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1 the kinase-active Trk receptors and the p75 neurotrophin receptor.
2 ke receptor superfamilies, including the p75 neurotrophin receptor.
3 omponent of this receptor complex is the p75 neurotrophin receptor.
4 similar gamma-secretase cleavage is the p75 neurotrophin receptor.
5 receptor tyrosine kinases and the shared p75 neurotrophin receptor.
6 ate with the intracellular domain of the p75 neurotrophin receptor.
7 ota PKC.IRAK complex is recruited to the p75 neurotrophin receptor.
8 anism, supported by up-regulation of the p75 neurotrophin receptor.
9 actions of BDNF are mediated through the p75 neurotrophin receptor.
10 e induced by selective activation of the p75 neurotrophin receptor.
11 tracellular neurotrophin binding site of p75 neurotrophin receptor.
12 Schwann cell death via engagement of the p75 neurotrophin receptor.
13 or cell death decisions mediated by the p75 neurotrophin receptor.
14 f differentiation markers, and activation of neurotrophin receptors.
15 synthetic derivative LIGA20 activate various neurotrophin receptors.
16 small molecule agonists to transactivate Trk neurotrophin receptors.
17 S can physically associate with TrkA and p75 neurotrophin receptors.
18 least in part to differential trafficking of neurotrophin receptors.
19 of REM sleep by acting on one or more of the neurotrophin receptors.
23 udies provide a new reagent for altering p75 neurotrophin receptor actions after injury and suggest t
24 th factor (NGF) binding to both p75 and TrkA neurotrophin receptors activates the transcription facto
27 egulation of neurotrophins and their cognate neurotrophin receptors among other classes of transcript
28 ia the tyrosine receptor kinase B (TrkB)/p75 neurotrophin receptor and Fyn kinase in transfected cell
29 nteract through its TRAF domain with the p75 neurotrophin receptor and weakly with the lymphotoxin-be
31 receptor expression, p75(NTR) (low affinity neurotrophin receptor) and trkA (high affinity NGF recep
32 the cell death mediator p75(NTR) (the common neurotrophin receptor), and its interaction with proapop
33 or induced apoptosis in cells expressing p75 neurotrophin receptor, and enhances neurite outgrowth in
34 d trkC-IgG) were used to block activation of neurotrophin receptors, and AADH-CNTF was used to antago
35 was blocked by exposure to the high-affinity neurotrophin receptor antagonist K252a, or an antagonist
38 lipid rafts, little is known about how these neurotrophin receptors are directed there or how localiz
47 es binding of pro-nerve growth factor to p75 neurotrophin receptor, blocks pro-nerve growth factor in
48 growth factor (NGF) in complex with the p75 neurotrophin receptor but is distinct from that of micro
49 osteoprotegerin, FOXC2 and FOXF2, BMP-2, p75 neurotrophin receptor, caspase-11, guanylate-binding pro
50 library for genes affecting the dynamics of neurotrophin receptor-containing endosomes in motor neur
52 ssion of TrkC, a member of the Trk family of neurotrophin receptors, could drive tumorigenesis, invas
53 closely related to NRAGE, which mediates p75 neurotrophin receptor-dependent apoptosis, and necdin, w
54 of dynamin1 is a critical event coordinating neurotrophin receptor endocytosis and axonal growth.
55 kB (tropomyosin kinase receptor B), the main neurotrophin receptor expressed by neurons of the centra
56 lus propofol applications at the peak of p75 neurotrophin receptor expression after experimental trau
57 ricted to the developing nervous system when neurotrophin receptor expression peaks, indicate that BI
59 se is the lack of NO, which up-regulated p75 neurotrophin receptor expression, a receptor required fo
60 creased raft formation, neurotransmitter and neurotrophin receptor expression, NMDA- and BDNF-mediate
61 developmental-like programs and increase p75 neurotrophin receptor expression, probably to foster rep
63 tyrosine-related kinase B (TrkB) p75NTR (p75 neurotrophin receptor) facilitates stabilization of the
64 ceptor B (trkB) and a truncated form of this neurotrophin receptor, favoring the inactive form throug
65 hat Toll paralogs unrelated to the mammalian neurotrophin receptors function as neurotrophin receptor
66 S-HGGs, with recurrent fusions involving the neurotrophin receptor genes NTRK1, NTRK2 and NTRK3 in 40
69 tly, a closely related gene to p75NTR called neurotrophin receptor homolog-2 (NRH2) was identified; h
70 5 kDa neurotrophin receptor (p75NTR) and two neurotrophin receptor homologs (NRH1, NRH2) constitute a
72 ntrast, optical density for low-affinity p75 neurotrophin receptor immunoreactivity in the VLDB did n
74 myosin-related kinase B receptor (TrkB) is a neurotrophin receptor important for the synaptic plastic
79 We found that TrkB is the most prominent neurotrophin receptor in the mouse SVZ, but only the tru
80 ence for either ChAT or the low-affinity p75 neurotrophin receptor in the nucleus basalis Meynert fai
83 neurons that contain low- and high-affinity neurotrophin receptors in regions of the feline pons and
84 examined the expression of neurotrophins and neurotrophin receptors in the lesion/transplanted striat
85 -stimulating factor (M-CSF), the M-CSFR, and neurotrophin receptors in the NMDA-treated slices, as de
87 t-derived NGF promotes expression of the p75 neurotrophin receptor, in turn causing a reduction in th
89 functional interaction between TRAF6 and the neurotrophin receptor interacting factor (NRIF), two pro
95 aline residue at position 264 in the rat p75 neurotrophin receptor is necessary for the ability of p7
98 dings indicate that intracellular sorting of neurotrophin receptors is critical for postnatal neuroge
100 e tropomyosin-related kinase (Trk) family of neurotrophin receptors, is implicated in the growth and
103 y signals through the same Nogo receptor/p75 neurotrophin receptor/LINGO-1 (NgR1/p75/LINGO-1) complex
106 is and recent evidence suggests that the p75 neurotrophin receptor (NTR) contributes significantly to
108 while down-regulating the expression of p75 neurotrophin receptor (NTR), phospho-JNK, and Bcl-2-asso
109 rid library with the death domain of the p75 neurotrophin receptor (NTR), we identified the Sall2 tra
113 compound, EVT901, which interferes with p75 neurotrophin receptor oligomerization through direct int
115 tivity for pro-nerve growth factor (proNGF), neurotrophin receptor p75 (p75(NTR)), and sortilin in th
116 hese effects are mediated by presynaptic pan-neurotrophin receptor p75 (p75(NTR)), the pro-BDNF recep
124 lines of in vitro evidence suggest that the neurotrophin receptor p75 mediates or exacerbates Abeta-
126 induce apoptosis in neuronal cells, via the neurotrophin receptor p75(NTR) and the sortilin receptor
128 ed a marked upregulation of the proapoptotic neurotrophin receptor p75(NTR) in CA1, evident at 48 hr.
129 in PC-3 cells and siRNA directed against the neurotrophin receptor p75(NTR) in post-mitotic cultures
133 ases, may interact with the proapoptotic pan-neurotrophin receptor p75(NTR) to induce neuronal cytosk
134 kinase TrkA (also called NTRK1), the common neurotrophin receptor p75(NTR), and the proneurotrophin
135 how that the transmembrane domain of the pan-neurotrophin receptor p75(NTR), best known for regulatin
136 ability of SorCS2 to form complexes with the neurotrophin receptor p75(NTR), required for pro-brain-d
137 tion of saporin linked to an antibody to the neurotrophin receptor p75(NTR), which eliminates cells e
145 ll number and the number of cells expressing neurotrophin receptors p75(NGFR) and trkA were assessed.
146 d immunoprecipitation with antibodies to the neurotrophin receptors p75, trkA, trkB, and trkC showed
149 TAp73 is a transcriptional activator of p75 neurotrophin receptor (p75(NTR)) and that p75(NTR) mRNA
152 trophic factor (BDNF)-activated TrkB and p75 neurotrophin receptor (p75(NTR)) by disrupting the endos
153 ole in Alzheimer's disease (AD), and the p75 neurotrophin receptor (p75(NTR)) has been implicated in
161 rve growth factor (NGF) signaling by the p75 neurotrophin receptor (p75(NTR)) is critical for neurona
162 distinct structural determinants in the p75 neurotrophin receptor (p75(NTR)) is crucial for the iden
167 be initiated by activation of either the p75 neurotrophin receptor (p75(NTR)) or the more selective t
168 xes with LINGO-1 and either the low-affinity neurotrophin receptor (p75(NTR)) or TROY to initiate gro
171 ron loss, distal axonal degeneration and p75 neurotrophin receptor (p75(NTR)) upregulation in the per
172 uctures of complexes formed by the DD of p75 neurotrophin receptor (p75(NTR)) with RhoGDI, for activa
173 e de novo expression of the low-affinity p75 neurotrophin receptor (p75(NTR)), a gene that plays crit
176 mined the expression of the low affinity p75 neurotrophin receptor (p75(NTR)), an excellent marker of
177 This produced a substantial loss of both p75 neurotrophin receptor (p75(NTR))-positive and choline ac
182 receptor tyrosine kinases (Trk) and the pan-neurotrophin receptor (p75) to regulate complex developm
185 In recent studies, we have identified the neurotrophin receptor, p75(NTR), as a mediator of apopto
193 nase receptor TrkA, together with the common neurotrophin receptor p75NTR; both of which bind nerve g
194 neurotrophins bind with high affinity to p75 neurotrophin receptor (p75NTR) and lack the capacity to
198 t with antisense oligonucleotides to the p75 neurotrophin receptor (p75ntr) decreased basal survival
199 t of the sympathetic nervous system, the p75 neurotrophin receptor (p75NTR) has a dual function: prom
200 Here, we investigate the involvement of p75 neurotrophin receptor (p75NTR) in Abeta-treated human ne
202 ur goal was to determine the role of the p75 neurotrophin receptor (p75NTR) in the loss of islet symp
203 myelin-associated glycoprotein recruited p75 neurotrophin receptor (p75NTR) into a complex with LRP1
206 Immunocytochemistry for the p75 low affinity neurotrophin receptor (p75NTR) or for calcitonin gene-re
207 Plasticity was rescued by inhibiting p75 neurotrophin receptor (p75NTR) signaling or its downstre
210 drinking produces a mobilization of DLS p75 neurotrophin receptor (p75NTR), whose activities oppose
217 nchymal cells expressing both desmin and p75 neurotrophin receptor (p75NTR): HSCs in the liver parenc
218 ng cells (BTICs) and show that BTICs express neurotrophin receptors (p75NTR, TrkA, TrkB, and TrkC) an
219 rats by the recruitment of the low-affinity neurotrophin receptor, p75NTR, whose activities opposes
220 ed a mouse model with a mutation in the TrkA neurotrophin receptor (P782S) that results in reduced ub
222 same set of transcription factors from a p75 neurotrophin receptor peptide (p75NTRp)-tagged adenoviru
223 indicate that the ubiquitination of the TrkA neurotrophin receptor plays a critical role in NGF-media
226 fact that blockade of tyrosine kinase (Trk) neurotrophin receptors reduces basal GABRA4 promoter act
228 tyrosine receptor kinase A (TrkA) and TrkC, neurotrophin receptors required by DRG sensory neuron de
231 ng trkA, trkB, and trkC, the identity of the neurotrophin receptor(s) undergoing phosphorylation was
232 t of NRAGE, a MAGE protein that mediates p75 neurotrophin receptor signaling and neuronal apoptosis.
234 sults revealed new functions for proBDNF-p75 neurotrophin receptor signaling pathway in the control o
235 dopamine D1 receptors can be coupled to the neurotrophin receptor signaling to mediate the effects o
237 re, we demonstrate that EVT901 abrogates p75 neurotrophin receptor signalling by other ligands, such
240 cate that UCH-L1 is important for regulating neurotrophin receptor sorting to signaling endosomes and
241 gp120 were blocked by inhibitors of the p75 neurotrophin receptor, suggesting that proBDNF and gp120
242 hibition of the cell death domain of the p75 neurotrophin receptor (TAT-Pep5) and in mice lacking the
244 rocessing of synaptic vesicle components and neurotrophin receptors, the mechanism giving access to t
245 l and spatial protein expression patterns of neurotrophin receptors throughout the process of sensory
246 e, nicotinic acetylcholine receptor, and p75 neurotrophin receptor), thus demonstrating that pseudoty
247 dence for the CB1 receptor coupling the TrkB neurotrophin receptor to an axonal growth response in th
248 r-3 directly associates and recruits the p75 neurotrophin receptor to the axon-glial junction, formin
249 ility to redirect the apically localized P75 neurotrophin receptor to the basolateral membrane domain
251 hotyrosine immunoprecipitates identified the neurotrophin receptor TrkA (molecular weight approximate
254 that LRP1 activation could phosphorylate the neurotrophin receptor TrkA in PC12 cells and increase ne
255 on axonal transport of mitochondria and the neurotrophin receptor TrkA, cargoes that are critical fo
257 ss sensory neuron-associated markers such as neurotrophin receptors TrkA, TrkB, TrkC, and RET and the
260 rs of the neural crest and expression of the neurotrophin receptor TrkB and its ligand, brain-derived
261 endritically localized mRNA encoding for the neurotrophin receptor TrkB has important ramifications f
262 -ERK-CREB-BDNF pathway as pre-treatment with neurotrophin receptor TrkB inhibitor ANA-12 and MEK inhi
263 isual cortical neurons in young rodents, the neurotrophin receptor TrkB is associated with PSD-95.
264 is study, we show that the expression of the neurotrophin receptor TrkB is induced on astrocytes in w
271 om fresh human malignant gliomas express the neurotrophin receptors TrkB and TrkC, not TrkA, and they
274 ell surface signaling receptors, such as the neurotrophin receptor, TrkB, have emerged as potential t
276 ed inner ear sensory neurons fail to express neurotrophin receptors, TrkB and TrkC, suggesting that t
282 During retrograde signaling, endocytosed neurotrophin receptors (Trks) activate the extracellular
283 broblast growth factor receptors (FGFRs) and neurotrophin receptors (TRKs) through their N-terminal p
284 broblast growth factor receptors (FGFRs) and neurotrophin receptors (TRKs) to common signaling target
291 lesion formation, the neurotrophins and the neurotrophin receptor tyrosine kinases, trks B and C, ar
294 of neurons expressing specific high affinity neurotrophin receptors was determined immunohistochemica
295 assays with cysteine-rich domains-fused p75 neurotrophin receptor, we confirmed that EVT901 interfer
297 receptor agonist SKF38393, we found that Trk neurotrophin receptors were activated in embryonic day 1
298 involved in ectodomain shedding of p75NTR, a neurotrophin receptor with critical roles in neuronal di
299 and increasing the co-localisation of these neurotrophin receptors with retromer-associated sorting
300 -tagged raft-independent protein (the 75-kDa neurotrophin receptor; YFP-p75) was efficient even in th
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