ライフサイエンスコーパス: niche

1 ntal tolerances being met (i.e. the realized niche).

2 lity of the disease-associated hematopoietic niche.

3 or of living cells, an osmotically protected niche.

4 te-of-origin and suggesting a shared thermal niche.

5 SC) niche contain precursors that reform the niche.

6 ple, by depriving pathogens of a replication niche.

7 one of the key sources of CAFs in the tumor niche.

8 vanced microscopic imaging to elucidate that niche.

9 n establishing an F. nucleatum intracellular niche.

10 of nesting of cancer cell in the endothelial niche.

11 IV replication in this particular anatomical niche.

12 and thereby impairs proper lodgment into the niche.

13 sely resembles that of the adult spinal cord niche.

14 tiation to establish an epithelial stem cell niche.

15 ent understanding of the ureteric branch tip niche.

16 rive, including the formation of a stem cell niche.

17 central nervous system (CNS) called the NSC niche.

18 not a primary determinant of success in this niche.

19 ine Wnts emanating from the bone marrow (BM) niche.

20 nced their ability to colonize the stem cell niche.

21 regulates myeloid bias in an extramedullary niche.

22 erichia coli (UPEC) from their intracellular niche.

23 the recruitment and retention of APCs to the niche.

24 er than specific adaptations to a particular niche.

25 el-1 as a component and regulator of the HSC niche.

26 aled both common and unique features in milk niches.

27 tificial growth media that do not mimic host niches.

28 ng the establishment of vertebrate stem cell niches.

29 tight regulation in specific compartments or niches.

30 st avoid predation and compete for favorable niches.

31 es as tools in the exploration of ecological niches.

32 virophage genera occupy different ecological niches.

33 cting similar hierarchies in other stem cell niches.

34 volve new behaviours, and exploit ecological niches.

35 mammals to occupy relatively empty nocturnal niches.

36 m stimulation of endogenous neural precursor niches.

37 ession and signaling within the FL BM and LN niches.

38 attributed to adaptations to new ecological niches.

39 ls for live imaging of distal pre-metastatic niches.

40 jectories and limits on available ecological niches.

41 herapies are thought to reside in protective niches.

42 at may be conserved in other adult stem cell niches.

43 l aspects related to the human hematopoietic niche: (1) its anatomical structure, composition, and fu

44 o mucosal host defense of the nasopharyngeal niche, a reservoir for ME and upper respiratory infectio

45 mor cell niches compared to the perivascular niche across multiple regions in GBM patient tissue micr

46 adients, indicating divergence in ecological niche across the species' range.

47 that induces vascular sprouting, APC vessel niche affinity and APC vessel occupancy.

48 ression is induced in hematopoietic vascular niches after myelosuppressive injury.

49 pressing cancer cells served as a supportive niche also for coexisting IL-1beta-lacking cancer cells,

50 s long-range regionalized input to the V-SVZ niche and can regulate specific NSC subpopulations.

51 rrogating the complex composition of the HSC niche and dissecting the niche remodeling processes that

52 trol over the chemical and physical in vitro niche and enables identification of regulatory propertie

53 lar level to gain insights into a pathogen's niche and evolution and to characterize pathogen dispers

54 interplay between an animal's environmental niche and its behavior can influence the evolutionary fo

55 acteria, can vary based on the environmental niche and lifestyle of an organism.

56 rd ACh-NGF axis activates the gastric cancer niche and offers a compelling target for tumor treatment

57 functions in establishing the pre-metastatic niche and other aspects of metastasis.

58 purine nucleotides within the intracellular niche and relies on de novo purine synthesis to meet thi

59 ion and migration at the subventricular zone niche and results, for the first time, in NPC migration

60 n through the establishment of premetastatic niches and inhibit antitumor immune responses.

61 lacements on the shift into novel ecological niches and subsequent lineage diversification.

62 utant, cells proliferated in the BM survival niches and sustained long-term Ab titers.

63 ation of cells that form the progenitor cell niche, and abnormal proliferation of progenitor cells.

64 TEN-to-JAGGED-1 axis in maintaining the MaSC niche, and subsequently inhibiting breast cancer initiat

65 the hospital, most probably in the commensal niche, and that drug resistance is not a primary determi

66 ly active ('hot') in specific spatiotemporal niches, and the evolutionary selection of donor L1s driv

67 However, little is known about how those niches are formed.

68 Our analyses show that local environmental niches are highly phylogenetically labile for both seedl

69 hanisms that allow pathogens to target these niches are poorly understood.

70 rythrocytes provides a relatively protective niche as well as access to a rich source of nutrients.

71 distinct haematopoietic-supportive zebrafish niches, as well as with mammalian haematopoietic-support

72 Furthermore, major changes within the HSPC niche associated with previously described HSPC expansio

73 e ERA promotes the establishment of the stem niche at the bract axis but, after the reproductive tran

74 ion may have enabled species to expand their niches, becoming ecological generalists and dominating t

75 c regulator with an implication in stem cell niche biology.

76 und significant variation in niche position, niche breadth and interspecific niche overlap of these s

77 ibit the largest geographic distribution and niche breadth appear to be buffered the most from climat

78 revent insular animals from increasing their niche breadths even in the face of few competitors.

79 that island and mainland species had similar niche breadths.

80 as EphB2 was expressed in the center of pulp niches but not odontoblasts.

81 c nervous system regulate HSC egress via its niche, but how the brain communicates with the BM remain

82 NOD HSCs were held in their niche by excess expression of CXCR4, which, when blocked

83 We propose that the bone marrow niche can be altered by anticancer therapeutics, resulti

84 The mesenchymal alveolar niche cell is Wnt responsive, expresses Pdgfralpha, and

85 rupting pathways that maintain stem-like and niche cell phenotypes can translate into effective anti-

86 This article discusses the role of different niche cells and their stage- and disease-specific roles

87 The ability of stromal niche cells to control and adapt epithelial stem cell dy

88 ugh HSC adhesion to extracellular matrix and niche cells.

89 g distance from geographic range or climatic niche centre (distance-abundance relationships) remains

90 acute myeloid malignancies; (3) age-related niche changes and their suspected impact on hematopoiesi

91 ed RNAs) used for adaptation to the specific niches colonized by these bacteria (intestine, blood, or

92 Consequently, APC niche communication and retention are boosted by VEGF th

93 otein was highly expressed in the tumor cell niches compared to the perivascular niche across multipl

94 gressive overyielding suggests that positive niche complementarity effects are driving some of the re

95 s supplying the subependymal zone, acts as a niche component to sustain the neurogenic potential of a

96 ation's niches, we found strong evidence for niche conservatism during biological invasion.

97 Niche conservatism, i.e. the retention of a species' fun

98 In this study, we reveal that inflammatory niches consisting of tumor-associated macrophages and fi

99 g to particular social conditions) or social niche construction (i.e., individuals modifying the soci

100 Niche construction occurs when organisms modify their en

101 s are phenotypic (developmental) plasticity, niche construction theory, and epigenetics with transgen

102 onstrates the changing magnitude of cultural niche construction with varying human mobility and the e

103 ation, biogeochemistry, microbiome research, niche construction, and ecosystem engineering.

104 e results reveal a means of human biological niche construction, with phenotypic differences emerging

105 ristics of the hematopoietic stem cell (HSC) niche contain precursors that reform the niche.

106 and EGFR signaling by ROS levels in the PSC/niche controls lymph gland hematopoiesis under parasitis

107 owledge gained into leukemic stem cell (LSC) niche dependencies might be exploited to devise novel th

108 nverted into functional skin appendages in a niche-dependent manner.

109 vely denoted hereafter as FGRS) and vascular-niche-derived angiocrine factors.

110 ree provenances, reflecting a common thermal niche despite a 2,200 km geographic distance and 13 degr

111 understand whether both subspecies climatic niches differ from each other, what is the current poten

112 a fairly cryptic and fine-scale dimension of niche differentiation for coexisting tree species.

113 ght quantity and quality promotes ecological-niche differentiation of photosynthetic organisms.

114 ic and genomic diversity suggests ecological niche differentiation, but the selective forces influenc

115 and nucleic acids (DNA vs. RNA), suggesting niche differentiation.

116 This niche disruption could be recapitulated by overexpressin

117 rt in geographic space, resulting in greater niche divergence; (iv) ecotypes that currently exhibit t

118 suggested partial overlap of their temporal niches during crepuscular periods.

119 in the suboptimal environment outside their niches during invasion.

120 I examined the isotopic niche dynamics of four common sympatric desert mice (thr

121 ENM to understanding temporal dimensions of niche dynamics.

122 fects in human disease, this work shows that niche dysfunction may also cause disease, with possible

123 ote differentiation or disturb the stem cell niche effectively reduced tumor invasiveness and size, b

124 lizards that naturally partition the thermal niche, Elgaria multicarinata (southern alligator lizards

125 ation of a discrete JAG1(+) thymic medullary niche enriched for DC-lineage cells expressing Notch rec

126 out the body and sometimes take residence in niche environments with distinct communities of cells, e

127 Latil et al. (2017) show that the pre-tumor niche establishes a chromatin state predisposing squamou

128 d-wide invasion does not exhibit evidence of niche evolution.

129 ow remains vascularized and splenic vascular niches expand.

130 exhibit increased co-occurrence, mutualism, niche expansion, and hybridization - and rarely decline.

131 The liver provides a tolerogenic immune niche exploited by several highly prevalent pathogens as

132 crobia clades, occupying different energetic niches, express nitrous oxide reductase, potentially act

133 Manipulation of niche factors influencing the distribution and maintenan

134 ls are the major intestinal producers of the niche factors Wnt2b, Gremlin1, and R-spondin1, and are s

135 l dysfunction and oxidative stress trigger a niche favoring cholangiocellular overgrowth and tumorige

136 rom our sVAR model residuals, which suggests niche filtering.

137 further suggests a putative denitrifying PAO niche for Accumulibacter clade IA.

138 ression in osteoblasts to provide a survival niche for cancer cells.

139 ntation, partly by creating an SCF-dependent niche for follicular melanocytes.

140 served as a productive intracellular growth niche for L. monocytogenes.

141 of macrophages became necrotic, providing a niche for M. tuberculosis replication before escaping in

142 on fosters a permissive P-cadherin-dependent niche for MC transformation, invasion, and metastasis.

143 e efficient use of this tissue as an initial niche for subsequent vascular systemic dissemination of

144 ella serovar Typhimurium creates a favorable niche for this gut pathogen.

145 n-containing vacuoles (PVs) as intracellular niches for microbial growth.

146 ibition of CYP4A reduced lung pre-metastatic niche formation (evidenced by a decrease in vascular end

147 and mechanisms that govern adipose vascular niche formation and APC niche interaction are unknown.

148 gh) macrophages promoted lung pre-metastatic niche formation and metastasis.

149 y associated with metastasis, pre-metastatic niche formation and poor prognosis in breast cancer pati

150 ole for perivascular cells in pre-metastatic niche formation and uncovered novel strategies for limit

151 icroenvironment contributes to premetastatic niche formation at distant sites, but they also provide

152 ding important determinants of premetastatic niche formation.

153 l cells colonize and proliferate in distinct niches, from soil and plants to diverse tissues in human

154 gallery, and up to 11 eggs placed in lateral niches-from which emerge multi-instar larval tunnels tha

155 The subventricular zone neurogenic stem cell niche generates highly migratory neuroblasts that transi

156 Recently, another potential NSC niche has been identified in the filum terminale (FT), w

157 This thermally defined niche has promoted a range of adaptations both at the in

158 critical for parasite survival within these niches has largely depended on comparative transcriptomi

159 In addition, local tissue niches have age-specific influences on their resident st

160 l role for occluding-junctions in regulating niche-hematopoietic progenitor signalling and link this

161 olute and relative position of each species' niche in at least one isotopic axis.

162 found that the epidermis is a chemokine-high niche in both a mouse model and human vitiligo.

163 adaptation of S. aureus to the intracellular niche in human bronchial epithelial cells and in a murin

164 s a central role in regulating the stem cell niche in many organs, and thereby pivotally modulates de

165 d melanoma, and in ECs of the pre-metastatic niche in mice.

166 report a histological analysis of the FT NSC niche in postnatal rats and humans.

167 Our in vitro model might fill a vital niche in preeclampsia research.

168 lation mediating homing and retention to the niche in the bone marrow.

169 eated an abnormal perivascular proliferative niche in the cerebellum that persisted in adult animals

170 the concept that TNTs/TMs fill an important niche in the ever-changing microenvironment and the role

171 AF microvesicles and established stromal CSC niches in experimental and patient-derived breast cancer

172 parasites have to survive in many different niches in order to complete their life-cycles.

173 oduce exosomes that condition pre-metastatic niches in remote microenvironments to favor metastasis.

174 ins involved in establishment of plasma cell niches in sorted bone marrow and rectal cell populations

175 he retina, enabling them to occupy different niches in stimulus space.

176 poietic stem cells (HSCs) are mobilized from niches in the bone marrow (BM) to the blood circulation

177 and nitrogen, filling previously unassigned niches in the ocean.

178 Neural progenitors were organized in niches in the subependymal area and a decline in their n

179 oxic zone, suggests putative surface anoxic niches in these microbial mats.

180 mat depth will enable resolution of putative niches in these systems.

181 stly expanded the spatial and seasonal "fire niche" in the coterminous United States, accounting for

182 ose a risk for reinitiating infection within niches inaccessible to drugs, and tuning viral control o

183 cies distributed across different ecological niches, including human, animals, plants, and the enviro

184 e developed versatile strategies to generate niches inside the eukaryotic cells that allow them to su

185 ern adipose vascular niche formation and APC niche interaction are unknown.

186 To establish these replicative niches, intracellular pathogens secrete various virulenc

187 geographic range or centre of their climatic niche is a key assumption in many existing ecological hy

188 eukemia stem cells, WNT activation in the BM niche is also thought to contribute to the pathogenesis

189 The muscle stem cell niche is central for regulating the activation state of

190 mbly and maintenance of the adipose vascular niche is controlled by PPARgamma acting within APCs.

191 Thus, we show that WNT5A in the bone marrow niche is required to regenerate HSCs and leukemic cells

192 tains itself and remodels organelles in this niche is unknown.

193 Population variation in trophic niche is widespread among organisms and is of increasing

194 We find that common to all niches is the morning initiation of G1/S transition and

195 going efforts to develop new models to study niche-leukemic cell interaction in human myeloid maligna

196 strategies that aim at disrupting essential niche-LSC interactions or improve the regenerative abili

197 that promote adaptation to the genitourinary niche, making them gonococcus-like and distinguishing th

198 constrained by warm temperatures, so we used Niche Mapper, a mechanistic heat-balance model, to conve

199 base of bird nests, suggesting avian thermal niches might be broadly limited by temperatures during n

200 (c) Environmental niche model for the Sunda Islands clade of D. melanostic

201 Ecological niche modeling (ENM) has been used to address such quest

202 ed two methodological approaches (ecological niche modeling [ENM] and geometric morphometrics) to tes

203 tarity of population genetics and ecological niche modeling in understanding gene flow history.

204 Ecological niche modeling indicated that changing climate most like

205 Ecological niche modeling suggested that a gradual range expansion

206 ariation, phenotypic plasticity and climatic niche modeling to evaluate plant responses and elucidate

207 eas based on an ensemble of three ecological niche modelling methods, and evaluated the performance o

208 We coupled ecological niche modelling with simulations of potential dispersal

209 ta were compared with results from ecosystem niche modelling, and showed that 80% of tagged whale pos

210 We combined ecological niche models (ENMs) with population genetic simulations

211 s to projections from the empirical climatic niche models alone.

212 including multilocus DNA sequence, climatic niche models and chromosomal features.

213 of demographic models vs. simpler ecological niche models are still lacking owing to difficulties in

214 Ecological niche models calibrated with both native and pooled rang

215 Therefore, ecological niche models can provide a reasonable first approximatio

216 pes with projections from empirical climatic niche models for six tree species in northwestern North

217 hat should promote more realistic ecological niche models for transfer across space and time.

218 gical-niche-population models and ecological niche models in predicting documented shifts in the rang

219 Climate niche models project that subalpine forest ranges will e

220 Here, we show how extending successional niche models to include features common to all vegetatio

221 reveals the potential for empirical climatic niche models to over-predict suitable environmental spac

222 hrough the activity of an apical meristem (a niche of cells or a single cell).

223 is necessary for the formation of a pool or niche of osteoprogenitors that then contributes in a maj

224 y helping expand the geographic and seasonal niche of wildfire.

225 vision cycle (CDC) in 5 of the 16 neurogenic niches of adult brain, the dorsal telencephalon, habenul

226 xes the boundaries between the fluid dynamic niches of motile and non-motile phytoplankton, and highl

227 one of the main competitors of the temporal niches of the ancestral mammals, were found to be predom

228 in the constraint of conservative ecological niches, or if niche shifts occur at all commonly as part

229 EphA4 signaling that functions in stem cell niche organization and ultimately neuroblast migration i

230 rom Holocene baselines in terms of decreased niche overlap and in the absolute and relative position

231 he position, niche breadth and interspecific niche overlap of these species through time.

232 overlap with fundamental ideas in ecology on niche partitioning and limiting similarity between coexi

233 s would have fewer opportunities to climatic niche partitioning and other processes rather than envir

234 ined during the bloom, providing evidence of niche partitioning at the sub-clade level.

235 Despite this relatively apparent temporal niche partitioning between ancestral mammals and the rel

236 in regions with rainy summers where climatic niche partitioning is more likely.

237 structured by competitive interactions, with niche partitioning of food resources hypothesized to exp

238 ional drivers of species coexistence such as niche partitioning.

239 omparison of the skill of coupled ecological-niche-population models and ecological niche models in p

240 /or DE-Cadherin are reduced in NBs, NBs lose niche position and relocate to a non-native brain region

241 I found significant variation in niche position, niche breadth and interspecific niche ov

242 .e., individuals adjusting their behaviour), niche preference (i.e., individuals dispersing to partic

243 antify phylogenetic signals in environmental niche preferences and, especially, traits to help uncove

244 ry function in antimicrobial competition and niche protection.

245 on patterns of LN chains in the human limbal niche provided evidence for enrichment of LN-alpha2, -al

246 Their cellular microenvironment, called 'niche', regulates hematopoiesis both under homeostatic a

247 he constitutive cell cycle activity of these niches remains to be characterized in situ.

248 position of the HSC niche and dissecting the niche remodeling processes that appear to actively contr

249 s hitherto unknown Del-1 function in the HSC niche represents a juxtacrine homeostatic adaptation of

250 be relatively poor dispersers with specific niche requirements.

251 argo, thereby maximally exploiting potential niche resources.Bacteria can exchange nutrients and macr

252 ndins produced by (pre)osteoblasts in the BM niche, resulting in Wnt (co)receptor stabilization and a

253 Exposure of young HSCs to an OPN knockout niche results in a decrease in engraftment, an increase

254 The size of these self-assembled niches scaled with the density of cytokine-consuming cel

255 ing pathway as a key component of neurogenic niche sensing, contributing to the regulation of neural

256 d prey proxies, suggesting distinct seasonal niche separation.

257 These niches serve as sources of enteric neurotransmitters, su

258 We estimated dietary niche shift by comparing island species to their mainlan

259 and invaded areas is critical to identifying niche shifts during species invasion robustly, but also

260 int of conservative ecological niches, or if niche shifts occur at all commonly as part of the invasi

261 stromal cells to direct a hormone-responsive niche signaling program by activating expression of fact

262 It is unclear if stem cell niche signals coordinate fate decisions within the proge

263 During normal tissue repair, stromal niche signals, often Hedgehog-induced, promote epithelia

264 s without genetic information; (ii) tests of niche similarity revealed that three ecotypes, identifie

265 ffects, where early-arriving lineages occupy niche space via diversification and preclude dominance o

266 hs compete for the same scarce nutrients and niche space, and instead suggest that these organisms mo

267 more densely occupied regions of ecological niche space.

268 ogether these findings suggest that there is niche-specificity to the placental microbiota and placen

269 gating alleles, distributed as predicted for niche specifying genes, and the opportunity for host tra

270 in SIBER enabled us to estimate Hg isotopic niches, successfully discriminating several populations.

271 lity, and lower complexity relative to other niches, such as the gut.

272 The study of new environmental niches, such as the marine versus terrestrial subsurface

273 shes a unique lysosome-derived intracellular niche termed the Coxiella-containing vacuole (CCV).

274 an intracellular membrane-bound replicative niche termed the inclusion, which is enriched with bacte

275 troenteritis, mucosal inflammation creates a niche that favors the expansion of the pathogen populati

276 However, the niche that regulates follicular melanocytes is not well

277 ic inflammation generates a nutrient-replete niche that supports M. tuberculosis growth.

278 rees, with closely related species occupying niches that are no more similar than expected by random

279 s of clumps along the trait axis by creating niches that promoted the growth of species with specific

280 i.e. the retention of a species' fundamental niche through evolutionary time, is cornerstone for biol

281 oring cells in their organ-specific vascular niches through angiocrine factors, which include secrete

282 brain cell proliferation in most neurogenic niches throughout the forebrain and the midbrain.

283 enabling pneumococcal progression from this niche to cause invasive disease are poorly understood.

284 calize to the hair follicle stem cell (HFSC) niche to control HFSC-mediated hair regeneration.

285 e posterior signaling center (PSC) acts as a niche to regulate the hematopoietic response to immune s

286 sion patterns in the normal human colonic SC niche to understand how cancer stem cells (CSC) may aris

287 including cancer stem cells (CSCs), require niches to maintain stemness, yet it is unclear how CSCs

288 uire different types of supporting cells, or niches, to control stem cell maintenance and differentia

289 led early induction of distal pre-metastatic niches uncoupled from lymphangiogenesis at primary lesio

290 hin the 16 miRNA signature for the normal SC niche, we found that miR-206, miR-007-3, and miR-23b ind

291 change on the exotic wild boar population's niches, we found strong evidence for niche conservatism

292 These ecological niches were modeled using boosted regression trees and s

293 istal tip cell (DTC), the germline stem cell niche, where it negatively regulates a DAF-3 SMAD and DA

294 n the widths of hydrogen and oxygen isotopic niches (which estimate breadth of elevational range) and

295 d widths of the carbon and nitrogen isotopic niches (which estimates the diversity of resources consu

296 ronment is formed and establish complete HSC niches, which are functionally supportive of hematopoiet

297 Adult tissue stem cells (SCs) reside in niches, which, through intercellular contacts and signal

298 We investigated isotopic niche width in a small radiation of South American birds

299 Colonization niches with different magnesium concentrations influence

300 differentially influence distinct stem cell niches within a tissue.

301 ffects the formation of the larval stem cell niches, without altering other midgut cell types.