ライフサイエンスコーパス: nevi

1 in 44 AGMs from the Caribbean (St. Kitts and Nevis).

2 photoreceptor mosaic overlying the choroidal nevi.

3 y melanomas were associated with melanocytic nevi.

4 lysis to identify morphologically suspicious nevi.

5 lities in the retina overlying the choroidal nevi.

6 of keratinocyte dysplasia within dysplastic nevi.

7 stent on a cytomorphologic basis with occult nevi.

8 morphologic features of perianal melanocytic nevi.

9 compared with normal melanocytes and benign nevi.

10 toses; and malignant melanomas versus benign nevi.

11 teledermoscopy for short-term monitoring of nevi.

12 neous melanoma and is also commonly found in nevi.

13 fied, with the most common being intradermal nevi.

14 attern and dermal nests were associated with nevi.

15 short-term monitoring of clinically atypical nevi.

16 teledermoscopy for short-term monitoring of nevi.

17 noma, but only after stable growth arrest as nevi.

18 again was higher than that in normal skin or nevi.

19 so suggest a potential hormonal influence on nevi.

20 cancer according to the number of cutaneous nevi.

21 introduced term "mosaic RASopathy" for these nevi.

22 74-4,649) per 100,000 women with "very many" nevi.

23 sequencing on five specimens of large-giant nevi.

24 CI, 8.82%-14.76%) for women with 15 or more nevi.

25 s that predisposes to the formation of Spitz nevi.

26 lanoma tissues compared with melanocytes and nevi.

27 unctival nevus represents 5% of conjunctival nevi.

28 cytes described herein are probably combined nevi.

29 replicating melanomas and abnormal or benign nevi.

30 while the lowest expression was observed in nevi.

31 he discovery of genetic alterations in Spitz nevi.

32 uently develop collagenous connective tissue nevi.

33 elanoma, multiple primary melanomas, or many nevi.

34 re derived directly from benign, melanocytic nevi.

35 nment that constrain proliferation of common nevi.

36 the current clinical evaluation of choroidal nevi.

37 21 (4.6%) were melanomas, and 4 (0.9%) were nevi.

38 ifference between DNs and common melanocytic nevi.

39 ere identified at both time points in all 44 nevi.

40 Indices corresponding to common nevi (0-1), dysplastic nevi (1-4), and melanoma (5-8) we

41 rresponding to common nevi (0-1), dysplastic nevi (1-4), and melanoma (5-8) were significantly differ

42 75 [1.14-6.64]; P = .02), with more than 100 nevi (1.63 [1.02-3.60]; P = .04), or with the diagnosis

43 (1 pingueculum, 1 dermolipoma, 2 melanocytic nevi, 1 melanoma).

44 multivariable-adjusted hazard ratio per five nevi, 1.09, 95% CI, 1.02-1.16 for ER+/progesterone recep

45 confidence interval [CI], 0.98-1.10 for 1-5 nevi; 1.15, 95% CI, 1.00-1.31 for 6-14 nevi, and 1.35, 9

46 Twenty-three lesions were excised (3 nevi, 10 melanomas, 5 squamous cell carcinoma, 2 lymphom

47 Most of the nevi (116 [95.9%]) enlarged at some point during sequent

48 Images from 7 nevi (14%) were suboptimal in quality.

49 Of dysplastic nevi, 196 of 580 (34%) showed a positive biopsy margin,

50 sk group 1 [>50 common and/or </= 3 atypical nevi], 2.75 [1.14-6.64]; P = .02), with more than 100 ne

51 psy-proven lesions, including 55 melanocytic nevi, 20 melanomas, 15 basal cell carcinomas, 7 solar le

52 c nevi (67%) compared with 2 of 9 amelanotic nevi (22%).

53 c nevi (78%) compared with 6 of 21 melanotic nevi (29%), and was not significantly related to tumor t

54 8; 95% CI, 1.1-3.1); and at least 4 atypical nevi 5 mm or greater in diameter (OR, 1.9; 95% CI, 1.1-3

55 P = .05) more apparent in 14 of 21 melanotic nevi (67%) compared with 2 of 9 amelanotic nevi (22%).

56 nded bordering vessels were identified in 22 nevi (73%) and were significantly associated with the pr

57 f 477 lesions (119 melanomas [24.9%] and 358 nevi [75.1%]), which were divided into 12 image sets tha

58 reaction using a discovery set of 73 benign nevi, 76 primary cutaneous melanoma, and 11 in-transit m

59 (P = .02) more apparent in 7 of 9 amelanotic nevi (78%) compared with 6 of 21 melanotic nevi (29%), a

60 (34.5%+/-9.8%, P < 0.05) than in benign iris nevi (8.0%+/-1.4%) or normal irides (8.0%+/-1.2%).

61 3-11.01]; P < .01) and high nevi count (>200 nevi) (8.4 [2.14-33.19]; P < .01).

62 A convenience sample of 40 skin lesions (8 nevi, 8 seborrheic keratoses, 7 basal cell carcinomas, 7

63 contributed a total of 51 nevi, of which 44 nevi (86%) were used for the study.

64 82% (95% CI, 8.31%-9.33%) for women with 1-5 nevi, 9.75% (95% CI, 8.48%-11.11%) for women with 6-14 n

65 line to follow-up tissue anchors in 40 of 43 nevi (93%; P < .01) and 42 of 43 nevi (98%; P < .01), re

66 in 40 of 43 nevi (93%; P < .01) and 42 of 43 nevi (98%; P < .01), respectively.

67 tegies for diagnosis and management of Spitz nevi, a type of melanocytic neoplasm that most often dev

68 valence and morphologic features of perianal nevi according to race/ethnicity, sex, and age.

69 levels according to the number of cutaneous nevi among a subgroup of postmenopausal women without po

70 ociation of many total nevi (TN) or atypical nevi (AN) with tumor thickness.

71 explored the relationships between number of nevi and benign and malignant breast disease risk.

72 tive patient pathology samples of dysplastic nevi and cutaneous melanomas evaluated between September

73 of nevogenesis compared with common acquired nevi and differs from prior reports of BN development in

74 These results show that although melanocytic nevi and dysplastic nevi harbor stable genomes with rela

75 by the sudden onset of numerous melanocytic nevi and have been traditionally described in the settin

76 ose-response relationships between number of nevi and history of biopsy-confirmed BBD (n = 5,169; ptr

77 and increased nevi and V600K with increased nevi and less freckling (all P < 0.05).

78 component of structural damage in choroidal nevi and may correlate and possibly predict functional v

79 The mouse model also exhibited dermal nevi and melanocytic neoplasms of the central nervous sy

80 d additional regulatory loci and pathways in nevi and melanoma biology.

81 asive and metastatic melanoma, compared with nevi and melanoma in situ (P < 0.0001).

82 In large cohorts of nevi and melanoma samples, PDK1 expression was significa

83 MPM images corresponding to dysplastic nevi and melanoma were compared with standard histopatho

84 arrest and tumor suppression in melanocytic nevi and melanoma.

85 5 and p16 IHC analyses on a random series of nevi and melanomas.

86 ry melanoma, and almost completely absent in nevi and metastatic melanoma.

87 oliferations such as keratinocytic epidermal nevi and nevus sebaceous result from somatic mosaicism.

88 Most patients with melanoma had few nevi and no AN.

89 han lost, in primary melanomas compared with nevi and normal skin.

90 Similarly, microarray analyses of benign nevi and primary melanomas from different stages reveale

91 nuclear staining for both proteins in benign nevi and superficial spreading melanoma.

92 dings suggest associations between number of nevi and the risk of premenopausal breast cancer, BBD, a

93 roves our understanding of predisposition to nevi and their potential contribution to melanoma pathog

94 HRAS (GenBank 3265) (c.37G-->C) in the Spitz nevi and underlying nevus spilus.

95 r age, blond/light brown hair, and increased nevi and V600K with increased nevi and less freckling (a

96 Patients with many nevi and without previous melanomas or traits of familia

97 r 1-5 nevi; 1.15, 95% CI, 1.00-1.31 for 6-14 nevi, and 1.35, 95% CI, 1.04-1.74 for 15 or more nevi; p

98 % (95% CI, 8.48%-11.11%) for women with 6-14 nevi, and 11.4% (95% CI, 8.82%-14.76%) for women with 15

99 n of the nestin gene in melanoma compared to nevi, and 5-hmC binding in this region was significantly

100 family history, 59 years for those with many nevi, and 69 years for those with a previous melanoma).

101 nd tissues compared to human melanocytes and nevi, and AMIGO2 silencing in melanoma cells induces G1/

102 or benign iris lesions, including freckles, nevi, and an iris pigment epithelial (IPE) cyst, were im

103 genesis, benign "nevic" metastases, eruptive nevi, and epidermotropic metastatic melanoma.

104 unger age, blond/light brown hair, increased nevi, and less freckling, and NRAS(+) with older age rel

105 tion between malignant melanoma and atypical nevi, and may lead to a substantial reduction in the num

106 Analysis of 25 samples of normal human skin, nevi, and melanomas revealed a positive correlation betw

107 The majority of patients had fair skin, few nevi, and no history of melanoma.

108 ctive in many senescent human melanocytes in nevi, and this is linked to histological indicators of h

109 ly higher in primary melanoma, compared with nevi, and was further increased in metastatic melanoma.

110 Blue nevi are a clinically and pathologically heterogeneous g

111 Nevi are among the strongest risk factors for melanoma.

112 To test the hypothesis that nevi are associated with breast tumor risk, we explored

113 Spitz nevi are benign melanocytic proliferations that can some

114 Nevi are important phenotypic risk factors for melanoma

115 derately-to-severely and severely dysplastic nevi are more often associated with melanoma, and excisi

116 fferences between DNs and common melanocytic nevi are not completely understood.

117 sclerosis complex-related connective tissue nevi are not limited to the lower back, and occasionally

118 ow-up is mandatory, especially when multiple nevi are present and these drugs are used in an adjuvant

119 Cutaneous nevi are suggested to be hormone-related.

120 nt hypopigmented scars at surgical sites and nevi arising early in childhood.

121 We report a case of agminated Spitz nevi arising in a nevus spilus and use exome sequencing

122 95.8%; 136 of 142) categorized typical Spitz nevi as benign.

123 The propensity to consider more or fewer nevi as having ugly duckling signs was independent of th

124 ligands were abundant in severely dysplastic nevi, as well as in primary and metastatic melanomas.

125 he development of skin hyperpigmentation and nevi, as well as melanoma formation with incomplete pene

126 The number of nevi-associated melanomas increased from 15.5% to 33.3%.

127 image in vivo and noninvasively melanocytic nevi at three different stages: common nevi without dysp

128 ivariable-adjusted odds ratio for every five nevi attenuated from 1.25 (95% CI, 0.89-1.74) to 1.16 (9

129 nd invasive melanoma, dysplastic nevi, Spitz nevi, atypical nevus syndrome, family history of melanom

130 ation from 1991 to 2013 to characterize blue nevi (BN) by patient age at biopsy, location, self-repor

131 mutants were significantly younger, had more nevi but fewer actinic keratoses, were more likely to re

132 = 1.64; 95% confidence interval = 1.18-2.28) nevi but not 2-mm nevi (odds ratio = 1.06; 95% confidenc

133 tes growth arrest of Braf(V600E) melanocytic nevi, but is insufficient for complete progression to me

134 ng increased the identification of choroidal nevi by 27% (406 eyes [5.3%] by NMFP vs 545 eyes [6.9%]

135 abeled UDN and as morphologically suspicious nevi by the 9 dermatologists.

136 ive genes between DNs and common melanocytic nevi by three independent statistical approaches and its

137 s, are distinguished from common melanocytic nevi by variegation in pigmentation and clinical appeara

138 ement of clinically atypical nevi/dysplastic nevi (CAN/DN) is controversial, with few data to guide t

139 mostly asymptomatic, patients with choroidal nevi carry a moderate risk for malignant transformation

140 Most benign nevi carry oncogenic BRAF(V600E) mutations but rarely be

141 In dysplastic nevi cases, the rate of clinically significant change in

142 Congenital melanocytic nevi (CMN) and infantile hemangiomas are commonly encoun

143 Congenital melanocytic nevi (CMN) can be associated with neurological abnormali

144 d melanoma arising in congenital melanocytic nevi (CMN) is crucial, as patients with PNs most often e

145 mas (CMs), 3 melanomas arising in congenital nevi (CNMs), and 5 spitzoid melanomas (SMs), using vario

146 n was significantly increased in melanocytic nevi compared with melanomas (mean H scores, 254.8 versu

147 icopathologic diagnosis was made in 27.7% of nevi compared with only 10.3% using the standard method.

148 on-focused analyses were used, the number of nevi considered for biopsy was reduced by a factor of 6.

149 in MPM (4.5 [1.83-11.01]; P < .01) and high nevi count (>200 nevi) (8.4 [2.14-33.19]; P < .01).

150 risk, MITF p.E318K is associated with a high nevi count and could play a role in fast-growing melanom

151 in DNA methylomes associated with total body nevi count, incorporating genetic and transcriptomic var

152 The TAT for nevi decreased from 2 days to 1 day, for melanomas from

153 anocytic nevi involuted, while the remaining nevi did not change.

154 Nevi displaying a peripheral globular pattern enlarged s

155 Dysplastic nevi (DN) is a strong risk factor for cutaneous malignan

156 biopsy-proven, mild and moderate dysplastic nevi (DN).

157 Dysplastic nevi (DNs), also known as Clark's nevi or atypical moles

158 these distinctive neoplasms.Deep penetrating nevi (DPN) are unusual melanocytic neoplasms with unknow

159 The management of clinically atypical nevi/dysplastic nevi (CAN/DN) is controversial, with few

160 ickness or echographic features of choroidal nevi elevated up to 1.5 mm were recorded during the foll

161 were associated with prominent and atypical nevi elsewhere.

162 Eruptive melanocytic nevi (EMN) are characterized by the sudden onset of nume

163 Thirteen of the 14 clinically diagnosed nevi exhibited an IRA less than 150 gray-scale intensity

164 Of the 2089 clinical images of nevi from 80 patients (median number of nevi per patient

165 ch the problem of differentiating dysplastic nevi from common melanocytic nevi through a molecular le

166 An IRA of 150 gsi2 distinguished nevi from melanomas with a sensitivity of 0.89 and speci

167 typic profiles for epidermal and melanocytic nevi from recent studies.

168 es of melanocytic nevi (including dysplastic nevi) from melanoma, we sequenced exomes of melanocytic

169 n the top decile of the cohort or having any nevi greater than 5 mm in diameter.

170 Postmenopausal women with six or more nevi had a 45.5% higher level of free estradiol and a 47

171 cancer risk factors, women with "very many" nevi had a significantly higher breast cancer risk (HR =

172 omen with no nevi, women with more cutaneous nevi had higher risks of breast cancer (multivariable-ad

173 Nevi harbor some of the same oncogene mutations that als

174 hat although melanocytic nevi and dysplastic nevi harbor stable genomes with relatively few alteratio

175 Exome sequencing revealed that dysplastic nevi harbored a substantially lower mutational load than

176 n by BRAF(V600E)-activating mutations, while nevi harboring the same mutations have growth arrest.

177 enotypes including counts of common acquired nevi has not yet been established.

178 Because small-to-medium congenital nevi have a low risk of malignant transformation, total

179 While melanocytic nevi have been associated with genetic factors and child

180 n roughly 50% of melanomas and 70% of benign nevi, have improved response rates and survival in patie

181 omas according to patient risk factors: many nevi, history of previous melanoma, and family history o

182 ion-focused analysis and IPCA, and number of nevi identified for biopsy.

183 ls were recognized in over two thirds of the nevi imaged and were significantly associated with previ

184 eciation of intralesional details: Of the 30 nevi imaged, intralesional vessels were apparent in 30 (

185 examination revealed remnants of melanocytic nevi in 103 melanomas (54.2%).

186 ly suggested hypothesis regarding involuting nevi in BRAF inhibitor therapy is correct: Nevi that inv

187 a mutation carrier: total number of atypical nevi in childhood (hazard ratio [HR], 1.21; 95% CI, 1.02

188 nd a correlation between the distribution of nevi in childhood and adulthood and the distribution of

189 Numbers and distribution of melanocytic nevi in childhood are major indicators of the risk of me

190 observational cohort study from the Study of Nevi in Children was conducted from January 1, 2009, to

191 vey support conservative management of Spitz nevi in children, with clinical follow-up representing a

192 linic, University of Barcelona; and Study of Nevi in Children.

193 le phenotype, development of new melanocytic nevi in older individuals is uncommon and considered wor

194 tray the mutational repertoire of dysplastic nevi in patients with the dysplastic nevus syndrome and

195 histological appearance of connective tissue nevi in patients with TSC.

196 ence and morphologic features of melanocytic nevi in the perianal area.

197 derstanding the growth arrest of melanocytic nevi in vivo termed stable clonal expansion.

198 he method to distinguish between melanocytic nevi in vivo.

199 melanoma, we sequenced exomes of melanocytic nevi including dysplastic nevi (n = 19), followed by a t

200 Additionally, melanocytic nevi including dysplastic nevi showed a significantly lo

201 e the discriminatory profiles of melanocytic nevi (including dysplastic nevi) from melanoma, we seque

202 idence of moderately and severely dysplastic nevi increased from 1.0% to 7.2% and from 0.6% to 1.4%,

203 ely 50% of the existing acquired melanocytic nevi involuted, while the remaining nevi did not change.

204 rtance: The presence of numerous melanocytic nevi is a significant melanoma risk factor, but there ar

205 Monitoring of atypical nevi is an important step in early detection of melanoma

206 The progression of nevi is restrained by multiple tumor-suppressive mechani

207 sy-diagnosed mildly or moderately dysplastic nevi is unlikely to result in a clinically significant c

208 Number of nevi labeled UDN and morphologically suspicious nevi, sp

209 laser removal of tattoos, hidden suspicious nevi may be revealed gradually.

210 intrapatient comparative analysis (IPCA) of nevi may help improve the detection of melanoma.

211 ginning to understand the growth patterns of nevi may improve the ability of physicians to differenti

212 results suggest that the number of cutaneous nevi may reflect plasma hormone levels and predict breas

213 patient was 0.8 among the clinical images of nevi (mean, 1.0; range, 0.48-2.03) and 1.26 among the de

214 of PEDF in common and dysplastic melanocytic nevi, melanoma in situ, invasive melanoma, and metastati

215 We hypothesized that the number of cutaneous nevi might be a phenotypic marker of plasma hormone leve

216 mes of melanocytic nevi including dysplastic nevi (n = 19), followed by a targeted gene panel (785 ge

217 digital (n = 13) acral skin as well as acral nevi (n = 24) for clinical, histologic, and molecular fe

218 (785 genes) characterization of melanocytic nevi (n = 46) and primary melanomas (n = 42).

219 to discuss treatment options for melanocytic nevi, nevus sebaceus, port-wine stains, and hemangiomas.

220 sures were morphologic features of choroidal nevi obtained with SS-OCT imaging.

221 ence interval = 1.18-2.28) nevi but not 2-mm nevi (odds ratio = 1.06; 95% confidence interval = 0.92-

222 95% confidence interval = 0.92-1.21) or 5-mm nevi (odds ratio = 1.26; 95% confidence interval = 0.94-

223 The same 2089 digital images of the nevi of a sample of 80 patients (mean age, 42 years [ran

224 Perianal nevi of any size, at least 2 mm in diameter, and at leas

225 mimic an IPCA situation, with images of all nevi of each patient shown to the dermatologists, who we

226 riving mutations giving rise to melanomas or nevi of similar growth patterns.

227 [59%] were women) contributed a total of 51 nevi, of which 44 nevi (86%) were used for the study.

228 Patients with divided eyelid nevi often present for surgical management because of co

229 -1.44; P = .03), the nevus count of atypical nevi on the buttocks (HR, 14.00; 95% CI, 2.94-66.55; P =

230 s demonstrated that the presence of multiple nevi on the extremities conferred the highest relative r

231 linical characteristics of connective tissue nevi on the trunk and extremities of patients with tuber

232 Dysplastic nevi (DNs), also known as Clark's nevi or atypical moles, are distinguished from common me

233 nnually thereafter for moderately dysplastic nevi or atypical nevus syndrome; biannually for up to 3

234 on that can occur in the setting of eruptive nevi or epidermotropic melanoma metastases.

235 annually thereafter for severely dysplastic nevi or melanomas in situ; every 3 months for 2 years, b

236 quivocal in situ melanoma without associated nevi or regression was identified using a consecutive sa

237 : annually for mildly dysplastic nevi, Spitz nevi, or solely family history of melanoma; biannually f

238 free testosterone compared to those with no nevi (p for trend = 0.001 for both).

239 , and 1.35, 95% CI, 1.04-1.74 for 15 or more nevi; p for continuous trend = 0.003).

240 and 766 dermoscopic images (median number of nevi per patient, 19 [range, 8-81]), all melanomas were

241 s of nevi from 80 patients (median number of nevi per patient, 26 [range, 8-81]) and 766 dermoscopic

242 ipheral rim of globules (peripheral globular nevi [PGN]) observed with dermoscopy are associated with

243 ons of phenotypic characteristics (freckles, nevi, phenotypic index) and MC1R status with incident am

244 Absence of back nevi, presence of many freckles, a sun-sensitive phenoty

245 phenotypic characteristics, absence of back nevi, presence of many freckles, and a sun-sensitive phe

246 melanoma risk among patients with congenital nevi, prospective trials are needed to more accurately a

247 In the multiple choice matching test (n = 43 nevi), readers were shown a tissue anchor in a baseline

248 (2) In the annotation test (n = 29 nevi), readers were shown a tissue anchor in a follow-up

249 h arrest can be overcome and how melanocytic nevi relate to melanoma are also considered.

250 d PTEN, were not found among any melanocytic nevi sequenced.

251 nally, melanocytic nevi including dysplastic nevi showed a significantly lower frequency and a differ

252 ls ranged from 2 to 13; the most common were nevi, skin type, freckle density, age, hair color, and s

253 i labeled UDN and morphologically suspicious nevi, specificity of lesion-focused analysis and IPCA, a

254 ed in situ and invasive melanoma, dysplastic nevi, Spitz nevi, atypical nevus syndrome, family histor

255 frequencies: annually for mildly dysplastic nevi, Spitz nevi, or solely family history of melanoma;

256 nt signaling in the formation of melanocytic nevi, suggesting that activated Wnt signaling may be syn

257 ffect of histologic subtype, age, dysplastic nevi syndrome, and associated cancers on mutation rate;

258 g nevi in BRAF inhibitor therapy is correct: Nevi that involute while a patient is undergoing BRAF V6

259 o characterize certain pigmented melanocytic nevi that may also fit this paradigm.

260 or older, with 1 or more clinically atypical nevi that required short-term monitoring and were access

261 CI, 1.3-3.9); atypical nevus pattern (>/=20 nevi that were >/=2 mm in diameter), plus at least 5 nev

262 t were >/=2 mm in diameter), plus at least 5 nevi that were 5 mm or greater in diameter (OR, 1.8; 95%

263 py are associated with enlarging melanocytic nevi, their actual growth dynamics remain unknown.

264 In 2 eyes with nevi there was no increased vascularity; in another, fin

265 ting dysplastic nevi from common melanocytic nevi through a molecular lens.

266 melanoma tissues, compared with melanocytic nevi tissues.

267 is known about the association of many total nevi (TN) or atypical nevi (AN) with tumor thickness.

268 creased from 3,749 per 100,000 women without nevi to 4,124 (95% CI = 3,674-4,649) per 100,000 women w

269 eased from 8.48% for women without cutaneous nevi to 8.82% (95% CI, 8.31%-9.33%) for women with 1-5 n

270 xpression levels of miR-579-3p decrease from nevi to stage III/IV melanoma samples and even further i

271 Choroidal nevi typically have overlying hypoautofluorescence from

272 ts, who were asked to identify ugly duckling nevi (UDN).

273 atients with a recent diagnosis of choroidal nevi underwent a novel adaptive optical assessment that

274 Nevi underwent standardized RCM imaging at baseline and

275 f our study include self-report of number of nevi using a qualitative scale, and self-reported histor

276 ing of microscopic structures in melanocytic nevi using RCM is feasible.

277 primary cutaneous melanomas and melanocytic nevi vary widely between 4% and 72%.

278 The number of cutaneous nevi was associated with increased risk of breast cancer

279 Number of nevi was collected at inclusion.

280 ased in patient melanoma samples compared to nevi, we investigated the effect of enhanced FOSL1 expre

281 Connective tissue nevi were categorized per anatomic location and size.

282 Phenotypical data on melanocytic nevi were collected from a random sample of 133 members

283 levance: In this study, perianal melanocytic nevi were common and were associated with prominent and

284 Among higher-risk patients, those with many nevi were more likely to have melanoma on the trunk (41%

285 In addition, numerous preexisting nevi were noted to fade in color on the dual regimen.

286 c; from each participant, 3 confirmed benign nevi were randomly selected from the upper and lower bac

287 limitations in this study are that cutaneous nevi were self-counted in our cohort and that the study

288 tus, diagnosis of melanoma, and excisions of nevi) were collected.

289 spite this, the vast majority of melanocytic nevi, which typically form as a result of BRAF(V600E)-ac

290 Importance: Although nevi with a peripheral rim of globules (peripheral globu

291 ep in melanoma progression from nonmalignant nevi with BRAF mutations.

292 l. provide evidence that multiple congenital nevi with central nervous system lesions are likely excl

293 , which typically lead to benign melanocytic nevi with characteristic histologic features.

294 is the association of pigmented melanocytic nevi with extra-cutaneous features, classically melanoti

295 Associations of number of nevi with personal history of benign breast disease (BBD

296 distinguishes between melanoma and atypical nevi with sensitivity of 100% and specificity of 90.9%.

297 Imaging of choroidal nevi with SS-OCT enables visualization of intralesional

298 nevi without dysplastic changes, dysplastic nevi with structural and architectural atypia, and melan

299 cytic nevi at three different stages: common nevi without dysplastic changes, dysplastic nevi with st

300 Compared to women with no nevi, women with more cutaneous nevi had higher risks of