ライフサイエンスコーパス: neuronally

1 cue experiments indicate that cmpy functions neuronally.

2 coexpression of brain slo1 channels with the neuronally abundant BK(Ca) channel beta(4) subunit.

3 MTG is expressed neuronally and detected in the synaptic cleft, and is re

4 -27 is localized to synapse-rich regions pan-neuronally and is also expressed in intestinal cells.

5 The extensive presence of neuronally-associated Cx36 in brainstem auditory structu

6 Neuronally based symptoms depend on the organ in which t

7 Neuronally coexpressed ELAV/Hu proteins comprise a famil

8 Loss of Pbx1 expression in neuronally committed neuroblasts in the rostral migrator

9 In the neuronally derived A1A1 cell line, which expresses both

10 in the brain that can respond to a number of neuronally derived and circulating transmitters and meta

11 gate the properties and function of TRPC4 in neuronally derived cells, we transiently expressed mouse

12 eceptor, but not store-operated, channels in neuronally derived cells.

13 re important for transcriptional activity in neuronally derived cells.

14 CX3CL1, the neuronally derived cognate ligand for CX3CR1, signals bo

15 active or inactive mutants was induction of neuronally derived components of the classic complement

16 d Ca(2+) entry via Ca(v)1A served to inhibit neuronally derived Hedgehog signals, as evidenced by dat

17 Activation of MuSK by agrin, a neuronally derived heparan-sulfate proteoglycan, and LRP

18 ll-length Abeta, including toxicity toward a neuronally derived human cell line, activation of caspas

19 on requires, among others proteins, Agrin, a neuronally derived ligand, and the following muscle prot

20 rescent-labeled PrP-res was used to infect a neuronally derived murine cell line (SN56) and adult ham

21 cted enzyme that catalyzes the hydrolysis of neuronally derived N-acetylaspartate (NAA) to acetate an

22 hysiologically S-nitrosylated by endogenous, neuronally derived nitric oxide (NO).

23 nuclear proteins that completely depends on neuronally derived nitric oxide.

24 Thus, neuronally derived NO and cardiac inhibitory G protein a

25 he aggressive behavior caused by the lack of neuronally derived NO is not known.

26 These results indicate that neuronally derived NO mediates, in part, MPTP-induced ne

27 These findings suggest that neuronally derived NPY accelerates the early response to

28 osome preparations also allowed detection of neuronally derived peptides (23 positively identified) w

29 at the latter method increased the number of neuronally derived peptides positively identified by app

30 which fixes tissue, allows identification of neuronally derived peptides whereas similar analysis of

31 A total of 39 novel neuronally derived peptides, including some originating

32 ation in rats: a transient early increase in neuronally derived plasma NPY and increase in platelet N

33 of the unique coupling of Ca(2+) channels to neuronally derived polarity cues.

34 Other neuronally derived proteins, but not total protein, were

35 To further define the role of neuronally derived TNF-alpha during early AD-like pathol

36 Neuronally derived XBP-1s was sufficient to rescue stres

37 that the observed effect is NO mediated and neuronally derived.

38 These effects are specific to neuronally-derived proteins, which suggests they are lik

39 calpastatin overexpressing (CST1) cells were neuronally differentiated and apoptosis-induced with sta

40 sociated with 14-3-3 zeta when the cells are neuronally differentiated by nerve growth factor.

41 but were remarkably effective in doing so in neuronally differentiated cells.

42 In neuronally differentiated embryonic stem (ES) cells, pat

43 e study structural aspects of integration of neuronally differentiated human NSCs in the motor circui

44 in a WT background, leads to early onset of neuronally differentiated medulloblastomas (MBs) in a p5

45 2C interferes with expression of NR1 mRNA in neuronally differentiated P19 cells.

46 such findings with other retinal neurons or neuronally differentiated PC-12 cells.

47 of IAPs to stringently regulate apoptosis in neuronally differentiated PC12 and primary cells.

48 on site was altered upon C-CGB expression in neuronally differentiated PC12 and SHSY5Y cells.

49 1 (HSV-1) reactivation were identified using neuronally differentiated PC12 cells (ND-PC12 cells) in

50 serum from naive PC12 cells and of NGF from neuronally differentiated PC12 cells and sympathetic neu

51 the expression of the fragment in the ER of neuronally differentiated PC12 cells attenuated agonist-

52 ICP10 but not p139 protected neuronally differentiated PC12 cells from death due to n

53 d CPP32-like enzymatic activity in naive and neuronally differentiated PC12 cells that had been depri

54 retation of our FDAP data (from processes of neuronally differentiated PC12 cells) in light of the he

55 In neuronally differentiated PC12 cells, sPLA(2)-X was pref

56 ry, Western blotting, and calcium imaging in neuronally differentiated PC12 cells.

57 We found that exposure of neuronally differentiated SH-SY5Y cells to AM, OT and PT

58 d miRs, miR-146a was strongly upregulated in neuronally differentiated when compared with miR-146a ex

59 Neuronally differentiated wild-type and GD3S(-/-) ES cel

60 We examined the neuronally directed effects of the retinoid X receptor a

61 d lines of Caenorhabditis elegans expressing neuronally directed human LRRK2.

62 ined activity of two molecularly related but neuronally distinct hygrosensing systems.

63 However, neuronally driven expression of the mutant FMRP is unabl

64 hese and previous studies, we postulate that neuronally enriched Bace1 cleaves neuregulin-1 and that

65 esses a cohort of hundreds of genes that are neuronally enriched but are not specific to a single neu

66 eased in a gene-targeted mouse mutant of the neuronally enriched KLC1 gene.

67 Protein 4.1N is a neuronally enriched member of the 4.1 family of cytoskel

68 new kinesin-like proteins, we identified two neuronally enriched mouse kinesins that provide insight

69 Here we demonstrate that PARP6, a neuronally enriched PARP that catalyzes MARylation, regu

70 tissue-specific F-actin binding protein), a neuronally enriched protein of 1,095 amino acids that co

71 Neuronally enriched RGS4 plays a critical role attenuati

72 Calcineurin, a neuronally enriched, calcium-stimulated phosphatase, is

73 have focused on tomosyn, a highly conserved, neuronally enriched, syntaxin-binding protein that has b

74 One of these light chains is neuronally enriched, while another shows ubiquitous expr

75 how that buffering astrocyte Ca(2+) inhibits neuronally evoked capillary dilation, that astrocyte [Ca

76 We have created transgenic mice that neuronally express the baculoviral caspase inhibitor p35

77 Vertebrate orthologs of Drosophila MICAL are neuronally expressed and also interact with vertebrate p

78 Neuronally expressed auxilin and ubiquitously expressed

79 d that maintenance of this response requires neuronally expressed calcium activator for protein secre

80 1 loads, weak brain immune responses, lacked neuronally expressed changes in neocortex and exhibited

81 study, we report the expression pattern for neuronally expressed connexin 35b (cx35b), the zebrafish

82 erminal domain that affects trafficking of a neuronally expressed DEG/ENaC.

83 Hyperactivation of neuronally expressed DEG/ENaCs that conduct both Na+ and

84 nteracting proteins, we identified APLIP1, a neuronally expressed Drosophila homolog of JIP-1, a JNK

85 n mice in which the kinase activity of three neuronally expressed EphBs can be rapidly, reversibly an

86 Neuronally expressed family members include the C. elega

87 (shot) encodes an evolutionarily conserved, neuronally expressed family of rod-like proteins require

88 These phenotypes suggest that the neuronally expressed Fgf14 gene is essential for regulat

89 we replaced the goa-1 gene, encoding the pan-neuronally expressed G-protein subunit GOA-1, with a deg

90 In particular, some neuronally expressed genes appear refractory to dsRNA-me

91 s have been identified, de novo mutations in neuronally expressed genes are a common scenario.

92 enetic screen to assess the function of >400 neuronally expressed genes for a role in the homeostatic

93 n and assessed the function of more than 250 neuronally expressed genes for a role in the homeostatic

94 uronal phenotype, including the induction of neuronally expressed genes such as vgf.

95 tion of the alternative splicing of 17 other neuronally expressed genes were investigated, and no eff

96 ar cis-regulatory architecture of individual neuronally expressed genes, we have defined a conserved

97 esponse, regulates the transcription of many neuronally expressed genes.

98 licing determines the protein output of most neuronally expressed genes.

99 tions to address the function of neurons and neuronally expressed genes.

100 ed in brain-expressed genes, particularly in neuronally expressed genes; most of this elevation arose

101 NKAIN family members are neuronally expressed in multiple regions of the mouse br

102 Here we show that TMEM106B is neuronally expressed in postmortem human brain tissue, a

103 r 1 d in culture, CHO cells synthesizing the neuronally expressed isoform with an eight amino acid in

104 iochemical and biophysical properties of the neuronally expressed isoforms with that of the ubiquitou

105 TRAAK (also known as KCNK4) ion channels are neuronally expressed members of the two-pore domain K(+)

106 This neuronally expressed microRNA was not only suppressed by

107 nsory organ lineage is controlled by the non-neuronally expressed mir-279/996 cluster, with a majorit

108 ted glial cells, which was then activated by neuronally expressed MMP14.

109 PEP-19 is a 7.6 kDa neuronally expressed polypeptide that contains a single

110 Here, we identify R7BP, a novel neuronally expressed protein that binds R7-Gbeta5 comple

111 The diffusible signal molecule Slit and the neuronally expressed receptor Robo mediate growth cone c

112 suggests that this process is dependent upon neuronally expressed regulatory factors.

113 All four encode neuronally expressed RNA binding proteins conserved in D

114 Connector enhancer of KSR-2 (CNK2) is a neuronally expressed scaffold recently implicated in non

115 ions, in neuronal-synaptobrevin (n-syb), the neuronally expressed synaptobrevin gene in Drosophila.

116 Neuronally expressed Syt I4C rescues the syt I null muta

117 A search for additional neuronally expressed T cell receptor components has reve

118 (A)Rs in response to TNFalpha is mediated by neuronally expressed TNF receptor 1 and requires activat

119 A number of neuronally expressed tubulin genes are associated with a

120 Given that TUBB4 is a neuronally expressed tubulin, our results imply abnormal

121 ransgenic complementation of ax(J) mice with neuronally expressed ubiquitin prevents early postnatal

122 (15q11-q13/7qC) and GTL2(14q32.2/12qF1), are neuronally expressed, localized to imprinted loci and in

123 Here we survey the role of neuronally expressed, paralogous tumor necrosis factor r

124 The neuronally expressed, proton-gated acid-sensing ion chan

125 a small novel gene family which is primarily neuronally expressed.

126 e changes were attenuated in transgenic mice neuronally expressing the general caspase inhibitor prot

127 ed with 2DG, the majority of the slices were neuronally functional after activation by Glu.

128 Neuronally generated nitric oxide is a mediator of brain

129 e-dependent membrane currents similar to the neuronally guided BMSCs, although with smaller amplitude

130 rix genes were selectively down-regulated in neuronally guided BMSCs.

131 based and model-free reinforcement learning, neuronally implemented in frontostriatal circuits involv

132 ome correlations were explicitly represented neuronally in right midinsula with a learning prediction

133 g the gene encoding these channels prevented neuronally induced vasodilation and suppression of arter

134 art by brain lipid-binding protein (BLBP), a neuronally induced, radial glial molecule, previously sh

135 manner, heme-derived carbon monoxide affects neuronally mediated activities.

136 Moreover, our data suggest that neuronally mediated BOLD signal variance generally incre

137 alpha1, AMPK activity in BAT and muscle are neuronally mediated, as they are present in neuron- but

138 imental RIPC has two temporal components, is neuronally mediated, is induced by limb ischemia, and re

139 nd late (prolonged) phase, both of which are neuronally mediated.

140 to show that the poststimulus fMRI signal is neuronally modulated.

141 g RNA used to reduce Luman expression either neuronally or just axonally significantly impaired the a

142 nonphosphorylatable UNC-18 S322A, either pan-neuronally or specifically in AFD thermosensory neurons,

143 ytic interaction in the spinal cord by which neuronally produced CXCL13 activates astrocytes via CXCR

144 In particular, neuronally produced NO appears to play a role in rapid u

145 resents the first demonstration in vivo that neuronally produced NO is an important factor in the con

146 n, but the signaling pathways that program a neuronally protective or destructive phenotype in microg

147 isoforms specifically activates splicing of neuronally regulated exons.

148 In addition, baroreflex-mediated, ie, neuronally regulated, bradycardia after phenylephrine wa

149 adder, indicating a second mode of action of neuronally released ATP.

150 ned to determine the role of the reuptake of neuronally released glutamate in lactate delivery to the

151 cells play an important role in sequestering neuronally released glutamate via Na+-dependent transpor

152 pic glutamate receptors on the astrocytes by neuronally released glutamate.

153 asked where different schema components are neuronally represented and converge during retrieval.

154 ored the biological importance of particular neuronally responsive regions within the promoter by cre

155 Neuronally restricted expression and male germline mosai

156 However, the neuronally restricted expression of CaBP and its inhibit

157 These results demonstrate that the neuronally restricted expression of the human beta2 adre

158 PTB, the only change was upregulation of the neuronally restricted nPTB, resulting from decreased ski

159 nal-like exocytotic tissues, consistent with neuronally restricted symptoms of REEP1 genetic disorder

160 ms, we here demonstrate that angiogenin is a neuronally secreted factor that is endocytosed by astrog

161 nds on a well-orchestrated dialogue in which neuronally secreted misfolded proteins activate microgli

162 Here, we show that the neuronally secreted protein Neuregulin-1 (NRG1) fulfills

163 ed by disease-linked mutations and suggest a neuronally selective mechanism through which TDP-43 muta

164 eta2 subunit combination, making it the most neuronally selective nicotinic antagonist characterized

165 Connexin-36 is a neuronally specific protein associated with low-resistan

166 MuSK becomes phosphorylated when exposed to neuronally synthesized isoforms of agrin.

167 s in the limb; invoking additional roles for neuronally synthesized RA in motor neuron maintenance an

168 To test this hypothesis in vivo, we employed neuronally targeted expression of three human FMR1 trans

169 Ubiquitous or neuronally targeted mtg RNA interference (RNAi) similarl

170 GCLm) subunit of this enzyme, in a global or neuronally targeted pattern.

171 Two are expressed pan-neuronally, while the others are restricted in their exp