ライフサイエンスコーパス: neuropil

1 ong-lasting reduction in neuronal processes (neuropil).

2 g (endothelial cells) and brain (neurons and neuropil).

3 al neuron models spread across a cylindrical neuropil.

4 o the mitral cells innervating this specific neuropil.

5 flying moths, which invest more in olfactory neuropil.

6 trocytes and are likely to reflect a loss of neuropil.

7 ironment of excitation and inhibition in the neuropil.

8 d restricted terminal endings inside the GLv-neuropil.

9 entromedial-low pattern in the antennal lobe neuropil.

10 he primary phagocytic cell type in the pupal neuropil.

11 e SG, the staining was mostly diffuse in the neuropil.

12 bula plate of this crab is a small elongated neuropil.

13 ession was similar throughout the glomerular neuropil.

14 minate homotopically within the external GLv-neuropil.

15 neurons functionally coupled to spinal cord neuropil.

16 and accurately reconstruct large volumes of neuropil.

17 bscured due to the complexity and density of neuropil.

18 rborization fields within the same region of neuropil.

19 mus, strong GFP signals were detected in the neuropil.

20 st expression in hippocampal and neocortical neuropil.

21 c branches into defined volumes of the brain neuropil.

22 K in both sensory neuron somata and synaptic neuropil.

23 ortex, dendrites branch mainly in the dorsal neuropil.

24 mmediate PKA activation only in the synaptic neuropil.

25 nriched on neuronal somata and in the medial neuropil.

26 ommercial antibodies bound more often to the neuropil.

27 nt darkness restores timely neurogenesis and neuropil.

28 nse by non-neuronal cells in the surrounding neuropil.

29 tinal inner plexiform layer (IPL) and tectal neuropil.

30 nonoverlapping volumes of the diffuse motor neuropil.

31 an evolutionary conserved function for this neuropil.

32 were also found in oligodendrocytes and the neuropil.

33 to specific depths or layers of their target neuropil.

34 cific region of the axon trunk, near a motor neuropil.

35 roduce similar increases in FUNCAT in tectal neuropil.

36 d their astrocytes poorly infiltrate the CNS neuropil.

37 ualization of proteins, cell populations and neuropil.

38 heres also targeted distinct layers of these neuropils.

39 d further target a restricted set of distant neuropils.

40 regions between the more classically defined neuropils.

41 of the superior protocerebrum into discrete neuropils.

42 where they send off side branches in dorsal neuropils.

43 ties in the organization of their optic lobe neuropils.

44 continuity between larval and adult sensory neuropils.

45 also identifies plasticity in several other neuropils.

46 nts of the central complex and its accessory neuropils.

47 tion and in the local micro-structure of the neuropil?

48 Our work characterizes 21 well-defined neuropils (19 paired, 2 unpaired), as well as all synapt

49 stribution of PV immunoreactivity within the neuropil, (2) the properties of dendritic shafts of PV-I

50 a (SNr) also harbored a significant level of neuropil A(2A) R immunoreactivity.

51 sted the hypothesis that the distribution of neuropil across areas of the neocortex of humans differs

52 Olfactory neuropiles across different phyla organize into glomerul

53 The central complex is a group of modular neuropils across the midline of the insect brain.

54 gM, IgG, and IgA antibodies are found in the neuropil adjacent to the lesion.

55 Neuropathologically, the distribution of neuropil aggregates and nuclear accumulation of N-termin

56 ently in the cortex than in the striatum and neuropil aggregates appear earlier than mutant htt accum

57 d without the Snell genotype, whereas nigral neuropil aggregates were diminished in bigenic HD knock-

58 4 postcrush, and reinnervating the olfactory neuropil almost back to normal within 2 weeks.

59 her impairing astrocytic infiltration of the neuropil alters synaptic connectivity.

60 uired for branch extension into the synaptic neuropil and anchoring of cell bodies at the neuropil bo

61 ition of amyloid-beta peptide (Abeta) in the neuropil and around the blood vessels, and formation of

62 Neuropil and cell layer volumes were reduced in cornu am

63 hippocampal dentate gyrus neurons somata and neuropil and hippocampus proper (CA3, CA1) of the epilep

64 fine cellular processes that infiltrate the neuropil and interact with synapses.

65 s to punctate aggregates in central synaptic neuropil and neuromuscular junction (NMJ) presynaptic te

66 erved extensive punctate staining within the neuropil and on the membrane of specific groups of neuro

67 ing functionally segregates large volumes of neuropil and that these transients are not suited for re

68 the burden of oligomeric amyloid-beta in the neuropil and that this synaptotoxic oligomerized peptide

69 spectrum of outputs from the central complex neuropils and circuits involved in numerous behaviors.

70 that receives projections from the eyestalk neuropils and compound retina.

71 omatically identify functional units such as neuropils and fiber tracts.

72 often coinnervate the same local neuropil or neuropils and further target a restricted set of distant

73 rential localization of the receptor in some neuropils and neurons indicates the presence of possible

74 ent signal intensity in some distinguishable neuropils and neurons.

75 rgue for regional clonal development of both neuropils and neuropil connectivity throughout the Droso

76 ed genetic program leading to interconnected neuropils and nuclei that populate the midline of the fo

77 s were normally high relative to surrounding neuropil, and exhibited a time-dependent decrease during

78 logic injury to individual structures in the neuropil, and have identified mitochondrial dysfunction

79 plexippus), which invests heavily in visual neuropil, and night-flying moths, which invest more in o

80 tatus epilepticus, and antibodies to unknown neuropil antigens.

81 First, segmental neuropiles are established which then become connected b

82 y of the interconnections obscures how these neuropils are established and interconnected through dev

83 n debated whether these second-order sensory neuropils are homologous or whether they have evolved in

84 n the CeA and increased CRF-IR in the dlBnST neuropil, are consistent with a mechanism in which the e

85 neuronal network of cell bodies and synaptic neuropils arranged in distinct layers.

86 eated HD mice showed microvacuolation in the neuropil, as well as gliosis and huntingtin aggregates,

87 to identify molecular mechanisms leading to neuropil asymmetry, and uncovered a novel interaction be

88 t volume, we sampled a small fraction of the neuropil belonging to an adult ganglion.

89 neuropil and anchoring of cell bodies at the neuropil border.

90 The lack of clearly determined neuropil boundaries has made it difficult to document pr

91 ogy and antibodies with a similar pattern of neuropil brain immunostaining were selected for autoanti

92 alterations in numbers of glia and extent of neuropil, but not numbers of neurons, in CA1 and DG.

93 l regions did not display significantly more neuropil, but the primary auditory cortex had a lower ne

94 insects possess large second-order olfactory neuropils called, respectively, hemiellipsoid bodies and

95 mass spectrometry, we demonstrate that these neuropils can be characterized by their specific neurope

96 t that despite many evolved modifications of neuropil centers within arthropod brains and ganglia, hi

97 Paired lobed or dome-like neuropils characterize the first brain segment (protocer

98 rther show that the relative size of sensory neuropils closely mirror interspecific variation in sens

99 adult antenna project into the centrolateral neuropil column of the anterior SEZ, creating the antenn

100 ate process extension so as to insulate each neuropil compartment.

101 nput to the central complex, a collection of neuropil compartments important for visually guided beha

102 les (fascicles) which interconnect different neuropil compartments.

103 nal clonal development of both neuropils and neuropil connectivity throughout the Drosophila central

104 The neuropil contains at least two classes of tangential ele

105 ocyte membranes subsequently infiltrated the neuropil coordinately with synaptogenesis, and astrocyte

106 D-95 puncta are enriched in the most lateral neuropil corresponding to distal dendrites while gephyri

107 erves, and a lateral protocerebral olfactory neuropil corresponds to the malacostracan hemiellipsoid

108 otor neurons, suggesting that the structured neuropil could provide a framework for the development o

109 , the neural composition of crustacean optic neuropils deeper than the lamina is mostly unknown.

110 ations of diffusion within the reconstructed neuropil demonstrate that the rate of diffusion of neuro

111 organ causes differences in gene expression, neuropil density, and connectivity of the left and right

112 h as developmental waves of differentiation, neuropil development, lineage tracing and hierarchies of

113 The overall size of the lamina neuropil did not correlate with the size of its LMCs.

114 tracts of the above-mentioned lineages, the neuropil differentiates during the first 2 days of the p

115 ynamics of both single cells and superficial neuropil distributed across the majority of dorsal corte

116 These species differences in neuropil distribution may offer insight into the neural

117 lineage tracts also demarcate seven columnar neuropil domains (ventromedial, ventro-lateral, centrome

118 of the SEZ, as well as discrete longitudinal neuropil domains within each SEZ neuromere.

119 We conclude that Ulk2 activity promotes neuropil elaboration while Kctd12 proteins limit Ulk2 ac

120 k2 or mutation of kctd12 genes causes excess neuropil elaboration.

121 ession of Kctd12 proteins reduces asymmetric neuropil elaboration.

122 olume of the mushroom bodies, a higher order neuropil essential for learning and memory in Hymenopter

123 questions of how the architecture of visual neuropils evolved among different phyla remain open.

124 This establishment of neuropil excitatory-inhibitory structure largely precede

125 The antennal lobe neuropil expressed the cell surface marker semaphorin 1a

126 Resolving whether neuropil expression represents presynaptic, postsynaptic

127 in the host brain they were seen in neurons, neuropil, extracellular matrix, and blood vessels.

128 eir close association with specific SATs and neuropil fascicles, as described in the accompanying pap

129 image analysis techniques, we quantified the neuropil fraction from both hemispheres in six cytoarchi

130 but the primary auditory cortex had a lower neuropil fraction than other areas.

131 ntoinsular cortex had a significantly higher neuropil fraction than the other areas.

132 Carlo model of a realistic three-dimensional neuropil fragment containing 54 excitatory synapses.

133 eometry of 180 mum(3) of rat CA1 hippocampal neuropil from serial electron microscopy and corrected f

134 ophila visual system, astrocyte-like medulla neuropil glia (mng) variants acquire stereotypic morphol

135 We document the extension of neuropil glia around the nascent EB and BU, and analyze

136 miting glutamate escape into the surrounding neuropil, GLT-1 preserves the spatial specificity of syn

137 The mushroom body neuropils have been identified as a crucial memory circu

138 Laser-induced lesions of the tectal neuropil impaired the behavior.

139 overall synapse density is maintained in the neuropil, implicating synapse loss commensurate with the

140 onized ongoing activity in the mushroom body neuropil in alive and awake flies before and after learn

141 sel wall disruption and abnormal surrounding neuropil in patients with type 2 diabetes and dementia,

142 rstanding the distribution of plaques in the neuropil in relation to the connectivity pattern of the

143 mmunoreactivity was restricted to fibers and neuropil in the analyzed dorsal thalamic nuclei, and pre

144 One of these genes, Ten-a, implicates a neuropil in the central complex of the fly brain as infl

145 CbAST-B1-LI was found in neurons and neuropil in the commissural ganglia (CoGs), in somata in

146 quantified and charted the components of the neuropil in the four deep cerebellar nuclei (DCN) of the

147 the pan-neuronal promotor elav to label the neuropil in the live animal.

148 that humans exhibit a unique distribution of neuropil in the neocortex compared to chimpanzees.

149 The majority of GABA-ir axons and neuropil in the Nudipleura were restricted to the buccal

150 euronal types of the lamina, the first optic neuropil in the stomatopod visual system.

151 the results reveal a very dense and complex neuropil in which several channels of information proces

152 ntal steps generating the eye and its target neuropils in fish and fruit flies supports a homology be

153 the relative volumes of olfactory and visual neuropils in the brain and also in the number and volume

154 alyzed the anatomical organization of visual neuropils in the brain of the praying mantis Hierodula m

155 e neuropeptide repertoire of higher cerebral neuropils in the brain of the red flour beetle Tribolium

156 We examined the development of olfactory neuropils in the hemimetabolous insect Locusta migratori

157 The central complex is a group of modular neuropils in the insect brain with a key role in visual

158 part of the lobula complex, the third optic neuropil, in the optic lobes of insects.

159 st that astrocytes respond to plaque-induced neuropil injury primarily by changing phenotype, and hen

160 the brains of insects is a series of midline neuropils involved in motor control, sensory integration

161 x of the insect brain is a system of midline neuropils involved in transforming sensory information i

162 have delineated how about two-thirds of the neuropil is filled out with dendrites and axons optimizi

163 Four patients (4%) with neuropil labeling suggestive for extracellular antigen r

164 In the first visual neuropil (lamina), which contains a multilayer glial net

165 : (i) entorhinal cortex (ERC) and CA1 apical neuropil layer [CA1-stratum radiatum lacunosum molecular

166 ors for directing their axons to the medulla-neuropil layer M3.

167 processes, as exemplified in the hippocampal neuropil layers and weakly stained pyramidal cell layers

168 the CNS of N. granulata was performed at the neuropil level, with special focus on one of the main st

169 The central complex (CX) is a defined set of neuropils located on the midline of the protocerebrum in

170 Also, somatic versus neuropil location of varicosities suggests that most of

171 The stratified structure of the larval optic neuropil (LON) suggests common organizational principles

172 Using a neuropil marker (the antibody nc82) as a reference of th

173 on occurs without concomitant alterations in neuropil mitochondrial size, as assessed by both array t

174 l framework based on a fiducial reference of neuropil morphology.

175 ogical methods we describe neurons and their neuropils most immediately associated with the stomatopo

176 dly, but only expressed if-1 and cali in the neuropil near hh(+) neurons.

177 used on the accessory medulla (AMe), a small neuropil near the medulla that acts as the master circad

178 ity of subunit expression also varied in the neuropil, neuronal somata, and/or cellular processes in

179 s of five nested neuropils with at least one neuropil not present in the cockroach or locust.

180 rget dendrites and spines in the perisomatic neuropil of CG neurons; (2) GABA is restricted to a spec

181 tions of glia exist in the lamina, the first neuropil of the adult optic lobe: those that arise from

182 Although the extracellular space in the neuropil of the brain is an important channel for volume

183 The auditory neuropil of the bush-cricket Mecopoda elongata is tonoto

184 all cortical layers and within both soma and neuropil of the deprived cortical and brainstem regions.

185 olfactory tubercle where DCL is found in the neuropil of the islands of Calleja (ICj).

186 ir axons into at least six layers within the neuropil of the midbrain tectum.

187 gnus, obscurus, and pallidus and SERT in the neuropil of the pre-Botzinger complex, nucleus ambiguus,

188 sory center located deep in the ventromedial neuropil of the tritocerebrum and mandibular neuromere,

189 symmetric) synapses in the layers 2-3 (L2-3) neuropil of visual (V1) and frontal (FC) cortices of the

190 ensional reconstructions of the optic tectal neuropil of Xenopus laevis tadpoles to detect and quanti

191 f the thoracic ganglia, and ventral part and neuropiles of the abdominal ganglia.

192 itry of the lobula--one of the four, primary neuropiles of the fly optic lobe--performs this visual d

193 from serial-section TEM (ssTEM) of the optic neuropiles of the miniature parasitic wasp Trichogramma

194 including the brain, the midline region and neuropiles of the thoracic ganglia, and ventral part and

195 Establishment of synaptic connections in the neuropils of the developing nervous system requires the

196 Mapping the neuropils of the dung beetle brain is thus a prerequisit

197 assumption that the arthropods' higher order neuropils of the forebrain [the mushroom bodies (MBs) of

198 es ramify in primary antennal-mechanosensory neuropils of the head ganglia.

199 ates, we performed 3D reconstructions of all neuropils of the monarch brain based on anti-synapsin la

200 During embryogenesis, all neuropils of the olfactory pathway transiently expressed

201 We focus on two integrative neuropils of the olfactory pathway, the antennal lobes a

202 The investigated visual neuropils of the praying mantis are highly structured.

203 udied the internal organization of all major neuropils on brain sections, using immunocytochemical st

204 ells at the superficial border of the tectal neuropil, one of which is an emergent population.

205 bustly asymmetric, with dense elaboration of neuropil only in the left lateral subnucleus.

206 tribute axons or dendrites into the CA1-SRLM neuropil, only ERC emerged as a significant predictor of

207 ptic circuits of seven columns in the second neuropil or medulla behind the fly's compound eye.

208 5a, Tm5b, Tm5c, and Tm20 in the second optic neuropil or medulla.

209 ring clones often coinnervate the same local neuropil or neuropils and further target a restricted se

210 from L1, the ON-channel neuron in the first neuropil, or lamina, thus providing a candidate substrat

211 inputs to T5 at their terminals in the third neuropil, or lobula.

212 two types of columnar neurons in the second neuropil, or medulla, that relay input to T4 from L1, th

213 The neuropil organization and the pattern of gamma-aminobuty

214 rt an increasing toxicity in the surrounding neuropil over the clinical course of AD, thereby potenti

215 It scales to large volumes of cortical neuropil, plausibly even whole-brain datasets.

216 In the anteroposterior plane, the neuropil possesses four layers defined by the arborizati

217 period accompanies structural changes in the neuropil, preserving a relatively consistent glutamate c

218 The neuropil provides a proxy measure of total connectivity

219 e the ellipsoid body, a well-known pre-motor neuropil, provides complete rescue.

220 ed a standardized version of the sun compass neuropils, providing reference volumes, as well as a com

221 ence of large tangential neurons exiting the neuropil, reflect the general structure of the insect lo

222 ith development, first within the ventral NL neuropil region and subsequently throughout both the ven

223 e activity was consistently initiated in the neuropil region of the stomatogastric ganglion motor cir

224 leted flies, glia do not properly infiltrate neuropil regions after axotomy and, as a consequence, fa

225 ces with modality-specific, distinct sensory neuropil regions.

226 recedented contrast within the modular brain neuropil, revealing hyperintense signal in synapse-rich

227 In the neuropil, SATs assemble into larger fiber bundles (fasci

228 rosophila larval antennal lobe, an olfactory neuropil similar to the vertebrate olfactory bulb.

229 in receptors delays neurogenesis and reduces neuropil similarly to constant darkness, while addition

230 y species, we identify an asymmetric pair of neuropils situated deep in the fan-shaped body, called t

231 and spike phase were invariant to changes in neuropil size, to morphological heterogeneity, to excita

232 cortex possesses wider minicolumns and more neuropil space than other cortical regions.

233 yses of pro-survival/pro-regeneration genes, neuropil-specific genes, and genes involved in or respon

234 We segmented and traced the neuropil stained with one of two antibodies, one antibod

235 ody staining throughout all cortical layers, neuropil staining is markedly increased and uniform in l

236 Neuropil staining is pronounced and uniform across corti

237 niform across cortical layers and very light neuropil staining.

238 Comparison of neuropil structures between the two dung beetle species

239 thelium to the OB, where they form spherical neuropil structures called glomeruli.

240 irst provide a general overview of the major neuropil structures in the eyestalks lateral protocerebr

241 lineages of the SEZ to the newly established neuropil subdivisions.

242 es a rapid structural re-organization of the neuropil surrounding glutamatergic synapses, which is as

243 In contrast, the neuropil surrounding the two different injured FMN popul

244 loyment of ramified arbors to cover specific neuropil territories to form a stereotyped astroglial ma

245 olocalized to punctate structures within the neuropil that codistributed with foci of proteolytic act

246 Olfactory bulb glomeruli are regions of neuropil that contain input and output processes: olfact

247 fied circumscribed zones of tdTomato-labeled neuropil that correspond to striosomes as verified immun

248 The insect brain can be divided into neuropils that are formed by neurites of both local and

249 Cells in the input neuropil, the calyx, are organized into an array of micr

250 The distinctive midline neuropil, the central complex (CX), is one of the most p

251 A previous study shows that the first optic neuropil, the lamina of the crab Neohelice granulata, po

252 c Tm neurons project axons to a deeper optic neuropil, the lobula, which in insects has been implicat

253 , analysis of glial cell types in the second neuropil, the medulla, has identified at least four type

254 mic filopodial protrusions within the tectal neuropil, the motility of which has previously been show

255 urons that send projections into the central neuropil (thorax).

256 these questions, we examined activity in the neuropil thought to be responsible for visual motion det

257 es were unchanged, whereas only AT8-positive neuropil thread density was statistically higher in AD s

258 characterized by neurofibrillary tangle and neuropil thread deposition, which ultimately results in

259 , AD-like neurofibrillary tangles (NFTs) and neuropil threads (NTs).

260 ongTAR DNA-binding protein (TDP)-43-positive neuropil threads and dystrophic neurites (type C), and i

261 neurofibrillary tangles and less reactive in neuropil threads and extracellular tangles in TPSD and F

262 the development of neurofibrillary tangles, neuropil threads and ghost tangles was rare and likewise

263 rphosphorylated tau pathology in the form of neuropil threads and neurofibrillary tangles and pre-tan

264 Gallyas-positive neuropil threads and oligodendroglial coiled bodies were

265 ing in early pathological inclusions such as neuropil threads and pretangle neurons as well as coloca

266 ical inclusions, neurofibrillary tangles and neuropil threads but only in the patient who came to aut

267 ars, drug users showed a similar increase in neuropil threads compared with controls, but this reache

268 formers in pretangles, neuritic plaques, and neuropil threads in the frontal cortex tissue from AD br

269 Hyperphosphorylated tau positive neuropil threads increased at a faster rate in drug user

270 yperphosphorylated tau positive (AT8, AT100) neuropil threads were significantly increased in the fro

271 ophic neurites surrounding neuritic plaques, neuropil threads, and granulovacuolar degeneration bodie

272 ical inclusions, neurofibrillary tangles and neuropil threads.

273 This ensures tiling of the lamina neuropil through heterotypic interactions.

274 roteins, within the cytoplasm of neurons and neuropil throughout the CNS.

275 antly by exploiting the capacity of cortical neuropil to transit between a gas-like phase with sparse

276 euroarchitecture in situ and allows specific neuropils to be distinguished within the brain to extrac

277 al effects after gene removal on the retinal neuropil together with the consequences of lack of devel

278 revealed consistent differences between the neuropils, underlining that direct peptide profiling by

279 and fast reconstructions of volumes of brain neuropil using ilastik, a software tool for semiautomate

280 th reduced kalirin expression showed reduced neuropil volume in the rodent homologue of the STS.

281 e brain to extract quantitative data such as neuropil volumes.

282 e average synaptic density in the glomerular neuropil was about two synapses/microm(3) .

283 e expression response of presymptomatic SOD1 neuropil was compared with WT.

284 pupal stages the Drosophila melanogaster CNS neuropil was devoid of astrocyte membranes and synapses.

285 ation of mitral cells and their postsynaptic neuropils was found on a larger scale.

286 In an EM reconstruction of hippocampal neuropil we found single axons making two or more synapt

287 capillaries are embedded in the O2-consuming neuropil, we have here examined whether activity-depende

288 ual erythrocytes, to infer Po2 in the nearby neuropil, we report the first non-invasive micron-scale

289 and pursuing their projections into specific neuropils, we unravel the regional development of the br

290 The axons in the Me neuropil were fine or coarsely beaded, and fibers showed

291 Neuropils were three-dimensionally reconstructed from sy

292 ndently of spatial input; they innervate the neuropil where they are generated.

293 The aging brain shows a progressive loss of neuropil, which is accompanied by subtle changes in neur

294 of around 700 somata, surrounding a central neuropil with 3-5 ventral and 2-5 dorsal commissures.

295 selective ultrastructural reconstruction of neuropil with functional and viral circuit mapping, we c

296 CP2, and DPMpl2, connect the posterior brain neuropil with specific layers of the fan-shaped body.

297 f the praying mantis consists of five nested neuropils with at least one neuropil not present in the

298 partite pre-stomodeal brain and nested optic neuropils with extant Malacostraca and Insecta, demonstr

299 ughout both the ventral and dorsal dendritic neuropil, with significantly fewer terminals in the cell

300 fter, TNS impairs PKA activation in synaptic neuropil without affecting the delayed PKA activation in