ライフサイエンスコーパス: neurotoxin

1 cury and increase circulating levels of this neurotoxin.

2 s dopaminergic neurons against a PD-inducing neurotoxin.

3 ut seafood can also contain methyl mercury-a neurotoxin.

4 suggest a role of this metabolite as a weak neurotoxin.

5 crease soluble Abeta, likely the proximal AD neurotoxin.

6 used by consuming foods containing botulinum neurotoxin.

7 rmed for Clostridium botulinum and botulinum neurotoxin.

8 e world are exposed to lead, a developmental neurotoxin.

9 an illness caused by types A and B botulinum neurotoxin.

10 ol for discriminative detection of different neurotoxins.

11 roup of nonconventional "three-finger" snake neurotoxins.

12 NTs) form a large class of potent and deadly neurotoxins.

13 regulation of mAChRs by "three-finger" snake neurotoxins.

14 und to develop novel inhibitors of botulinum neurotoxins.

15 in survival in PC-12 cells treated with the neurotoxins.

16 cluding biogenic amines, cationic drugs, and neurotoxins.

17 of different brain cell types in response to neurotoxins.

18 ease, essential for maturing of spider venom neurotoxins.

19 otentially fatal paralytic illness caused by neurotoxins.

20 vant for heterodimerization of a subgroup of neurotoxins.

21 opening, as the target for these amphipathic neurotoxins.

22 inium (MPP(+)), the active metabolite of the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine,

23 e substantia nigra following exposure to the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine,

24 ve effects associated with the mitochondrial neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

25 ormalities, the uptake of monoamines and the neurotoxin 1-methyl-4-phenylpyridinium was significantly

26 etitive OCT1 ligands, of which an endogenous neurotoxin, 1-benzyl-1,2,3,4-tetrahydroisoquinoline, was

27 vented the death of neurons treated with the neurotoxin, 1-methyl-4-phenylpyridinium (MPP(+)), which

28 Injection of the serotonergic neurotoxin 5,7-dihydroxytryptamine into the third ventri

29 Sublethal amounts of the neurotoxin 5,7-dihydroxytryptamine known to specifically

30 -2a and human SH-SY5Y - after treatment with neurotoxin 6-hydroxydopamine (6-OHDA), leading to the bi

31 ative injury following administration of the neurotoxin 6-hydroxydopamine.

32 e obtained when worms were exposed to the DA neurotoxin 6-hydroxydopamine.

33 Botulinum neurotoxin A (BoNT/A) belongs to the most dangerous clas

34 Botulinum neurotoxin A (BoNT/A) has intrinsic endoprotease activit

35 Botulinum neurotoxin A (BoNT/A) induces muscle paralysis by enzyma

36 Botulinum neurotoxin A (BoNT/A) is one of the most deadly toxins a

37 Here we present VHHs against botulinum neurotoxin A (BoNT/A) on the surface of red blood cells

38 lood cells to express VHHs against botulinum neurotoxin A (BoNT/A) on their surface and show that an

39 rapid and sensitive immunoassay of botulinum neurotoxin A (BoNT/A).

40 gned to address the light chain of Botulinum Neurotoxin A and Ricin Toxin A chain, which could be spe

41 scriptional response when exposed to MPTP, a neurotoxin able to mimic the selective cell loss observe

42 g and increased DA neuron survival following neurotoxin administration.

43 r alpha-bungarotoxin and similar snake alpha-neurotoxins also targeting alpha7 nAChR.

44 Acrylamide (AA) is a known lethal neurotoxin and carcinogen.

45 typing since botulism is caused by botulinum neurotoxin and does not require the presence of the bact

46 RNases (EARs): the human eosinophil-derived neurotoxin and eosinophilic cationic protein, and their

47 Using a catecholamine-specific neurotoxin and hyperinsulinemic-hypoglycemic clamps, we

48 e oligomeric (oAbeta), considered a proximal neurotoxin and neuroinflammatory stimuli.

49 Acrylamide is a neurotoxin and potential carcinogen, but is found in var

50 ented the deleterious effects exerted by the neurotoxin and related metabolite quinolinic acid (QUIN)

51 inal type of experiment, the potency of pure neurotoxin and toxin complex was compared in animals pre

52 ility to copper, a metal that in excess is a neurotoxin and whose depletion constitutes a micronutrie

53 re it serves as a precursor to siderophores, neurotoxins and antibiotics.

54 early aggregation process are believed to be neurotoxins and causative agents in Alzheimer disease.

55 Spider venom neurotoxins and cytolytic peptides are expressed as elon

56 he scallop uses hepatopancreas to accumulate neurotoxins and kidney to transform to high-toxicity for

57 3FTx) family, with high sequence identity to neurotoxins and low identity to the well-characterized 3

58 t role in protecting the brain from cationic neurotoxins and other potentially toxic organic cations.

59 er and energy devices, as well as injectable neurotoxins and soft-tissue augmentation materials, amon

60 c dermatologic procedures, including energy, neurotoxin, and filler procedures, are safe when perform

61 dy demonstrates the suitability of botulinum neurotoxin, and serotype D in particular, as a basis for

62 Spider neurotoxins are commonly used as pharmacological tools a

63 We determined that all three neurotoxins are enzymatically active.

64 Botulinum neurotoxins are known to have seven serotypes (BoNT/A-G)

65 Peptide neurotoxins are powerful tools for research, diagnosis,

66 Botulinum neurotoxins are the most poisonous substances known to h

67 Botulinum neurotoxins are the most toxic of all compounds.

68 Neurotoxins associated with Parkinson's disease fully en

69 idium botulinum and associates with nontoxic neurotoxin-associated proteins to form high-molecular we

70 ble treatment antitoxin which can target the neurotoxin at the extracellular level and cannot reverse

71 tive to the therapeutic effects of botulinum neurotoxin B (BoNT/B) than the animal models it is teste

72 replacing it with M/C/V/Q enhances botulinum neurotoxin B binding to human synaptotagmin II.

73 Mutant botulinum neurotoxin B containing E1191M/S1199Y exhibits 11-fold

74 g neurotransmission than wild-type botulinum neurotoxin B in neurons expressing human synaptotagmin I

75 Botulinum neurotoxin B is a Food and Drug Administration-approved

76 The engineered botulinum neurotoxin B provides a platform to develop therapeutic

77 g affinity to h-Syt II may improve botulinum neurotoxin B's therapeutic efficacy and reduce adverse e

78 arget influenza haemagglutinin and botulinum neurotoxin B, along with 6,286 control sequences to prob

79 en in the Syt II-binding pocket of botulinum neurotoxin B.

80 JCI, Selvaraj et al. report that in a mouse neurotoxin-based model of PD, reduced Ca2+ influx throug

81 The steroidal neurotoxin (-)-batrachotoxin functions as a potent agoni

82 domain and replacing it with a C. botulinum neurotoxin binding domain.

83 rs were co-transported with both the tetanus neurotoxin-binding fragment and the membrane proteins th

84 First, clostridial neurotoxins block neurotransmission to or from neurons b

85 Tetanus neurotoxin (TeNT) and botulinum neurotoxin (BoNT) are clostridial neurotoxins (CNTs) res

86 Botulinum neurotoxin (BoNT) binds to and internalizes its light ch

87 Botulinum neurotoxin (BoNT) detection provides a useful model for

88 ensitive detection of highly toxic botulinum neurotoxin (BoNT) from Clostridium botulinum is of criti

89 mats was quantified and the type of botulism neurotoxin (bont) genes associated with this organism we

90 t germinate, multiply, and produce botulinum neurotoxin (BoNT) in the immature intestine.

91 laccid paralysis of muscles due to botulinum neurotoxin (BoNT) intoxication.

92 Botulinum neurotoxin (BoNT) is produced by Clostridium botulinum a

93 ic disease caused by the action of botulinum neurotoxin (BoNT) on nerve cells.

94 Botulinum neurotoxin (BoNT) serotype A is the most lethal known to

95 covered which produces two toxins: botulinum neurotoxin (BoNT) serotype B and a novel BoNT reported a

96 c method for the detection of four botulinum neurotoxin (BoNT) serotypes responsible for human botuli

97 different sdAb specific for the 7 botulinum neurotoxin (BoNT) serotypes, enabling recognition of the

98 simultaneous on-site detection of botulinum neurotoxin (BoNT) types A, B, and E in complex matrixes,

99 ny of the seven known serotypes of botulinum neurotoxin (BoNT), all of which disrupt synaptic transmi

100 east one of the seven serotypes of botulinum neurotoxin (BoNT/A-G).

101 ic proteins for humans and include botulinum neurotoxins (BoNT) and tetanus neurotoxin (TeNT).

102 Botulinum neurotoxins (BoNT) are the most potent toxins known and

103 Botulinum neurotoxins (BoNT/A-G) act by blocking synaptic vesicle

104 mics approach, we report here that all three neurotoxins, BoNT/A2, /F4, and /F5, are produced by C. b

105 Botulinum neurotoxins (BoNTs) and tetanus neurotoxin (TeNT) are th

106 Botulinum neurotoxins (BoNTs) and tetanus toxin (TeNT) are the mos

107 Botulium neurotoxins (BoNTs) are among the most lethal toxins kno

108 Botulinum neurotoxins (BoNTs) are among the most poisonous biologi

109 Botulinum neurotoxins (BoNTs) are highly potent bacterial proteins

110 Botulinum neurotoxins (BoNTs) are highly potent toxins that cleave

111 Botulinum neurotoxins (BoNTs) are produced by various species of c

112 Botulinum neurotoxins (BoNTs) are synthesized by Clostridium botul

113 Botulinum neurotoxins (BoNTs) are the most toxic proteins for huma

114 Botulinum neurotoxins (BoNTs) are the most toxic substances known.

115 Botulinum neurotoxins (BoNTs) are used in a wide variety of medica

116 Botulinum neurotoxins (BoNTs) are zinc endopeptidases that block r

117 Botulinum neurotoxins (BoNTs) cleave SNARE proteins in motor neuro

118 How botulinum neurotoxins (BoNTs) cross the host intestinal epithelial

119 Botulinum neurotoxins (BoNTs) form a large class of potent and dea

120 Botulinum neurotoxins (BoNTs) possess unique specificity for nerve

121 Botulinum neurotoxins (BoNTs) produced by Clostridium botulinum ar

122 Clostridium botulinum produces botulinum neurotoxins (BoNTs), highly potent substances responsibl

123 Botulinum neurotoxins (BoNTs), the most potent toxins known, are p

124 Botulinum neurotoxins (BoNTs), which are highly toxic proteins res

125 of the dinoflagellate Karenia brevis and its neurotoxin, brevetoxin (PbTx).

126 It produces potent neurotoxins (brevetoxins [PbTxs]), which negatively impa

127 eveloping fetuses are most at risk from this neurotoxin but health effects of highly exposed populati

128 ng neuronal resistance to Alphabeta or other neurotoxins by decreasing mitochondrial activity and sub

129 ay increase human exposure to MeHg, a potent neurotoxin, by increasing MeHg production as well as bio

130 calcium-dependent and inhibited by botulinum neurotoxin C, demonstrating the involvement of SNARE-dep

131 not when syntaxin-1 is cleaved by botulinum neurotoxin C.

132 ory failure, ultimately resulting in reduced neurotoxin clearance along the optic nerves, could be an

133 The clostridial neurotoxins (CNTs) are the most toxic proteins for human

134 botulinum neurotoxin (BoNT) are clostridial neurotoxins (CNTs) responsible for the paralytic disease

135 Cyclic imine neurotoxins competitively inhibit biotinylated-alpha-bun

136 num HA is a component of the large botulinum neurotoxin complex and is critical for its oral toxicity

137 Cyclic imine neurotoxins constitute an emergent family of neurotoxins

138 convert the inactive prodrug Daun02 into the neurotoxin daunorubicin.

139 inals exposed to spider or snake presynaptic neurotoxins degenerate as a result of calcium overload a

140 ne-coated nanoparticle (RBCNP) with a unique neurotoxin-derived targeting moiety.

141 of nanomolar concentrations of cyclic imine neurotoxins directly in shellfish samples.

142 Zalophus californianus) exposed to the algal neurotoxin domoic acid are treated in veterinary rehabil

143 reconstituted evoked exocytosis in botulinum neurotoxin E-treated neurons.

144 was developed for the detection of botulinum neurotoxin-E (BoNT/E).

145 leukotrienes (CysLT), and eosinophil-derived neurotoxin (EDN) release.

146 ilia and IL-5, IL-13, and eosinophil-derived neurotoxin (EDN), which stayed consistent after 6 weeks.

147 Human LYNX1, belonging to the Ly6/neurotoxin family of three-finger proteins, is membrane-

148 Mercury is a potent neurotoxin for humans, particularly if the metal is in t

149 Although botulinum neurotoxin for refractory bladder pain syndrome/intersti

150 Luteovirid coat protein-insect neurotoxin fusions represent a promising strategy for tr

151 lostridial organism containing more than two neurotoxin gene clusters.

152 Clostridium botulinum strain Af84 has three neurotoxin gene clusters: bont/A2, bont/F4, and bont/F5.

153 The neurotoxin genes were then deleted independently in the

154 xin fulfills a plethora of functions such as neurotoxin, gliotoxin, and proinflammatory mediator, and

155 ethylation, however, SAM is converted to the neurotoxin homocysteine and must be excreted or drawn ba

156 e versuta (Blue Mountains funnel-web spider) neurotoxin (Hvt) and onion leaf lectin, in tobacco (Nico

157 MeHg as a neurotoxin impacts on the human central nervous systems

158 ound that expression of four insect specific neurotoxins improved the efficacy of M. acridum against

159 For facial injections of neurotoxin in saline, 30-gauge needles were associated w

160 first time that, during exposure to an HIV-1 neurotoxin in vivo, alteration of GluN2B-containing NMDA

161 betaOs), increasingly recognized as proximal neurotoxins in AD, impair organelle transport in culture

162 eta peptide have been implicated as proximal neurotoxins in Alzheimer's disease.

163 and degeneration as well as accumulation of neurotoxins in brain such as beta-amyloid (Abeta) in Alz

164 f amyloid-beta (Abeta) oligomers, AD-related neurotoxins, in the brains of rats and adult nonhuman pr

165 notoxin ImI and a chimeric Naja oxiana alpha-neurotoxin indicating that the major role in alpha-Ctx b

166 fed on these fusion proteins showed signs of neurotoxin-induced paralysis.

167 nd PLD1 positively control fusion of tetanus neurotoxin insensitive vesicle-associated membrane prote

168 Tetanus neurotoxin-insensitive vesicular-associated membrane pro

169 cision placement of agents (e.g., tracers or neurotoxins) into small brain regions of the infant and

170 ut less well understood aspects of botulinum neurotoxin intoxication.

171 peptide (AbetaOs) are thought to be proximal neurotoxins involved in early neuronal oxidative stress

172 Botulinum neurotoxin is considered as one of the most toxic food-b

173 e, convenient, and rapid assay for botulinum neurotoxins is therefore highly desirable for addressing

174 though its contamination by mercury, a known neurotoxin, is a growing concern.

175 Tetrodotoxin (TTX), a small molecular weight neurotoxin, is responsible for poisoning events that tra

176 sTx-1 exhibits two different functions; as a neurotoxin it inhibits L-type Ca(2+) channels, and as a

177 tamate analogs, like the classic excitotoxic neurotoxins kainic acid, domoic acid, and NMDA; the ther

178 Domoic acid (DA) is a naturally occurring neurotoxin known to harm marine animals.

179 manganese and zinc, and higher uptake of the neurotoxin lead.

180 The botulinum neurotoxin light chain (LC) protease has become an impor

181 Potent neurotoxins like tetrodotoxin (TTX) and saxitoxin (STX)

182 Glycosylphosphatidylinositol-anchored neurotoxin-like receptor binding proteins, such as lynx

183 The neurotoxin-like region of the rabies virus glycoprotein

184 y some other three-finger toxins, long alpha-neurotoxin Ls III and nonconventional toxin WTX.

185 ains 7, 8, and 9 of the highly potent marine neurotoxin maitotoxin (1), the largest secondary metabol

186 streamwater concentrations and export of the neurotoxin methyl mercury (MeHg) to freshwater ecosystem

187 t receives gestational exposure (E17) to the neurotoxin methylazoxymethanol (MAM).

188 Microbial production of the bioaccumulative neurotoxin methylmercury (MeHg) is stimulated in newly f

189 c trace metal into the highly bioaccumulated neurotoxin methylmercury (MeHg).

190 ributes to the bioaccumulation of the potent neurotoxin methylmercury in the marine food web.

191 LTCC blockers were neuroprotective in mouse neurotoxin models of PD, and isradipine is currently und

192 gainst anatoxin-a (ATX), the smallest potent neurotoxin (Mol.

193 se species contain the highest levels of the neurotoxin monomethylmercury (MMHg) and therefore presen

194 eria that produce the potent bioaccumulative neurotoxin monomethylmercury remains one of the greatest

195 PD neurotoxin MPP(+) inhibits neddylation of both parkin an

196 P2D6 are fully capable of activating the pro-neurotoxin MPTP and inducing neuronal damage, which is e

197 and astrocytic inflammatory responses to the neurotoxin MPTP and reduced striatal dopamine turnover.

198 in different lineages to function as potent neurotoxins, myotoxins, or hemotoxins.

199 nd female P301S tau transgenic mice with the neurotoxin N-(2-chloroethyl)-N-ethyl-bromobenzylamine (D

200 Monomethylmercury (MMHg) is a neurotoxin of concern in the Canadian Arctic due to its

201 neurotoxins constitute an emergent family of neurotoxins of dinoflagellate origin that are potent ant

202 Insect neurotoxins offer an alternative to chemical insecticide

203 we studied the effect of this environmental neurotoxin on PP2A activity and tau hyperphosphorylation

204 < 0.001, r = 0.7353] and eosinophil-derived neurotoxin [p < 0.01, r = 0.7059]).

205 Annonaceous acetogenins (AAGs) are neurotoxins possibly responsible for atypical Parkinsoni

206 Here we describe the purification of a neurotoxin precursor processing protease from the venom

207 y of the protease in propeptide removal from neurotoxin precursors by cleavage C-terminal of the PQM.

208 es mimicking the predicted cleavage sites of neurotoxin precursors.

209 ns, the genes of a specialized heterodimeric neurotoxin predate the origin of rattlesnakes and were p

210 Domoic acid is a potent neurotoxin produced by certain marine microalgae that ca

211 The HIV-1 Tat protein is a potent neurotoxin produced during HAND that induces activation

212 Methylmercury is a potent neurotoxin produced in natural environments from inorgan

213 Outbreaks are caused by bird ingestion of neurotoxins produced by Clostridium botulinum, a spore-f

214 e first report of three enzymatically active neurotoxins produced in a single strain of Clostridium b

215 The highly poisonous botulinum neurotoxins, produced by the bacterium Clostridium botul

216 samples were tested for botulinum toxin and neurotoxin-producing Clostridium species.

217 epod Calanus finmarchicus co-occurs with the neurotoxin-producing dinoflagellate, Alexandrium fundyen

218 this paper we present a scheme for modelling neurotoxin production in C. botulinum Group I type A1, b

219 ship between HIV replication, HO-1 loss, and neurotoxin production in MDM that likely reflects proces

220 crophage HO-1 deficiency, and the associated neurotoxin production, is a conserved feature of infecti

221 does not prevent HO-1 loss or the associated neurotoxin production.

222 red to detect the trace amount of endogenous neurotoxin (QA).

223 be for the selective detection of endogenous neurotoxin quinolinic acid (QA) whose elevated level in

224 The neurotoxin quinolinic acid may impair blood-brain barrie

225 rtant neuroactive metabolites, including the neurotoxin, quinolinic acid (QUIN), the neuroprotective

226 toxin (TTX) is one of the most potent marine neurotoxins reported.

227 ration is induced by some animal presynaptic neurotoxins, representing an appropriate and controlled

228 icardial application of a selective afferent neurotoxin, resiniferatoxin, selectively lowered diastol

229 errence against predation, while it achieves neurotoxin resistance through point mutations in sodium

230 r muscle, sophisticated eyes, and remarkable neurotoxin resistance.

231 Pseudomonas aeruginosa exotoxin A, Botulinum neurotoxin, ricin, and Zika virus.

232 pression changes induced by the Parkinsonian neurotoxin rotenone and opposed by those induced by clio

233 AR by epicardial application of the afferent neurotoxin, RTX, selectively lowered diastolic blood pre

234 -beta-hydroxylase antibody conjugated to the neurotoxin saporin (DSAP) or saline vehicle was microinj

235 us animals such as scorpions produce diverse neurotoxins selected to hit targets in the nervous syste

236 en-labelled studies have suggested botulinum neurotoxin serotype A (BoNT-A) to be an effective treatm

237 Botulinum neurotoxin serotype A (BoNT/A) causes a debilitating and

238 (4,7-ACQ) based inhibitors of the botulinum neurotoxin serotype A (BoNT/A) light chain were synthesi

239 says for colorimetric detection of botulinum neurotoxin serotype A light chain (BoLcA).

240 analogues of dual antimalarial and botulinum neurotoxin serotype A light chain (BoNT/A LC) inhibitor

241 gosaccharide GD1a can associate to botulinum neurotoxin serotype A when expressed as individual trisa

242 ate minimal binding epitope of the botulinum neurotoxin serotype A.

243 Stichodactyla helianthus neurotoxin (ShK) is an immunomodulatory peptide currentl

244 d and functionally characterized to date are neurotoxins specifically targeted to receptors, ion chan

245 agent vincristine, antimalarial quinine and neurotoxin strychnine, are synthesized in several differ

246 orescent recognition agent for the botulinum neurotoxin subtype A (BoNT/A) using the virtual screenin

247 oxicity is indirect, resulting from released neurotoxins such as the HIV-1 protein transactivator of

248 Tetanus neurotoxin (TeNT) and botulinum neurotoxin (BoNT) are cl

249 Botulinum neurotoxins (BoNTs) and tetanus neurotoxin (TeNT) are the most toxic proteins for humans

250 Tetanus neurotoxin (TeNT) causes neuroparalytic disease by enter

251 Tetanus neurotoxin (TeNT) is among the most poisonous substances

252 AREs (synaptobrevins/VAMP1/2/3 using tetanus neurotoxin (TeNT), also in TI-VAMP/VAMP7 knock-out (KO)

253 ude botulinum neurotoxins (BoNT) and tetanus neurotoxin (TeNT).

254 ignificant capacity to store psychosine, the neurotoxin that accumulates in Krabbe disease.

255 Gambierol is a potent neurotoxin that belongs to the family of marine polycycl

256 elevated loadings of methylmercury (MeHg; a neurotoxin that biomagnifies through foodwebs) due to oi

257 Mercury (Hg) is a neurotoxin that can be particularly harmful to top preda

258 Here, we show that a neurotoxin that causes a disease that mimics PD upon adm

259 eurotoxin type A (BoNT/A) is a highly potent neurotoxin that elicits flaccid paralysis by enzymatic c

260 Methylmercury (MeHg) is a potent neurotoxin that has been demonstrated to biomagnify in A

261 with 1-methyl-4-phenylpyridinium (MPP(+)), a neurotoxin that inhibits complex I of electron transport

262 Methylmercury (MeHg) is a potent neurotoxin that is biomagnified approximately 1-10 milli

263 Ammonia is a potent neurotoxin that is detoxified mainly by the urea cycle i

264 -tetrahydropyridine (MPTP) is a dopaminergic neurotoxin that replicates most of the clinical features

265 xicity of the venom is mainly due to various neurotoxins that belong to two distinct structural and i

266 llate produces brevetoxins, which are potent neurotoxins that cause neurotoxic shellfish poisoning an

267 Brevetoxins (BTXs) are very potent marine neurotoxins that increased in geographical distribution

268 Neurotoxins that mimic Parkinson's disease increased Cav

269 Neurotoxins that mimic Parkinson's disease target TRPC1

270 ellate Karenia brevis, which produces potent neurotoxins that negatively impact coastal marine ecosys

271 alpha-Conotoxins are disulfide-rich peptide neurotoxins that selectively inhibit neuronal nicotinic

272 t North American rattlesnakes do not produce neurotoxins, the genes of a specialized heterodimeric ne

273 etwork excitability in the presence of HIV-1 neurotoxins; these changes may inform the development of

274 ate-receptor binding assay, the cyclic imine neurotoxins tightly bound to the coated Torpedo nicotini

275 iche, starting by middle age, amplified upon neurotoxin treatment and associated with an exacerbated

276 Neurotoxin treatment decreased TRPC1 expression, TRPC1 i

277 sensitive detection of Clostridium botulinum Neurotoxin Type A (BoNT/A) in complex, real-world media.

278 Botulinum neurotoxin type A (BoNT/A) is a highly potent neurotoxin

279 ssociated protein 25 (SNAP-25) for botulinum neurotoxin type A (BoNT/A).

280 012 is a recombinant derivative of Botulinum neurotoxin Type A (BoNT/A).

281 ent with infant botulism, produced botulinum neurotoxin type B (BoNT/B) and another BoNT that, by use

282 The botulinum neurotoxin type D is one of seven highly potent toxins p

283 Botulinum neurotoxin type E (BoNT/E) is a member of a family of se

284 ent was prevented by expression of botulinum neurotoxin type E.

285 duces the recently described novel botulinum neurotoxin type H (BoNT/H).

286 e of 62 (SD 22) treatments of 70.2 (SD 20.8) neurotoxin units.

287 d by examining the enzymatic activity of the neurotoxins upon peptide substrates, which mimic the tox

288 tect against dopaminergic deficits caused by neurotoxins via increased neurogenesis in the subventric

289 eurocognitive diseases through metabolism to neurotoxins via the kynurenine pathway, a role for kynur

290 In the first, the potency of pure neurotoxin was compared with that of progenitor toxin co

291 The enzymatic activity of all three neurotoxins was assessed by examining the enzymatic acti

292 aightforward detection between OP and non-OP neurotoxins was successfully achieved with cyclic voltam

293 Using a selective neurotoxin, we also demonstrate differential drive of th

294 and antagonist responses nicotine and known neurotoxins were detected from tobacco extract and snake

295 rticular interest as methylmercury (MeHg), a neurotoxin which bioaccumulates through foodwebs, can re

296 various species of clostridia and are potent neurotoxins which cause the disease botulism, by cleavin

297 mercury (MeHg(+) ) is one of the most potent neurotoxins, which damages the brain and nervous system

298 and epitope, and these compounds bind to the neurotoxin with a high degree of predisposition but with

299 is the first discovery of a single botulinum neurotoxin with BoNT/A antigenicity and BoNT/F light cha

300 supernatants and tested each immune-captured neurotoxin with full-length substrates vesicle-associate