ライフサイエンスコーパス: neurotrophin receptor p75

1 NgR1) and a signal transducing subunit (the neurotrophin receptor p75).

2 n and induce their death via cleavage of the neurotrophin receptor p75.

3 rats also differ in their expression of the neurotrophin receptor p75.

4 gested to be a death-inducing ligand for the neurotrophin receptor p75.

5 pressed mRNA or protein for the low-affinity neurotrophin receptor p75.

6 sine kinases, Trks, and the low affinity pan-neurotrophin receptor p75.

7 family of receptor tyrosine kinases and the neurotrophin receptor p75 [1].

8 The neurotrophin receptors p75 and trk were both present wit

9 of ER-alpha with the low- and high-affinity neurotrophin receptors, p75 and trkA, and with the choli

10 tyrosine kinase domain, and the low-affinity neurotrophin receptor p75 are expressed at low levels in

11 Immunolabel for the neurotrophin receptor p75, but not trkB or trkC, in the

12 The neurotrophin receptor p75 can induce apoptosis both in v

13 Activation of the neurotrophin receptor p75 has been shown to elicit oppos

14 Mice lacking the low-affinity neurotrophin receptor p75 have multiple peripheral neura

15 etyl transferase (ChAT) and the low-affinity neurotrophin receptor (p75) in both mass and clonal cult

16 The neurotrophin receptor p75 is a low-affinity receptor tha

17 NGF binding to the pan-neurotrophin receptor p75 is also involved but is not re

18 Efficient apical sorting of the neurotrophin receptor p75 is dependent on its O-glycosyl

19 The neurotrophin receptor p75 is induced by various injuries

20 that blocks the function of the low-affinity neurotrophin receptor (p75(LNTR)) prevented LIF-induced

21 lines of in vitro evidence suggest that the neurotrophin receptor p75 mediates or exacerbates Abeta-

22 ll number and the number of cells expressing neurotrophin receptors p75(NGFR) and trkA were assessed.

23 for choline acetyltransferase (ChAT) or p75-neurotrophin receptor (p75(NTR) ).

24 ProNGF activates p75 neurotrophin receptor (p75(NTR)) and sortilin receptors

25 TAp73 is a transcriptional activator of p75 neurotrophin receptor (p75(NTR)) and that p75(NTR) mRNA

26 (BDNF) activate two distinct receptors: p75 neurotrophin receptor (p75(NTR)) and TrkB.

27 The p75 neurotrophin receptor (p75(NTR)) belongs to the tumor ne

28 trophic factor (BDNF)-activated TrkB and p75 neurotrophin receptor (p75(NTR)) by disrupting the endos

29 ole in Alzheimer's disease (AD), and the p75 neurotrophin receptor (p75(NTR)) has been implicated in

30 The role of the p75 neurotrophin receptor (p75(NTR)) in adult cholinergic ba

31 Expression of the p75 neurotrophin receptor (p75(NTR)) in primary melanomas is

32 Here we report that the p75 neurotrophin receptor (p75(NTR)) is a co-receptor of NgR

33 We show that cleaved p75 neurotrophin receptor (p75(NTR)) is a component of the n

34 The p75 neurotrophin receptor (p75(NTR)) is a member of the tumo

35 The p75 neurotrophin receptor (p75(NTR)) is a multifunctional re

36 Here we show that the p75 neurotrophin receptor (p75(NTR)) is a regulator of gluco

37 rve growth factor (NGF) signaling by the p75 neurotrophin receptor (p75(NTR)) is critical for neurona

38 distinct structural determinants in the p75 neurotrophin receptor (p75(NTR)) is crucial for the iden

39 The p75 neurotrophin receptor (p75(NTR)) is expressed on many ce

40 The p75 neurotrophin receptor (p75(NTR)) is highly expressed in

41 The p75 neurotrophin receptor (p75(NTR)) mediates neuronal death

42 The p75 neurotrophin receptor (p75(NTR)) mediates the death of s

43 be initiated by activation of either the p75 neurotrophin receptor (p75(NTR)) or the more selective t

44 xes with LINGO-1 and either the low-affinity neurotrophin receptor (p75(NTR)) or TROY to initiate gro

45 The p75 neurotrophin receptor (p75(NTR)) regulates a wide range

46 Here, we show that p75 neurotrophin receptor (p75(NTR)) undergoes hypoxia-induc

47 ron loss, distal axonal degeneration and p75 neurotrophin receptor (p75(NTR)) upregulation in the per

48 uctures of complexes formed by the DD of p75 neurotrophin receptor (p75(NTR)) with RhoGDI, for activa

49 e de novo expression of the low-affinity p75 neurotrophin receptor (p75(NTR)), a gene that plays crit

50 The p75 neurotrophin receptor (p75(NTR)), a member of the tumor

51 Here, we report that the p75 neurotrophin receptor (p75(NTR)), a TNF receptor superfa

52 mined the expression of the low affinity p75 neurotrophin receptor (p75(NTR)), an excellent marker of

53 smic deletion mutant of the p75 low affinity neurotrophin receptor (p75(NTR)), indicating that this t

54 ferents, identified by the low-affinity, p75 neurotrophin receptor (p75(NTR)), with interneurons cont

55 This produced a substantial loss of both p75 neurotrophin receptor (p75(NTR))-positive and choline ac

56 GF, is a potent apoptotic ligand for the p75 neurotrophin receptor (p75(NTR))-sortilin complex.

57 ed synapse elimination via activation of p75 neurotrophin receptor (p75(NTR)).

58 prevented by blocking antibodies against p75 neurotrophin receptor (p75(NTR)).

59 aging in a complex with sortilin and the p75 neurotrophin receptor (p75(NTR)).

60 Levels of the pan-neurotrophin receptor p75(NTR) and the BDNF receptor Trk

61 induce apoptosis in neuronal cells, via the neurotrophin receptor p75(NTR) and the sortilin receptor

62 The neurotrophin receptor p75(NTR) has been implicated in me

63 ed a marked upregulation of the proapoptotic neurotrophin receptor p75(NTR) in CA1, evident at 48 hr.

64 in PC-3 cells and siRNA directed against the neurotrophin receptor p75(NTR) in post-mitotic cultures

65 work has demonstrated an involvement of the neurotrophin receptor p75(NTR) in this process.

66 rol process by the discovery that the common neurotrophin receptor p75(NTR) interacts in a ligand-dep

67 The neurotrophin receptor p75(NTR) negatively regulates spin

68 The pan-neurotrophin receptor p75(NTR) strongly inhibits activat

69 ases, may interact with the proapoptotic pan-neurotrophin receptor p75(NTR) to induce neuronal cytosk

70 kinase TrkA (also called NTRK1), the common neurotrophin receptor p75(NTR), and the proneurotrophin

71 how that the transmembrane domain of the pan-neurotrophin receptor p75(NTR), best known for regulatin

72 ability of SorCS2 to form complexes with the neurotrophin receptor p75(NTR), required for pro-brain-d

73 tion of saporin linked to an antibody to the neurotrophin receptor p75(NTR), which eliminates cells e

74 enomenon of pathological upregulation of pan-neurotrophin receptor p75(NTR).

75 ng with a signal-transducing coreceptor, the neurotrophin receptor p75(NTR).

76 rosine kinase receptors and the low-affinity neurotrophin receptor p75(NTR).

77 cetyltransferase (ChAT) and the low-affinity neurotrophin receptor, p75(NTR) .

78 hat neurotrophin binding to the low affinity neurotrophin receptor, p75(NTR), alone does not affect t

79 In recent studies, we have identified the neurotrophin receptor, p75(NTR), as a mediator of apopto

80 The common neurotrophin receptor, p75(NTR), has been shown to signa

81 Here we demonstrate that a second neurotrophin receptor, p75(NTR), is expressed by establi

82 ormation for apical sorting of transmembrane neurotrophin receptors (p75(NTR)) is localized to a juxt

83 g signals are generated by activation of p75 neurotrophin receptors (p75(NTR)).

84 MMPRIN), with the cognate apical marker, p75-neurotrophin receptor (p75-NTR).

85 unctionally blocking antibody toward the pan-neurotrophin receptor p75 (p75(NTR) ).

86 tivity for pro-nerve growth factor (proNGF), neurotrophin receptor p75 (p75(NTR)), and sortilin in th

87 hese effects are mediated by presynaptic pan-neurotrophin receptor p75 (p75(NTR)), the pro-BDNF recep

88 ceptors (tropomyosin-related kinase A [TrkA]/neurotrophin receptor p75 [p75(NTR)]).

89 The neurotrophin receptor p75 (p75NTR) is a receptor of Abet

90 receptor tyrosine kinases (Trk) and the pan-neurotrophin receptor (p75) to regulate complex developm

91 d immunoprecipitation with antibodies to the neurotrophin receptors p75, trkA, trkB, and trkC showed