ライフサイエンスコーパス: neurotrophic

1 -12 and MEK inhibitor PD98059 attenuates the neurotrophic action of compounds.

2 ulminated in a formal total synthesis of the neurotrophic agent (-)-jiadifenolide.

3 an anti-inflammatory agent (minocycline), a neurotrophic agent (LM11A-31), and physical therapy cons

4 Results revealed significant benefits of the neurotrophic agent LM11A-31 on learning and memory outco

5 cts of ES, including increased production of neurotrophic agents, improved chorioretinal blood circul

6 n technology for therapeutic delivery of key neurotrophic agents.

7 g demonstrated expression of transcripts for neurotrophic and angiogenic factors, as well as JUN, all

8 and increase expression of genes that encode neurotrophic and gliogenic proteins.

9 inflammatory, and trophic factors along with neurotrophic and neurogenesis factors were detected; the

10 to treat neuropsychiatric disorders wherein neurotrophic and neurogenic properties are affected, two

11 furanodiene, which appears to be a promising neurotrophic and neuroprotective agent deserving further

12 dermal differentiation, and that it has both neurotrophic and neuroprotective functions.

13 while the other one is more neurogenic than neurotrophic and the former exhibits remarkable neuropro

14 dding of their secreted ectodomains, such as neurotrophic APPsalpha.

15 es of the dopaminergic (COMT, ANKK1) and the neurotrophic (BDNF, NGFR) system, associations with the

16 These results suggest that IL-17c is a neurotrophic cytokine that protects peripheral nerve sys

17 Keratoconus is characterized by a neurotrophic deficit and altered nerve morphology that C

18 It is unknown whether a neurotrophic deficit or pathologic nerve morphology pers

19 tin and ghrelin and likely involves a direct neurotrophic effect of Magel2.

20 hrelin blunted axonal growth and blocked the neurotrophic effect of the adipocyte-derived hormone lep

21 e memantine might have anti-inflammatory and neurotrophic effects mechanistically remote from an NMDA

22 gs reveal distinct small PEDF fragments with neurotrophic effects on photoreceptors.

23 , as well as PIK3C3, have anti-apoptotic and neurotrophic effects, are decreased in expression in sui

24 were inversely associated with brain-derived neurotrophic factor (BDNF) (p < 0.05), and interquartile

25 euromuscular changes depend on brain-derived neurotrophic factor (BDNF) acting through the tropomyosi

26 Membrane depolarization, brain-derived neurotrophic factor (BDNF) and forskolin activate distin

27 Brain-derived neurotrophic factor (BDNF) and its high affinity recepto

28 Brain-derived neurotrophic factor (BDNF) and its receptor TrkB are cru

29 Brain-derived neurotrophic factor (BDNF) and its TrkB receptor are kno

30 B to 2A, which is dependent on brain-derived neurotrophic factor (BDNF) and metabotropic glutamate re

31 Neurotrophins particularly brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF)

32 dent structural plasticity via brain-derived neurotrophic factor (BDNF) and protein neo-synthesis.

33 Expression of brain-derived neurotrophic factor (BDNF) and somatostatin (SST) mRNAs

34 aimed to evaluate the role of brain-derived neurotrophic factor (BDNF) and tyrosine receptor kinase

35 e [BrdU]) and those expressing brain-derived neurotrophic factor (BDNF) and vimentin, a marker for ra

36 ypothesized that cytokines and brain-derived neurotrophic factor (BDNF) are biomarkers for BP.

37 f ovarian steroid hormones and brain-derived neurotrophic factor (BDNF) are highly convergent on brai

38 5-hydroxytryptamine, 5-HT) and brain-derived neurotrophic factor (BDNF) are two signaling molecules t

39 pendent effects on hippocampal brain-derived neurotrophic factor (BDNF) BDNF-IX, BDNF-IV and BDNF-I t

40 In particular, we knocked down brain-derived neurotrophic factor (Bdnf) bilaterally in the OFC or gen

41 ility, and increased levels of brain-derived neurotrophic factor (BDNF) but produced no significant c

42 by modulating the secretion of brain-derived neurotrophic factor (BDNF) by pulp fibroblasts.

43 Because brain-derived neurotrophic factor (BDNF) can modulate vestibular funct

44 myostatin (3-fold) and lowered brain-derived neurotrophic factor (BDNF) expression (0.6-fold) in the

45 ion resulted in an increase in brain-derived neurotrophic factor (BDNF) expression and a reduction in

46 Cocaine exposure alters brain-derived neurotrophic factor (BDNF) expression in the brain.

47 urthermore, while sustained PL brain-derived neurotrophic factor (BDNF) expression is required for me

48 revealed a correlation between brain-derived neurotrophic factor (BDNF) expression, nerve density, an

49 rons; synthesis and release of brain-derived neurotrophic factor (BDNF) from WT cortical axons were r

50 ation of a NOTCH inhibitor and brain-derived neurotrophic factor (BDNF) further directed the cells in

51 raexonic splicing event in the brain-derived neurotrophic factor (BDNF) gene generates a truncated mR

52 amine are thought to depend on brain-derived neurotrophic factor (BDNF) genotype and dose.

53 Brain-derived neurotrophic factor (BDNF) has a crucial role in learnin

54 Brain-derived neurotrophic factor (BDNF) has a crucial role in modulat

55 The over-expressed colonic brain-derived neurotrophic factor (BDNF) has been reported to be assoc

56 One member, brain-derived neurotrophic factor (BDNF) has drawn much attention due

57 The biosynthesis of endogenous brain-derived neurotrophic factor (BDNF) has thus far been examined in

58 trograde axonal trafficking of brain-derived neurotrophic factor (BDNF) in DIV7 cultures of E18 corti

59 Brain-derived neurotrophic factor (BDNF) in particular can confer neur

60 cuits, we examined the role of brain-derived neurotrophic factor (BDNF) in the assembly of GABAergic

61 Results Protein expressions of brain-derived neurotrophic factor (BDNF) in the BCCAO rats treated wit

62 control the expression of the brain-derived neurotrophic factor (BDNF) in the prefrontal cortex (PFC

63 was to investigate the role of brain-derived neurotrophic factor (BDNF) in the regenerative ability o

64 Low levels of brain-derived neurotrophic factor (BDNF) increase the desensitization

65 ions at the promoter region of brain-derived neurotrophic factor (BDNF) increased, which was accompan

66 idepressant response including brain-derived neurotrophic factor (BDNF) induction and increased phosp

67 Brain-derived neurotrophic factor (BDNF) is a critical effector of dep

68 es suggest that dysfunction of brain-derived neurotrophic factor (BDNF) is a possible contributor to

69 Brain-derived neurotrophic factor (BDNF) is among the key regulators t

70 Brain-derived neurotrophic factor (BDNF) is an active neurotrophin abu

71 Brain-derived neurotrophic factor (BDNF) is critical for mammalian dev

72 Brain-derived neurotrophic factor (BDNF) is essential for neuronal dif

73 Brain-derived neurotrophic factor (BDNF) is expressed in gustatory epi

74 In this study, we show brain-derived neurotrophic factor (BDNF) is required for the antimanic

75 he following: (1) enhances the brain-derived neurotrophic factor (BDNF) level in the brain; (2) reduc

76 of the rats and measured their brain-derived neurotrophic factor (BDNF) levels as a proxy of neuronal

77 Low serum brain-derived neurotrophic factor (BDNF) levels measured before SE ide

78 growth factor (TGF)-beta1, and brain-derived neurotrophic factor (BDNF) levels were examined during w

79 Reduced brain-derived neurotrophic factor (BDNF) may underlie age-related syna

80 c sympatho-inhibitory role for brain-derived neurotrophic factor (BDNF) neurotransmission in the dmNT

81 on, the enhancement effects of brain-derived neurotrophic factor (BDNF) on the local protein synthesi

82 ated the relationships between brain-derived neurotrophic factor (BDNF) plasma concentrations and the

83 n that neurotrophins including brain-derived neurotrophic factor (BDNF) play a role in chronic inflam

84 Brain-derived neurotrophic factor (BDNF) plays a key role in the patho

85 does temporary treatment with brain-derived neurotrophic factor (BDNF) prevent nerve degeneration on

86 annabinoid receptor type 1 and brain-derived neurotrophic factor (BDNF) protein levels were measured.

87 essant ketamine: activation of brain-derived neurotrophic factor (BDNF) receptor TrkB, facilitation o

88 caused by upregulation of the brain-derived neurotrophic factor (BDNF) receptor trkB.T1, a truncated

89 mediated by activation of the brain-derived neurotrophic factor (BDNF) receptor tropomysin-related k

90 Brain-derived neurotrophic factor (BDNF) regulates diverse biological

91 Brain-derived neurotrophic factor (BDNF) regulates neuronal survival a

92 At the molecular level, brain derived-neurotrophic factor (BDNF) represents an important playe

93 (Met) polymorphism within the brain-derived neurotrophic factor (BDNF) sequence reduces activity-dep

94 Brain-derived neurotrophic factor (BDNF) signaling in the dorsolateral

95 ucocorticoid receptors (GR) by brain-derived neurotrophic factor (BDNF) signaling integrates both pat

96 Brain-derived neurotrophic factor (BDNF) signaling through TrkB recept

97 Here we show that brain-derived neurotrophic factor (BDNF) signaling through tyrosine ki

98 er, we describe a key role for brain-derived neurotrophic factor (BDNF) that is produced in the brain

99 tor p75(NTR), required for pro-brain-derived neurotrophic factor (BDNF) to induce long-term depressio

100 OMMENTARY ON THIS ARTICLE: The brain-derived neurotrophic factor (BDNF) Val66Met polymorphism is impl

101 a candidate gene study on the Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism, a gene

102 evealed that the gene encoding brain-derived neurotrophic factor (BDNF) was associated with ADHD at B

103 dditionally, the expression of brain-derived neurotrophic factor (BDNF) was markedly decreased in the

104 owed enhanced vulnerability to brain-derived neurotrophic factor (BDNF) withdrawal in the juvenile-on

105 ein and abnormal expression of brain-derived neurotrophic factor (BDNF), a key modulator of neuronal

106 Brain-derived neurotrophic factor (BDNF), a key player in regulating s

107 Brain-derived neurotrophic factor (BDNF), a member of the neurotrophin

108 Brain-derived neurotrophic factor (BDNF), a promising neurotrophic fac

109 Brain-derived neurotrophic factor (BDNF), a protein important to nervo

110 nes [e.g., SRY-box 21 (Sox21), brain-derived neurotrophic factor (Bdnf), and growth arrest and DNA-da

111 trol) treatment increased NGF, brain-derived neurotrophic factor (BDNF), and IL-1beta gene expression

112 anin and neuropeptide Y (NPY), brain-derived neurotrophic factor (BDNF), as well as neuroinflammatory

113 hrough increasing the level of brain-derived neurotrophic factor (BDNF), but the underlying mechanism

114 of nerve growth factor (NGF), brain derived neurotrophic factor (BDNF), neurotrophin 3 (NT3), and ne

115 ed neurotrophic factor (GDNF), brain-derived neurotrophic factor (BDNF), pleiotrophin (PTN), and NT-3

116 sed for measuring the level of brain-derived neurotrophic factor (BDNF), the expression and activity

117 facilitation of plasticity by brain-derived neurotrophic factor (BDNF), the postsynaptic source of w

118 s is to synthesize and release brain-derived neurotrophic factor (BDNF), which is vital for neuronal

119 thelial cells (HUVECs) secrete brain-derived neurotrophic factor (BDNF), which significantly stimulat

120 on of rat VP neurons through a brain-derived neurotrophic factor (BDNF)-dependent activation of TrkB

121 report that Slitrk5 modulates brain-derived neurotrophic factor (BDNF)-dependent biological response

122 the involvement of the MNKs in brain-derived neurotrophic factor (BDNF)-stimulated protein synthesis

123 the retrograde trafficking of brain-derived neurotrophic factor (BDNF)-TrkB complexes and also regul

124 nesis, and increased levels of brain-derived neurotrophic factor (BDNF).

125 r or superior to the effect of brain-derived neurotrophic factor (BDNF).

126 ticity-associated neurotrophin brain-derived neurotrophic factor (BDNF).

127 d with increased risk, such as brain-derived neurotrophic factor (BDNF).

128 in SZ, including the gene for brain-derived neurotrophic factor (BDNF).

129 ly practicable) treatment with brain-derived neurotrophic factor (BDNF).

130 includes endocannabinoids and brain-derived neurotrophic factor (BDNF).

131 kinase TRKB, the receptor for brain-derived neurotrophic factor (BDNF).

132 (rs6265) in the human gene for brain derived neurotrophic factor (BDNF).

133 cells to produce pro-survival brain derived neurotrophic factor (BDNF).

134 egulated miRNAs, downstream of brain-derived neurotrophic factor (BDNF).

135 TP) that requires postsynaptic brain-derived neurotrophic factor (BDNF)/TrkB and presynaptic cyclic A

136 c plasticity markers including brain derived neurotrophic factor (BNDF) and phosphorylated CREB, both

137 Cerebral dopamine neurotrophic factor (CDNF) is a promising therapeutic ag

138 Exogenous ciliary neurotrophic factor (CNTF) administration promotes the s

139 likely trigger of such sprouting is ciliary neurotrophic factor (CNTF) expressed in local spinal neu

140 ng DCs, which were a major source of ciliary neurotrophic factor (CNTF) in the cornea.

141 to early postnatal treatment with a ciliary neurotrophic factor (CNTF) small-molecule peptide mimeti

142 s of hepatocyte growth factor (HGF), ciliary neurotrophic factor (CNTF), and Artemin through specific

143 /insulin-like growth factor 1 (IGF1)/ciliary neurotrophic factor (CNTF), induces regrowth of retinal

144 es mediates endogenous production of ciliary neurotrophic factor (CNTF), which prevents the active de

145 Glial cell line-derived neurotrophic factor (GDNF) binds GDNF family receptor al

146 ceptor tyrosine kinase for the glial derived neurotrophic factor (GDNF) family ligands (GFLs), during

147 apeutic potential of glial cell line-derived neurotrophic factor (GDNF) has been studied extensively

148 iphasic function for glial cell line-derived neurotrophic factor (GDNF) in the development and subseq

149 Glial cell line-derived neurotrophic factor (GDNF) is essential for this process

150 We had previously found that glial derived neurotrophic factor (GDNF) is reduced in SMA astrocytes.

151 Glial cell line-derived neurotrophic factor (GDNF) promotes PNS development and

152 Delivery of ectopic glial cell line-derived neurotrophic factor (GDNF) promotes the function, plasti

153 Here we identify glial cell-derived neurotrophic factor (GDNF) receptor alpha-like (GFRAL) a

154 binding neuropeptide glial-cell-line-derived neurotrophic factor (GDNF) to increase cocaine intake wa

155 tial potency of NGF, glial cell line-derived neurotrophic factor (GDNF), brain-derived neurotrophic f

156 raspinally expressed glial cell line-derived neurotrophic factor (GDNF), but not the removal of chond

157 protein (sAPP)beta, sAPPalpha, glial-derived neurotrophic factor (GDNF), P-T181-tau, and P-S396-tau w

158 axons and they did not express glial derived neurotrophic factor (GDNF), which is essential for fusim

159 ling induced mesencephalic astrocyte-derived neurotrophic factor (MANF) in innate immune cells.

160 Mesencephalic astrocyte-derived neurotrophic factor (MANF) is a neurotrophic factor that

161 Mesencephalic astrocyte-derived neurotrophic factor (MANF) localizes to the ER lumen and

162 ible protein Mesencephalic Astrocyte-derived Neurotrophic Factor (MANF) was up-regulated in autoimmun

163 tinic acetylcholine receptors (nAChR) during neurotrophic factor (NTF)-dependent excitatory synaptoge

164 We report here that pro-brain-derived neurotrophic factor (proBDNF) activates p75NTR to induce

165 We report here that a pro-brain-derived neurotrophic factor (proBDNF)-dependent p75NTR signaling

166 s dopamine, noradrenaline, and brain-derived neurotrophic factor [3-7].

167 ing protein and an increase in brain-derived neurotrophic factor and c-FOS protein levels, key regula

168 f genes, tyrosine hydroxylase, brain-derived neurotrophic factor and FK506 binding protein 5.

169 h the secreted APP ectodomain that acts as a neurotrophic factor and full-length APP forming trans-ce

170 al signaling proteins, such as brain-derived neurotrophic factor and its downstream targets vs. contr

171 We previously showed that brain-derived neurotrophic factor and its receptor, TrkB, in the dorso

172 reted higher concentrations of brain-derived neurotrophic factor and nerve growth factor than NCSC-SC

173 ons that were maintained under subsaturating neurotrophic factor conditions operates under cholinergi

174 via an increase in hippocampal brain-derived neurotrophic factor content.

175 is activated by the glial cell line-derived neurotrophic factor family ligands (GFLs), plays a cruci

176 phic factor receptor glial cell line-derived neurotrophic factor family of receptors-alpha3 (GFRalpha

177 rturin (NRTN), a member of the glial-derived neurotrophic factor family, was identified from an embry

178 Hippocampal concentrations of the neurotrophic factor fibroblast growth factor 2 (FGF2) ar

179 ived neurotrophic factor (BDNF), a promising neurotrophic factor for the treatment of many central ne

180 f a common polymorphism in the brain-derived neurotrophic factor gene (BDNF) provides examples of how

181 eral key genes, including Bdnf, an important neurotrophic factor implicated in HD.

182 The brain derived neurotrophic factor increased in all brain regions with

183 tained increase in hippocampal brain-derived neurotrophic factor level.

184 ropathology, neuroinflammation mediators and neurotrophic factor levels and motor coordination.

185 cerebroventricular infusion of brain-derived neurotrophic factor mimicked the action of hyperbaric ox

186 Here, we describe a mechanism whereby the neurotrophic factor NGF and the transcription factor Run

187 several key components of the brain derived neurotrophic factor pathway that were marked by m6A.

188 report for the first time that brain-derived neurotrophic factor potentiates vestibular neurogenesis

189 in-derived neurotrophic factor/brain-derived neurotrophic factor ratio, which aggravates p75 neurotro

190 T1, a truncated isoform of the brain-derived neurotrophic factor receptor (BDNF), contributes to glio

191 Ciliary neurotrophic factor receptor alpha subunit (CNTFRalpha)

192 herapeutics is abolished in mice lacking the neurotrophic factor receptor glial cell line-derived neu

193 of other important cargoes, such as the p75 neurotrophic factor receptor was minimally altered in mu

194 hat ShcD binds to active Ret, TrkA, and TrkB neurotrophic factor receptors predominantly via its phos

195 ed differentiation, functionality as well as neurotrophic factor release.

196 Over the short term, ciliary neurotrophic factor released continuously from an intrav

197 ) containing a neuropeptide or brain-derived neurotrophic factor shows that the F-actin depolymerizin

198 due to selective impairment of brain-derived neurotrophic factor signaling via its receptor, TrkB.

199 Blockade of hippocampal brain-derived neurotrophic factor signaling with intracerebroventricul

200 o mediate synaptic plasticity, neurogenesis, neurotrophic factor signaling, and inflammatory signalin

201 number of proteins linked with brain-derived neurotrophic factor signaling.

202 understanding on the molecular mechanisms of neurotrophic factor signaling.

203 cyte-derived neurotrophic factor (MANF) is a neurotrophic factor that is also localized in the endopl

204 ing hypothalamic insulin signaling.MANF is a neurotrophic factor that is secreted but also mediates t

205 ncreased Na(+)-channel 1.2 and brain-derived neurotrophic factor transcription and boosted Na(+) curr

206 on was clearly diminished, and brain-derived neurotrophic factor treatment was unable to phosphorylat

207 Tissue level of brain-derived neurotrophic factor was assessed by enzyme-linked immuno

208 inant human TrkB-Fc chimera or brain-derived neurotrophic factor was infused into the lateral ventric

209 amounts (1 pg/ml) of glial cell line-derived neurotrophic factor were included in culture media.

210 CRADD/caspase-2 signaling is implicated in neurotrophic factor withdrawal- and amyloid-beta-induced

211 ntrol cells, mimicked by Bdnf (brain-derived neurotrophic factor) or Dcx RNAi, and rescued by BDNF ap

212 dentified in mesencephalic astrocyte-derived neurotrophic factor, a CDNF paralog, which corresponds t

213 15), whereas pleotropin, FGF5, brain-derived neurotrophic factor, and Dickkopf WNT signaling pathway

214 ased expression of hippocampal brain-derived neurotrophic factor, consistent with impaired ability to

215 anied by reduced expression of brain-derived neurotrophic factor, in the brains 61 weeks after the mi

216 evel in the circulation and of brain-derived neurotrophic factor, phosphorylated tropomyosin-receptor

217 Rather than a conventional peptide neurotrophic factor, we identified a prominent lipid com

218 primary astrocytes to produce brain-derived neurotrophic factor, which does foster cognitive functio

219 pus of these mice showed increased levels of neurotrophic factor-alpha1 (NF-alpha1; also known as car

220 the cognitive impairment in a brain-derived neurotrophic factor-dependent manner.

221 s accompanied by impairment of brain-derived neurotrophic factor-mediated dendritic growth.

222 implicates a role for the pro-brain-derived neurotrophic factor-p75 neurotrophin receptor pathway.

223 , mutant mice display impaired brain-derived neurotrophic factor-tropomyosin receptor kinase B-depend

224 approaches to test the role of brain-derived neurotrophic factor-tropomyosin-related kinase B (BDNF-T

225 cerebroventricular infusion of brain-derived neurotrophic factor.

226 ing of nerve growth factor and brain-derived neurotrophic factor.

227 responses to the neurotrophin brain-derived neurotrophic factor.

228 ing of nerve growth factor and brain-derived neurotrophic factor.

229 ositol 1,4,5-trisphosphate and brain-derived neurotrophic factor.

230 ole played by the neurotrophin brain-derived neurotrophic factor.

231 Propofol enhanced pro-brain-derived neurotrophic factor/brain-derived neurotrophic factor ra

232 including semaphorins [4, 5], brain-derived neurotrophic factors (BDNFs) [6], UNC-6/Netrin [7], and

233 xpression of neural growth and brain derived neurotrophic factors (NGF, BDNF).

234 on relationship studies on this new class of neurotrophic factors and also assist in evaluation of th

235 with apparently normal expression of several neurotrophic factors and normal GDNF signaling.

236 olome profiling, vitamin-D, inflammatory and neurotrophic factors are in progress.

237 These data show that neurotrophic factors can selectively promote the surviva

238 rammed cell death due to a limited supply of neurotrophic factors from their targets.

239 ALS) and that the combined delivery of these neurotrophic factors has a strong synergistic effect.

240 (+) regulatory T cells, and elevation of the neurotrophic factors IGF-1 and GDNF in the diseased spin

241 ramework for the combined therapeutic use of neurotrophic factors in degenerative motor neuron diseas

242 ving DPCs could increase the availability of neurotrophic factors in the lesion site, thereby promoti

243 tion of neuroinflammation and an increase of neurotrophic factors levels was observed, indicating tha

244 te that treatment of the auditory nerve with neurotrophic factors may be relevant for cochlear implan

245 Cs, and up-regulates the expression of their neurotrophic factors mRNA in vitro.

246 nd oligodendrocytes, and increased levels of neurotrophic factors NT-3, GDNF and BDNF.

247 this, we here screened 66 combinations of 12 neurotrophic factors on pure, highly viable, and standar

248 Numerous neurotrophic factors promote the survival of developing

249 osure on oligodendrocyte differentiation and neurotrophic factors secretion.

250 ervous system, they function proximal to the neurotrophic factors that regulate cell survival, differ

251 These data show that HUVECs secrete neurotrophic factors that significantly enhance axonal g

252 The production of major neurotrophic factors was equivalent in FGF2-treated and

253 Neurotrophic factors, a family of secreted proteins that

254 ission, the upregulation of neurogenesis and neurotrophic factors, normalizing hypothalamic-pituitary

255 by producing antiinflammatory cytokines and neurotrophic factors, support myelin production, and rem

256 erve growth has been investigated, including neurotrophic factors, topography, and electrical stimula

257 SMF on the gene expression and secretion of neurotrophic factors- BDNF and NT3 was quantified.

258 sturbances of developing processes involving neurotrophic factors.

259 in the CA3 area and increased expression of neurotrophic factors.

260 matory response to injury and a reduction in neurotrophic factors.

261 ing mesenchymal stem cells (MSCs) to secrete neurotrophic factors.

262 wn, indicating that hUTCs secrete additional neurotrophic factors.

263 eneration of these cells can be averted with neurotrophic factors.

264 olved both immunomodulation and induction of neurotrophic factors.

265 gene for GnRH neuron development, uncover a neurotrophic function for SEMA3E in the developing brain

266 strocytes less effective in supporting these neurotrophic functions than those with APOE epsilon3/eps

267 n biochemical factors, such as brain derived neurotrophic growth factor (BDNF), vascular endothelial

268 Preclinical studies have shown that neurotrophic growth factors (NTFs) extend the survival o

269 roglia exposed to 7KCh reduced expression of neurotrophic growth factors but increased expression of

270 Conversely, the secretion of neurotrophic growth factors by cancer cells drives the o

271 ngs included vitreous amyloid (26/26, 100%), neurotrophic keratitis (2/26, 8%), glaucoma (5/26, 19%),

272 x virus type 1 (HSV-1) is a leading cause of neurotrophic keratitis characterized by decreased cornea

273 lication in the development of HSV-1-induced neurotrophic keratitis.

274 ld, have been thoroughly evaluated for their neurotrophic, neurogenic and neuroprotective potential i

275 The results indicate that leptin loses its neurotrophic potential at or near postnatal day 28.

276 However, the molecular mechanism underlying neurotrophic-priming of GR function is poorly understood

277 Neurotrophic processes including neurogenesis shown in p

278 ting in a fusion between Brevican (BCAN) and Neurotrophic Receptor Tyrosine Kinase 1 (NTRK1), is a po

279 PLD4 binds three proteins that interact with neurotrophic receptor tyrosine kinase 1, a receptor also

280 e propose a model whereby ShcD competes with neurotrophic receptors for Grb2 binding and opposes acti

281 eet-taste receptor system plays an important neurotrophic role in the extralingual central nervous ti

282 An asymmetric approach to the synthesis of neurotrophic seco-prezizaane sesquiterpenes is described

283 vage by alpha-secretase produces potentially neurotrophic secreted APPalpha (sAPPalpha) and the P3 pe

284 O-Debenzoyltashironin (1) is a member of the neurotrophic sesquiterpenes, trace plant metabolites tha

285 a gap in a comparison set of convulsive and neurotrophic sesquiterpenes, which we hypothesized to sh

286 ressing the potential interplay between GDNF neurotrophic signaling and transcriptional regulation in

287 able to restore dysfunctional Ret-dependent neurotrophic signaling in alpha-synuclein-overexpressing

288 sults showed that RXR ligands could increase neurotrophic signaling, but provided a mixed picture of

289 ents required for neuronal survival, such as neurotrophic signaling.

290 ndings provide novel evidence that providing neurotrophic support during early brain development can

291 eneration and promotes Schwann-cell-mediated neurotrophic support in models of peripheral neuropathie

292 hat is triplicated in Down syndrome, impairs neurotrophic support of sympathetic neurons by inhibitin

293 taste cell renewal on gustatory innervation, neurotrophic support of taste buds likely involves a com

294 elopment, sensory axons compete for limiting neurotrophic support, and local neurotrophin insufficien

295 suggest that one of these molecules is more neurotrophic than neurogenic while the other one is more

296 array of biological activities ranging from neurotrophic to anti-inflammatory and anti-tumorigenic p

297 Here we report a concise synthesis of the neurotrophic trace metabolite (-)-jiadifenolide and its

298 c peripheral neuropathy (DPN) often leads to neurotrophic ulcerations in the cornea and skin; however

299 may be warranted against the development of neurotrophic ulcers.

300 Decreases in the ratio of neurotrophic versus neurodegenerative signalling play a