ライフサイエンスコーパス: neurovascular unit

1 multiple cellular involvement affecting the neurovascular unit.

2 onal model of bidirectional signaling in the neurovascular unit.

3 ly escalating brain edema, and damage of the neurovascular unit.

4 y in neural/vascular interactions within the neurovascular unit.

5 within the central nervous system called the neurovascular unit.

6 pivotal role in dynamic signaling within the neurovascular unit.

7 is a downstream substrate of tPA within the neurovascular unit.

8 t the BBB and other nonneuronal cells of the neurovascular unit.

9 t regulate the formation and function of CNS neurovascular units.

10 ing molecules to improve the function of the neurovascular unit after injury.

11 TEMENT: Pericytes are a key component of the neurovascular unit and are essential for normal BBB func

12 Given the role of APOE in maintaining the neurovascular unit and as an anti-inflammatory molecule,

13 s support bidirectional signaling within the neurovascular unit and astrocytes as key modulators of P

14 ator (t-PA) can modulate permeability of the neurovascular unit and exacerbate injury in ischemic str

15 tion between different cell types within the neurovascular unit and intact blood-brain barrier (BBB)

16 e well established action of estrogen in the neurovascular unit and its potential interaction with re

17 ighly interactive processes that involve the neurovascular unit and neural stem cells.

18 phenotype, it plays a pathogenic role in the neurovascular unit and triggers neuronal hyperexcitabili

19 f SAC in functional preservation of ischemic neurovascular units and its therapeutic relevance in the

20 mmunication between the affected brain area, neurovascular unit, and peripheral immune cells.

21 ngers are effective in all cell types of the neurovascular unit, and should still be considered as a

22 etween neurons, vasculature, and glia within neurovascular units are critical for maintenance of the

23 Central nervous system (CNS) neurovascular units are multicellular complexes consisti

24 Neurovascular units are the cellular and molecular inter

25 They are positioned centrally in the neurovascular unit between endothelial cells, astrocytes

26 CNS pericytes are uniquely positioned in the neurovascular unit between endothelial cells, astrocytes

27 At the neurovascular unit, brain endothelial cells, astrocytes,

28 slowly, are prone to contamination by other neurovascular unit cells, and lose blood-brain barrier c

29 pelling evidence indicates impairment of all neurovascular unit components including the blood-brain

30 s well documented that all components of the neurovascular unit contribute to the restrictive nature

31 issue of the JCI points to perturbations of neurovascular unit coupling caused by perivascular macro

32 Understanding how the neurovascular unit develops and functions, and more spec

33 erived multipotent regenerative cells to the neurovascular unit during angiogenesis.

34 Intravenously injected DAG peptide homes to neurovascular unit endothelial cells and to reactive ast

35 e essential for maintaining integrity of the neurovascular unit following brain ischemia.

36 these various gene products normally control neurovascular unit formation and function will lend new

37 and neurovascular repair, and to protect the neurovascular unit from divergent inducers of injury and

38 f the interactions between components of the neurovascular unit has implications for various disorder

39 ese cells to the structural integrity of the neurovascular unit has not hitherto been assessed.

40 orably regulate multiple pathways within the neurovascular unit in non-neuronal cells and neurons dur

41 The exact role of pericytes in the neurovascular unit in the adult brain and during brain a

42 g depression susceptibility, implicating the neurovascular unit in the development of migraine aura.

43 s because of progressive degeneration of the neurovascular unit in the retina, a condition known as d

44 ay, we searched for molecular markers of the neurovascular unit, including endothelial cells and astr

45 The neurovascular unit is a coordinated and interactional sy

46 profoundly impacts communication within the neurovascular unit-neurons, astrocytes, and arterioles-c

47 Neurovascular unit (NVU) is a basic unit in the brain, i

48 ithin the greater context of a multicellular neurovascular unit (NVU) that includes neurons, astrocyt

49 Cerebral ischemia induces changes in the neurovascular unit (NVU) that result in brain edema.

50 Age-related changes to the neurovascular unit (NVU), and their consequences for cer

51 The concept of the neurovascular unit (NVU), formalized at the 2001 Stroke

52 in the regulation of the permeability of the neurovascular unit (NVU).

53 to be present in all major components of the neurovascular unit of both R6/2 mice and HD patients.

54 miR-155 is expressed at the neurovascular unit of individuals with MS and of mice wi

55 a series of structures collectively known as neurovascular units, or NVU, that are composed of endoth

56 al for the development and physiology of CNS neurovascular units, particularly in the brain.

57 Within the neurovascular unit, pericytes play important roles in re

58 hether activation of this pathway within the neurovascular unit protects the brain against blood-brai

59 Targeting the neurovascular unit should provide novel insights for eff

60 The concept of the neurovascular unit suggests that to be successful, strok

61 ailed model of potassium flow throughout the neurovascular unit (synaptic region, astrocytes, and art

62 astrocytes, and microglia, cell types in the neurovascular unit that can secrete MMPs.

63 contribution to cellular interactions at the neurovascular unit that influence the overall function o

64 Pericytes are uniquely positioned within the neurovascular unit to serve as vital integrators, coordi

65 totoxicity and increased permeability of the neurovascular unit with the development of cerebral edem

66 ons, the amacrine and horizontal cells, form neurovascular units with capillaries in 2 of the 3 retin

67 scular endothelial cells, which comprise the neurovascular unit within the central nervous system (CN