ライフサイエンスコーパス: neuropilin-1

1 egulate axonal levels of the Sema3A receptor neuropilin 1.

2 moral M1, acting through the SEMA3A receptor neuropilin 1.

3 pecific phosphorylation in vivo, mediated by Neuropilin-1.

4 lar endothelial growth factor receptor-2 and neuropilin-1.

5 otif Arg-Pro-Leu targets VEGF receptor-1 and neuropilin-1.

6 rted effects of tuftsin are mediated through neuropilin-1.

7 al positioning of neuronal cells, reelin and neuropilin-1.

8 was inhibited by antibodies directed against neuropilin-1.

9 ors of sensory pathfinding semaphorin 3A and neuropilin-1.

10 binds specifically to VEGF receptor-1 and to neuropilin-1.

11 olysialylation process than those regions of neuropilin-1.

12 The activity is blocked by anti-neuropilin-1.

13 not completely, nonoverlapping with that of neuropilin-1.

14 n into cancer cells via the interaction with neuropilin-1.

15 its impaired binding to the VEGF co-receptor neuropilin-1.

16 hrough activation of VEGF and its coreceptor neuropilin-1.

17 increased binding of VEGF to its coreceptor neuropilin-1.

18 of domain swap chimeras with sequences from neuropilin-1, a protein for which polysialylation had no

19 GF receptor (VEGF165R) is identical to human neuropilin-1, a receptor for the collapsin/semaphorin fa

20 r to those of others following inhibition of neuropilin-1, a receptor previously implicated in TGFbet

21 rnalized into cultured tumor cells through a neuropilin-1-activated pathway and triggered cell death.

22 finity for its primary receptor and binds to neuropilin-1, activating a tissue penetration pathway th

23 ration of siRNAs against the Sema3A receptor neuropilin-1 also resulted in polarization defects in vi

24 Patients with low baseline expression of neuropilin-1 also showed a trend toward improved overall

25 Syb2 associated with Neuropilin 1 and Plexin A1, two essential components of

26 izes the extrinsic pathway and requires both neuropilin 1 and plexin A3.

27 ways by antibodies to neuropilin-1, and that neuropilin-1 and -2 can form homo- and heterooligomers t

28 jections in vivo correspond to those seen in Neuropilin-1 and -2 mutants.

29 opilin-2 oligomers, and the Sema E signal by neuropilin-1 and -2, either as homo- or heterooligomers.

30 is, we show that sympathetic axons coexpress neuropilin-1 and -2, that their responses to Sema III, S

31 inity antagonist, TKPPR, bind selectively to neuropilin-1 and block vascular endothelial growth facto

32 ded to associated cues of axon guidance like neuropilin-1 and F-actin.

33 First, aged Tregs had high expression of neuropilin-1 and Helios, and had a broad Vbeta repertoir

34 naling by a mechanism that is independent of neuropilin-1 and heparan sulfate proteoglycans.

35 pecific genes including VEGFR-3, FGFR-3, and neuropilin-1 and is required along with Prox1 to maintai

36 PDC secretion of IFN-alpha and expression of Neuropilin-1 and MHC I.

37 Neuropilin-1 and neuropilin-2 bind differentially to dif

38 Neuropilin-1 and neuropilin-2 show specificity in bindin

39 l repellents that cause repulsion by binding Neuropilin-1 and Neuropilin-2, respectively.

40 Furthermore, the Sema3A receptor proteins, neuropilin-1 and plexin, and the Sema3A signaling molecu

41 1 involves heparan sulfate proteoglycans and neuropilin-1 and results in long-term productive infecti

42 A and Slit2, and their respective receptors, Neuropilin-1 and Robo2.

43 ng of VEGF to low-affinity binding sites and neuropilin-1 and stimulates further growth factor recept

44 also upregulated VEGFR2 and its co-receptor neuropilin-1 and suppressed the expression of semaphorin

45 iven the overlap between processes involving neuropilin-1 and tuftsin, we propose that at least some

46 th factor A (VEGF-A) isoforms, expression of neuropilin-1 and VEGF receptor 1 in tumors or plasma, an

47 The arterial marker neuropilin-1 and venous marker EphB4 are ectopically exp

48 this study, we produced a variety of mutant neuropilin-1s and tested their cell adhesion activity.

49 The neuropilins-1 and -2 (NRP1 and NRP2) function as recepto

50 iple combination of selection markers--CD34, neuropilin 1, and human kinase insert domain-containing

51 ication of sialoglycoproteins such as CD105, neuropilin-1, and CLEC14A, which have already been descr

52 (VEGF) and three of its receptors, VEGFR-2, neuropilin-1, and neuropilin-2, in paraffin-embedded sam

53 affected in predicted ways by antibodies to neuropilin-1, and that neuropilin-1 and -2 can form homo

54 omologous to the extracellular CUB domain of neuropilin-1, and the C-terminal region consists of a gr

55 ate the role of a potential guidance factor, neuropilin-1, and use functional knockdown assays, tissu

56 mplex of chondroitin C sulfate proteoglycan, neuropilin-1, and VEGF receptor-2, overexpressed togethe

57 wth factor-A (VEGF-A), protein expression of neuropilin-1, and VEGF receptors-1 and -2 (VEGFR-1 and V

58 Moreover, mice treated with anti-neuropilin-1 antibodies exhibited a significant decrease

59 IV repulsive response, and these domains of neuropilin-1 are necessary and sufficient for binding of

60 In conclusion, flt-1, KDR, and neuropilin-1 are present on cultured HMC, and VEGF(165)

61 Plasma VEGF-A and tumor neuropilin-1 are strong biomarker candidates for predict

62 merulus, and VEGF receptors (flt-1, KDR, and neuropilin-1) are present on endothelial cells and other

63 aging, as well as suggest miR-208a, AT2R and neuropilin 1 as potential therapeutic targets and mechan

64 We identified neuropilin-1 as a mediator of cancer cell invasion by a

65 of TKPPR had greatly increased affinity for neuropilin-1 based on competition binding experiments.

66 Investigation of PlGF/Neuropilin-1 binding and function suggests a critical ro

67 Third, in endothelial cells, neuropilin-1 binds a potent endothelial cell mitogen, va

68 Second, in neuronal cells, neuropilin-1 binds the class 3 semaphorins, which are ne

69 invasion in vitro and that the VEGF receptor Neuropilin-1 but not Flt-1 is essential for this functio

70 expressed the mRNA for VEGF receptor (VEGFR) neuropilin-1 but not the VEGFRs Flt-1 or KDR.

71 t HN33 cells expressed VEGFR-2 receptors and neuropilin-1, but not VEGFR-1 receptors.

72 he generation of a dominant negative form of neuropilin-1 by the deletion of one of its extracellular

73 Lastly, neuropilin-1 can homomultimerize and form heteromultimer

74 The model predicts that Neuropilin-1 can induce differences in the surface-to-in

75 express similar levels of Sema3A receptors (neuropilin-1, cell adhesion molecule L1, and plexinA4),

76 nd tLyP-1 internalize into cells through the neuropilin-1-dependent CendR internalization pathway.

77 tissue permeability in a tumor-specific and neuropilin-1-dependent manner, allowing coadministered d

78 ema3A decreases cell-substrate adhesion in a neuropilin-1-dependent manner.

79 When coexpressed in cells with KDR, neuropilin-1 enhances the binding of VEGF165 to KDR and

80 th, portal vessels undergo a transition from Neuropilin-1(+)Ephrin-B2(+) artery to EphB4(+) vein phen

81 CI, 0.59 to 0.97) versus patients with high neuropilin-1 expression (HR, 1.07; 95% CI, 0.81 to 1.40;

82 Neuropilin-1 expression in anergic conventional CD4(+) T

83 Although neuropilin-1 expression in GBMs was previously shown, it

84 Baseline plasma VEGF-A levels and tumor neuropilin-1 expression were identified as potential pre

85 Though the binding sites in neuropilin-1 for the class 3 semaphorins and VEGF(165) h

86 When neuropilin-1 function is knocked down in ovo, neural cre

87 Interestingly, with the reduction of neuropilin-1 function, neural crest cells still form seg

88 tract region that are attenuated by blocking neuropilin-1 function.

89 ls of multiple genes and proteins (including Neuropilin 1, glucocorticoid-induced tumor necrosis fact

90 crease in the pTreg to CD4(+)CD25(+)Foxp3(+) neuropilin-1(high) thymic Treg ratio by day 10.

91 study highlights the proangiogenic receptor neuropilin 1 in macrophages and microglial cells in glio

92 A novel role for myeloid cell-specific neuropilin 1 in mitigating sepsis.

93 the translation of the guidance cue receptor Neuropilin-1 in RGCs, with Hermes knock-down resulting i

94 er, that sensory neurons are able to express neuropilin-1 in the absence of Brn3a.

95 hosphorylation status and down-regulation of neuropilin-1 in the HemSCs demonstrate that VEGFR-2 and

96 and in vivo evidence for a critical role of neuropilin-1 in wound angiogenesis.

97 giogenic receptors (alphavbeta3 integrin and neuropilin-1) in vitro as well as in vivo.

98 e transfer experiments and the expression of neuropilin-1 indicate that these cells are predominantly

99 rent iNKT subsets defined by CD4, NK1.1, and neuropilin-1, indicating that distinct functional subpop

100 Conversely, inhibition of VEGF165 binding to neuropilin-1 inhibits its binding to KDR and its mitogen

101 s a critical role for heparin-binding domain/Neuropilin-1 interaction and its regulation by plasmin p

102 These results suggest that neuropilin-1 is a necessary component of receptor comple

103 We propose that neuropilin-1 is a novel VEGF receptor that modulates VEG

104 Neuropilin-1 is a receptor for Sema III.

105 Neuropilin-1 is a receptor for semaphorin3A (Sema3A), a

106 Neuropilin-1 is a type 1 membrane protein with three dis

107 The cAMP-dependent guidance receptor neuropilin-1 is also lost from beta3GnT2(-/-) OSNs and a

108 Neuropilin-1 is expected to form complexes with the plex

109 irement for these two Plexins: signaling via Neuropilin-1 is mediated principally by Plexin-A4, where

110 surprise, we found that membrane-associated neuropilin-1 is polysialylated at approximately 50% of t

111 vation and RNA interference , we showed that neuropilin-1 is required for GBM cell migration.

112 Sema3A, a ligand for neuropilin-1, is effective in repelling geniculate and t

113 rain regions and a receptor for collapsin-1, neuropilin-1, is expressed by migrating crest cells deri

114 a recently identified co-receptor for VEGF, neuropilin-1, is not well understood.

115 The neuropilin-1 ligand placenta growth factor-2 failed to r

116 ound was driven by the CD4(+)CD25(+)Foxp3(+) neuropilin-1(low) peripheral Treg (pTreg), resulting in

117 An alternate VEGFR, VEGFR-1 or neuropilin-1, may modulate adhesion of leukocytes to tum

118 istic insights into the regulation of PlGF-2/Neuropilin-1-mediated tissue vascularization and growth.

119 blastic cells (MC3T3-E1) expressed Flt-1 and neuropilin-1 mRNA but not KDR.

120 actor (VEGF), VEGF receptors, semaphorin 3F, neuropilin 1, neuropilin 2, podoplanin, and LYVE-1 by qu

121 evels of known A10 elevated genes, including neuropilin 1, neuropilin 2, slit2 and adenylyl cyclase-a

122 ctor to its heterodimeric receptor--Flk1 and neuropilin 1 (NP-1; also called Nrp1)--activates the Not

123 Neuropilin-1 (NP-1) has been identified as a necessary c

124 Neuropilin-1 (NP-1) is a component of the receptor for s

125 Further, we show that neuropilin-1 (NP-1) mediates both PS-dependent and PS-in

126 Neuropilin-1 (NP-1) was first identified as a semaphorin

127 Neuropilin-1 (Np-1), a receptor for semaphorin 3A and va

128 orin-binding proteins, plexin 1 (Plex 1) and neuropilin-1 (NP-1), form a stable complex.

129 t and are linked to tumor cell expression of neuropilin-1 (Np-1).

130 Semaphorin 3A (Sema3A) binds to neuropilin-1 (NP1) and activates the transmembrane Plexi

131 Neuropilin-1 (NP1), in conjunction with plexins, promote

132 Neuropilin-1 (Npn-1) is a cell surface receptor that bin

133 Neuropilin-1 (Npn-1) is a receptor for both semaphorin 3

134 Neuropilin-1 (Npn-1) is a receptor that binds multiple l

135 Interestingly, neuropilin-1 (Npn-1) is expressed by periocular neural c

136 escribed VEGF(165) isoform-specific receptor neuropilin-1 (Npn-1) is responsible for the difference i

137 Neuropilin-1 (Npn-1), a receptor for semaphorin III, med

138 otein that has chemorepulsive properties for neuropilin-1 (npn-1)- expressing axons.

139 ding of Sema3A to its high-affinity receptor Neuropilin-1 (Npn-1).

140 ble semaphorin D (semD) binds to growth cone neuropilin-1 (Npn-1).

141 L1) and the semaphorin 3A (Sema3A) receptor, neuropilin 1 (Npn1), important for establishment of area

142 ssed in the lens epithelium and its receptor Neuropilin-1 (Npn1) is expressed in the trigeminal gangl

143 We provide evidence that Neuropilin 1 (Nrp-1), highly expressed by Foxp3(+) T reg

144 RPPR peptide, with affinity for the receptor neuropilin-1 (NRP), which is expressed on both endotheli

145 that must be C-terminally exposed to trigger neuropilin-1 (NRP-1) binding, cellular internalization a

146 Instead, VEGF-A acts via the neuropilin-1 (NRP-1) co-receptor.

147 eport that expression of the VEGF coreceptor neuropilin-1 (NRP-1) coincides with expression of Brachy

148 An increased staining of neuropilin-1 (NRP-1) further showed a transformation cha

149 Neuropilin-1 (NRP-1) has been found to be expressed by e

150 Expression of neuropilin-1 (NRP-1) has been shown in many cancer cells

151 tosis transport pathway that is regulated by neuropilin-1 (NRP-1) has recently been reported.

152 Heparin/heparan sulfate proteoglycans and neuropilin-1 (NRP-1) have been identified as co-receptor

153 gated the role of semaphorin 3A (Sema3A) and neuropilin-1 (Nrp-1) in lymphatic vessel maturation and

154 Neuropilin-1 (NRP-1) is a type 1 membrane protein that b

155 that trafficking of the angiogenic receptor neuropilin-1 (NRP-1) is abrogated by the liver kinase B1

156 raphy showed that the CendR peptides bind to neuropilin-1 (NRP-1) on the target cells.

157 essing a conditional deletion of endothelial neuropilin-1 (Nrp-1) or in wild-type mice systemically t

158 Here, we report that neuropilin-1 (NRP-1) orchestrates communications between

159 One targets the neuropilin-1 (NRP-1) receptors of cancer cells through t

160 xpression of VEGF and VEGF receptors KDR and neuropilin-1 (NRP-1) was detected in these cells.

161 Neuropilin-1 (NRP-1) was first described as a coreceptor

162 Recently, neuropilin-1 (NRP-1) was reported to bind and activate t

163 liver fibrosis, the axonal guidance molecule neuropilin-1 (NRP-1) was upregulated in activated HSCs,

164 , heparan sulfate proteoglycans (HSPGs), and neuropilin-1 (NRP-1) were demonstrated to facilitate HTL

165 and conditional knockout mice, we show that neuropilin-1 (NRP-1), a known receptor of VEGF, is neces

166 As a model, we have targeted neuropilin-1 (NRP-1), a membrane-bound receptor expresse

167 Neuropilin-1 (NRP-1), a recently identified co-receptor

168 we demonstrate that a cell surface molecule, neuropilin-1 (Nrp-1), is expressed at high levels on nT

169 vation of both VEGF receptor 2 (VEGFR-2) and neuropilin-1 (Nrp-1), since neutralizing antibodies to e

170 th heparan sulfate proteoglycans (HSPGs) and neuropilin-1 (NRP-1), two molecules important for HTLV-1

171 s mediated through a molecular cross-talk of neuropilin-1 (NRP-1), VEGFR1 (Flt-1), and phosphoinositi

172 We found that Neuropilin-1 (Nrp-1), which is expressed by most Treg ce

173 We identify Neuropilin-1 (NRP-1)-mediated activation of KDR signalin

174 g receptor as the transmembrane glycoprotein neuropilin-1 (NRP-1).

175 actions with alphavbeta3/beta5 integrins and neuropilin-1 (NRP-1).

176 n exposed site within the b1 domain of human neuropilin-1 (NRP-1).

177 progression by binding with its co-receptor, neuropilin-1 (NRP-1).

178 emma vesicle-associated protein-1 (PV-1) and neuropilin-1 (NRP-1).

179 h through interaction with the VEGF receptor neuropilin-1 (NRP-1).

180 Here we show that Neuropilin 1 (Nrp1) and Nrp2, transmembrane proteins wit

181 BMA nucleus, owing to reduced expression of neuropilin 1 (Nrp1) and Nrp2, two semaphorin receptors t

182 VEGF165 binds the transmembrane protein neuropilin 1 (NRP1) and promotes the migration, survival

183 mall molecule ligand for the VEGF-A receptor neuropilin 1 (NRP1) and the structural characterization

184 demonstrate that beta8 integrin (Itgb8) and neuropilin 1 (Nrp1) cooperatively promote CNS angiogenes

185 Moreover, high expression of PlGF receptor neuropilin 1 (Nrp1) correlates with poor overall surviva

186 Here we show that neuropilin 1 (NRP1) directly interacts with EBV gB(23-43

187 tion, bevacizumab decreased Ang1 and induced neuropilin 1 (NRP1) expression in tumor-associated macro

188 semaphorin SEMA3C, and their shared receptor neuropilin 1 (NRP1) in OFT development, the precise mech

189 Neuropilin 1 (NRP1) is a receptor for class 3 semaphorin

190 Neuropilin 1 (NRP1) is a transmembrane glycoprotein that

191 We report here that Neuropilin 1 (Nrp1) is expressed at high levels by most

192 Neuropilin 1 (NRP1) plays an important but ill-defined r

193 analyses with in vitro assays, we show that neuropilin 1 (NRP1) promotes contralateral RGC projectio

194 of GlyRS, enabling GlyRS(CMT2D) to bind the neuropilin 1 (Nrp1) receptor.

195 by endothelial cells where it partners with neuropilin 1 (Nrp1) to form a functional receptor for th

196 The transmembrane receptor protein neuropilin 1 (Nrp1) was recently identified as an aberra

197 Neuropilin 1 (Nrp1), a coreceptor for class 3 semaphorin

198 Moreover, TAOK2 interacts with Neuropilin 1 (Nrp1), a receptor protein that binds the s

199 Emerging evidence suggests that neuropilin 1 (Nrp1), an originally defined coreceptor fo

200 ssel growth, endothelial cells (ECs) express neuropilin 1 (NRP1), and NRP1 associates with the recept

201 f these targets is the guidance cue receptor Neuropilin 1 (Nrp1), which is sensitive to the repellent

202 However, the addition of neuropilin 1 (Nrp1)-blocking antibody or siRNA knockdown

203 e identified the LD22-4 membrane receptor as neuropilin 1 (NRP1).

204 Neuropilin-1 (NRP1) and neuropilin-2 (NRP2) are both rec

205 Neuropilin-1 (NRP1) and NRP2 are cell surface receptors

206 ein binds to lymphatic valves expressing the Neuropilin-1 (Nrp1) and PlexinA1 receptors.

207 VEGF receptors VEGFR1, VEGFR2 and Neuropilin-1 (NRP1) are mostly in 'Free State'.

208 ass spectrometry-based approach, we identify neuropilin-1 (NRP1) as a NE receptor that mediates uptak

209 n part, on signaling through the VEGF-VEGFR2-Neuropilin-1 (NRP1) axis.

210 In endothelial cells, neuropilin-1 (NRP1) binds vascular endothelial growth fa

211 Neuropilin-1 (NRP1) functions as a coreceptor through in

212 Neuropilin-1 (Nrp1) guides the development of the nervou

213 has implicated the transmembrane co-receptor neuropilin-1 (NRP1) in cancer progression.

214 Sema4a) and the Treg-cell-expressed receptor neuropilin-1 (Nrp1) interact both in vitro, to potentiat

215 Neuropilin-1 (NRP1) is a 130-kDa transmembrane receptor

216 Neuropilin-1 (Nrp1) is a cell surface molecule originall

217 Neuropilin-1 (NRP1) is a cell-surface receptor for both

218 Neuropilin-1 (NRP1) is a coreceptor for multiple extrace

219 Neuropilin-1 (NRP1) is a coreceptor to a tyrosine kinase

220 Neuropilin-1 (NRP1) is a receptor for two unrelated liga

221 Neuropilin-1 (NRP1) is a VEGF(165) and semaphorin recept

222 Neuropilin-1 (Nrp1) is an essential receptor for angioge

223 Neuropilin-1 (NRP1) is expressed by endothelial cells an

224 Neuropilin-1 (Nrp1) is required to maintain intratumoral

225 tion of circulating monocytes expressing the neuropilin-1 (Nrp1) receptor (Nrp1-expressing monocytes;

226 onset of Sema3A sensitivity and concomitant neuropilin-1 (NRP1) receptor expression and caused cell-

227 Neuropilin-1 (NRP1) was first described as a receptor fo

228 Neuropilin-1 (NRP1), a cell-surface receptor for both va

229 Neuropilin-1 (NRP1), a non-tyrosine kinase receptor, is

230 ligo G) reduce endothelial levels of surface neuropilin-1 (NRP1), a receptor shared by semaphorin 3A

231 Here, we demonstrate that neuropilin-1 (NRP1), a Semaphorin receptor expressed in

232 disrupts the developmental downregulation of Neuropilin-1 (Nrp1), the receptor for Sema3A, in sensory

233 Neuropilin-1 (NRP1), which is a critical receptor implic

234 Mice that lack the transmembrane receptor neuropilin-1 (Nrp1), which modulates GAM immune polariza

235 e show this is a key endothelial function of neuropilin-1 (Nrp1), which suppresses the stalk-cell phe

236 Semaphorin3A (Sema3A) which both signal via neuropilin-1 (Nrp1).

237 dritic cell (pDC) marker, BDCA4, identifying neuropilin-1 (NRP1); and the helper T cell marker, CD4.

238 microenvironment by increasing the levels of neuropilin-1 (NRP1, a co-receptor of vascular endothelia

239 Sema III signal is mediated predominantly by neuropilin-1 oligomers, the Sema IV signal by neuropilin

240 Importantly, deletion of either neuropilin 1 or plexin A3 significantly reduces developm

241 Sema K1 does not bind to neuropilin-1 or neuropilin-2, the two receptors implicat

242 that VEGF immobilization, interactions with Neuropilin-1, perturbations of VEGFR2 trafficking, and c

243 esults support that Farp1 interacts with the Neuropilin-1/PlexinA1 complex and colocalizes with Plexi

244 that SEMA3A acts as a potent attractant for neuropilin-1-positive (NRP-1-positive) MPs.

245 pment and is not required for maintenance of neuropilin-1-positive natural Tregs in the periphery, it

246 MAOA-dependent activation of neuropilin-1 promoted AKT/FOXO1/TWIST1 signaling, allowi

247 hat lung cancers (n = 34) always express the neuropilin-1 receptor for secreted semaphorins, whereas

248 neurons transduce this signal by way of the neuropilin-1 receptor.

249 owed slightly decreased binding to the NRP1 (neuropilin-1) receptor, and analyses suggested the hepar

250 stemmed from a failure to expand functional neuropilin-1(+) regulatory T (T reg) cells in the absenc

251 L1 and modulating the endocytosis of the L1/neuropilin 1 Sema3A receptor complex.

252 e adhesion and suggest that targeting Sema3A-neuropilin-1 signaling may limit GBM infiltration.

253 ar tumor areas is regulated by Semaphorin 3A/Neuropilin-1 signaling; interference with this pathway e

254 Specific inhibition of neuropilin-1 significantly reduced CNS vascular permeabi

255 Time-lapse imaging shows that neuropilin-1 siRNA transfected neural crest cells stop a

256 betic female rats have reduced expression of neuropilin 1 that attenuates cardiomyopathy compared to

257 hat the misexpression of a dominant-negative neuropilin-1 that blocks SEMA-3A-mediated signaling in o

258 A truncated form of neuropilin-1 that is missing its cytoplasmic domain fail

259 dipocytes, probably through up-regulation of neuropilin-1, the OB-mediated enhanced hematopoiesis fun

260 Specifically, pDCs upregulate neuropilin-1 to enable the long term interactions of pDC

261 for by exon 8 may stabilize VEGF binding to neuropilin-1 to facilitate signaling through VEGFR-2.

262 implicate Sema3A as an autocrine signal for neuropilin-1 to promote GBM dispersal by modulating subs

263 h 2 (ba2), is due to chemoattraction through neuropilin-1-vascular endothelial growth factor (VEGF) i

264 pendent on chemoattractive signaling through neuropilin-1-VEGF interactions.

265 r involved signaling through VEGF receptor 2-neuropilin 1 (VEGFR2-NP1) receptors on endometrial strom

266 model of dermal wound repair, we found that neuropilin-1 was abundantly expressed on new vasculature

267 VEGF-A in endothelial cells, and coreceptor neuropilin-1 was significantly decreased in Dll4-transdu

268 Neuropilin (neuropilin-1) was recently identified as a receptor for

269 dHAND-null hearts), the VEGF(165) receptor, neuropilin-1, was found to be downregulated in dHAND mut

270 onstrated that the cell adhesion ligands for neuropilin-1 were proteins and distributed in embryonic

271 domains within the extracellular segment of neuropilin-1 were required for the cell adhesion activit

272 Unlike neuropilin-1, which binds with high affinity to the thre