ライフサイエンスコーパス: nexus

1 socio-ecological processes operating at the nexus.

2 the evolution of the agriculture-environment nexus.

3 amework for the study of data drawn from the nexus.

4 rk at the population-consumption-environment nexus.

5 , in part, controlled through a miR-31/FIH-1 nexus.

6 ion is the first identified outside the CCR5 nexus.

7 rtex region, an area that we term the dorsal nexus.

8 better understand the stakeholder-scientist nexus.

9 in-associated protein complex is a signaling nexus.

10 solic proteins, forming a protein complex or Nexus.

11 urce security in the food-energy-water (FEW) nexus.

12 hat meets these criteria, the Cancer RNA-Seq Nexus.

13 conomic activities, such as the water-energy nexus.

14 is a critical component of the water-energy nexus.

15 tand and leverage the water-energy-food-land nexus.

16 re research related to the electricity-water nexus.

17 few specific central intracellular signaling nexuses.

18 ral adhesion complexes known as gap junction nexuses.

19 s by addressing the humanitarian-development nexus; (3) remake, do not simply revise, leadership and

20 The energy-water nexus accounts for indirect resource consumption, includ

21 VFinder, cnvPartition, gain and loss of DNA, Nexus algorithms, PennCNV and QuantiSNP.

22 OAA WP-3D aircraft during the 2013 Southeast Nexus and 2015 Shale Oil and Natural Gas Nexus campaigns

23 ry for DNA cleavage and demonstrate that the nexus and hairpins are instrumental in defining orthogon

24 rking with the standard file formats Newick, NEXUS and phyloXML behind a consistent and simple API, p

25 with the phosphoinositide head group at its nexus and poised to interact with other proteins.

26 for agriculture within the scope of the FEW nexus and propose strategies for closing nutrient loops

27 eral controls on As cycling in the soil-rice nexus, and the sampling approach can be adopted for othe

28 otprints, planetary boundaries, human-nature nexuses, and telecoupling.

29 We show the bulge and nexus are necessary for DNA cleavage and demonstrate tha

30 We show that externalities at the nexus are not self-correcting in the marketplace.

31 These nexuses are intriguing because of their potential role i

32 sulting modifications implicate an ERK-Dicer nexus as a fundamental component of the oocyte-to-embryo

33 ion, which include the newly formed triazole nexus as a significant pharmacophore.

34 -derived T(H)1 and T(H)17 cells serve as the nexus between acute and chronic GVHD.

35 ms of these diseases or address the critical nexus between aging and disease.

36 reveals new roles for Ptch1 that lie at the nexus between BCC and SCC formation.

37 Here, we demonstrate that a tripartite nexus between Bcl-xL, cytoplasmic p53, and PUMA coordina

38 These data implicate Mcd1p as a nexus between cohesion and condensation.

39 Quantitative analysis of the nexus between deforestation and the emergence of Ebola v

40 pes positions the field of stem cells at the nexus between developmental biologists, who are fascinat

41 uld inform strategies to both understand the nexus between health and disease states of the respirato

42 f patients with familial PAH, but a possible nexus between increased inflammation and diminished BMP

43 Our previous studies revealed a nexus between metalloproteinases and prostanoids whereby

44 Nevertheless, a true nexus between microscopy and atomistic simulations is la

45 ateral and anterior thalamus may represent a nexus between mnemonic and control functions, such as ac

46 metabolic dysregulation in human BTICs to a nexus between MYC and de novo purine synthesis, mediatin

47 ved brain tumor-initiating cells (BTIC) to a nexus between MYC and mevalonate signaling, which can be

48 Thus, the SphK1/S1P/S1PR1 axis is at the nexus between NF-kappaB and STAT3 and connects chronic i

49 ulation and provide evidence for a conserved nexus between Nrps and this important developmental sign

50 t that mitochondrial dysfunction lies at the nexus between oxidative stress and the impaired diaphrag

51 In this study, we identified a critical nexus between p38MAPK signaling, and the transcription f

52 nstrate with a Prps2 knockout mouse that the nexus between protein and nucleotide biosynthesis contro

53 Together, our findings provide a nexus between reactive oxygen species homeostasis, auxin

54 signaling pathways and thereby function as a nexus between signaling and early endocytic trafficking.

55 ndings suggest that Fyn acts as a regulatory nexus between solar UV, ROS and signal transduction duri

56 G(1) to S phase of the cell cycle, is at the nexus between the cell cycle transcriptional program and

57 is a multifunctional kinase that serves as a nexus between the DNA damage response and the mitotic ex

58 regulatory targets of IFN and thus provide a nexus between the OsM and IFN pathways.

59 in the eukaryotic genome suggests a critical nexus between the regulatory potential of ncRNAs and the

60 y uncoupled, failing to provide an effective nexus between these two fundamental processes for carbon

61 The human model provides a nexus between these two universes, and recent studies ha

62 nous ligand, Ro60-associated ssRNA, forges a nexus between TLR ligation and fibrosis instigated by bi

63 This nexus between transcription and DNA topology promises to

64 urements were acquired during the California Nexus (CalNex) campaign in the Los Angeles basin in spri

65 ast Nexus and 2015 Shale Oil and Natural Gas Nexus campaigns.

66 ians recorded the presence or absence of the NEXUS Chest 7 clinical criteria (age >60 years, rapid de

67 We have validated the NEXUS Chest decision instrument, which may safely reduce

68 NEXUS Chest had a sensitivity of 98.8% (95% CI, 98.1%-99

69 We hypothesized that NEXUS Chest would have high sensitivity (>98%) for the p

70 our previously derived decision instrument (NEXUS Chest) for identification of blunt trauma patients

71 loped a robust ChIP-exo protocol called ChIP-nexus (chromatin immunoprecipitation experiments with nu

72 The NEXUS Class Library (NCL) is a collection of C++ classes

73 n each event converges at the temporospatial nexus commonly associated with the P3b component.

74 GalE pathway functions as a novel regulatory nexus connecting the UPR to the characteristic postprand

75 sights into how the RANKL/p38 MAPK signaling nexus controls gene expression in osteoclasts.

76 tiation, the Foxn1 pathway should serve as a nexus coordinating cell division, differentiation, and p

77 th both large collections of public ChIP-exo/nexus data and multiple, new ChIP-exo datasets from Esch

78 Because it acts as a signaling nexus, defects in ciliogenesis or cilial function cause

79 The dorsal nexus demonstrated dramatically increased depression-ass

80 ), and fly isolates in the Drosophila Genome Nexus (DGN).

81 opulation genomic studies (Drosophila Genome Nexus, DGN).

82 at brain network connectivity via the dorsal nexus (DN), a cortical area in the dorsomedial prefronta

83 By being positioned as the molecular nexus downstream of key oncogenic signaling pathways (e.

84 ly uncover a ROQUIN-AMPK metabolic signaling nexus essential for selectively promoting Tfh responses.

85 ChIP-exo/nexus experiments rely on innovative modifications of th

86 fired power plants during the 2013 Southeast Nexus field campaign provide a unique opportunity to eva

87 programmers to add the ability to interpret NEXUS files in newly developed software.

88 aR-/- mice implicated IFN-gamma as a crucial nexus for controlling PD-1-mediated tumor infiltration b

89 gs identify NHERF1 as an important signaling nexus for coordinating cell structure with metastatic be

90 GC box region but not the TRE, serving as a nexus for distal and proximal factors.

91 , indicating that CD44 signaling serves as a nexus for fate decisions regarding TR1 induction.

92 ociates with the core promoter and acts as a nexus for gene regulation through its interactions with

93 within promoter chromatin of SMC genes is a nexus for integrating signals that influence SMC differe

94 ll effector differentiation, and a role as a nexus for interactions with other effector systems, in p

95 ent a model that explains how RPS25 can be a nexus for multiple alternative translation initiation pa

96 neuronal extension and acts as a presynaptic nexus for multiple protein and proteoglycan interactions

97 or DNA polymerase, it could provide a robust nexus for nuclear control of mitochondrial genome copy n

98 These findings point to myocardin as a nexus for positive and negative regulation of smooth mus

99 in XRCC4 coincides with a sequence that is a nexus for radiation-induced regulatory events suggest th

100 l dynein molecules, and identify the IC as a nexus for regulatory interactions within the dynein comp

101 of the CMG helicase by Chk2 is an important nexus for response to DNA damage.

102 These findings suggest that PER3 may be a nexus for sleep and mood regulation while fine-tuning th

103 As a nexus for the actions of glucocorticoids and bipolar med

104 As a crucial nexus for the cell, mitochondria are involved in numerou

105 ward signaling, ACCg emerged as an important nexus for the computation of shared experience and socia

106 Each cortical area provides a nexus for the convergence of afferents and divergence of

107 nfected GC B cells as a potential pathogenic nexus for the development of the EBV-positive, GC-associ

108 As such, IDO-1 is a nexus for the induction of a key immunosuppressive mecha

109 P neurons, and that parietal cortex may be a nexus for the integration of visuospatial signals and mo

110 Spt5-like factors as evolutionary conserved nexus for the regulation and coordination of the machine

111 s) allows access to the active site and is a nexus for the regulation of transcription.

112 his indicates that LIP might be an important nexus for the transformation of visual direction selecti

113 summary, our study identifies MENA as novel nexus for the Wnt/beta-catenin and the Notch signalling

114 -localized NHERF scaffold proteins provide a nexus for tightly controlled PKD signaling via a PDZ dom

115 capacity for angioblast generation act as a nexus for vessel patterning.

116 tes (MCS) between organelles are proposed as nexuses for the exchange of lipids, small molecules, and

117 array of states that we term a "bifurcation nexus", for which we introduce a quantitative measure of

118 The NEXUS format allows different programs to share the same

119 cters, builds character matrices directly in NEXUS format and provides sequence randomization options

120 NCL available is to encourage the use of the NEXUS format by making it relatively easy for programmer

121 t the data file for each program, use of the NEXUS format prevents cut-and-paste errors as well as th

122 plify interpreting data files written in the NEXUS format used by many computer programs for phylogen

123 in phylogenetic four-state or binary data in NEXUS format, and output the corresponding bipartition s

124 read in an alignment in FASTA, ClustalW, or NEXUS format, compute a maximum weight matching, and exp

125 owsing and manipulation of character data in NEXUS format, well suited for use with alignments and tr

126 of Excellence (EuroFIR NoE; FP6) and EuroFIR Nexus (FP7) project paucity in food composition database

127 Our data suggest that a transport nexus from the intestinal lumen to the eggs introduces b

128 b database and analysis platform 'Gene Aging Nexus' (GAN) that is freely accessible to the research c

129 The drought-famine-starvation nexus has been the main, recurring, serious threat to he

130 This so-called "electricity-water nexus" has received increasing attention in recent years

131 Previous studies on the climate-water-energy nexus have primarily focused on mid- to end-century hori

132 The NEXUS Head CT DI assigned high-risk status to 420 of 420

133 ted a prospective observational study of the NEXUS Head CT DI in 4 hospital emergency departments bet

134 The NEXUS Head CT DI reliably identifies blunt trauma patien

135 alidation and comparison of the Canadian and NEXUS Head CT rules among the subgroup of patients meeti

136 l Emergency X-Radiography Utilization Study [NEXUS] Head CT decision instrument [DI]) can reliably id

137 eographic and population genetics analyses - NEXUS, IMa2 and Migrate.

138 h fills an important gap of the energy-water nexus in a residential unit and provides a decision maki

139 e most important feature of the energy-water nexus in China is the significantly uneven spatial distr

140 5-Hydroxymethylcytosine is a key nexus in demethylation that can either be passively depl

141 ally function as a crucial calcium-signaling nexus in hASCs during EFS.

142 port of splicing factors and the Tnpo3-CPSF6 nexus in HIV-1 biology.

143 on interfaces essential to Gbeta's role as a nexus in numerous signaling cascades.

144 These findings suggest that TBP could be a nexus in pathways that regulate cell proliferation and t

145 t of the recycling endosome, which acts as a nexus in the endo- and exocytotic networks.

146 opment budgets to address the poverty-health nexus in these settings.

147 YAP/TAZ is an important signaling nexus integrating diverse mechanical and biochemical sig

148 induced maturation protein-1 transcriptional nexus involved in long-term survival and function.

149 The water-energy nexus is of growing interest for researchers and policy

150 t a critical downstream link of the E1A-p400 nexus is the oncoprotein transcription factor c-Myc.

151 These findings reveal a neuroendocrine nexus linking olfactory sensation and reproduction in re

152 Thus, CDK2 serves as an important nexus linking primary beta-cell dysfunction to progressi

153 sues, it is possible that STIM1 represents a nexus linking protein O-GlcNAcylation with Ca(2+)-mediat

154 efore, the apelin/apelin receptor signalling nexus may operate as a paracrine signal that sustains tu

155 Using our recently developed ChIP-nexus method, we find that Pol II pausing inhibits new i

156 with DCs and that the GSL-CD169 recognition nexus might be a conserved viral mechanism of parasitiza

157 The Suc-Tre6P nexus model postulates that Tre6P is both a signal and n

158 This nexus model will allow us to optimize animal feed and hu

159 Pre-mRNA splicing is a complex regulatory nexus modulated by various trans-factors and their postt

160 The Fyn/Srcasm signaling nexus modulates activity of STAT3, PDK1, ERK1/2, Notch1,

161 tRNAs, nexus molecules between mRNAs and proteins, have a centr

162 contained a Membrane Occupation Recognition Nexus (MORN) motif found in the lipid kinase-phosphatidy

163 egion of Membrane Occupation and Recognition Nexus (MORN) motifs at the N terminus.

164 ossesses membrane occupation and recognition nexus (MORN) motifs, a structure shared with mammalian j

165 putative membrane occupation and recognition nexus motifs.

166 f biofuels on food security, the food-energy nexus needs to be investigated in the context of its lin

167 a broad range of phylogenetic data formats (NEXUS, Newick, PHYLIP, FASTA, NeXML, etc.), allow it to

168 pressing prolactin receptors (Prlr) form the nexus of a complex prolactin-responsive neural circuit,

169 In this manner, CA2 neurons form the nexus of a highly plastic disynaptic circuit linking the

170 romatin occupancy analyses place Klf6 at the nexus of a novel gp130-Klf-importin axis, which promotes

171 riments provide evidence that hnRNP K is the nexus of a novel post-transcriptional regulatory module

172 Thus, Grhl2 functions at the nexus of a novel regulatory network, connecting lung epi

173 nterposed between CA3 and CA1 that forms the nexus of a powerful disynaptic circuit linking EC input

174 a in Southwest Arabia in the Holocene at the nexus of a trading network that developed after ~3 ka be

175 the epidemiology and pathophysiology of the nexus of AF and type 2 diabetes.

176 ena, California during the California at the Nexus of Air Quality and Climate Change (CalNex) study.

177 MAP3K1 is therefore the nexus of an intracrine regulatory loop connecting the TG

178 The molecular machinery at the nexus of apoptosis and inflammation includes caspase-1 -

179 stablishes one molecule, CalDAG-GEFI, at the nexus of Ca(2+)-induced integrin activation, TxA(2) gene

180 We conclude that ZNF281 acts at a nexus of cardiac and inflammatory gene programs, which e

181 The primary cilium is a nexus of cell signaling, and ciliary dysfunction is asso

182 Thus, RTG2 lies at the nexus of cellular metabolism and genome stability, coord

183 This work describes an approach that is the nexus of chemical genomics and synthetic biology.

184 importance as sources of CO2 and an emerging nexus of climate mitigation initiatives, high-resolution

185 opography in cortical areas known to be at a nexus of cognitive, affective, and mnemonic processing.

186 interactions with the endothelium are at the nexus of complex, dynamic cellular and molecular network

187 scovery of an essential receptor pair at the nexus of conception provides opportunities for the ratio

188 The Brucella quorum sensing system is a nexus of control for several Brucella virulence factors

189 e formation of cilia, thereby operating at a nexus of critical cellular functions.

190 However, the factors at the nexus of DNA repair and chromatin modification/remodelin

191 The data suggest that LRRK2 acts at the nexus of dopamine and glutamate signaling in the adult s

192 This review describes the nexus of dramatic recent developments in optogenetic pro

193 Mitochondria are the nexus of energy metabolism, and consequently their dysfu

194 Despite being a nexus of eukaryotic gene regulation, the structure of th

195 One technology at the nexus of fluorescence-based screens is large particle fl

196 Pulmonary insufficiency is the nexus of late morbidity and mortality after transannular

197 ty and that sex differences are related to a nexus of marital experiences and associated health risks

198 Chiroptical effects at the nexus of mechanics, excitonics and plasmonics open new o

199 The nexus of metabolism relative to ecosystem productivity a

200 al proteins regulates migratory and invasive nexus of metastasizing tumor cells.

201 s a high-mobility group (HMG) protein at the nexus of mitochondrial DNA (mtDNA) replication, transcri

202 ormationally central role, the BG sit at the nexus of multiple anatomical 'loops' of synaptic project

203 s of key cancer-relevant molecules such as a nexus of multiple oncogenes and tumor suppressors.

204 A and its catestatin fragment may lie at the nexus of nicotinic cholinergic signaling in vivo.

205 t human c-MET and INK4a/ARF, situated at the nexus of pathways regulating myogenic growth and differe

206 , we demonstrate that the DN1(p)s lie at the nexus of PDF and photic signaling to produce appropriate

207 tamin D production, placing vitamin D at the nexus of phosphate homeostasis.

208 ning challenges and future prospects at this nexus of phylogenetics, population genetics, and genomic

209 g, and confirms the functions of Eps8 at the nexus of receptor signalling and vesicular trafficking.

210 on of myelinogenesis and acts as a molecular nexus of regulatory networks that account for the develo

211 ratory centers, and thus they serve as a key nexus of respiratory control.

212 d3-Dpb11 interaction has remained a critical nexus of S phase regulation through eukaryotic evolution

213 llic acid (GA) signaling and function at the nexus of several signaling pathways, are required for ar

214 These results place AKT at a nexus of signaling pathways whose proper activation has

215 distinct functions for primary cilia at the nexus of signaling, proliferation, and differentiation.

216 While the nexus of synthetic organic and physical-inorganic chemis

217 These findings provide the first tangible nexus of telomere biology with insulin resistance and ad

218 CD4(+) T cells are at the nexus of the innate and adaptive arms of the immune syst

219 These findings place Hand at a nexus of the transcriptional networks that govern cardio

220 The nexus of these five cell classes represents a functional

221 stributed set of processes and that BLA is a nexus of these multiple processes.

222 omboid protein Rbd2 functions in vivo at the nexus of three highly conserved processes: lipid regulat

223 and where matrix domains form trimers at the nexus of three neighbor hexamers.

224 this organelle has proven to be a veritable nexus of tightly regulated cell-signal reception between

225 locus on human chromosome 9p resides at the nexus of two critical cell cycle regulatory pathways, th

226 " functions of p53 appear to place it at the nexus of two opposing forces, cancer and aging.

227 Here we demonstrate that CK2 is at the nexus of two signaling pathways that protect tumor cells

228 There appears to be a nexus of USA300 community and hospital transmission netw

229 As such, fibrin(ogen) lies at the nexus of vascular injury and repair.

230 to one hypothesis, the VWFA develops at the nexus of visual inputs from retinotopic cortices and lin

231 Pnexus is freely available at http://www.snp-nexus.org.

232 tabase is freely available at http://www.snp-nexus.org.

233 n (Global And Restrained Docking Exploration Nexus), our benchmarked and server-ready flexible dockin

234 It suggests that the newly identified dorsal nexus plays a critical role in depressive symptomatology

235 ights the crucial role that the FM-TGF-beta1 nexus plays in fetal-type scarless skin repair.

236 in the central channel of nuclear pores, the nexus points of intermediate filament assembly, and the

237 educing increased connectivity of the dorsal nexus presents a potential therapeutic target.

238 gions are linked together through the dorsal nexus provides a potential mechanism to explain how symp

239 Nexus Rank and SNPRank have low specificity and high pow

240 Nexus Rank calls oversized CNVs.

241 om graph eigenmodes of network diffusion and nexus regions of white matter from edge density imaging,

242 a MORN (membrane occupation and recognition nexus) repeat-containing protein, protects axons from de

243 T cell AKT phosphorylation, a key signaling nexus required for T cell proliferation and expansion, t

244 This pathway may represent a signaling nexus required for the survival and growth of metastasiz

245 The water-energy nexus requires strategic and coordinated implementations

246 ty of 12.3% (95% CI: 11.6%-13.1%), while the NEXUS rule exhibited a specificity of 33.3% (95% CI: 32.

247 ity = 98.4%; 95% CI: 96.2%-99.5%), while the NEXUS rule identified 299 of these patients (sensitivity

248 The NEXUS rule, when applied to this same cohort, identified

249 the NOAA WP-3D aircraft during the Southeast Nexus (SENEX) 2013 field campaign.

250 We provide a program that will take data in Nexus sequential format, and directly output a set of in

251 cy and reshaping the embodied resource trade nexus should be addressed by considering the transfer of

252 the outcome of these trials could serve as a nexus; significantly increasing or dampening enthusiasm

253 ing a reducing agent-indicating gap junction nexus stability is modifiable.

254 loration of mechanisms by which gap junction nexus stability modulates intercellular communication.

255 in the p70S6K pathway and implicate PA as a nexus that brings together cell phospholipases and kinas

256 n the auditory thalamocortical system, a key nexus that combines, transforms, and distributes virtual

257 6) is located at the center of a topological nexus that connects many functional regions of the large

258 i5, NEDD4-1, and Mig6 form a novel molecular nexus that controls EGFR activation and downstream signa

259 that PIPKIgammai5 and SNX5 form a signaling nexus that controls EGFR endosomal sorting, degradation,

260 phosphate co-factors and a highly integrated nexus that converges on an unpredicted transient recepto

261 The common and necessary nexus that defines these 2 phenotypes is the presence of

262 thms in food intake and body weight and is a nexus that differentially regulates core temperature rhy

263 t and suggest that chromatin modifiers are a nexus that integrates differentiation and DNA replicatio

264 In combination, the PLCs act as a signaling nexus that integrates numerous signaling inputs, critica

265 eal a gut microbe-vascular microRNA-Sirtuin1 nexus that leads to endothelial dysfunction.

266 ParP serves as a critical nexus that regulates the localization dynamics of its ne

267 Thus, RalGDS forms a nexus that transduces growth factor signaling to both Ra

268 We suggest that APP acts as a signaling nexus that transduces information about a range of extra

269 nferior colliculus (IC), a midbrain auditory nexus, the effects of iontophoretically applied serotoni

270 xcept His317, which serves as an interaction nexus, these residues all lie on prominent loops within

271 nd that ATM or the Mre11 complex serves as a nexus to additional components of the pathway.

272 thways in HEK-hCaR cells and may represent a nexus to differentially regulate differentiation versus

273 Application of ChIP-nexus to four proteins--human TBP and Drosophila NFkB, T

274 suggests that TRIB2 functions as a signaling nexus to integrate the Wnt/beta-catenin, Hippo/YAP, and

275 ) is uniquely poised to serve as a strategic nexus to mechanistically control these behaviors.

276 th cell polarity Par proteins may serve as a nexus to transduce extracellular signals to transcriptio

277 We suggest that the Orai1 nexus transduces the STIM1-binding signal through a conf

278 Mutation of the nexus transforms Orai1 into a persistently open state ex

279 Using ChIP-nexus, we find that Hippo signaling keeps Ras targets in

280 constraints within the climate-energy-water nexus, we show that in the United States, over the cours

281 the importance of assessing the energy-water nexus when pursuing demand-side control targets or goals

282 The basal ganglia are a critical nexus where circuits necessary for the production of beh

283 sults suggest that Brm represents one of the nexus where diverse information of cell differentiation

284 reveals a nuclear phosphoinositide signaling nexus where PIPKIalpha, PI4,5P(2), and PKCdelta regulate

285 ; (2) that the reticular nucleus serves as a nexus, where several functionally related cortical areas

286 ChIP-nexus will be broadly applicable to the study of in vivo

287 essential Okp1 subunit is a multi-segmented nexus with distinct binding sites for Ame1, Nkp1-Nkp2 an

288 Specifically, it consists of 0D nexus with triple-degeneracy that interconnects 1D lines

289 We identify a critical 'nexus' within Orai1 connecting the peripheral C-terminal