ライフサイエンスコーパス: neurosurgical

1 Adult neurologic and neurosurgical 1,118 patients in the pre period, 731 pati

2 wo groups: endovascular 83% (626 of 755) and neurosurgical 82% (584 of 713).

3 ive-compulsive disorder (OCD) have undergone neurosurgical ablation for more than half a century.

4 of neuroleptics, deep-brain stimulation, and neurosurgical ablation for treatment-resistant OCD.

5 uld have access to the potential benefits of neurosurgical advances.

6 ic validation cohort comprised patients from neurosurgical and intensive care centers in Edinburgh an

7 itrous oxide as a component of anesthesia in neurosurgical and neurologically at-risk patients.

8 ntraoperative navigation during a variety of neurosurgical and other types of surgical procedures.

9 AVMs is an efficient and safe alternative to neurosurgical and radiosurgical methods.

10 Innovations in neurosurgical and radiotherapeutic techniques have resul

11 terviewees were from open medical, surgical, neurosurgical, and cardiovascular ICUs.

12 eep brain stimulation (DBS) is a widely used neurosurgical approach to treating tremor and other move

13 Neurosurgical approaches are available such as capsuloto

14 roposed as a noninvasive alternative to open neurosurgical approaches to manage a variety of conditio

15 t will be needed to determine whether a sham neurosurgical arm should be included in clinical trials

16 The inclusion of a sham neurosurgical arm will be guided in part by the objectiv

17 age, 45 +/- 15 y) who had been referred for neurosurgical assessment of unclear brain lesions and ha

18 luding blood-brain barrier (BBB) disruption, neurosurgical-based approaches, and molecular design.

19 ng and peritumoral nonenhancing stereotactic neurosurgical biopsy samples from treatment-naive GBMs w

20 for preoperative language lateralization in neurosurgical candidates.

21 head injury, and to establish the effect of neurosurgical care on mortality after severe head injury

22 nd committed to, operative and postoperative neurosurgical care.

23 chest tubes, diagnostics, and orthopedic and neurosurgical care; mean ratings </= 2).

24 Fifty-four neurosurgical centers in North America.

25 t guidelines, suggesting that treatment in a neurosurgical centre represents an important strategy in

26 nts with severe head injury are treated in a neurosurgical centre.

27 hose treated in a neurosurgical versus a non-neurosurgical centre.

28 case mix compared with patients treated at a neurosurgical centre.

29 ms were enrolled between 1994 and 2002 at 43 neurosurgical centres and randomly assigned to clipping

30 We followed up 1644 patients in 22 UK neurosurgical centres for death and clinical outcomes fo

31 ting less than 96 h from ictus from 35 acute neurosurgical centres in nine countries.

32 At 13 neurosurgical centres in the UK, between November, 2000,

33 racranial aneurysms, who were admitted to 42 neurosurgical centres, mainly in the UK and Europe, took

34 ween 1996 and 2003) were treated only in non-neurosurgical centres; such treatment was associated wit

35 They were randomly assigned to neurosurgical clipping (n=1070) or endovascular coiling

36 nial aneurysms and randomly assigned them to neurosurgical clipping (n=1070) or endovascular treatmen

37 aneurysm, for which endovascular coiling and neurosurgical clipping are therapeutic options, the outc

38 ficacy of endovascular coiling with standard neurosurgical clipping for such aneurysms judged to be s

39 , patients were randomly allocated to either neurosurgical clipping or endovascular coiling after a s

40 a ruptured intracranial aneurysm with either neurosurgical clipping or endovascular coiling.

41 ling and 657 (79%) of 835 patients allocated neurosurgical clipping were alive (odds ratio [OR] 1.35,

42 coiling and 370 (78%) patients treated with neurosurgical clipping were independent (modified Rankin

43 likely after endovascular coiling than after neurosurgical clipping, but the risk was small and the p

44 common after endovascular coiling than after neurosurgical clipping.

45 esult in independent survival at 1 year than neurosurgical clipping; the survival benefit continues f

46 significant reduction (19.0%) in the rate of neurosurgical consultation (post-BIG group, 273 patients

47 s the management of TBI without the need for neurosurgical consultation and unnecessary imaging.

48 e of corticosteroids, if possible, and early neurosurgical consultation for stereotactic biopsy.

49 equiring prompt anticoagulation reversal and neurosurgical consultation.

50 Proportion of patients who received neurosurgical consultations (P < 0.001) and repeat head

51 repeated computed tomography of the head and neurosurgical consultations.

52 iety of tumors, and trained dozens of future neurosurgical department heads.

53 established and patient was referred to the Neurosurgical Department.

54 DESIGN, SETTING, AND PATIENTS: Both neurosurgical departments are exclusive providers in adj

55 ntact depth electrodes implanted in HG of 14 neurosurgical epilepsy patients as they vocalized vowel

56 Using recordings from neurosurgical epilepsy patients with intracranially impl

57 5% CI 5.7 to 7.5) per 100 person-years after neurosurgical excision (median follow-up 3.3 years) and

58 g cerebral cavernous malformations (CCMs) by neurosurgical excision or stereotactic radiosurgery are

59 sks of CCM treatment (and the lower risks of neurosurgical excision over time, from recently bled CCM

60 After neurosurgical excision the incidence of the composite ou

61 intervention (any endovascular embolization, neurosurgical excision, or stereotactic radiosurgery alo

62 to available medication and may benefit from neurosurgical excisional surgery.

63 reater in the endovascular group than in the neurosurgical group at 10 years.

64 and 14% (144 of 1041) of the patients in the neurosurgical group had died (log-rank p=0.03).

65 dependency was significantly greater in the neurosurgical group than in the endovascular group.

66 cal procedures (general surgery, orthopedic, neurosurgical, gynecologic, and urologic) in adult patie

67 Patients admitted to the neurological or neurosurgical ICU are likely to have palliative care nee

68 btained during their admission to the trauma/neurosurgical ICU of Presbyterian University Hospital fr

69 Patients were managed in specialized neurosurgical ICUs in 66% of centers and in general ICUs

70 nd were enrolled within 6 hours of injury at neurosurgical intensive care units in 2 US level I traum

71 history in the cardiac, cardiothoracic, and neurosurgical intensive care units.

72 None of the 2,823 low-risk patients required neurosurgical intervention (negative predictive value [N

73 re-BIG group, 59 patients [14.2%]; P = .14), neurosurgical intervention (post-BIG group, 61 patients

74 risk status to 420 of 420 patients requiring neurosurgical intervention (sensitivity, 100.0% [95% con

75 2,823 of 11,350 patients who did not require neurosurgical intervention (specificity, 24.9% [95% CI:

76 istently in detecting MMTBI, CT lesions, and neurosurgical intervention across 7 days.

77 ing "high-risk" status to patients requiring neurosurgical intervention among a cohort of 11,770 blun

78 including 111 patients (1.43%) who required neurosurgical intervention and 306 (3.94%) who had signi

79 cal care coupled with timely and appropriate neurosurgical intervention can produce significant impro

80 The balance of risk and benefit from early neurosurgical intervention for conscious patients with s

81 Neurosurgical intervention for subdural hematoma decreas

82 In recent years, the safety and efficacy of neurosurgical intervention has rapidly improved for brai

83 In our study, the Canadian criteria for neurosurgical intervention identified 108 of 111 patient

84 16 (80%) had positive CT scans, which led to neurosurgical intervention in nine (45%).

85 scan and defined by the subsequent need for neurosurgical intervention in the population fully satis

86 vere traumatic brain injury (TBI) in need of neurosurgical intervention is complicated in a situation

87 No patient required neurosurgical intervention of their anterior temporal ED

88 : Proportion of patients with TBI in need of neurosurgical intervention per GCS score or Simplified M

89 Neurosurgical intervention remains the first step in eff

90 s of drug-resistant epilepsy, often requires neurosurgical intervention targeting seizure foci, such

91 ion identified 108 of 111 patients requiring neurosurgical intervention to yield a sensitivity of 97.

92 ce of injuries leading to death or requiring neurosurgical intervention was 0.9% (95% CI, 0.78%-1.0%)

93 Acute neurosurgical intervention was rare (3 of 86 total cases

94 with severe TBI and severe TBI in need of a neurosurgical intervention were similar in patients pres

95 dback, which can be helpful in all stages of neurosurgical intervention without affecting the duratio

96 ial pressure monitoring, vasopressors, acute neurosurgical intervention, and extracranial operation.

97 creening of intracranial injuries in need of neurosurgical intervention, but may also provide informa

98 hage on repeated computed tomographic scans, neurosurgical intervention, hospital admission, intensiv

99 The primary outcome was the composite of neurosurgical intervention, intubation for more than 24

100 r distinguishing patients with and without a neurosurgical intervention, the range for GFAP was 0.91

101 ohort, identified all 111 patients requiring neurosurgical intervention, yielding a sensitivity of 10

102 nt that the patient may no longer be fit for neurosurgical intervention.

103 re reveals important opportunities for early neurosurgical intervention.

104 y outcome, including 8.3% (n = 70) who had a neurosurgical intervention.

105 ic intracranial lesions on head CT scan, and neurosurgical intervention.

106 entify patients with severe TBI in need of a neurosurgical intervention.

107 identify patients with severe TBI in need of neurosurgical intervention.

108 Despite referral bias, services offering neurosurgical interventions and health service planning

109 Neurosurgical interventions can be effective therapeutic

110 heir ability to identify patients in need of neurosurgical interventions, no difference was found bet

111 mal in psychiatric disorders and affected by neurosurgical interventions, such as deep brain stimulat

112 h respect to the safety and effectiveness of neurosurgical interventions.

113 h subcortical nuclei have been the target of neurosurgical lesions as well as deep brain stimulation

114 y to reappear a quarter century later in the neurosurgical literature.

115 Neurosurgical navigation methods are beneficial in provi

116 his review focuses on recent developments in neurosurgical navigational techniques that enable real-t

117 ermine the effectiveness of this approach in neurosurgical (NSY) patients, we conducted a randomized

118 egies that are essential for next-generation neurosurgical oncologists and major brain tumor centers.

119 ients (30%) with GCS scores of 3 to 14 had a neurosurgical operation (P < .001).

120 1%) with a GCS score of 15 were in need of a neurosurgical operation, and fewer than 51 of the 171 pa

121 the electrocorticogram recorded during awake neurosurgical operations in Broca's area and in the domi

122 urgical specialties: general, gynecological, neurosurgical, oral, orthopedics, otolaryngologic, plast

123 general, vascular, thoracic, genitourinary, neurosurgical, orthopedic, or spine surgery from October

124 ollection of reference images for label-free neurosurgical pathology.

125 usion-related morbidity and mortality in the neurosurgical patient are limited.

126 Perioperative transfusion thresholds in the neurosurgical patient are undefined.

127 y from prefrontal depth electrodes in a rare neurosurgical patient while he performed the Iowa Gambli

128 nt understanding of blood transfusion in the neurosurgical patient, as well as other blood component

129 e intraoperative management of the pediatric neurosurgical patient.

130 n the anesthetic management of the pediatric neurosurgical patient.

131 were at greater risk of infection than other neurosurgical patients (3/14 vs. 0/566; P<.001).

132 works of the human brain, we recruited seven neurosurgical patients (four males and three females) wh

133 on of intensive care unit management for all neurosurgical patients after brain tumor resection are n

134 om 489 single neurons in the amygdalae of 41 neurosurgical patients and found a categorical selectivi

135 e, we administered a free recall test to 114 neurosurgical patients and used intracranial theta and h

136 onses from 630 parahippocampal neurons in 24 neurosurgical patients during visual stimulus presentati

137 tral neural activity, based on data from 294 neurosurgical patients fitted with indwelling electrodes

138 ive versus liberal transfusion strategies in neurosurgical patients has been controversial.

139 in the human hippocampus and amygdala while neurosurgical patients made memory retrieval decisions t

140 As thirteen neurosurgical patients performed a person recognition ta

141 Neurosurgical patients performed this task as we recorde

142 espread cortical and subcortical sites as 20 neurosurgical patients performed working memory tasks.

143 d single-neuron activities and LFPs in human neurosurgical patients performing a face/nonface categor

144 Recording neuronal activity from neurosurgical patients performing a virtual-navigation t

145 ed recordings of single-neuron activity from neurosurgical patients playing a virtual-navigation vide

146 ocorticographic recordings taken as 46 human neurosurgical patients studied and freely recalled lists

147 electrocorticographic recordings taken as 69 neurosurgical patients studied and recalled lists of wor

148 ocorticographic recordings taken as 68 human neurosurgical patients studied and subsequently recalled

149 e-unit activity in multiple brain regions of neurosurgical patients to better characterize spindle ac

150 , we studied the responses of MTL neurons in neurosurgical patients to known concepts (people and pla

151 overage of iEEG recordings in 12 eye-tracked neurosurgical patients to test whether a similar stabili

152 We recorded the activity of MTL neurons in neurosurgical patients while they learned new associatio

153 analyzed intracranial brain recordings from neurosurgical patients while they studied lists of visua

154 gle neurons within the amygdalae of two rare neurosurgical patients with ASD.

155 In this study, we used fMRI in five neurosurgical patients with focal vmPFC lesions to test

156 l gap through a novel application of fMRI in neurosurgical patients with focal, bilateral ventromedia

157 unctional magnetic resonance imaging in four neurosurgical patients with focal, bilateral vmPFC damag

158 ver 200 single neurons in the amygdalae of 7 neurosurgical patients with implanted depth electrodes.

159 Neurosurgical patients with implanted electrodes perform

160 Neurosurgical patients with pericardial tissue implants

161 m provides stable neuromuscular blockade for neurosurgical patients with traumatic brain injury.

162 Anemia is common in neurosurgical patients, and is associated with secondary

163 is a potentially devastating complication in neurosurgical patients, and plasma fibrinogen concentrat

164 rature of distinct cortical regions in awake neurosurgical patients, and we relate this perturbation

165 In critically ill neurologic and neurosurgical patients, elevated body temperature is com

166 te early bacterial meningitis development in neurosurgical patients, enabling earlier diagnostic cert

167 Recording from 20 neurosurgical patients, we directly examined the relatio

168 ing from over 200 neurons in the amygdala of neurosurgical patients, we found robust encoding of the

169 Using direct cortical surface recordings in neurosurgical patients, we studied the evolution of acti

170 en and how aggressively to transfuse RBCs in neurosurgical patients.

171 hy adults, and single-neuron recordings in 9 neurosurgical patients.

172 idence to guide RBC transfusion practices in neurosurgical patients.

173 that highlight issues in RBC transfusion in neurosurgical patients.

174 and unit firing in multiple brain regions of neurosurgical patients.

175 t the dogmatic avoidance of nitrous oxide in neurosurgical patients.

176 wn to be a predictor of poor outcome in many neurosurgical patients.

177 nctional MRI in the preoperative planning of neurosurgical patients.

178 ter their procedures, such as orthopedic and neurosurgical patients.

179 irectly using multielectrode recordings from neurosurgical patients.

180 s of aseptic and bacterial meningitis within neurosurgical patients.

181 ntracranial hemorrhage, play a vital role in neurosurgical planning or can be misidentified as seriou

182 uate it in 3D on 60 brain tumor datasets for neurosurgical planning purposes.

183 te portrayals of growing skull fractures for neurosurgical planning, but its routine use for imaging

184 egarding the use of this drug in the general neurosurgical population.

185 r the abscess was identified after a primary neurosurgical procedure (n = 43) or was a spontaneous ab

186 re, two patients did not have a history of a neurosurgical procedure and had community-acquired anaer

187 DBS is an increasingly common neurosurgical procedure that has been successfully used

188 entricular drain (EVD) insertion is a common neurosurgical procedure.

189 ime of cerebral circulation intervention for neurosurgical procedure.

190 The patient underwent an emergency neurosurgical procedure.

191 Many neurosurgical procedures are associated with significant

192 onsiderations for thoracic and thoracoscopic neurosurgical procedures are considered, emphasizing the

193 oaches in the context of patients undergoing neurosurgical procedures for medical treatment.

194 Data collected during awake neurosurgical procedures for the treatment of epilepsy p

195 e-neuronal activity in human subjects during neurosurgical procedures involving microelectrode record

196 emaining refractory to 'standard' therapies, neurosurgical procedures may be considered.

197 hat neuroimaging findings, stratification by neurosurgical procedures performed, and genomic informat

198 tive transfusion management for intracranial neurosurgical procedures presents the clinician with mul

199 cialized nature of these and other pediatric neurosurgical procedures prompt calls for similarly trai

200 ovel therapeutics as well as optimization of neurosurgical procedures to remove the tumor tissue are

201 Ocular complications of several neurosurgical procedures were also reported during this

202 Clinical events including neurosurgical procedures were identified using validated

203 uently associated with neurological disease, neurosurgical procedures, and use of psychoactive drugs.

204 ly used for a variety of adult and pediatric neurosurgical procedures, but also its use has expanded

205 ctors and in patients admitted from home for neurosurgical procedures, routine admission surveillance

206 ch, and electrocauterization when performing neurosurgical procedures, which is termed as surgical br

207 nts undergoing craniotomies for a variety of neurosurgical procedures.

208 rain injury (SBI) is unavoidable during many neurosurgical procedures.

209 e in the anesthetic management of functional neurosurgical procedures.

210 e imaging is steadily gaining acceptance for neurosurgical procedures.

211 acological intervention, and orthopaedic and neurosurgical procedures.

212 rapy offers the potential to augment current neurosurgical, radiation and drug treatments with little

213 8%) were deemed capable of consenting to the neurosurgical RCT by all 5 psychiatrists.

214 those deemed incapable of consenting to the neurosurgical RCT were found capable of appointing a res

215 to a drug RCT, and capacity to consent to a neurosurgical RCT.

216 ionnaire was sent to the directors of the 44 neurosurgical referral units identified from the UK Medi

217 Neurosurgical resection and medical therapy with bromocr

218 TMEs), we utilized 5-ALA fluorescence-guided neurosurgical resection and sampling, followed by proteo

219 imens from 31 meningioma patients undergoing neurosurgical resection at Brigham and Women's Hospital

220 erapy, 21 patients received other treatment: neurosurgical resection in seven, conventional chemother

221 quency and may be a potential alternative to neurosurgical resection in some cases, though long-term

222 Neurosurgical resection is the standard treatment for su

223 roperties of GBM result in residual tumor at neurosurgical resection margins, representing the source

224 y be free of seizures during the years after neurosurgical resection of epileptogenic tissue.

225 g lymphocytes (TIL) from patients undergoing neurosurgical resection of glioblastoma multiforme (GBM)

226 g has the potential to significantly improve neurosurgical resection of oncologic lesions through imp

227 of patients surviving this condition without neurosurgical resection of the lesions.

228 For people with refractory focal epilepsy, neurosurgical resection offers the possibility of a life

229 oma guides the decision to pursue definitive neurosurgical resection.

230 e and derived cells from patients undergoing neurosurgical resection.

231 aoperative magnetic resonance imaging in the neurosurgical setting.

232 regarding its prognostic significance in the neurosurgical setting.

233 36% vs 25%, p<0.001) and World Federation of Neurosurgical Societies (WFNS) Grade 4 or 5 (42.6% vs 28

234 dmitted with poor-grade (World Federation of Neurosurgical Societies, 3-5) subarachnoid hemorrhage.

235 ontinental and international psychiatric and neurosurgical societies, joined efforts to further elabo

236 metry will facilitate multisubject atlasing, neurosurgical studies, and multimodality brain mapping a

237 used electrocorticography recordings from 16 neurosurgical subjects implanted with grids of electrode

238 ecording electrocorticographic activity from neurosurgical subjects performing auditory repetition ta

239 This has precipitated a crisis in access to neurosurgical support in many trauma systems, often plac

240 e portions of the CB identified in humans as neurosurgical targets for amelioration of psychiatric di

241 that are likely to be captured at different neurosurgical targets.

242 Only the neurosurgical team was aware of treatment assignments.

243 nd study personnel with the exception of the neurosurgical team were masked to treatment assignment.

244 vent of enhanced neuroimaging and functional neurosurgical techniques, a unique window of opportunity

245 europsychiatric disorders, brain targets and neurosurgical techniques, taking into account cultural a

246 siologic testing is an integral part of many neurosurgical techniques, the need to provide sufficient

247 including medical, neurointerventional, and neurosurgical therapies.

248 Deep brain stimulation is an established neurosurgical therapy for movement disorders including e

249 r compared with 243 of 793 (30.6%) allocated neurosurgical treatment (p=0.0019).

250 subthalamic nucleus (STN) is the most common neurosurgical treatment for Parkinson's disease motor sy

251 Improved neurosurgical treatment has resulted in amblyopia replac

252 Neurosurgical treatment is appealing for selected people

253 Neurosurgical treatment may improve seizures in children

254 lts may represent early steps toward a novel neurosurgical treatment modality for alcohol dependence

255 model widely used to explain the efficacy of neurosurgical treatment of essential tremor, are in cont

256 halamic nucleus (STN) is the main target for neurosurgical treatment of motor signs of Parkinson's di

257 h after allocation to an endovascular versus neurosurgical treatment were 22.6% (95% CI 8.9-34.2) and

258 ears for patients allocated endovascular and neurosurgical treatment, respectively.

259 ment, and 1055 of 1070 patients allocated to neurosurgical treatment.

260 and function were impaired even years after neurosurgical trigeminal damage, suggesting that assessm

261 f patients admitted after a head injury to a neurosurgical unit (n=93).

262 AH admitted to the West of Scotland regional neurosurgical unit 10 years previously.

263 We prospectively identified admissions to a Neurosurgical Unit for head injury, collected demographi

264 61 patients who were admitted to a regional neurosurgical unit were examined.

265 jury to craniotomy and direct admission to a neurosurgical unit were not found to be significant prog

266 adjusted odds ratio, 2.64 [1.14, 6.10]), and neurosurgical units (adjusted odds ratio, 2.96 [1.51, 5.

267 supratentorial intracerebral haemorrhage in neurosurgical units show no overall benefit from early s

268 icentre cohort study of EVD insertions in 21 neurosurgical units was performed over 6 months.

269 hout head injury, and for those treated in a neurosurgical versus a non-neurosurgical centre.