ライフサイエンスコーパス: nitro

1 nd endothelium-independent vasodilatation (% Nitro).

2 he catalyst differs significantly (ketone vs nitro).

3 ional groups such as ester, cyano, keto, and nitro.

4 ng conjugated nitro dienes (in particular, 1-nitro 1,3-diene), an unusual and highly reactive motif w

5 tamate receptor antagonist NBQX (2,3-dioxo-6-nitro-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamid

6 ation strategies, derivatives of 4, 4'-bis(5-nitro-1,2,3-2H-triazole) were designed, synthesized, and

7 cosms for their ability to degrade the IM, 3-nitro-1,2,4-triazol-5-one (NTO).

8 The reaction of 3-amino-5-nitro-1,2,4-triazole with nitrous acid produces the corr

9 Some of the alpha-nitro-1,3-dicarbonyl intermediates exhibit enhanced reac

10 of masked 2,3-diaminoindole 1 from 2-iodo-3-nitro-1-(phenylsulfonyl)indole (2) has been developed.

11 f the novel synthetic CB1 PAM, 6-methyl-3-(2-nitro-1-(thiophen-2-yl)ethyl)-2-phenyl-1H-indole (ZCZ011

12 small-molecule inhibitor benzo[b]thiophene,6-nitro-,1,1-dioxide (Stattic), or by STAT3 knockdown by s

13 3-Nitro-1H-1,2,4-triazole-based amides with a linear, rigi

14 lability of (18)F-labeled and unlabeled 2-(2-nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl)-

15 l for the efficient synthesis of (1-methyl-2-nitro-1H-imidazol-5-yl)methanol, which is a key intermed

16 can be converted into a range of 1-methyl-2-nitro-1H-imidazole-based precursors of bioreductive prod

17 gent and regioselective approach to 5-aryl-4-nitro-1H-pyrazoles was developed by guided transition-me

18 ed transition-metal-catalyzed arylation of 4-nitro-1H-pyrazoles.

19 ormation system (AEGIS), Z and P, (6-amino-5-nitro-2(1H)-pyridone and 2-amino-imidazo[1,2-a]-1,3,5-tr

20 th two nonstandard nucleobases (Z, 6-amino-5-nitro-2(1H)-pyridone and P, 2-amino-imidazo[1,2-a]-1,3,5

21 ple consecutive 'non-standard' ( , 6-amino-5-nitro-2(1H)-pyridone, and , 2-amino-imidazo[1,2-a]-1,3,5

22 the samples were derivatized with 4-chloro-7-nitro-2,1,3-benzoxadiazole (NBD-Cl) prior to CE-UV analy

23 6-Nitro-2,3-dihydroimidazo[2,1-b][1,3]oxazole derivatives

24 roducts of HMX hydrolysis such as nitrite, 4-nitro-2,4-diazabutanal, formaldehyde, nitrous oxide, for

25 n treatment with the anion channel blocker 5-nitro-2-(3-phenylpropylamino)-benzoic acid (NPPB), possi

26 mitoyl-sn-glycero-3-phosphoethanolamine-N-(7-nitro-2-1,3-benz oxadiazol-4-yl)(biotin-cap-NBD-PE) lipi

27 oleoyl-sn-glycero-3-phosphoethanolamine-N-(7-nitro-2-1,3-benzoxadiazol-4-y l)], incorporated into a p

28 compounds 7 were prepared by reduction of 7-nitro-2-aryl-1,2-benzisoselenazol-3(2H)-ones 3 and 6 wit

29 aphy-free synthesis is the coupling of (R)-4-nitro-2-butanol and glyoxal (trimeric form) mediated by

30 e-Gly (fusion inhibitor peptide [FIP]) and 4-nitro-2-phenylacetyl amino-benzamide (AS-48) have simila

31 rbonate, which affords in crystalline form 3-nitro-3,4,6-trideoxy-alpha-D-glucose, a nitro sugar ster

32 tituted amino acids (2S,3R,4S,5S)-1-methyl-4-nitro-3,5-diphenylpyrrolidine-2-carboxylic acid (endo-6)

33 c acid (endo-6) and (2S,3S,4R,5S)-1-methyl-4-nitro-3,5-diphenylpyrrolidine-2-carboxylic acid (exo-6),

34 yielded the primary explosive bis(4-diazo-5-nitro-3-oxopyrazolyl)methane (8), which showed superior

35 s were confirmed using biotinylated methyl-3-nitro-4-(piperidin-1-ylsulfonyl) benzoate (NPSB-B), a ch

36 Roxarsone (3-nitro-4-hydroxybenzenearsonic acid) is a pentavalent aro

37 s with nitrones to give highly substituted 4-nitro-4-isoxazolines in high yields.

38 s were treated with the protective drug 2-(2-nitro-4-trifluoromethylbenzoyl)-1, 3 cyclohexandione (NT

39 e, this structurally related 7-substituted 2-nitro-5,6-dihydroimidazo[2,1-b][1,3]oxazine class was fu

40 a-Baylis-Hillman (MBH) acetates into alkyl 3-nitro-5-(aryl/alkyl)isoxazole-4-carboxylates is describe

41 Among them, 2-[2-(3-methyl-4-nitro-5-isoxazolyl)vinyl]pyridine and 2-(benzylsulfonyl)

42 ther applied to the system of irreversible 2-nitro-5-thiobenzoate oxidation used in the detection of

43 Substitution with hydroxy, cyano, nitro, acetamido, and fluoro led to high inhibitory acti

44 al Michael-type addition of the imine to the nitro-alkene followed by a cyclization event.

45 ugh [4 + 2] cycloaddition of 1-azadienes and nitro-alkenes.

46 reported formal (3 + 3) annulation of alpha-nitro-alpha,beta-enals and 2,2-dimethyl-1,3-dioxan-5-one

47 alpha-Nitro-alpha,beta-enals can act as well as highly reactiv

48 alence of the fluorinated reagent with alpha-nitro-alpha-diazo carbonyls was established.

49 m temperature to afford enantioenriched beta-nitro amines in good yields and high enantioselectivity,

50 nd explained the loss of fluorescence in the nitro analogue.

51 A new series of nitro analogues of the duocarmycins was prepared and eva

52 Since both 4-nitro and 4-amino L-proline esters are efficient organoc

53 ing the use of sensitive substituents (e.g., nitro and bromide groups).

54 n of electron-withdrawing groups (EWGs) like nitro and cyano at the phenyl ring, leading to absorptio

55 isomers recombined forming the corresponding nitro and nitroso compounds, and the most reactive cis/s

56 onal groups, such as ester, ketone, nitrile, nitro, and triazene are well tolerated.

57 The stereodirecting effect of the 2-nitro- and 2-cyanobenzyl groups attached at the remote p

58 In this work, N-nitro- and N-nitroamino-functionalized mono- and bis(1,2

59 Electrophilic fatty acid species, including nitro- and oxo-containing fatty acids, display salutary

60 , including direct comparison of 3-cyano-, 3-nitro-, and 3-phenyl-substituted BF2 formazanate complex

61 with allyl, benzyl, 4-bromo-, 4-methoxy-, 4-nitro-, and 4-(3,4-dimethoxyphenyl)benzyl, propyl, and p

62 from 2-nitroperchloro-1,3-butadiene and para-nitro aniline, and generated the potential energy profil

63 Initially l-nitro-arginine (LNNA) was given to block endogenous NO p

64 egantly exploited for selective detection of nitro aromatic compounds (NACs).

65 Phenolic and nitro-aromatic compounds are extremely toxic components

66 e saturation vapor pressures of phenolic and nitro-aromatic compounds are measured using Knudsen Effu

67 For example, 24-DNP and other nitro-aromatic compounds should readily photodegrade in

68 s was applied for the selective detection of nitro-aromatic compounds.

69 at 410nm and 625nm among the other tested nitro-aromatic compounds.

70 or other chemical compounds including common nitro-aromatic explosives and inorganic oxidative compou

71 nts in this study suggest these phenolic and nitro-aromatic will partition into the condensed state f

72 sed off-matrix was achieved using 4-fluoro-3-nitro-azidobenzene (FNAB) cross-linker.

73 ieved via azide group activity of 4-fluoro-3-nitro-azidobenzene (FNAB), which act as cross-linker and

74 hese findings, the different reactivities of nitro-based organic explosives are rationalized as an in

75 he acid/base-catalysed Kemp elimination of 5-nitro-benzisoxazole forming 2-cyano-4-nitrophenol has lo

76 from [Ir(cod)Cl]2, allyl acetate, 4-cyano-3-nitro-benzoic acid, and (R)-MeO-BIPHEP catalyzes the cou

77 even series of indenoisoquinolines bearing 3-nitro bioisosteres were synthesized.

78 tion of reactive oxygen species (ROS) with a nitro blue tetrazolium (NBT) assay.

79 n, the TCP-C60 film induced the reduction of nitro blue tetrazolium to diformazan in the presence of

80 g peroxisome abundance using the small probe Nitro-BODIPY, which in vivo fluoresces selectively insid

81 ogen-bonding interactions and an interactive nitro chain in the crystal structure.

82 nerate a thiolate-ligated, nonheme iron(III)-nitro complex, [Fe(III)(NO2)(N3PyS)](+), which was chara

83 y facile dealkylation to release the primary nitro compound.

84 ighting the differences in the metabolism of nitro compounds among mycobacterial species and emphasiz

85 t higher order hydrogen-bonded aggregates of nitro compounds and acids are the kinetically competent

86 ions into this surprising effect reveal that nitro compounds induce a switch from first order concent

87 -NH2, -NHCH3, and -OH) to the corresponding nitro compounds is described by use of nonanebis(peroxoi

88 A cocatalytic effect of nitro compounds is described for the B(C6F5)3.H2O cataly

89 atic carboxylic acids to their corresponding nitro compounds using nitronium tetrafluoroborate and si

90 lyzing the transfer hydrogenation from AB to nitro compounds, leading to the green synthesis of quina

91 sted acid and second order dependence in the nitro compounds.

92 Nitro-conjugated linoleic acid (NO2-CLA) is preferential

93 Nitro-conjugated linoleic acids (NO2-cLA), endogenous ni

94 he potential conversion of nitro-linoleic to nitro-conjugated linoleic acids was explored via a facil

95 served, and competitive binding studies with nitro-containing additives suggest that 1,3-disiloxanedi

96 actants, a facile and selective reduction of nitro-containing aromatics and heteroaromatics can be ef

97 safe approach to highly valued reductions of nitro-containing compounds.

98 onal groups, such as the ester, aryl ketone, nitro, cyano, and amide functions.

99 A wide variety of functional groups (nitro, cyano, halo, alkyl, amido, and thioether) was tol

100 atalytic hydrogenation of the intermediate 4-nitro cycloadducts.

101 trans-2-Aryl-3-nitro-cyclopropane-1,1-dicarboxylates, upon treatment wi

102 enantiomerization transition state of the 2-nitro derivative the ortho substituent is close to the N

103 reat as it can be extended to heteroaromatic nitro derivatives and can be run on solid support.

104 mation exists for the potentially more toxic nitro-derivatives of PAHs (NPAHs).

105 for the reduction of aromatic and aliphatic nitro-derivatives to amines has been investigated.

106 scriptions of naturally occurring conjugated nitro dienes (in particular, 1-nitro 1,3-diene), an unus

107 ograms owing to potential toxicity issues, a nitro drug is now being used successfully as part of a c

108 ial species and emphasizing the potential of nitro drugs as antibacterials in various bacterial speci

109 We describe here the rehabilitation of nitro drugs for the treatment of trypanosomatid diseases

110 wardly gives rise to the formation of (Z)-2-(nitro((E)-p-substitutedphenyldiazenyl)methylene)thiazoli

111 sed, the corresponding syn-alpha-amino-gamma-nitro ester is obtained with almost complete enantiocont

112 alpha-Nitro esters and amides were obtained in good overall yi

113 had utilized this in the synthesis of alpha-nitro esters from nitroalkanes.

114 afe, rapid method for the synthesis of alpha-nitro esters via the trapping of nitronium ions.

115 of different substituents (methyl, halogens, nitro, etc.) at the indole of D-Trp significantly influe

116 SO4(2-), and NO3(-)) at 100-fold ratios nor nitro-explosives of trinitrotoluene (TNT), hexahydro-1,3

117 rs, there has been an increasing interest in nitro fatty acids (NO2-FA) as signaling molecules formed

118 t to determine whether OA-NO2 , an exemplary nitro-fatty acid, has the capacity to inhibit cutaneous

119 rated fatty acids give rise to electrophilic nitro-fatty acids (NO2 -FAs), such as nitro oleic acid (

120 Nitro-fatty acids (NO2-FAs) are the product of the react

121 Nitro-fatty acids are reactive signaling mediators that

122 Nitro-fatty acids can modify specific signaling pathways

123 One of the signaling cascades activated by nitro-fatty acids is the Keap1-Nrf2 pathway.

124 none that is differentially expressed in the nitro-FMN reductase superfamily during redox cycling.

125 enases, constitute a new subclass within the nitro-FMN reductase superfamily.

126 fold that is structurally reminiscent of the nitro-FMN reductase superfamily.

127 3 and the displacive phase transition of the nitro-form are completely inhibited (at least up to 3 GP

128 er (18)O2 show that both oxygen atoms in the nitro function of CAM derive from O2.

129 he reaction proceeds through a PCET promoted nitro functional group transfer pathway.

130 A Zn/AcOH-mediated reduction of the nitro functionality followed by condensation onto benzal

131 DC3, BDC = 1,4-benzenedicarboxylate) and its nitro-functionalized derivative (Sc2(NO2-BDC)3) and comp

132 While N-nitro-functionalized products are thermally unstable and

133 A denitration step renders the nitro group "traceless" and delivers secondary, tertiary

134 osine (3-NT) from Tyrosine (Tyr) by adding a nitro group (-NO2) with nitrating agents.

135 exploration of the chemical potential of the nitro group and a putative reaction mechanism are discus

136 By implementation of both the azido and nitro group as sulfide-reactive functionalities on the s

137 e replacement of the potentially genotoxic 3-nitro group by 3-chloro and 3-fluoro substituents, resul

138 amine group to one of the two O atoms in the nitro group denotes the most accessible route in the uni

139 Mild reduction of the nitro group followed by an acid-mediated cyclodehydratio

140 Reduction of the nitro group followed by derivatization of the so formed

141 Subsequent reduction of the nitro group followed by hydrolysis of the oxazoline ring

142 ams can be obtained via hydrogenation of the nitro group followed by in situ cyclization.

143 The experiments indicated that the nitro group has influence on regioselectivity of the rea

144 now show the typical activity of Au(0)NPs in nitro group hydrogenation.

145 from energetically favorable stacking of the nitro group in with pi-electrons of the adjacent base.

146 Introduction of a para-nitro group into the benzene ring of the diene enabled s

147 This AAD process only occurred when a nitro group is bonded to the 4-position of the initial e

148 (15)N nitro group labeled RDX ((15)N-[RDX], 50 atom %) was spi

149 n aryl-amine precursor (NH2-CAM) to the aryl-nitro group of CAM catalyzed by the non-heme diiron clus

150 Unique features include stacking of the nitro group on Z with the adjacent nucleobase ring in th

151 G:C pairs, perhaps to accommodate the large nitro group on Z.

152 9 was synthesized by (18)F displacement of a nitro group or an iodonium ylide.

153 imination occurred, leading to the selective nitro group reduction reaction on the syn-alpha-amino es

154 elopment for H2S detection include azide and nitro group reduction, nucleophilic attack, and CuS prec

155 Here we demonstrate that incorporation of a nitro group significantly stabilizes the LUMO, and hence

156 ociated ion channel that is used to target a nitro group to redox-mediated regulatory sites on the re

157 dazole derivatives directed by a manipulable nitro group was developed.

158 troarenes at a position ortho or para to the nitro group with formation of anionic sigma(H) adducts.

159 uorine and chlorine may substitute for the 3-nitro group with minimal loss of Top1 poisoning activity

160 ration (i.e., the irreversible addition of a nitro group) of the Alzheimer-related peptide amyloid-be

161 leavages on the fatty acid backbone near the nitro group, allowing its localization within the FA aky

162 avior between pyrrolidines with or without a nitro group, demonstrating the strong nitro-group-depend

163 uperior selectivity for hydrogenation of the nitro group, outperforming both conventional Pd nanopart

164 This reaction proceeds via reduction of the nitro group, resulting in in situ imine formation follow

165 acids as inexpensive, readily available, and nitro group-free aminating reagents.

166 ization onto the secondary aromatic ring and nitro group.

167 Previously reported representatives bear a 3-nitro group.

168 beta- and delta-carbons with respect to the nitro group.

169 henols showed an exponential decay, with the nitro-group on the aromatic ring found to control the fo

170 hout a nitro group, demonstrating the strong nitro-group-dependent periselectivity.

171 separately reduced both the para- and ortho-nitro groups and produced glycosylated products that acc

172 gest that 1,3-disiloxanediols bind weakly to nitro groups but are strongly activating for catalysis.

173 Photoexcitation of nitro groups by a high-energy laser is not required; the

174 sibly because their less sterically hindered nitro groups can be released more easily as nitrite and

175 tivity to afford products with the vinyl and nitro groups cis to each other is observed with a 4-subs

176 is carried out in an (16)O2 atmosphere, CAM nitro groups contain both (18)O and (16)O, suggesting th

177 n with 2,3-dimethoxy-8,9-methylenedioxy or 3-nitro groups exerted strong effects on antiproliferative

178 0.9), compounds containing halogen atoms or nitro groups gave a lower predicted ESI response.

179 om the separate reduction of the quinone and nitro groups in the molecules.

180 The nitro groups of energetic compounds are readily reduced

181 It also reduced the nitro groups of Nit(V), forming p-aminophenyl arsenate (

182 ineNO- group was added para and ortho to the nitro groups of the dinitrophenyl ring.

183 which favour the preferential adsorption of nitro groups.

184 hance selectivity toward analytes containing nitro groups.

185 o the electrochemical reduction of the three nitro-groups on the TNT molecule.

186 lopenta[b]indolines with versatile vinyl and nitro-groups.

187 which in most cases gives N'-(het)aryl-N'-[2-nitro(het)aryl]hydrazides in good yields.

188 This route to the N'-(het)aryl-N'-[2-nitro(het)aryl]hydrazides, which works well with benzo-

189 imple feedstock building blocks: olefins and nitro(hetero)arenes.

190 One of the factors is transformation of a nitro into an amine group via reduction with a low-valen

191 rm skin sites: (i) control; (ii) 10 mm N(G) -nitro-l-arginine (l-NNA), a non-specific NOS inhibitor;

192 d with the nitric oxide synthase inhibitor N-nitro-l-arginine (l-NNA, 200 mum) and in nNOS-knockout (

193 solution (Control), 400 nm ET-1, 10 mm N(G) -nitro-l-arginine (l-NNA; a NOS inhibitor) or a combinati

194 Molsidomine or NG-nitro-L-arginine methyl ester (L-NAME) or saline were ap

195 nd NOS inhibition in cancer cells using N(G)-nitro-l-arginine methyl ester (l-NAME), we demonstrate t

196 -IR with the constitutive NOS inhibitor N(G)-nitro-l-arginine methyl ester (L-NAME).

197 tric oxide (NO) synthase inhibitor N(omega) -nitro-l-arginine methyl ester (P > 0.05), indicating tha

198 ed before and during NO inhibition (N(omega)-nitro-l-arginine methyl ester [L-NAME]).

199 N(omega)-Nitro-L-arginine methyl ester and 1H-[1,2,4]-oxadiazolo-

200 NOS inhibitor N(G)-nitro-L-arginine methyl ester attenuated the endothelial

201 ypertensive challenges using either N(omega)-nitro-L-arginine methyl ester hydrochloride (L-NAME)/hig

202 resence of DTT and the NO inhibitor N(omega)-nitro-L-arginine methyl ester hydrochloride, the ability

203 The eNOS inhibitor N(G)-Nitro-l-arginine methyl ester mimicked anti-VEGF/VEGFR d

204 rsed the inhibitory effects of ADMA and N(G)-nitro-l-arginine methyl ester on inducible NOS (macropha

205 N(omega)-nitro-l-arginine methyl ester reduced vasodilation to fl

206 Further, the inhibition of eNOS (l-N(G)-nitro-L-arginine methyl ester), Mas (A-779), and SIRT1 (

207 ed NOX4 expression was abrogated by N(omega)-nitro-l-arginine methyl ester, an inhibitor of NOS.

208 glutathionylation and eNOS-derived N(omega)-nitro-L-arginine methyl ester-sensitive superoxide forma

209 tion of nitric oxide synthase with N(omega) -nitro-l-arginine methyl ester.

210 nitric oxide synthase (eNOS) inhibitor N(G)-nitro-L-arginine methyl ester.

211 ed by the nitric oxide synthase inhibitor NG-nitro-l-arginine methyl ester.

212 L-NAME (N(omega)-nitro-L-arginine methyl ester; nitric oxide synthase inh

213 of nitric oxide synthase via the inhibitor N-nitro-l-methyl-arginine ester.

214 ncharacterized enzymes exclusively produce 5-nitro-L-tryptophan, a previously unknown biosynthetic in

215 The mpk6-2 mutant was sensitive to 3-nitro-l-tyrosine (NO2 -Tyr) treatment with respect to mi

216 nstrate that adding a tyrosine derivative, 3-Nitro-L-tyrosine, into DMEM can mitigate the degradation

217 class of inhibitors offers an attractive non-nitro lead series targeting the essential and vulnerable

218 FAs), such as nitro oleic acid (OA-NO2 ) and nitro linoleic acid (LNO2 ).

219 c standards, and the potential conversion of nitro-linoleic to nitro-conjugated linoleic acids was ex

220 ere, we examine the endogenous occurrence of nitro-linolenic acid (NO2-Ln) in Arabidopsis and the mod

221 whereas an enantioselective organocatalytic nitro-Mannich reaction enabled the synthesis of the lead

222 elective addition of nitroalkanes to imines (nitro-Mannich reaction), mediated by an iron(II) catalys

223 able chemical synthesis: Complexity-building nitro-Mannich/lactamization cascade processes allowed fo

224 on-withdrawing functional groups such as the nitro moiety at position 7 led to a noticeable improveme

225 e privileged nature of a properly positioned nitro moiety on the 3-aryl group.

226 Contamination levels observed for the two nitro musks (musk xylene and musk ketone) are significan

227 developed procedure was applied to determine nitro musks in environmental water samples and was demon

228 analysis, was developed for the analysis of nitro musks in environmental water samples.

229 are representative of antibacterial agents, nitro-musks, and surfactants, respectively.

230 4-Nitro-N-[2-(2-phenylsulfanylethylamino)ethyl]benzamide h

231 2-Nitro-N-alkyl-N-(2-oxo-2-phenylethyl)benzenesulfonamide

232 Using N-methyl-N-nitro-N-nitroso-guanidine mutagenesis and selection, a m

233 eatment of DNA-methylating agent N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) and antimetabolite 6-thi

234 caused by the methylating agent N-methyl-N'-nitro-N-nitrosoguanidine, and thereby enables Escherichi

235 typic Sn1-type methylating agent N-methyl-N'-nitro-N-nitrosoguanidine.

236 wing: (1) how ROSI and/or GW9662 (2-chloro-5-nitro-N-phenylbenzamide; PPARgamma antagonist) injected

237 Compounds with unsubstituted and nitro naphthalimide (1 and 2) show excellent selective f

238 e more potent than cisplatin and N-methyl-N'-nitro-nitrosoguanidine (MNNG, a common DNA-alkylating ch

239 nched due to the electrophilic nature of the nitro (-NO2) groups on the TNT molecule.

240 omatic hydrocarbons (PAHs), PAH derivatives (nitro- (NPAH) and oxy-(OPAH)), organic carbon (OC), and

241 cting and indirect-acting mutagens, namely 4-nitro-o-phenylenediamine, sodium azide, mitomycin C, ben

242 philic fatty acid nitroalkene derivative, 10-nitro-octadec-9-enoic acid (nitro-oleic acid, NO2-OA), w

243 in rats, and allowed the identification of 4-nitro-octanedioic acid (NO2-8:0-diCOOH) as the most abun

244 Enals, enones, conjugated esters and nitro olefins have been employed as Michael acceptors, w

245 Asymmetric hydrogen-bonding activation of nitro-olefins facilitated the 1,3-dipolar cycloaddition

246 ael reactions of a series of water-insoluble nitro-olefins in an aqueous medium.

247 facile domino Michael-Michael reaction with nitro-olefins to afford the corresponding nitrocyclohexa

248 In particular, 10-nitro oleic acid (10-NO2-OA) potently induces Nrf2-depen

249 philic nitro-fatty acids (NO2 -FAs), such as nitro oleic acid (OA-NO2 ) and nitro linoleic acid (LNO2

250 The electrophilic lipid 10-nitro-oleic acid (NO2-OA) inhibited hydrolase activity a

251 In contrast, the anti-inflammatory agent 10-nitro-oleic acid (NO2-OA), a component of the Mediterran

252 We have previously studied the effects of nitro-oleic acid (OA-NO2) on the human endothelial cell

253 Effects of nitro-oleic acid (OA-NO2) on TRP channels were examined

254 synthetic (rosiglitazone) or endogenous (10-nitro-oleic acid) PPARgamma agonists strongly up-regulat

255 e derivative, 10-nitro-octadec-9-enoic acid (nitro-oleic acid, NO2-OA), were investigated in multiple

256 ng complication of premature birth caused by nitro-oxidative insult to the developing retinal vascula

257 se I, tetrahydrobiopterin, NO formation, and nitro-oxidative stress as well as eNOS uncoupling in the

258 and, in some cases, the formation of PAH and nitro-PAH compounds are discussed in detail, and suggest

259 ns are provided to minimize the formation of nitro-PAH compounds through aftertreatment design optimi

260 c aromatic hydrocarbon (PAH), and alkyl- and nitro-PAH emissions and assess their genotoxic potential

261 arbons (PAH) and their nitrated derivatives (nitro-PAH).

262 polycyclic aromatic hydrocarbons (PAHs) and nitro-PAHs (NPAHs) with NO3/N2O5, OH radicals, and O3 we

263 The results showed that emission of nitro-PAHs may be decreased to a greater extent by using

264 Nitro-PAHs were identified only during the UDC and not f

265 on of 4-Amino Phenol (AP), Phenol (Ph) and 4-Nitro Phenol (NP).

266 with four photocleavable groups of dimethoxy nitro phenyl ethyl (DMNPE), located on the four terminal

267 aditional chromogenic ELISA test employing p-nitro-phenyl phosphate (pNPP).

268 We previously reported that the bis-nitro-phenyl ROMK inhibitor VU591 exhibits voltage-depen

269 cussion about the nature, origin, or role of nitro phospholipids (NO2-PL) was reported up to now.

270 alytic hydrogenation of (S)-alpha-amino-beta-nitro-phosphonate 2d gives enantiopure (S)-alpha,beta-di

271 to afford tetrasubstituted alpha-amino-beta-nitro-phosphonates.

272 diesters (PMIDE) enables the synthesis of 1-nitro-PMIDE 10 and thus of azabenz-annulated perylene de

273 hesized by fluorination of the corresponding nitro precursor, followed by acidic removal of the 2-met

274 dation of an aryl-amine substrate to an aryl-nitro product catalyzed by the N-oxygenase CmlI in three

275 of an aryl-nitroso intermediate to the aryl-nitro product.

276 mitted to a new conservative treatment, the "Nitro-Push Blind Technique".

277 uction of TNT in the mitochondria, forming a nitro radical that reacts with atmospheric oxygen, gener

278 eroxide anion and hydroxyl radicals, organic nitro-radicals (ABTS, DPPH) and to inhibit lipid peroxid

279 n nor-beta-lapachone derivatives including a nitro redox center showed that reduction of the compound

280 study to use electrochemistry to generate a nitro reduction metabolite as a standard for a liquid ch

281 O as the catalyst with AgNO2 utilized as the nitro source as well as terminal oxidant in the presence

282 H2O plays a dual role as catalyst as well as nitro source.

283 An NHC-catalyzed nitro-Stetter/elimination/Stetter reaction sequence empl

284 Assessing nitro-stilbenoids, both approaches suggested nitrostilbe

285 rey-Chaykovsky cyclopropanation reactions of nitro styrenes.

286 uently reacts with the nitronium ion to form nitro substances.

287 remarkable enzyme-induced distortion of the nitro-substituent out of the plane of the phenyl ring by

288 earrangements of diphenylamine (DPA) and its nitro substituents (NDPA).

289 wing groups like halides, carboxyesters, and nitro substituents.

290 tuent and the number of electron-withdrawing nitro substituents.

291 lization of a partial positive charge on the nitro-substituted carbon in both transition state and pr

292 nitro substitution in the complete series of nitro-substituted octaethylporphyrins.

293 Nitro-substituted polyhalogenated butadienes are valuabl

294 tructural effects of an increasing degree of nitro substitution in the complete series of nitro-subst

295 rm 3-nitro-3,4,6-trideoxy-alpha-D-glucose, a nitro sugar stereochemically homologous to D-desosamine.

296 In each case the 3-nitro sugars are obtained in pure form by crystallizatio

297 led the syntheses of an array of analogous 3-nitro sugars.

298 The undesirable nitro toxicophore could hypothetically be replaced by ot

299 e, whereas posaconazole (POS), and NTLA-1 (a nitro-triazole) cured approximately 90% and 20% of mice,

300 was reported to synthesize beta-amino alpha-nitro trifluoromethyl esters, precursors of alpha,beta-d