ライフサイエンスコーパス: newly

1 The contribution of newly absorbed alpha-carotene to postprandial vitamin A

2 Given the vast array of newly acquired knowledge in the field and technological

3 Specifically, we highlight newly added leaves and branches in the genomic tree of b

4 Newly admitted critically ill patients, greater than or

5 atients with melanoma in a group of surgeons newly adopting the procedure.

6 lignment and tree estimation can incorporate newly annotated and publically available plastomes and c

7 his leads to multiple clonal lineages in the newly apomictic population, and thereby alleviates some

8 We also discuss newly appreciated pathways that modulate context-specifi

9 ssion levels, Btn2p and Cur1p eliminate most newly arising [URE3] variants but do not cure [PSI(+)],

10 ession, prior to proliferation, is common in newly arising T cells (so-called "recent thymic emigrant

11 ns in response to viral infections: it traps newly assembled enveloped virions at the plasma membrane

12 Newly available data on the spatial distribution of reta

13 e dominated by nitrogen loss processes using newly available marine oxidants.

14 iew recent discoveries and, by interrogating newly available plant genomes, we advance the story of s

15 They newly bridge homogeneous and heterogeneous catalyst desi

16 Initial screening of a series of over 50 newly characterized 2-aminopyrimidines with affinity for

17 The clinical relevance of the newly characterized AKT1 VNTR merits investigation.SIGNI

18 The newly clarified role of Bcl11b distinguishes discrete co

19 and related giant viruses are assembled by a newly conceived assembly pathway that initiates at a fiv

20 purpose was to evaluate previously used and newly constructed metrics of arterial hyperoxia and syst

21 A newly constructed university building was selected for t

22 The absolute configuration of the newly created chiral centers was definitively assigned f

23 ecko Gymnodactylus amarali between five such newly created islands and five nearby mainland sites loc

24 althy individuals, based on deviation from a newly defined healthy plane (HP).

25 This newly defined mechanism confers protection from autoimmu

26 Regions contributing to the newly defined networks are spatially variable across ind

27 Follicular regulatory T (TFR) cells are a newly defined regulatory T cell (Treg) subset that suppr

28 mmatory ILC responses can be suppressed by a newly defined subset of ILCs with regulatory function.

29 evelopment, focusing on the description of a newly-defined, five-stage model of biofilm development a

30 CLEM imaging revealed distinct pools of newly deposited viral proteins within endocytic and none

31 This newly described connection from the inferior colliculus

32 Eating at a later clock hour is a newly described risk factor for adverse metabolic health

33 f SFTSV infection and support the use of the newly described STAT2 KO hamster model for evaluation of

34 However, the role of the newly described water-conductive mammalian isoform AQP4e

35 This year's highlights include newly designed home and gateway pages; a new 'multi-regi

36 approved photosensitizing agents as well as newly designed nanophotosensitizers.

37 d subsequent spreading of MDRPa, including a newly designed shower drain, disinfecting siphons undern

38 al problems can eventually be solved through newly designed synthesis strategies (e.g. as accomplishe

39 STITCHER 2.0 is a newly designed web tool that automates the design of pri

40 ases in the numbers of clonotypes, including newly detected clones and a decline in overall T-cell cl

41 1 years +/- 18.1; range, 15-102 years) had a newly detected finding of ovarian cyst described in the

42 Numerous newly detected intermediates-many separated by as few as

43 The feature of our newly developed analytical methods that coupled sample p

44 cell-surface antigens by FACS analysis and a newly developed cell-based ELISA.

45 This reaction relies on a set of newly developed chiral quinolyl oxazoline ligands.

46 However, only this newly developed CLIA test showed high specificity and co

47 e from vegetables was calculated by use of a newly developed comprehensive database.

48 ted EBV mutant induces B cell lymphomas in a newly developed cord blood-humanized mouse model that al

49 hyl-3-ketoacyl-ACP intermediate, came from a newly developed coupled ketosynthase (KS)-ketoreductase

50 Based on this data, using a newly developed gfp reporter system we validate an Hfq-d

51 The newly developed GO/pPG/anti-MBP/anti-Tau nanoimmunosenso

52 For (13)C-enriched CO2 samples, a newly developed isotope ratio mid-infrared spectrometer

53 gene-specific small interfering RNAs, and a newly developed luciferase-based reporter system to quan

54 within the catchment were integrated into a newly developed metacommunity model, which includes ecol

55 The synthesis includes a newly developed method to generate the dihydrobenzodioxo

56 The reliability of the newly developed methodology for the determination of sta

57 Our newly developed MLVA-13Bc assay is a highly discriminato

58 To this end, we tested the effect of a newly developed molecule UBP684 on GluN1/GluN2A receptor

59 t advances in and utility and limitations of newly developed mouse and nonhuman primate models of ZIK

60 Here, we report a newly developed multi-functional ultrasonic micro-elasto

61 Here we use a newly developed numerical model, which fully couples veg

62 Genetic or chemical PIM inhibition with a newly developed pan-PIM inhibitor, SEL24-B489, induced R

63 Porous liquids are a newly developed porous material that combine unique flui

64 fect disorders are produced in one hour by a newly developed process of temperature-regulated rapid s

65 user-friendly interface for CIA function and newly developed search function Isotopic Pattern Algorit

66 We applied a newly developed sensitive nanoflow-nanospray mass spectr

67 Here we put forward a newly developed simulation environment ARACHNE: it enabl

68 combined high strength and translucency, the newly developed submicron grain-sized alumina may be con

69 Newly developed targeted therapy can exert off-target ef

70 Although newly developed tests seem more sensitive, high-quality

71 The analysis of the experimental data with a newly developed theoretical model allows us to quantify

72 The newly developed tight UF hollow fibers not only possess

73 Here, we use a newly developed, high-resolution (800 mum isotropic), qu

74 Using newly-developed methods sensitive to the full range of e

75 enotyping was established by combining eight newly-developed VNTRs with five published ones.

76 The role of temozolomide chemotherapy in newly diagnosed 1p/19q non-co-deleted anaplastic gliomas

77 the treatment of standard-risk patients with newly diagnosed acute promyelocytic leukemia (APL).

78 ed patients from 18 hospitals in the UK with newly diagnosed advanced or metastatic colorectal cancer

79 observational cohort study of patients with newly diagnosed ALL, comparing prospectively collected i

80 e tool for the work-up of patients with both newly diagnosed and relapsed or refractory multiple myel

81 se, which includes more than 70% of patients newly diagnosed as having cancer in the United States.

82 Patients newly diagnosed as having cT1-2 N1-2b pathologically con

83 We retrospectively analyzed 783 AL patients newly diagnosed at our center between 2002 and 2016.

84 Patients with newly diagnosed brain metastases without prior local the

85 of index and secondary cancers in women with newly diagnosed breast cancer by using histologic or ima

86 age diagnosis among nonelderly patients with newly diagnosed cancer after the Affordable Care Act (AC

87 Eligible participants aged 1-18 years with newly diagnosed cancer and normal audiometry were random

88 ent uninsured among nonelderly patients with newly diagnosed cancer declined substantially after the

89 ood samples were obtained from patients with newly diagnosed cardiomyopathy and clinical suspicion of

90 e rare in adults, AMKL accounts for 4-15% of newly diagnosed childhood AML cases.

91 erences of survival rates and occurrences of newly diagnosed cryptococcosis between patients with and

92 d nurses in general practice associated with newly diagnosed dementia has not been subject to substan

93 udy examined youths 21 years or younger with newly diagnosed diabetes enrolled in a US managed care n

94 cing methods, have high diagnostic yields in newly diagnosed early-life epilepsies regardless of key

95 Approximately one-third of newly diagnosed epilepsy cases fail to become seizure-fr

96 ul as first-line monotherapy for adults with newly diagnosed epilepsy.

97 apy proved feasible in younger patients with newly diagnosed FLT3-mutated AML, but yielded no overall

98 Nine patients with newly diagnosed glioblastoma and four healthy volunteers

99 Eligible patients had newly diagnosed glioblastoma confirmed to express EGFRvI

100 tandard of care after biopsy or resection of newly diagnosed glioblastoma in patients up to 70 years

101 We assessed predictors of newly diagnosed HIV infections by comparing newly diagno

102 Rio de Janeiro and to identify predictors of newly diagnosed HIV infections.

103 ion, we prospectively enrolled patients with newly diagnosed HL (n = 19) and NHL (n = 2) onto the Ins

104 age-adjusted incidence rates for over 58,000 newly diagnosed melanomas.

105 l, phase 3 trial, we recruited patients with newly diagnosed multiple myeloma aged 18 years and older

106 INTERPRETATION: In patients with newly diagnosed myeloma, the addition of bortezomib to l

107 shown significant efficacy in the setting of newly diagnosed myeloma.

108 e is a reference treatment for patients with newly diagnosed myeloma.

109 on (ASCT) was investigated for patients with newly diagnosed myeloma.

110 vered a ZNF532-NUT translocation fusion in a newly diagnosed NMC patient.

111 mmune diabetes, and diabetes was reversed in newly diagnosed NOD mice.

112 ignificant survival benefit in patients with newly diagnosed non-co-deleted anaplastic glioma.

113 ersons with commercial health insurance with newly diagnosed OAG who underwent VF, FP, and OOI were 6

114 Six hundred seven patients with newly diagnosed open-angle glaucoma from the CIGTS.

115 study, we selected a cohort of patients with newly diagnosed or relapsed or refractory multiple myelo

116 mber 2013, 42,145 samples from patients with newly diagnosed or suspected lymphomas were reviewed, ac

117 INTERPRETATION: In newly diagnosed Parkinson's disease, the occurrence of c

118 212 newly diagnosed participants with PD were recruited into

119 Newly diagnosed patients should be counseled about avoid

120 f FDG-PET/CT scanning 12 weeks after CCRT in newly diagnosed patients with LAHNSCC (stage IVa/b) that

121 mographic, clinical, and laboratory data for newly diagnosed pediatric (age <15 years) TB cases repor

122 Newly diagnosed preschool children may have clinical and

123 aprostatic malignant lesion in patients with newly diagnosed prostate cancer.

124 /- standard deviation, 63 years +/- 17) with newly diagnosed pulmonary hypertension underwent cardiac

125 tratified random sample of 863 patients with newly diagnosed SCC of the oral cavity, oropharynx, lary

126 Tfh cells is increased both in children with newly diagnosed T1D and in autoantibody-positive at-risk

127 ) associated with the first MPH dose in boys newly diagnosed with ADHD predict MPH-associated changes

128 rst MPH dose to 40 stimulant drug-naive boys newly diagnosed with ADHD while they performed the AX ve

129 ing specialty and AF outcomes among patients newly diagnosed with AF.

130 to anti-multiple myeloma therapy in patients newly diagnosed with biclonal gammopathy multiple myelom

131 uring Your Health (MY-Health) study, persons newly diagnosed with cancer (prostate, colorectal, non-s

132 ence of sperm banking among adolescent males newly diagnosed with cancer and to identify factors asso

133 newly diagnosed HIV infections by comparing newly diagnosed with HIV-negative participants.

134 e CIS+ group, and exclusion of many patients newly diagnosed with HIV.

135 ntestinal epithelial cells (IEC) of children newly diagnosed with inflammatory bowel diseases (IBD) t

136 011 and 2013 cohorts, respectively; 92% were newly diagnosed with RR-TB (no prior RR-TB diagnoses).

137 paediatric patients aged 4-17 years who were newly diagnosed with ulcerative colitis.

138 randomised trial of patients of any age with newly diagnosed, histologically confirmed, squamous cell

139 lated to worse QOL and mood in patients with newly diagnosed, incurable cancer; however, the use of c

140 eterans Health Administration, patients with newly diagnosed, nonvalvular AF between 2004 and 2012 we

141 Patients with newly diagnosed, rifampicin-sensitive, previously untrea

142 to specialty care and treatment among those newly diagnosed.

143 We also find that the newly discovered A. vinelandii siderophore vibrioferrin

144 revalent in the injured axons, including the newly discovered alternative cleavage and polyadenylatio

145 The newly discovered cascade reaction showed excellent chemo

146 resentative sequences of both previously and newly discovered classes of riboswitches might reveal su

147 In this study, we present newly discovered fossil remains from intact archaeologic

148 nd kaumoebavirus.IMPORTANCE Pacmanvirus is a newly discovered icosahedral double-stranded DNA virus t

149 These newly discovered laws derive from the geometrical cell-m

150 The newly discovered locus may enhance understanding of the

151 These newly discovered MAGEA1-NICD1 and MAGEA1-FBXW7 interacti

152 The profile of 2 case patients infected with newly discovered OPXV, Akhmeta virus, exhibited antibody

153 Of the newly discovered PFASs found only in AFFF-impacted groun

154 reas alphaproteobacterial cyclases require a newly discovered protein that we term BciE, encoded by a

155 peatedly stray from, but then return to, the newly discovered resource.

156 results also help to refine the role of the newly discovered third divalent metal ion for DNA polyme

157 predicting sRNA-mRNA binding regions in two newly discovered, though uncharacterized, regulatory RNA

158 When validated on 99 newly-discovered genes with pathogenic mutations, the al

159 burs beta are expressed in larvae, pupae and newly emerged adults.

160 en, making it important to determine whether newly emerged pathogens cause sequelae.

161 ttle is known about the in vivo functions of newly emerging genes, especially in metazoans.

162 To investigate the newly emerging roles of lipopeptides, accurate measureme

163 promised population could be a reservoir for newly emerging strains.

164 des (e.g., size, area, and density); and the newly emerging theory suggesting that (1) both numerosit

165 cing lesions on T1-weighted MRI plus new and newly enlarged lesions on T2-weighted MRI]).

166 0, 3.2-7.9) and 88 (15%) versus 19 (3%) were newly enrolled in care (4.4, 2.6-7.4).

167 Using a newly established haploid biofilm model of C. albicans,

168 zed via singleplex allergy diagnostics and a newly established immunoblot diagnostic system.

169 , which was maintained by seven patients and newly established in an eighth patient at the end of 1 y

170 Newly evolved CREs are enriched in immune response and n

171 human transcription is more bidirectional at newly evolved enhancers and promoter regions.

172 The study of newly evolved genes has long fascinated biologists, but

173 g the data generated by NGS, the presence of newly evolved, yet known, strains of both CPV-2a and CPV

174 e or whether they arose independently across newly evolving land plant lineages has long been a matte

175 ouble strand breaks (DSB) and the joining of newly excised transposon ends with target DNA.

176 ipoprotein (LDL)/polysaccharide nanogels are newly explored as oral delivery systems with promising e

177 Newly formed black holes of stellar mass launch collimat

178 atment significantly improves the quality of newly formed bone by inhibiting BMP2 induced fatty cyst-

179 not host cells, contributed primarily to the newly formed bone.

180 About 50% of these newly formed bound residues contained one nitrogen atom

181 ted undesirable protein occlusion within the newly formed crystals.

182 involving CD200 ligand (CD200L) expressed by newly formed endothelial cells.

183 s are necessary to stabilize microtubules in newly formed high-order dendrites.

184 eric U(IV) might have become incorporated in newly formed iron precipitates.

185 regenerative mechanisms are very limited and newly formed neurons do not survive longer, probably due

186 Taken together, our findings suggest that newly formed prion oligomers are infectious.

187 an equatorial hydroxyl or amino group in the newly formed ring are considerably more active than thei

188 n by selectively eliminating and maintaining newly formed synapses via dendritic calcium spike-depend

189 on, and examine the relative contribution of newly formed versus existing tissue to segment formation

190 y acting as a pair of molecular scissors for newly formed vesicles originating from the plasma membra

191 orm their viral replication centers, and the newly formed virions are able to infect HeLa cells.

192 oprotein (GP1,2) antagonizes the trapping of newly formed virions at the plasma membrane by BST2, we

193 se of its stem-loop target RNA and extends a newly-formed alpha helix to the distal loop where it for

194 ages, actively differentiating myoblasts and newly forming myotubes.

195 TANGO1 remains at the neck of the newly forming transport carrier, which grows in size by

196 IL-37, a newly found anti-inflammatory cytokine of the IL-1 famil

197 provide proof-of-principle for the view that newly generated ASCs can acquire a mature PC phenotype t

198 t of dendrite arbors and dendritic spines in newly generated dentate gyrus granule cell neurons of th

199 ugh analysis of RNA-seq gene expression data newly generated for 448 cancer cell lines, combined with

200 This newly generated mouse serves as a tool to study the func

201 l location, we also found populations of non-newly generated neurons in several subcortical regions (

202 The newly generated oxidized proteoforms are shown to posses

203 ulti-drug-resistant HIV-1 variants, that the newly generated P2-Crwn-THF moiety confers highly desira

204 eny and diversification rate shifts using 31 newly generated transcriptomes and 88 other datasets cov

205 By analysing 92 newly generated viral genome sequences from blood donors

206 kNN-nearest and kNN-Kmeans, to partition the newly generated, attribute-enhanced graph.

207 The first signals sensed by newly germinating seeds - gravity and light - direct roo

208 have questioned the technical proficiency of newly graduating surgeons.

209 omposition, and mechanical properties of the newly grown layer were characterized.

210 P-20 to CS-AMEL hydrogel could reinforce the newly grown layer.

211 edicted for a bona fide AD, mutation of this newly identified AD reduced the efficiency of Rap1 bindi

212 Our results provide insight into a newly identified antiviral gene, as well as broadening o

213 ues were used to functionally characterize a newly identified branch of the UPR initiated by the ER-l

214 Among these human lncRNAs, 140 were newly identified by our study, and 246 were present in k

215 recover CD247, and thus TCR expression, in a newly identified CD247-deficient patient are described.

216 ved to negatively affect the recovery of the newly identified compounds.

217 KEY MESSAGE: Newly identified genes that are preferentially expressed

218 ctodermal cells as placode progenitors using newly identified genes upstream of the Six/Eya complex.

219 The newly identified governing mechanism of the substrate se

220 a CXXC type zinc finger, a PHD domain and a newly identified Heterochromatin Protein 1 (HP1) interac

221 framework for further functional analysis of newly identified IL-4-regulated proteins in B cells that

222 o characterize the functional effects of the newly identified mutations, and to assess genotype-pheno

223 A newly identified NB predicted to be specific for Pseudom

224 tion associated with increased expression of newly identified NEK6 transcriptional targets.

225 This direct interaction is mediated by the newly identified PALB2-interacting domain (PID) in RNF16

226 Data from the published literature and newly identified patients were gathered and analysed dur

227 Combined analysis of newly identified patients with NEFL-related CMT and all

228 oshadow domain interactions, we show using a newly identified peptide sequence from the Clr3 histone

229 lysine 2-hydroxyisobutyrylation (Khib) is a newly identified post-translational modification found i

230 These newly identified promoters are shown to be transcription

231 uter mitochondrial membrane are cleared by a newly identified quality control pathway involving the c

232 gulatory 3WJs generated in trans represent a newly identified regulatory category that we call struct

233 We also provide evidence of a newly identified regulatory pathway that could promote a

234 Here, we used a newly identified Sec61 blocker, mycolactone, to analyze

235 ed public health response to this relatively newly identified sexually transmitted infection.

236 Unlike the existing biomarkers, the newly identified signature also serves to distinguish in

237 firm that Rac1 binds to both sites, with the newly identified site having higher affinity and both si

238 biological function of Bcl7a and Bcl7b, two newly identified subunits of the SWI/SNF complex that ar

239 e predict the regulatory relationships among newly identified transcription factors and verify predic

240 2 immune responses is well established, the newly identified type 2 innate lymphoid cells (ILC2s) ca

241 GEF3, RAB21, ZFHX3, ENTPD6, ZFR2 and ZNF169) newly implicated in human obesity, 2 variants were in ge

242 nfarct size, and depressed cardiac function, newly implicating MerTK in cardiac repair after myocardi

243 These newly improved methods to the hydrogel process will allo

244 patients with germline mutations in these 4 newly included genes are lacking.

245 infection, including reactivation to produce newly infectious virus.

246 older patients whose primary care physician newly initiated an antidepressant for depression.

247 We compared HHF and death in patients newly initiated on any SGLT-2i versus other glucose-lowe

248 We distinguish impacts from newly installed sanitation systems (to achieve universal

249 ojected nutrient and electricity use through newly installed sanitation systems.

250 Arbequina oil and play an important role in newly introduced cultivars.

251 we present a mean field approximation of the newly introduced models.

252 fusion is functional in vivo and whether the newly introduced nonmuscle nuclei undergoes nuclear repr

253 Community diversity affects the survival of newly introduced species via resource competition.

254 alization magnitude-breadth distributions of newly isolated antibodies.

255 Newly isolated Enterococci faecalis bacterial strains AI

256 The newly isolated yeast strains were obtained by spontaneou

257 The current paradigm states that all newly made ILCs originate from common lymphoid progenito

258 the course of continuous growth, whereas the newly nucleated secondary small nuclei through a concent

259 -pregnant adults aged at least 18 years with newly or recently diagnosed HIV without a recent history

260 1a mutation led to increased straightness of newly polymerized MTs, and structural modeling data sugg

261 uveae showed diminution in 15 tumors (43%); newly present corectopia was observed in 6 patients (12%

262 incorporated into the initial evaluation of newly presenting early-life epilepsies and not just rese

263 ural stem cells that provide the majority of newly proliferated scar-forming astrocytes that protect

264 Watson and Puelles now newly propose that the mammalian ventral pallium gives r

265 Newly proposed biomarkers that target various stages in

266 Newly proposed candidate Zika virus vaccines might or mi

267 The proximity of the newly-recognised sandsheets to the palaeo-coastline of P

268 by the ectonucleotidases CD39 and CD73 is a newly recognized "immune checkpoint mediator" that inter

269 obvious in strains lacking polyphosphate, a newly recognized chemical chaperone.

270 logist-epidemiologist, identifying scores of newly recognized viruses from throughout the world and h

271 reased in response to IRI were predominantly newly recruited monocyte-derived inflammatory DCs.

272 nism for limiting the phlogistic activity of newly recruited monocytes.

273 inct pattern of genome rearrangements in the newly replicated region behind the stalled fork, which p

274 OB-folds are essential for the protection of newly replicated telomeres.

275 We have also observed that newly replicated viral DNA is not associated with cellul

276 The newly reported chemisorbed CO2 species at deltaC approxi

277 The newly reported equilibrium data also allow us to propose

278 scheme, we performed a cgMLST analysis of 92 newly sequenced genomes, plus an additional 142 strains

279 ble more accurate assembly and annotation of newly sequenced genomes.

280 lies of Rosales (outgroups), we analysed 130 newly sequenced plastomes together with 12 from GenBank

281 stepwise intramolecular heteroannulation of newly synthesized 4,5-substituted 3-amino- or 3-hydroxy

282 zed in the system, along with aggregation of newly synthesized AuNPs onto larger ones and their settl

283 A newly synthesized calix[4]pyrrole-based molecule is used

284 sis as well as to build plasma membranes for newly synthesized cells.

285 Here we show that a newly synthesized compound, L-HIPPO, captures the HIV-1

286 Then, the newly synthesized Daunorubicin is an inhibitor of neuron

287 prevents MRE11-dependent degradation of the newly synthesized DNA at stalled forks.

288 l analysis and numerical modeling that these newly synthesized doped CQWs are excellent candidates fo

289 Using a set of known and newly synthesized DYRK1A inhibitors, along with CRISPR-m

290 The acetylation of newly synthesized H4 occurs in the cytoplasm and the fun

291 This import involves binding of newly synthesized proteins by cytosolic peroxisomal biog

292 t mediates the co-translational targeting of newly synthesized proteins to cellular membranes.

293 sion was dependent on a continuous influx of newly synthesized PTC-containing mRNAs, indicating that

294 This study investigated if TTT-28, a newly synthesized thiazole-valine peptidomimetic, could

295 Biosynthetic sorting of newly synthesized transmembrane cargos to endosomes and

296 This technique can also be used to detect newly synthesized viral proteins.

297 Newly transcribed eukaryotic precursor messenger RNAs (p

298 exporter known to execute nuclear export of newly transcribed intron-containing pre-tRNAs.

299 ion systems (to achieve universal coverage), newly treated wastewater systems (to halve the proportio

300 This newly uncovered mechanism for Ca(2+) mobilization by bet