ライフサイエンスコーパス: neurotrophin 4

1 ved neurotrophic factor, neurotrophin-3, and neurotrophin-4.

2 hic factor (BDNF), neurotrophin 3 (NT3), and neurotrophin 4/5 (NT4/5).

3 ng for brain-derived neurotrophic factor and neurotrophin 4/5 was absent from the nerve head and supe

4 rotrophic factor, BDNF; neurotrophin 3, NT3; neurotrophin 4/5, NT4/5; or glial-derived neurotrophic f

5 ived neurotrophic factor, neurotrophin 3, or neurotrophin 4/5.

6 phins, brain-derived neurotrophic factor and neurotrophin 4/5.

7 Both neurotrophin-4/5 (NT-4) and brain-derived neurotrophic f

8 ic factor (BDNF), neurotrophin-3 (NT-3), and neurotrophin-4/5 (NT-4/5) upon ventral mesencephalic dop

9 brain-derived neurotrophic factor (BDNF) and neurotrophin-4/5 (NT-4/5) via TrkB, and neurotrophin-3 (

10 ic factor (BDNF), neurotrophin-3 (NT-3), and neurotrophin-4/5 (NT-4/5), contribute to survival and di

11 brain-derived neurotrophic factor (BDNF) or neurotrophin-4/5 (NT-4/5), or blockade of their endogeno

12 brain derived neurotrophic factor (BDNF) and neurotrophin-4/5 (NT-4/5).

13 brain-derived neurotrophic factor (BDNF) or neurotrophin-4/5 (NT-4/5).

14 brain-derived neurotrophic factor (BDNF) and neurotrophin-4/5 (NT4) act via the TrkB receptor and sup

15 Brain-derived neurotrophic factor (BDNF) and neurotrophin-4/5 (NT4/5) exert their action through a co

16 rophic factor (BDNF), neurotrophin-3 (NT-3), neurotrophin-4/5 (NT4/5), ciliary neurotrophic factor, b

17 trkA), brain-derived neurotrophic factor and neurotrophin-4/5 (trkB), and neurotrophin-3 (trkC).

18 Neurotrophin-4/5 immunoreactivity was seen in small-(12-

19 ved neurotrophic factor, neurotrophin-3, and neurotrophin-4/5 were detected in 22, 9, and 19% of thes

20 eptor (brain-derived neurotrophic factor and neurotrophin-4/5) acutely sensitize nociceptive afferent

21 unoreactive for ciliary neurotrophic factor, neurotrophin-4/5, nerve growth factor, or VEGF.

22 ved neurotrophic factor, neurotrophin-3, and neurotrophin-4/5, showed that immunoreactive brain-deriv

23 nd truncated TrkB receptor, constitutive and neurotrophin-4/5-induced tyrosine phosphorylation was si

24 rotrophic factor, neurotrophin-3 (NT-3), and neurotrophin-4/5.

25 rotrophic factor (BDNF), neurotrophin-3, and neurotrophin-4/5.

26 d express decreased levels of mRNAs encoding neurotrophin-4 and glial cell line-derived neurotrophic

27 e receptor for neurotrophic factors BDNF and neurotrophin 4, and mediates their influence on neuronal

28 ived neurotrophic factor, neurotrophin 3 and neurotrophin 4, are survival factors for hES cells.

29 We report that neurotrophin-4 (but not NT3 or NGF), applied to embryoni

30 Sequestration of endogenous BDNF/neurotrophin 4 by intraspinal TrkB-Fc fusion protein adm

31 neurotrophic factor (BDNF), neurotrophin-3, neurotrophin-4, ciliary neurotrophic factor (CNTF), Axok

32 or for brain-derived neurotrophic factor and neurotrophin-4, has been implicated in regulating synaps

33 lia and overexpression of neurotrophin-3 and neurotrophin-4 in muscle did not cause hyperinnervation.

34 r synapses formed on myocytes overexpressing neurotrophin-4 (M+ synapses) exhibited a higher level of

35 ic factor (BDNF), neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4) activated the FL receptor, as dete

36 able to innervate taste buds is regulated by neurotrophin-4 (NT-4) and brain-derived neurotrophic fac

37 ated with the TrkB receptor ligands BDNF and neurotrophin-4 (NT-4) developed a full complement of Pur

38 brain-derived neurotrophic factor (BDNF) and neurotrophin-4 (NT-4) inhibit agrin-induced AChR cluster

39 el system of nerve-muscle coculture in which neurotrophin-4 (NT-4) is overexpressed in a subpopulatio

40 ration of the endogenous TrkB agonist ligand neurotrophin-4 (NT-4) profoundly decreases food intake a

41 ed that the levels of trkB mRNA and BDNF and neurotrophin-4 (NT-4) proteins are normal in the thalamu

42 hic factor (BDNF), neurotrophin-3 (NT-3), or neurotrophin-4 (NT-4) results in a 30-50% reduction in n

43 titutive secretory pathway without affecting neurotrophin-4 (NT-4) secretion.

44 , [125I]nerve growth factor (NGF), and [125I]neurotrophin-4 (NT-4) to perikarya in the ipsilateral no

45 Neurotrophin-4 (NT-4), a neuronal signaling molecule, is

46 rophic factor (BDNF), neurotrophin-3 (NT-3), neurotrophin-4 (NT-4), and glial cell line-derived neuro

47 rophic factor (GDNF), neurotrophin-3 (NT-3), neurotrophin-4 (NT-4), and their receptors because of th

48 rophic factor (BDNF), neurotrophin-3 (NT-3), neurotrophin-4 (NT-4), ciliary neuronotrophic factor (CN

49 hic factor (BDNF), neurotrophin-3 (NT-3), or neurotrophin-4 (NT-4), each at 100 ng/ml] showed a two-

50 e of BDNF and a related neurotrophin ligand, neurotrophin-4 (NT-4), in the regulation of revasculariz

51 rophic factor (BDNF), neurotrophin-3 (NT-3), neurotrophin-4 (NT-4), tyrosine kinase (trk) A, trkB, tr

52 single neurons, we determined that BDNF and neurotrophin-4 (NT-4), which both bind to the TrkB high-

53 To examine whether neurotrophin-4 (NT-4)-deficient mice, which have only 45

54 growth factor (NGF), neurotrophin-3 (NT-3), neurotrophin-4 (NT-4)].

55 The growth factors neurotrophin 4 (NT4) and brain-derived neurotrophic fact

56 that mRNA encoding TrkB and its two ligands, neurotrophin 4 (NT4) and brain-derived neurotrophic fact

57 Here, we discover that neurotrophin 4 (NT4) plays an essential role in mucus ov

58 ry axons in these animals was facilitated by neurotrophin 4 (NT4), because branching was virtually el

59 brain-derived neurotrophic factor (BDNF) or neurotrophin 4 (NT4), individually or together, are with

60 hic factor (BDNF), neurotrophin 3 (NT3), and neurotrophin 4 (NT4), is implicated in the physiology of

61 factor [(BDNF) alone or in combination with neurotrophin 4 (NT4)] increases the peak rate of develop

62 nd trkB mRNA expression were reduced whereas neurotrophin-4 (NT4) and trkC mRNA expression were incre

63 Brain-derived neurotrophic factor (BDNF) and neurotrophin-4 (NT4) are essential for the survival of g

64 brain-derived neurotrophic factor (BDNF) and neurotrophin-4 (NT4) have different developmental roles

65 We examined the learning and memory of neurotrophin-4 (NT4)-/- mice by using fear conditioning.

66 urotrophin (BDNF), neurotrophin-3 (NT3), and neurotrophin-4 (NT4)-and their receptors (NTrs) TrkA, Tr

67 roblast growth factor-4, CX3CL1/fractalkine, neurotrophin 4 oncostatin-M, pulmonary and activation-re

68 factor, but not ciliary neurotrophic factor, neurotrophin-4, or glial cell line-derived neurotrophic

69 derived neurotrophic factor, neurotrophin-3, neurotrophin-4, or glial-cell-line-derived neurotrophic

70 ion of brain-derived neurotrophic factor and neurotrophin-4, which, through the receptor p75, can kil