ライフサイエンスコーパス: nile red

1 marker phosphine 3R and the phospholipid dye nile red.

2 mutants stained with the lipid-sensitive dye Nile Red.

3 rticles encapsulating a model pharmaceutical Nile Red.

4 that modulates the fluorescent properties of Nile Red.

5 The lipid soluble fluorophore Nile Red (9-diethylamino-5-benzo[alpha]phenoxazinone) is

6 ionation in an electrospray plume containing Nile Red, a solvatochromic dye (i.e., a dye for which sp

7 The solvatochromic nature of Nile Red also offers the possibility of plastic categori

8 Nile red and a new silanized form of nile red that can b

9 er of targets, strong intrinsic quenching of Nile red and ANSA dye fluorescence is observed on bindin

10 Micelles loaded with the model drugs Nile red and DiO were used to demonstrate the ROS-depend

11 h the localized encapsulation of hydrophobic Nile red and hydrophilic calcein.

12 Nile Red and rhodamine 6G molecules prefer the environme

13 entified by staining with the lipophilic dye Nile red and the marker protein ADRP.

14 he bimolecular interaction between the probe Nile Red and the vesicle were evaluated from the uncorre

15 ng the diffusion rates of the dyes ethidium, Nile red, and eosin Y across the outer membrane, as well

16 ixed, stained with the fluorescent lipid dye Nile Red, and imaged by conventional confocal microscopy

17 tionary phase with a polarity-sensitive dye, Nile red, and optical sectioning with confocal microscop

18 of fluorescence using the hydrophobic probe, nile red, and the deposition of mature lamellar unit str

19 ed by encapsulation of the fluorescent probe Nile Red, and the micelle sizes were determined by dynam

20 micelles were preloaded with the model drug Nile red, and the resulting hydrogels demonstrated ROS-d

21 ed that CeO2 NPs and nanocapsules containing Nile red are able to traverse the chorion.

22 nd collisional flux onto the cell surface by Nile red are used to achieve single-molecule localizatio

23 stems for controlled release, the release of Nile Red as a "model payload" was examined.

24 Here we identify Nile red as a new fluorescent substrate for CaCdr1p, CaC

25 osed that the reformation of the fluorescent Nile Red becomes chemically "gated" in the organic phase

26 The Nile Red binding site is competitively eliminated by itr

27 gomers were more hydrophobic (as measured by Nile Red binding) and were highly toxic to neuronal cell

28 Together, the data suggest that Nile Red binds to the active site with high affinity ( a

29 Nile Red binds with apparent Kd values of 0.05 and 2.3 m

30 mpound 1 had three hydroxyl groups more than Nile Red, but was surprisingly insoluble in aqueous medi

31 This indicates that Nile red can be used for the identification of inhibitor

32 tent among different species, in contrast to Nile red cell staining procedures.

33 atography and mass spectrometry (GC-MS), and Nile red cell staining suffer drawbacks, including poor

34 mission compared to direct excitation of the nile red chromophore at 540 nm.

35 containing a two-photon absorbing dye and a nile red chromophore has been synthesized.

36 Nile Red (compound A) fluoresces at about 530 nm with go

37 vesicle radius distributions, and the linear Nile Red concentration dependence of the mean off-time.

38 a sigmoidal dependence of heme spin state on Nile Red concentration, where the first equivalent of Ni

39 s well as excited-state lifetimes at varying Nile Red concentrations, indicate a high-affinity site t

40 Oxidation-responsive release of encapsulated Nile Red demonstrates the potential of these micelles as

41 The hypothesis tested in this paper is that Nile Red derivatives that incorporate water-solubilizing

42 Thus three Nile Red derivatives, 1-3, were prepared.

43 The solvatochromic dye Nile Red dispersed in selected hydrogen bond acidic poly

44 rinsic fluorescence, and fluorescence of the Nile red dye bound to OCP.

45 d by imaging the fluorescence intensity from Nile red dye doped into suspended 1,2-diphytanoyl-sn-gly

46 put microplate assay was developed that uses Nile red dye to quantify neutral lipids that have been e

47 ontaining inorganic oxides as a quencher for Nile Red dye.

48 lipophilic dye-maleimide and the blocking of Nile red efflux by covalent labelling with bulky maleimi

49 fficiency, along with a 3.4-fold increase in nile red emission compared to direct excitation of the n

50 Surprisingly, both "free" and silicate-bound nile red exhibit relatively facile translational motions

51 orescent labelling of Nylon microfibers with Nile Red facilitated imaging.

52 An increase in Nile Red fluorescence (a proxy for cellular neutral lipi

53 ion in a membrane pattern was observed using Nile red fluorescence histochemistry.

54 al extracts contained pigments that quenched Nile red fluorescence, a mild bleach solution was used t

55 lastic particles (20-1000 mum) using the dye Nile red, fluorescence microscopy, and image analysis so

56 at sustained local release of the model drug Nile red for 14 days in vivo.

57 Enniatin selectively inhibited the efflux of Nile red from S. cerevisiae cells expressing CaCdr1p or

58 Further, Nile Red has a very poor solubility in aqueous media.

59 asure residence times of the fluorescent dye Nile Red in CYP3A4 incorporated in surface-immobilized l

60 The means of the on-time distributions of Nile Red in DMPC and SOPC vesicles were significantly di

61 concentration, where the first equivalent of Nile Red increased the high-spin fraction by only 13% of

62 rescence emission data of the nonpolar probe Nile red indicate that hydrophobic domains become availa

63 tructure, and the fluorescence properties of Nile red indicate the exposure of hydrophobic surface ar

64 expectedly rapid diffusion of silicate-bound nile red is attributed to the presence of liquidlike sil

65 Mass spectrometry analysis indicates that Nile Red is metabolized sequentially by CYP3A4 to the N-

66 In addition, Nile Red is sequentially oxidized at rates comparable to

67 Nile Red is shown to be a useful probe of the structural

68 ronment-sensitive fluorophores acrylodan and Nile Red, it was observed that the activation of peptide

69 fer from the two-photon absorbing dye to the nile red moiety, with an 8-fold increase in emission com

70 n coefficients for "free" and silicate-bound nile red molecules in the 1:9 films are 3.9 x 10(-10) an

71 Nile Red molecules were observed to associate with and d

72 ciation and dissociation reactions of single Nile Red molecules with a vesicle have been studied.

73 The interactions of single Nile Red molecules with DMPC and SOPC lipid bilayers wer

74 ssfully utilized to trap the hydrophobic dye Nile Red (NR) and the anticancer drug doxorubicin (DOX).

75 on of iron (III) (ferric iron, Fe(3+)) using Nile red (NR) as a complexing agent.

76 we report that the sequential metabolism of Nile Red (NR) is accelerated by the heterotropic alloste

77 favorable kinetics for the release of either Nile Red (NR) or lysozyme (LYS), loaded with gel precurs

78 The emission of Nile Red (NR), a polarity sensing dye, was used to probe

79 ased on selective fluorescent staining using Nile Red (NR), followed by density-based extraction and

80 activity was measured as the accumulation of Nile Red O-positive lipid vacuoles, and osteogenic activ

81 Nile Red/poly(methyl methacrylate) films prepared for co

82 ry low detection limits compared to previous Nile Red/polymer matrix fluorescence vapor sensors.

83 In these plugs, along with Nile Red-positive adipocytes, we found MC/Mph distribute

84 The mechanism of Nile Red release was investigated by monitoring the chan

85 ments performed on "free" and silicate-bound nile red species extracted into chloroform solutions pro

86 hown to be necessary for the accumulation of Nile Red-stained fat in C. elegans.

87 sults provide an explanation for the loss of Nile Red-stained fat in pgp-2(-) animals as well as insi

88 Live imaging studies by Nile red staining suggested that both polar and nonpolar

89 MR) spectroscopy and fluorescence detection (Nile Red staining) to interrogate Mycobacterium tubercul

90 so induced TAG accumulation, as suggested by Nile Red staining.

91 Nile red and a new silanized form of nile red that can be covalently attached to the silicate

92 onstrated for molecules such as estrogen and Nile Red, the absorption of small hydrophobic molecules

93 ttempted to measure fluorescence of released Nile red to determine whether the structural adjustments

94 solvatochromic and fluorogenic properties of nile red to extract both the emission spectrum and the p

95 By using dual fluorochrome dyes (Hoechst and Nile Red) to locate nucleus and cellular cytoplasm, resp

96 Nile red was effluxed efficiently from Saccharomyces cer

97 ccumulate in the brain, whereas encapsulated Nile red was rapidly cleared.

98 .4, the fluorescence of micelle-encapsulated Nile Red was relatively constant, indicating it was reta

99 lization, additional candidate quenchers for Nile Red were identified based on Lewis acid/base intera

100 The near-IR fluorescent probe Nile Red, which has strong solvatochromic behavior, was

101 verages the change in fluorescence of a dye, Nile Red, which is adsorbed on an oxygen plasma-treated

102 hic beads indicates that the interactions of Nile red with C18 bonded phase are different between bea

103 ition for hydrogen-bonding interactions with Nile Red yielded flourescent films with high sensitivity