 Neuronal circuits required for aversive learning have be

231 Understanding information flow through neuronal circuits requires knowledge of their synaptic o

232 balance between excitation and inhibition in neuronal circuits resulting in a persistent hyperexcitab

233 otonergic innervation of the cortical-limbic neuronal circuit, RGS6 exerts powerful anxiogenic and pr

234 utations on millisecond timescales, but some neuronal circuits set behavioral states over long time p

235 ntral pattern generators, are more tractable neuronal circuits specialized to generate rhythmic movem

236 hering the neuronal code--the rules by which neuronal circuits store and process information--is a ma

237 Here, we report a neuronal circuit that allows Drosophila larvae to overco

238 stral cell type, a progenitor to the complex neuronal circuit that integrates sensory information and

239 From these data we propose a neuronal circuit that may be suited to stabilize the int

240 e physiological properties of lLNvs and on a neuronal circuit that may provide visual information to

241 n of Caenorhabditis elegans is mediated by a neuronal circuit that produces coordinated sinusoidal mo

242 l establishment of OLIG1 lineage-derived ARH neuronal circuits that are critical for leptin-mediated

243 st that it is likely governed by features of neuronal circuits that are shared across the visual cort

244 hieved through the coordinated regulation of neuronal circuits that control a wide range of physiolog

245 Understanding the neuronal circuits that control and regulate GA is centra

246 In the effort to define genes and specific neuronal circuits that control behavior and plasticity,

247 expressing neurons are key components of the neuronal circuits that control food intake and energy ho

248 Motoneurons are not mere output units of neuronal circuits that control motor behavior but partic

249 n becomes the internal CNS reference for the neuronal circuits that control motor commands.

250 Neuronal circuits that control vocalization and breathin

251 s could have functional consequences for the neuronal circuits that express them.

252 llowed investigators to begin to dissect the neuronal circuits that generate behavior in the adult.

253 The neuronal circuits that link the SC to spatial attention

254 this variability to ensure the formation of neuronal circuits that maintain constant retinal coverag

255 reflect profound disruptions of activity in neuronal circuits that mediate awareness and cognition.

256 Our findings reveal that the neuronal circuits that mediate fear and anxiety overlap

257 abolic hormone receptors and have identified neuronal circuits that mediate the action of these hormo

258 t elicit robust attraction responses and the neuronal circuits that mediate this behavior have not be

259 ponding and its related pathologies, but the neuronal circuits that orchestrate these interactions ar

260 nvolved in the maintenance and plasticity of neuronal circuits that play a role in learning.

261 We built a set of simple, plausible neuronal circuits that produce DS cells via different me

262 Immune cell activation stimulates neuronal circuits that regulate innate and adaptive immu

263 Central neuronal circuits that relay stress information include

264 gene control the development and function of neuronal circuits that underlie male-specific behaviors

265 pport for one prominent hypothesis, based on neuronal circuits, that proposes the principal neocortic

266 Although vulnerable neurons are embedded in neuronal circuits, the contributions of their synaptic p

267 ient to develop specialized left lateralized neuronal circuits, thereby pointing to an early onset an

268 activation of astrocytes switches the local neuronal circuit to this slow-oscillation state.

269 he role that RCs perform in one of the first neuronal circuits to be discovered.

270 l for brain development and the responses of neuronal circuits to environmental challenges.

271 ture to identify the specific adaptations of neuronal circuits to environmental changes.

272 the healthy brain, from sculpting developing neuronal circuits to guiding learning-associated plastic

273 represents an ideal strategy for rebuilding neuronal circuits to improve functional recovery after s

274 nsorimotor processing relies on hierarchical neuronal circuits to mediate sensory-driven behaviors.

275 l signals with multiple interrelated central neuronal circuits to produce appropriate levels of food

276 by regulating synaptic function and allowing neuronal circuits to respond dynamically to experience.

277 Here, we review evidence for a bias in neuronal circuits toward temporal coding and the coexist

278 In the idling brain, neuronal circuits transition between periods of sustaine

279 In many regions of the developing brain, neuronal circuits undergo defined phases of enhanced pla

280 has provided a comprehensive picture of the neuronal circuit underlying the formation of fear memori

281 r whether distinct neurons modulate specific neuronal circuits underlying particular types of behavio

282 tors were also of influence, suggesting that neuronal circuits underlying the development of addictio

283 ive tool to eliminate GABAergic neurons from neuronal circuits underpinning high-order behaviors and

284 imulate motion detection well, but the exact neuronal circuits undertaking these tasks remain elusive

285 We show that AGRP neuronal circuits use a segregated, parallel, and redund

286 er a way to probe the functionality of human neuronal circuits using physiological sensory stimuli.

287 but instead maintains a plastic hippocampal neuronal circuit via the continuous addition of immature

288 e elucidated the structure and physiology of neuronal circuits, we still only have a very limited und

289 ed d-serine, suggesting localized effects on neuronal circuits where DAAO can exert a neuromodulatory

290 Further, we delineate a sex-specific neuronal circuit wherein the P1 neurons encoding increas

291 ning leads to the development of specialized neuronal circuits, which allow the execution of fast and

292 gic neurotransmission could lead to abnormal neuronal circuits, which may contribute to neurological

293 ing mGluR5 expression could lead to abnormal neuronal circuits, which may contribute to neurological

294 s, a divergent molecular mechanism regulates neuronal circuit wiring in the Drosophila brain, partly

295 o inhibitory synapses form the hardwiring of neuronal circuits with receptors of a different composit

296 t enable the analysis of genetically defined neuronal circuits with unprecedented specificity and pre

297 ion, supporting the existence of a locomotor neuronal circuit within these MRF in behaving primates.

298 Research has identified distinct neuronal circuits within the basolateral amygdala (BLA)

299 l cord requires the computation of the local neuronal circuits within the same segments as well as th

300 ave prevented the removal of astrocytes from neuronal circuits without changing other important condi