ライフサイエンスコーパス: nitrite reductase

1 ric oxide reductase, and one had nitrate and nitrite reductase.

2 reductase, flavorubredoxin, or cytochrome c nitrite reductase.

3 a highly sensitive oxygen sensor and/or as a nitrite reductase.

4 ermolecular electron transfer from azurin to nitrite reductase.

5 y sluggishly as electron donors to the green nitrite reductase.

6 esemble those found in ascorbate oxidase and nitrite reductase.

7 rologously expressed Rhodobacter sphaeroides nitrite reductase.

8 that nitrite acts as a positive effector of nitrite reductase.

9 ype 1 and catalytic Type 2 copper centers in nitrite reductase.

10 previously been observed in any cytochrome c nitrite reductase.

11 , as a model for the Cu(T2) center of copper nitrite reductase.

12 ls of xanthine oxidoreductase (XOR), a known nitrite reductase.

13 pseudoazurin that is a donor of electrons to nitrite reductase.

14 ent, and activities of nitrate reductase and nitrite reductase.

15 trification for certain bacterial and fungal nitrite reductases.

16 nate electrons to both blue and green copper nitrite reductases.

17 only as a cofactor in assimilatory sulphite/nitrite reductases.

18 significant identity with other copper-type nitrite reductases.

19 b1 and AHb2, respectively) might function as nitrite reductases.

20 XO and AO, but not hemoglobin, are critical nitrite reductases.

21 The cd(1) nitrite reductase, a key enzyme in bacterial denitrifica

22 The structure of nitrite reductase, a key enzyme in the process of nitrog

23 ide, which inhibits hemoglobin function as a nitrite reductase, abolishes nitrite bioactivation.

24 his nitrite may be reduced back to NO by the nitrite reductase action of deoxygenated hemoglobin, aci

25 ound haem, but the methyl-viologen-dependent nitrite reductase activities associated with the mutated

26 inding affinities, reduction potentials, and nitrite reductase activities of these copper-peptide com

27 als at a specific pH vary by 100 mV, and the nitrite reductase activities range over a factor of 4 in

28 flavoHb possesses nitrosoglutathione and nitrite reductase activities that may account for the pr

29 and can produce nitric oxide via nitrate and nitrite reductase activities.

30 A strain exhibited a severe decrease in both nitrite reductase activity and expression of a nirK-lacZ

31 decreases E(1/2)), an effect that increases nitrite reductase activity and vasodilation at any given

32 hus allowing for the clear-cut monitoring of nitrite reductase activity as a function of quaternary s

33 n resulted in extracts possessing dithionite-nitrite reductase activity but no NADPH-nitrite reductas

34 Recent literature reports suggest a nitrite reductase activity for Hb, converting nitrite in

35 logous promoter, suggesting that the loss of nitrite reductase activity in the PrrA and PrrB mutants

36 Nitrite reductase activity in the PrrA strain could be r

37 This nitrite reductase activity is highly regulated as it is

38 s that can explain the origin of the reduced nitrite reductase activity of deoxyHbE and the accelerat

39 Nitrite reductase activity of deoxyhemoglobin (HbA) in t

40 and NO-modified hemoglobin resulted from the nitrite reductase activity of deoxyhemoglobin and deoxyg

41 ory for nitric oxide (NO), bioactivated by a nitrite reductase activity of deoxyhemoglobin.

42 Here, we characterize the nitrite reductase activity of deoxymyoglobin, which redu

43 ration and quaternary structure and that the nitrite reductase activity of Hb generates NO gas under

44 The nitrite reductase activity of hemoglobin is modulated by

45 the hemoglobin tetramer, suggesting that the nitrite reductase activity of hemoglobin is under allost

46 tivirus expression systems, we show that the nitrite reductase activity of neuroglobin inhibits cellu

47 We evaluated the nitrite reductase activity of unpolymerized sickle hemog

48 cytochrome c reductase activity but no NADPH-nitrite reductase activity or dithionite-nitrite reducta

49 Although nitrite reductase activity was not affected by the crp m

50 of oxygen limitation, nasDEF expression and nitrite reductase activity were significantly induced.

51 We now report that HbS exhibits allosteric nitrite reductase activity with competing proton and red

52 oxyhemoglobin, our findings suggest that the nitrite reductase activity within the circulation, under

53 al N accumulation and chlorophyll synthesis, nitrite reductase activity, and reduced AAO activity.

54 paz inactivation did not decrease nitrite reductase activity, but loss of pseudoazurin and

55 (eNOS) inhibition had no effect on vascular nitrite reductase activity, in RBCs L-NAME, L-NMMA, and

56 and CcoP established to be critical to NirK nitrite reductase activity.

57 d-type Type 1 center, and a somewhat reduced nitrite reductase activity.

58 e activity and an FAD-independent dithionite-nitrite reductase activity.

59 DPH-nitrite reductase activity or dithionite-nitrite reductase activity.

60 oli capable of yielding high levels of NADPH-nitrite reductase activity.

61 unctional gene, nirS (encoding cytchrome-cd1 nitrite reductase), along the salinity gradient of San F

62 In copper nitrite reductases, an electron is delivered from the ty

63 hat are predicted to be monoheme and part of nitrite reductase and a bc1 complex using genome analyse

64 (ORFs), aniA and norB, predicted to encode a nitrite reductase and a nitric oxide reductase, respecti

65 are observed for single molecules of a blue nitrite reductase and are used to extract the microscopi

66 O up-regulates the expression of the plastid nitrite reductase and genes involved in the subsequent i

67 tive polymerase chain reaction targeting the nitrite reductases and dissimilatory sulfite reductase,

68 ced and lacks ammonium transporters, nitrate/nitrite reductases and glutamine:2-oxoglutarate aminotra

69 h the d1 -haem cofactor of dissimilatory cd1 nitrite reductases and haem, via the novel alternative-h

70 important implications for the evolution of nitrite reductases and multicopper oxidases.

71 of both the M. catarrhalis aniA (encoding a nitrite reductase) and norB (encoding a putative nitric

72 cluded those encoding a nitrate reductase, a nitrite reductase, and a nitric oxide reductase.

73 including nitrate transporters, nitrate and nitrite reductase, and metabolic enzymes such as transal

74 iated, respectively, with nitrate reductase, nitrite reductase, and nitric oxide reductase, which cat

75 ion (<1.20 A) structure of a copper protein, nitrite reductase, and of a mutant of the catalytically

76 icyanin, the type 1 copper-binding region of nitrite reductase, and the binuclear CuA binding region

77 ductase, NAD(P)-linked and copper-containing nitrite reductases, and a nitric oxide reductase are inv

78 Third, the reaction undergoes a nitrite reductase/anhydrase redox cycle that catalyzes t

79 d that M. catarrhalis cells that express the nitrite reductase (AniA protein) can produce NO. by redu

80 irects the expression of a copper-containing nitrite reductase, AniA, in response to the presence of

81 Copper nitrite reductases are categorised into two subgroups ba

82 Nitrite reductases are key enzymes that perform the firs

83 phic structures of several copper-containing nitrite reductases are now available.

84 nylglyoxal allowed the identification of two nitrite reductase arginines, R375 and R556, that are pro

85 ls have previously been identified in copper nitrite reductases based on high- to atomic-resolution c

86 Heme-containing nitrite reductases bind and activate nitrite by a mechan

87 ion of N(2)O by both intact chloroplasts and nitrite reductase, but not by nitrate reductase, indicat

88 sibility of the active site pocket of copper nitrite reductase by mutation of a surface-exposed pheny

89 catalysed by the cytoplasmic, NADH-dependent nitrite reductase by the double mutant was almost as rap

90 Cytochrome cd1 nitrite reductase catalyses the conversion of nitrite to

91 Dissimilatory nitrite reductase catalyses the reduction of nitrite (NO

92 Nitrite reductase catalyzes the reduction of nitrite to

93 f NO2(-) reduction by multiheme cytochrome c nitrite reductase (ccNIR) leads us to propose that NO2(-

94 A model for the ferredoxin:nitrite reductase complex is proposed in which the bindi

95 Copper-containing nitrite reductases contain both type 1 and type 2 Cu sit

96 Nitrite reductase contains an unusual blue-green Type 1

97 Like their nitrite reductase counterparts, sulfite reductases requi

98 ormed by either a haem- or copper-containing nitrite reductase (CuNiR) where they receive an electron

99 nitrifier dentrification pathway is a copper nitrite reductase (CuNIR).

100 genase (PHM) or a catalytic center in copper nitrite reductase (CuNiR).

101 The inability of microaerobically grown nitrite reductase-deficient cells to induce nirK-lacZ ex

102 K-lacZ expression was severely impaired in a nitrite reductase-deficient strain of 2.4.3.

103 membrane nitrate reductase (Delta narGH) and nitrite reductase (Delta nirS) produced defects in the e

104 n the (Fe4S4)-siroheme-binding domain of the nitrite reductase demonstrated that these residues were

105 tecture of blue copper oxidase is similar to nitrite reductases, detailed structural alignments show

106 In addition, N. crassa nitrite reductase displays several partial activities in

107 irm that rusticyanin is in the same class as nitrite reductase domain 2, laccase domain 3 and cerulop

108 ganisms with copper containing dissimilatory nitrite reductases, electron donation from a reduced cup

109 ted herein, a single NADH-dependent, soluble nitrite reductase encoded by the nasDE genes is required

110 Neurospora crassa NAD(P)H-nitrite reductase, encoded by the nit-6 gene, is a solub

111 Both membrane nitrate reductase and nitrite reductase enzyme complexes were important for cy

112 Escherichia coli possesses two distinct nitrite reductase enzymes encoded by the nrfA and nirB o

113 e, which need not be the case in the sulfite/nitrite reductase family.

114 pology was observed for ferredoxin-dependent nitrite reductase (Fd-NiR), indicating the genes encodin

115 eral ferredoxin-interacting proteins, namely nitrite reductase, Fd:NADP+ oxidoreductase, and Fd:thior

116 ing nitrate transporters, nitrate reductase, nitrite reductase, ferredoxin reductase, and enzymes in

117 t these positions in all of the Fd-dependent nitrite reductase for which sequences are available, sug

118 expression system for the copper-containing nitrite reductase from a denitrifying variant of Rhodoba

119 the gene nirK, which encodes the copper-type nitrite reductase from a denitrifying variant of Rhodoba

120 e-soaked oxidized and nitrite-soaked reduced nitrite reductase from Alcaligenes faecalis have been de

121 Crystallographic structures of the blue nitrite reductase from Alcaligenes xylosoxidans (AxNiR)

122 ues has been investigated in the blue copper nitrite reductase from Alcaligenes xylosoxidans (NCIMB 1

123 PFV) has been used to study the cytochrome c nitrite reductase from Escherichia coli (ecNrfA) previou

124 e newly characterized three-domain haem-c-Cu nitrite reductase from Ralstonia pickettii (RpNiR) at 1.

125 ype 2 (T2) copper site at high and low pH in nitrite reductase from Rhodobacter sphaeroides.

126 which could correspond to NO location in the nitrite-reductase function of Ngb.

127 In contrast, one nitrite reductase functions both in nitrite nitrogen ass

128 cular, we characterized the diversity of the nitrite reductase gene (aniA), the factor H-binding prot

129 or 19S promoters and PTGS on the endogenous nitrite reductase gene (Nii).

130 n studies revealed a differential pattern of nitrite reductase gene expression where optimal nrfA-lac

131 comparison of plastocyanin (blue), wild-type nitrite reductase (green), and the Met182Thr mutant (blu

132 g in heme proteins such as those observed in nitrite reductase, guanylyl cyclase, and possibly cytoch

133 The blue-green Type 1 center of nitrite reductase has a redox, electron-transfer role, a

134 periments, it has been suggested that copper nitrite reductases have specific electron donors and tha

135 has identity to a motif in the gene encoding nitrite reductase in strain 2.4.3 is critical for nor op

136 anthine oxidoreductase (XOR) is an important nitrite reductase in the heart and kidney.

137 ded nitrite enhanced the in vivo activity of nitrite reductase in the narB mutant; this suggests that

138 utant (Met182Thr) of Rhodobacter sphaeroides nitrite reductase in which the axial methionine has been

139 ribe properties of a penta-heme cytochrome c nitrite reductase in which the distal His has been subst

140 d(1), the prosthetic group of dissimilatory nitrite reductases in anaerobic, denitryfying bacteria.

141 meproteins have been reported to function as nitrite reductases in mammalian cells, it is unknown whe

142 ession of nirK, the structural gene encoding nitrite reductase, in these strains was significantly de

143 Cytochrome c nitrite reductase is a dimeric decaheme-containing enzym

144 mined whether the primary human erythrocytic nitrite reductase is hemoglobin as opposed to other eryt

145 cyanide for reduced versus oxidized forms of nitrite reductase is immediately revealed, as is the pre

146 In contrast, the nirB nitrite reductase is optimally synthesized only when nit

147 odes an anaerobically induced outer membrane nitrite reductase) is necessary for expression.

148 ded beta-propeller domain of cytochrome cd1 (nitrite reductase) is seen, from a 1.28 A resolution str

149 association with the physiological partner, nitrite reductase, is only affected by the Met16Phe muta

150 e expression of the gene aniA, which encodes nitrite reductase, is regulated by oxygen depletion and

151 Siroheme, the cofactor for sulfite and nitrite reductases, is formed by methylation, oxidation,

152 gh AO has structural similarity to bacterial nitrite reductases, it is unknown whether AO-catalyzed n

153 Faster nitrite reductase kinetics for CDB3-bound hemoglobin sug

154 ubtilis, NsrR represses transcription of the nitrite reductase (nasDEF) genes that are under positive

155 genes (NOL2 and NOL3) and nitrate (NIA1) and nitrite reductase (NII1), generating single and double D

156 he role of NO3- and NO2- in the induction of nitrite reductase (NiR) activity in detached leaves of 8

157 d to both nitric oxide dioxygenase (NOD) and nitrite reductase (NiR) activity.

158 NO is produced by nitrite reductase (Nir) and reduced to nitrous oxide by

159 nder anaerobic conditions, copper-containing nitrite reductase (NiR) of Rhodobacter sphaeroides yield

160 anaerobically by anaerobic respiration using nitrite reductase (Nir) to convert nitrite to NO and nit

161 Banding patterns of nitrate reductase (NR), nitrite reductase (NiR), and glutamine synthetase (GS) f

162 inetics of a copper-containing dissimilatory nitrite reductase (NiR).

163 oxidation, formate dehydrogenase (FDH) and a nitrite reductase (NirK).

164 These data suggest that NO generated via nitrite reductase NirS contributes to the regulation of

165 the essential cofactor of the cytochrome cd1 nitrite reductase NirS.

166 Analysis of expressed genes for nitrite reductase (nirS) and a nitrogenase subunit (nifH

167 es: the mononuclear type two (T2) Cu site in nitrite reductases (NiRs) and the trinuclear Cu cluster

168 Copper-containing nitrite reductases (NiRs) are sub-divided into blue and

169 absorption spectral changes present in green nitrite reductases (NiRs) due to a thermodynamic equilib

170 inhibition, whereas all but the periplasmic nitrite reductase NrfA provide protection against neutro

171 ransfer from NrfH, the electron donor to the nitrite reductase NrfA.

172 ite as a terminal electron acceptor requires nitrite reductase (nrfA) as a D. vulgaris nrfA mutant ca

173 lso affect NarP-dependent gene regulation of nitrite reductase (nrfABCDEFG) and aeg-46.5 gene express

174 ctron-transfer kinetics to the physiological nitrite reductase of Pseudomonas.

175 The nitrate and nitrite reductases of Bacillus subtilis have two differe

176 tron donation experiments using three copper nitrite reductases, one green and two blue, and five cup

177 deoxyhemoglobin is the primary erythrocytic nitrite reductase operating under physiological conditio

178 duced during nitrate respiration include the nitrite reductase operon (nasDEF) and the flavohemoglobi

179 erent expression profile for the alternative nitrite reductase operon encoded by nirBDC under high-ni

180 nite-nitrite reductase activity but no NADPH-nitrite reductase or NADPH-cytochrome c reductase activi

181 Cytochrome c nitrite reductases perform a key step in the biogeochemi

182 w physiological function for hemoglobin as a nitrite reductase, potentially contributing to hypoxic v

183 y the addition of a 131-bp fragment from the nitrite reductase promoter.

184 , including nrfA, which encodes cytochrome c nitrite reductase, providing strong evidence that there

185 The nitrite reductase reaction does not appear to account fu

186 rite to generate nitric oxide (NO) through a nitrite reductase reaction.

187 HbA) through several reactions including the nitrite reductase, reductive nitrosylation, and still co

188 Formate-dependent nitrite reductase regulator (FNR) is an oxygen-sensitive

189 roxylamine reductase (PG0893) and a putative nitrite reductase-related protein (PG2213) in P. gingiva

190 trate, is a more efficient electron donor to nitrite reductase relative to Fd.

191 rite to ammonium by assimilatory nitrate and nitrite reductase, respectively.

192 of the genes encoding nitrate reductase and nitrite reductase, resulting in strains that were unable

193 ferredoxin to a positively charged region of nitrite reductase results in elimination of exposure of

194 The structure of nitrite reductase shows a broad similarity to the hemopr

195 ry nitrate reductase) and nasF (required for nitrite reductase siroheme cofactor formation), constitu

196 Shewanella oneidensis cytochrome c nitrite reductase (soNrfA), a dimeric enzyme that houses

197 The implications of the nitrite reductase structure for understanding multi-elec

198 at hemoglobin is an allosterically regulated nitrite reductase, such that oxygen binding increases th

199 f bacteria that have an assimilatory nitrate/nitrite reductase system (NAS) can use nitrate or nitrit

200 ll living systems as part of the sulfite and nitrite reductase systems.

201 he nir operon encodes a soluble, cytoplasmic nitrite reductase that catalyses NADH-dependent reductio

202 r and a post-translationally redox-regulated nitrite reductase that generates NO under six-to-five-co

203 or hemoglobin as an allosterically regulated nitrite reductase that may mediate nitric oxide (NO)-dep

204 est an additional role for cytochrome c as a nitrite reductase that may play an important role in reg

205 unctional analysis of T1Cu centre mutants of nitrite reductase that perturb the redox potential and t

206 lobin A (HbA) is an allosterically regulated nitrite reductase that reduces nitrite to NO under physi

207 G is coregulated with the siroheme-dependent nitrite reductase, the cysF gene is regulated by sulfur

208 a coli K-12 nrf operon encodes a periplasmic nitrite reductase, the expression of which is driven fro

209 ion, which affects the inducible cytoplasmic nitrite reductase, the major source of nitric oxide duri

210 Transcription of genes encoding nitrate and nitrite reductases, the enzymes responsible for NO produ

211 Only a single isozyme of nitrite reductase was detected in surveys of three tetra

212 The gene encoding nitrite reductase was not found in 2.4.1.

213 cea oleracea) leaf ferredoxin (Fd)-dependent nitrite reductase was treated with either the arginine-m

214 15 degreesC, although nitrate reductase and nitrite reductase were still active.

215 uctase A and the cytoplasmic, NADH-dependent nitrite reductase were unaffected by the narK and narU m

216 some nitrogen acquisition transcripts (e.g. nitrite reductase) were upregulated at depth compared wi

217 rall, HAO is seen to act like a cytochrome c nitrite reductase, which catalyzes the six-electron redu

218 bin as an allosterically and redox-regulated nitrite reductase whose "enzyme activity" couples hypoxi

219 Modification of nitrite reductase with pyridoxal-5'-phosphate, followed

220 nce that Hb exhibits enzymatic behavior as a nitrite reductase, with maximal NO generation rates occu

221 e present the structures of wild-type copper nitrite reductase (wtNiR) from Alcaligenes xylosoxidans