ライフサイエンスコーパス: newt

1 r mechanism of hair cell regeneration in the newt.

2 eld within the forelimb stump of red spotted newts.

3 s) to lens cells during lens regeneration in newts.

4 arget cells in the medulla of male roughskin newts.

5 rter snake populations coevolving with toxic newts.

6 NEWT is available at http://www.ebi.ac.uk/newt/.

7 The newt, a urodele amphibian, is able to repeatedly regener

8 in larvae, or on a novel one invented by the newt after metamorphosis.

9 ities of B approximately 10(-22) N. m(2) for newt and approximately 10(-23) N. m(2) for Xenopus chrom

10 In addition, newt and axolotl Tbx4 and Tbx5 expression is regulated d

11 nge, hydra, planarian, and salamander (i.e., newt and axolotl) species, but notably such regenerative

12 ee additional species (chick, Spanish ribbed newt and rainbow trout) reveals significant sequence ide

13 e chromophore and which differed between the newt and the bullfrog (lambda(max) = 430 nm) wild-type S

14 biological paradigm is that of the poisonous newt and the garter snake which has been studied extensi

15 This new strain (Portuguese newt and toad ranavirus - member of the CMTV clade) caus

16 asured in the range of 10(2) to 10(3) Pa for newt and Xenopus chromosomes.

17 gy term enrichment analyses for regenerating newt and zebrafish hearts revealed that distinct ECM com

18 e show here that, in two urodele amphibians, newts and axolotls, the regulation of Tbx4 and Tbx5 diff

19 Urodele amphibians (newts and salamanders) are of particular interest to the

20 Anuran (frog) tadpoles and urodeles (newts and salamanders) are the only vertebrates capable

21 nd in repetitive DNA from certain species of newts and schistosomes.

22 a role for ROS-production in neurogenesis in newts and suggest that this role may have been recruited

23 Experiments with regenerating limbs/fins in newts and zebrafish have shown that members of the Msx f

24 ke humans, certain adult vertebrates such as newts and zebrafish possess extraordinary abilities to f

25 on in other vertebrates such as salamanders, newts and zebrafish, where all healthy adults regenerate

26 somes isolated from cultured N. viridescens (newt) and Xenopus epithelial cells were measured by obse

27 ductive clasping (pre-copulatory mounting in newts), and paced mating (copulation rate as determined

28 imbs, we cloned Tbx4 and Tbx5 cDNAs from the newt, and generated antisera that recognize Tbx4 or Tbx5

29 response that occurs following amputation of newt appendages.

30 Newts are capable of regenerating several anatomical str

31 ot understood, but proximodistal identity in newt blastemal cells may be respecified by signaling thr

32 for Prod 1 and a growth factor for cultured newt blastemal cells.

33 This immunocytochemical study of the newt brain reveals AR-ir and ER-ir cells in several regi

34 n oxygen tension lead to events in the adult newt brain that share features with processes occurring

35 distribution of AR-ir and ER-ir cells in the newt brain, in general, is consistent with previous stud

36 e feature of limb regeneration in the larval newt, but this changes abruptly after metamorphosis so t

37 potential explanation for why zebrafish and newts, but not mammals, can regenerate their heart.

38 The Montseny brook newt (Calotriton arnoldi) has one of the smallest distri

39 component tenascin-C significantly increases newt cardiomyocyte cell cycle reentry in vitro.

40 First, we have cloned newt cDNAs encoding C3 and C5 and have generated Abs spe

41 is known of the molecular events that allow newt cells to transdifferentiate.

42 ve to the substrate, as has been reported in newt cells, whereas MTs in the cell body and in the retr

43 A similar bending rigidity was measured for newt chromosomes in vivo by observing bending fluctuatio

44 on the structure of single isolated mitotic newt chromosomes was studied using chromosome elastic re

45 rce-extension behavior of individual mitotic newt chromosomes was studied, using micropipette surgery

46 to completely disintegrate, single metaphase newt chromosomes.

47 Newt connective tissue growth factor, a secreted protein

48 We found that that local newts contain levels of TTX dangerous enough to dissuade

49 ments from the retina of the Japanese common newt, Cynops pyrrhogaster.

50 In the newt, deviation of nerves from the limb into the flank c

51 alysis, and DNA sequencing uncovered a novel newt differentiation-specific transcript encoding a skel

52 GFR-2 (KGFR and bek variants) and FGFR-3, in newts during lens regeneration.

53 Chromosome fibers isolated from newt erythrocytes also show a significantly reduced diam

54 Newt fibroblast growth factor (nFGF-1) is an approximate

55 ay represent the mammalian orthologue of the newt gene NvHBox-5.

56 This novel newt gene shares a conserved DNA-binding domain, the T-b

57 Using this approach, we have isolated a newt gene which in regenerating and developing limbs rev

58 We conclude that the newt has evolved novel strategies to secure its regenera

59 Adult urodele amphibians such as the newt have remarkable regenerative ability, and a critica

60 Newts have the remarkable ability to regenerate lost app

61 In the regenerating newt heart, we show dynamic spatial and temporal changes

62 venly distributed in the intact cells of the newt iris, with significantly higher levels of Prox 1 pr

63 Lens regeneration in the adult newt is a classic example of replacing a lost organ by t

64 NEWT is a new taxonomy portal to the SWISS-PROT protein

65 NEWT is available at http://www.ebi.ac.uk/newt/.

66 d whether such an exceptional ability of the newt is either attributed to a strategy, which controls

67 Lens regeneration in adult newts is a classic example of how cells can faithfully r

68 ly and mid-August corresponding to a peak in newt larval abundance.

69 ed Pol II axes, like those of the endogenous newt LBCs; as expected, they stained with antibodies aga

70 We show that expression of Pax-6 during newt lens regeneration coincides with cell proliferation

71 ressed in the dorsal and ventral iris during newt lens regeneration.

72 tone in somatic cells and its requirement in newt lens transdifferentiation and suggest that transdif

73 of RA receptors (RARs) are expressed in the newt limb and are thought to mediate the respecification

74 ed retroviruses to obtain stably transfected newt limb blastemal (progenitor) cells in culture which

75 ta suggest that MMPs are required for normal newt limb regeneration and that MMPs function, in part,

76 hat skeletal muscle dedifferentiation during newt limb regeneration depends on a programmed cell deat

77 elation with respect to Wnt signaling during newt limb regeneration.

78 Recent studies on the regenerating newt limb, using cells transfected with chimeric retinoi

79 M) caused separated centrosomes in metaphase newt lung cells to move toward one another with an avera

80 During metaphase and anaphase in newt lung cells, tubulin subunits within the kinetochore

81 Newt lung epithelial cell microtubules were visualized b

82 exhibited by microtubules (MTs) in migrating newt lung epithelial cells by time-lapse imaging of fluo

83 oscopy (FSM) of MTs and f-actin in migrating newt lung epithelial cells.

84 ion and suggest that transdifferentiation in newts might share common strategies with reprogramming a

85 anced migration and fragmentation of primary newt muscle cells.

86 Unlike mammalian myotubes, cultured newt myotubes are able to enter and traverse S phase, fo

87 ed with regeneration extract, whereas 25% of newt myotubes exhibited cell cycle reentry.

88 It induced newt myotubes to enter S phase in serum-free medium, and

89 Cultured newt myotubes were activated to enter S phase by purifie

90 Like their mammalian counterparts, newt myotubes were refractory to mitogenic growth factor

91 quently been identified in the genome of the newt (Notophthalamus viridescens), in schistosomes and i

92 During forelimb regeneration in the newt Notophthalmus viridescens, the dynamic expression o

93 enerating and nonregenerating limbs from the newt Notophthalmus viridescens.

94 C5, during limb and lens regeneration in the newt Notophthalmus viridescens.

95 us sperm heads were injected into GVs of the newt Notophthalmus, the resulting sperm LBCs displayed v

96 Isolated newt (Notophthalmus viridescens) chromosomes were studie

97 rey relationship between TTX-bearing Eastern Newts (Notophthalmus viridescens) and Eastern Hog-nosed

98 In this study the ability of the newt, Notophthalmus viridescens, to regenerate inner ear

99 volutionary arms race with their toxic prey, newts of the genus Taricha.

100 precisely such a cell surface component, the newt ortholog of mouse CD59.

101 e-directed mutants led to blue shifts of the newt pigment with five of them causing substantial shift

102 n the absorption maximum of the bullfrog and newt pigments, 44 nm.

103 nome and transcriptome of the Iberian ribbed newt Pleurodeles waltl, a tractable species suitable for

104 nhibition than rare bacteria in bullfrog and newt populations, in which Bd was prevalent (> 25%).

105 reaction was performed to amplify a partial newt Prox 1 sequence.

106 n against lethal Nav channel toxins (snakes, newts, pufferfish, insects), and in specialized habitats

107 rs, and that Eastern Hog-nosed Snakes within newt range are highly resistant to TTX.

108 Adult newts rapidly increased chemical defenses in response to

109 partial amino-acid sequences of the various newt RAR isoforms fused to a partial sequence of the thy

110 in a regenerated limb, whereas metamorphosed newts recruit muscle fibre cells in the stump for the sa

111 Newts regenerate lost limbs through a complex process in

112 amined the effect of an extract derived from newt regenerating limbs on terminally differentiated mou

113 mb regeneration occurs in anamniotes such as newts, salamanders, and zebrafish.

114 defense trait in North American and Eurasian newts (Salamandridae).

115 Using these newt-specific probes, we have found by in situ hybridiza

116 pected, they stained with antibodies against newt-specific proteins.

117 gene loss of function during regeneration in newts, specifically applied to lens regeneration.

118 f four amphibian species: bullfrogs, Eastern newts, spring peepers and American toads.

119 Here we report that the newt switches the cellular mechanism for limb regenerati

120 are the major cause of the red shift of the newt SWS2 pigment's spectrum.

121 nine vasotocin-like systems in the roughskin newt (Taricha granulosa).

122 ce and storage patterns in the rough-skinned newt (Taricha granulosa).

123 Frog (Pseudacris regilla) and the California Newt (Taricha torosa).

124 garter snakes to tetrodotoxin found in their newt (Taricha) prey.

125 An earlier study in rough-skinned newts (Taricha granulosa) indicated that the neuroanatom

126 In male roughskin newts (Taricha granulosa), AVT is an important facilitat

127 g populations of adult and larval California newts (Taricha torosa) to sustained stressful conditions

128 receptors in brains of adult male roughskin newts, Taricha granulosa, collected during the breeding

129 their femoral gland secretions, aquatic male newts that chemically attract females, and terrestrial s

130 d amplified a family of related genes in the newt; their different expression patterns in normal and

131 lack extended these classical experiments in newts to the now-standard amphibian model Xenopus laevis

132 ndance of adults and larvae of great crested newts (Triturus cristatus).

133 d microsatellite markers to show that female newts typically use sperm from 1-3 males under natural a

134 , but highly pathogenic for, salamanders and newts (Urodela).

135 We demonstrate that larval newts use stem/progenitor cells such as satellite cells

136 ndance of cultured bacteria on bullfrogs and newts was comprised of inhibitory bacteria, while only 2

137 Adult cardiomyocytes of zebrafish and newt, which are able to proliferate, maintain centrosome