ライフサイエンスコーパス: nitro

1 ional groups such as ester, cyano, keto, and nitro.

2 3-Nitro-1,2,4-triazol-5-one (NTO) is an insensitive muniti

3 3-Nitro-1,2,4-triazol-5-one (NTO) is one of the main ingre

4 The reaction of 3-amino-5-nitro-1,2,4-triazole with nitrous acid produces the corr

5 It has also been found that 3-nitro-1,2-diphenylcyclopropene undergoes a nucleophilic

6 Some of the alpha-nitro-1,3-dicarbonyl intermediates exhibit enhanced reac

7 xymethylglycinate (SMG), 2-(hydroxymethyl)-2-nitro-1,3-propanediol (NT = nitrotriol), 2-nitro-1-propa

8 e reductive cyclization of the corresponding nitro-1,4-diketones.

9 of masked 2,3-diaminoindole 1 from 2-iodo-3-nitro-1-(phenylsulfonyl)indole (2) has been developed.

10 f the novel synthetic CB1 PAM, 6-methyl-3-(2-nitro-1-(thiophen-2-yl)ethyl)-2-phenyl-1H-indole (ZCZ011

11 2-nitro-1,3-propanediol (NT = nitrotriol), 2-nitro-1-propanol (NP)] against 5 different microbial pat

12 l for the efficient synthesis of (1-methyl-2-nitro-1H-imidazol-5-yl)methanol, which is a key intermed

13 can be converted into a range of 1-methyl-2-nitro-1H-imidazole-based precursors of bioreductive prod

14 ple consecutive 'non-standard' ( , 6-amino-5-nitro-2(1H)-pyridone, and , 2-amino-imidazo[1,2-a]-1,3,5

15 y with hydrophobic 4-(2-hydroxyethylamino)-7-nitro-2,1,3-benzoxadiazole (NBD) donors that occupy the

16 the samples were derivatized with 4-chloro-7-nitro-2,1,3-benzoxadiazole (NBD-Cl) prior to CE-UV analy

17 6-Nitro-2,3-dihydroimidazo[2,1-b][1,3]oxazole derivatives

18 roducts of HMX hydrolysis such as nitrite, 4-nitro-2,4-diazabutanal, formaldehyde, nitrous oxide, for

19 alues, because the anion channel inhibitor 5-nitro-2-(3-phenylpropylamino) benzoic acid decreased O(2

20 ,2-a]pyridines leading to the formation of 3-nitro-2-(arylvinyl)imidazo[1,2-a]pyridine derivatives.

21 oleoyl-sn-glycero-3-phosphoethanolamine-N-(7-nitro-2-1,3-benzoxadiazol-4-y l)], incorporated into a p

22 compounds 7 were prepared by reduction of 7-nitro-2-aryl-1,2-benzisoselenazol-3(2H)-ones 3 and 6 wit

23 aphy-free synthesis is the coupling of (R)-4-nitro-2-butanol and glyoxal (trimeric form) mediated by

24 oxymethyl-2-furaldehyde (5AMF), and methyl-5-nitro-2-furoate (M5NF), were analyzed for effects on wat

25 and three structurally related compounds, 5-nitro-2-furoic acid (5NFA), 5-acetoxymethyl-2-furaldehyd

26 e-Gly (fusion inhibitor peptide [FIP]) and 4-nitro-2-phenylacetyl amino-benzamide (AS-48) have simila

27 onjugated nitroalkene to give 2-alkyl/aryl-3-nitro-2H-chromenes in excellent enantioselectivity withi

28 rbonate, which affords in crystalline form 3-nitro-3,4,6-trideoxy-alpha-D-glucose, a nitro sugar ster

29 tituted amino acids (2S,3R,4S,5S)-1-methyl-4-nitro-3,5-diphenylpyrrolidine-2-carboxylic acid (endo-6)

30 c acid (endo-6) and (2S,3S,4R,5S)-1-methyl-4-nitro-3,5-diphenylpyrrolidine-2-carboxylic acid (exo-6),

31 yielded the primary explosive bis(4-diazo-5-nitro-3-oxopyrazolyl)methane (8), which showed superior

32 s were confirmed using biotinylated methyl-3-nitro-4-(piperidin-1-ylsulfonyl) benzoate (NPSB-B), a ch

33 Roxarsone (3-nitro-4-hydroxybenzenearsonic acid) is a pentavalent aro

34 s with nitrones to give highly substituted 4-nitro-4-isoxazolines in high yields.

35 s were treated with the protective drug 2-(2-nitro-4-trifluoromethylbenzoyl)-1, 3 cyclohexandione (NT

36 rescued by the administration of NTBC [2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione], a

37 e, this structurally related 7-substituted 2-nitro-5,6-dihydroimidazo[2,1-b][1,3]oxazine class was fu

38 Among the several modeled ligands, 3-nitro-5-((trifluoromethyl)sulfonyl)pyridine-2(1H)-one (L

39 enyl)-4H-1,2,4-triazole-3-thiols and their 3-nitro-5-(trifluoromethyl)phenyl analogues.

40 Among them, 2-[2-(3-methyl-4-nitro-5-isoxazolyl)vinyl]pyridine and 2-(benzylsulfonyl)

41 A McMurry-like reaction of a 2-(2-nitro-5-oxohexyl)pyrrole was employed to construct the s

42 antetheine arm into a mixed disulfide with 2-nitro-5-thiobenzoate ion (TNB(-)) activates this site to

43 ther applied to the system of irreversible 2-nitro-5-thiobenzoate oxidation used in the detection of

44 4,7-Dihydro-6-nitro-7-Ar-5-R-azolo[1,5-a]pyrimidines were obtained by

45 Substitution with hydroxy, cyano, nitro, acetamido, and fluoro led to high inhibitory acti

46 fluoride, chloride, trifluoromethyl, ester, nitro, acetate, cyanide, and ether groups.

47 g the molecules studied, which yielded gamma-nitro aldehydes in very high yields (up to 95%), with hi

48 al Michael-type addition of the imine to the nitro-alkene followed by a cyclization event.

49 Importantly, the nitro-alkylated peptides provide a new handle for site-s

50 ative asymmetric allylic alkylation of alpha-nitro allyl esters to afford acyclic tetrasubstituted ni

51 alence of the fluorinated reagent with alpha-nitro-alpha-diazo carbonyls was established.

52 m temperature to afford enantioenriched beta-nitro amines in good yields and high enantioselectivity,

53 A new series of nitro analogues of the duocarmycins was prepared and eva

54 gher ICL efficiency than the corresponding 2-nitro analogues.

55 at spans five different redox states between nitro and amine.

56 n of electron-withdrawing groups (EWGs) like nitro and cyano at the phenyl ring, leading to absorptio

57 ctron-withdrawing fluoro, chloro, ester, and nitro and electron-donating methyl, methoxy, dimethoxy,

58 -retardant metabolites, phenols, pesticides, nitro and nitroso compounds, and per- and polyfluoroalky

59 isomers recombined forming the corresponding nitro and nitroso compounds, and the most reactive cis/s

60 he carboxylate represented by a sulfonate or nitro and the thioester retained or represented by an es

61 ydes, ketones, esters, amides, phosphonates, nitro, and sulfur compounds was involved in the heterocy

62 onal groups, such as ester, ketone, nitrile, nitro, and triazene are well tolerated.

63 In this work, N-nitro- and N-nitroamino-functionalized mono- and bis(1,2

64 egantly exploited for selective detection of nitro aromatic compounds (NACs).

65 Phenolic and nitro-aromatic compounds are extremely toxic components

66 e saturation vapor pressures of phenolic and nitro-aromatic compounds are measured using Knudsen Effu

67 s was applied for the selective detection of nitro-aromatic compounds.

68 ed at 410nm and 625nm among the other tested nitro-aromatic compounds.

69 or other chemical compounds including common nitro-aromatic explosives and inorganic oxidative compou

70 nts in this study suggest these phenolic and nitro-aromatic will partition into the condensed state f

71 sed off-matrix was achieved using 4-fluoro-3-nitro-azidobenzene (FNAB) cross-linker.

72 ieved via azide group activity of 4-fluoro-3-nitro-azidobenzene (FNAB), which act as cross-linker and

73 ase detection and discrimination of multiple nitro-based explosives directly from collected air sampl

74 hly effective in the ultratrace detection of nitro-based explosives, under real-world conditions.

75 itive, selective, and multiplex detection of nitro-based explosives.

76 he acid/base-catalysed Kemp elimination of 5-nitro-benzisoxazole forming 2-cyano-4-nitrophenol has lo

77 uenga coupling between N-tosylhydrazones and nitro-benzyl bromide, followed by deoxygenation of ortho

78 tion of reactive oxygen species (ROS) with a nitro blue tetrazolium (NBT) assay.

79 n, the TCP-C60 film induced the reduction of nitro blue tetrazolium to diformazan in the presence of

80 of NOS promotes NADPH-dependent reduction of nitro-blue tetrazolium (NBT) to diformazan.

81 t promote NADPH-dependent reduction of tetra-nitro-blue tetrazolium (TNBT) in which all four phenolic

82 g peroxisome abundance using the small probe Nitro-BODIPY, which in vivo fluoresces selectively insid

83 ogen-bonding interactions and an interactive nitro chain in the crystal structure.

84 nerate a thiolate-ligated, nonheme iron(III)-nitro complex, [Fe(III)(NO2)(N3PyS)](+), which was chara

85 ed SBA sample is mixed with NaOH to obtain a nitro compound and the compound is then dripped onto the

86 nitriles) or into an amine (for instance, a nitro compound) in the presence of the same reducing age

87 y facile dealkylation to release the primary nitro compound.

88 ighting the differences in the metabolism of nitro compounds among mycobacterial species and emphasiz

89 t higher order hydrogen-bonded aggregates of nitro compounds and acids are the kinetically competent

90 ldehydes or ketones) with ammonia, amines or nitro compounds in the presence of suitable catalysts an

91 onyl and carboxylic derivatives, imines, and nitro compounds promoted by iron catalysts.

92 The reduction of nitro compounds to the corresponding amines is one of th

93 atic carboxylic acids to their corresponding nitro compounds using nitronium tetrafluoroborate and si

94 on non-noble 3d-metals for the reduction of nitro compounds using various reductants.

95 lyzing the transfer hydrogenation from AB to nitro compounds, leading to the green synthesis of quina

96 ectrochemical coupling of readily accessible nitro-compounds with benzyl alcohols to yield nitrone de

97 Nitro-conjugated linoleic acid (NO2-CLA) is preferential

98 ilic nitro-fatty acids (nitro-oleic acid and nitro-conjugated linoleic acid) potently activate SIRT6.

99 served, and competitive binding studies with nitro-containing additives suggest that 1,3-disiloxanedi

100 actants, a facile and selective reduction of nitro-containing aromatics and heteroaromatics can be ef

101 safe approach to highly valued reductions of nitro-containing compounds.

102 l-, aryl-, heteroaryl-, bromo-, chloro-, and nitro-containing diorgano dichalcogenides as coupling pa

103 lopropanes, functionalized with ester, keto, nitro, cyano etc.

104 ive functionality like acyl, alkoxycarbonyl, nitro, cyano, and even hydroxyl groups.

105 atalytic hydrogenation of the intermediate 4-nitro cycloadducts.

106 tions allowed the conversion of the obtained nitro derivative to a new scaffold of the type 3-aryl-1H

107 tile PAHs fluoranthene and pyrene into the 2-nitro derivatives 2-nitrofluoranthene and 2-nitropyrene

108 for the reduction of aromatic and aliphatic nitro-derivatives to amines has been investigated.

109 linearly with the dipole moments of chloro-, nitro- dichloro-, and dinitro- (o-, m-, and p-) benzene

110 ial species and emphasizing the potential of nitro drugs as antibacterials in various bacterial speci

111 sed, the corresponding syn-alpha-amino-gamma-nitro ester is obtained with almost complete enantiocont

112 alpha-Nitro esters and amides were obtained in good overall yi

113 had utilized this in the synthesis of alpha-nitro esters from nitroalkanes.

114 afe, rapid method for the synthesis of alpha-nitro esters via the trapping of nitronium ions.

115 the TL18 probe was explored for detection of nitro explosives.

116 nd employed as a fluorescent chemosensor for nitro explosives.

117 SO4(2-), and NO3(-)) at 100-fold ratios nor nitro-explosives of trinitrotoluene (TNT), hexahydro-1,3

118 binding of specific antibodies to respective nitro-explosives on a microtiter strip, resulting in the

119 icrotiter wells resulted in thermal lysis of nitro-explosives to generate nitrite ions.

120 ng thermally induced defragmentation of some nitro-explosives with a high degree of selectivity is re

121 rs, there has been an increasing interest in nitro fatty acids (NO2-FA) as signaling molecules formed

122 Binding of the nitro-fatty acid to the hydrophobic crevice of the SIRT6

123 t to determine whether OA-NO2 , an exemplary nitro-fatty acid, has the capacity to inhibit cutaneous

124 itional mechanism of SIRT6 activation by the nitro-fatty acid.

125 Herein we report that electrophilic nitro-fatty acids (nitro-oleic acid and nitro-conjugated

126 rated fatty acids give rise to electrophilic nitro-fatty acids (NO2 -FAs), such as nitro oleic acid (

127 Nitro-fatty acids (NO2-FAs) are the product of the react

128 Nitro-fatty acids are electrophilic anti-inflammatory me

129 Nitro-fatty acids are reactive signaling mediators that

130 Nitro-fatty acids can modify specific signaling pathways

131 One of the signaling cascades activated by nitro-fatty acids is the Keap1-Nrf2 pathway.

132 c islands coded for enzymes belonging to the Nitro-FMN-reductase superfamily.

133 er (18)O2 show that both oxygen atoms in the nitro function of CAM derive from O2.

134 he reaction proceeds through a PCET promoted nitro functional group transfer pathway.

135 A Zn/AcOH-mediated reduction of the nitro functionality followed by condensation onto benzal

136 Second, CO(2) fertilization and nitro gen deposition are the most important drivers of c

137 A denitration step renders the nitro group "traceless" and delivers secondary, tertiary

138 osine (3-NT) from Tyrosine (Tyr) by adding a nitro group (-NO2) with nitrating agents.

139 adiazole lead, carrying reduced forms of the nitro group and/or oxidized forms of a sulfur atom, disp

140 By implementation of both the azido and nitro group as sulfide-reactive functionalities on the s

141 Analogues substituted with a nitro group bind to mature amyloid fibrils, and the acti

142 e replacement of the potentially genotoxic 3-nitro group by 3-chloro and 3-fluoro substituents, resul

143 Reduction of the nitro group followed by derivatization of the so formed

144 Subsequent reduction of the nitro group followed by hydrolysis of the oxazoline ring

145 e a long history of use in therapeutics, the nitro group has toxicity issues and is often categorized

146 from energetically favorable stacking of the nitro group in with pi-electrons of the adjacent base.

147 Introduction of a para-nitro group into the benzene ring of the diene enabled s

148 This AAD process only occurred when a nitro group is bonded to the 4-position of the initial e

149 The nitro group is considered to be a versatile and unique f

150 n aryl-amine precursor (NH2-CAM) to the aryl-nitro group of CAM catalyzed by the non-heme diiron clus

151 measurements of the electro reduction of the nitro group of flunitrazepam at ca. -0.71 to -0.78 V vs.

152 moiety on one end of the car coupled with a nitro group on the other end.

153 Unique features include stacking of the nitro group on Z with the adjacent nucleobase ring in th

154 G:C pairs, perhaps to accommodate the large nitro group on Z.

155 9 was synthesized by (18)F displacement of a nitro group or an iodonium ylide.

156 imination occurred, leading to the selective nitro group reduction reaction on the syn-alpha-amino es

157 elopment for H2S detection include azide and nitro group reduction, nucleophilic attack, and CuS prec

158 Here we demonstrate that incorporation of a nitro group significantly stabilizes the LUMO, and hence

159 where an appropriate bioisostere replaced a nitro group that had a direct role in binding.

160 troarenes at a position ortho or para to the nitro group with formation of anionic sigma(H) adducts.

161 ration (i.e., the irreversible addition of a nitro group) of the Alzheimer-related peptide amyloid-be

162 e primary amine moiety is transformed into a nitro group).

163 leavages on the fatty acid backbone near the nitro group, allowing its localization within the FA aky

164 reducible functional groups such as alkenyl, nitro group, and even internal alkyne intact.

165 avior between pyrrolidines with or without a nitro group, demonstrating the strong nitro-group-depend

166 in place of an aromatic C-H bond (that is, a nitro group, halogen or boronic acid) and a subsequent f

167 Although a small number of drugs include the nitro group, it is generally not regarded as being "drug

168 uperior selectivity for hydrogenation of the nitro group, outperforming both conventional Pd nanopart

169 This reaction proceeds via reduction of the nitro group, resulting in in situ imine formation follow

170 h as a triazine, a ketone, an aldehyde, or a nitro group, were tolerated in these exchange reactions,

171 missive pai-conjugated enamines containing a nitro group, which generally behaves as strong quenchers

172 acids as inexpensive, readily available, and nitro group-free aminating reagents.

173 beta- and delta-carbons with respect to the nitro group.

174 Previously reported representatives bear a 3-nitro group.

175 The synthesis took advantage of efficient nitro-group reactions with the A/B/C ring skeleton const

176 ading the molecule either by dealkylation or nitro-group reduction have been identified.

177 e bond formation and aromatic/heteroaromatic nitro-group reductions represent two of the most commonl

178 sive and efficient procedure is outlined for nitro-group reductions, using industrial iron in the for

179 hout a nitro group, demonstrating the strong nitro-group-dependent periselectivity.

180 separately reduced both the para- and ortho-nitro groups and produced glycosylated products that acc

181 The nitro groups are involved in cation-cation and cation-io

182 gest that 1,3-disiloxanediols bind weakly to nitro groups but are strongly activating for catalysis.

183 Photoexcitation of nitro groups by a high-energy laser is not required; the

184 sibly because their less sterically hindered nitro groups can be released more easily as nitrite and

185 tivity to afford products with the vinyl and nitro groups cis to each other is observed with a 4-subs

186 is carried out in an (16)O2 atmosphere, CAM nitro groups contain both (18)O and (16)O, suggesting th

187 0.9), compounds containing halogen atoms or nitro groups gave a lower predicted ESI response.

188 In general, drugs containing nitro groups have been extensively associated with mutag

189 re, and evidence related to drugs containing nitro groups is rather contradictory.

190 The nitro groups of energetic compounds are readily reduced

191 It also reduced the nitro groups of Nit(V), forming p-aminophenyl arsenate (

192 bercular and antiparasitic agents containing nitro groups, along with a patent survey on hypoxia-acti

193 mples such as an olefin, a ketone, nitriles, nitro groups, and an aryl iodo substituent or a benzyl e

194 vey on hypoxia-activated prodrugs containing nitro groups, are also covered.

195 overs various aspects of agents that contain nitro groups, their bioreductive activation mechanisms,

196 ional groups, such as halogen, carbonyl, and nitro groups, underwent reaction with TMDS to give the c

197 and this is particularly true for aliphatic nitro groups.

198 ities, including ketone, alkene, alkyne, and nitro groups.

199 oms and the oxidation of nitrogen atoms into nitro groups.

200 ructure contains a tertiary amino group, two nitro-groups and a trifluoromethyl- group.

201 lopenta[b]indolines with versatile vinyl and nitro-groups.

202 hich yields amines and O(Bpin)(2), tolerates nitro, halide, and amino functional groups well, and thi

203 alcohols) functional group tolerance (amino, nitro, halo, alkoxy, thiomethoxy, and S- and N-heterocyc

204 e., cloaking) to the widely used 4-methoxy-7-nitro-indolinyl(MNI)-Glu probe prevented such off-target

205 rm skin sites: (i) control; (ii) 10 mm N(G) -nitro-l-arginine (l-NNA), a non-specific NOS inhibitor;

206 solution (Control), 400 nm ET-1, 10 mm N(G) -nitro-l-arginine (l-NNA; a NOS inhibitor) or a combinati

207 The NOS inhibitor N(G)-nitro-L-arginine methyl ester (L-NAME) administered afte

208 ffects and mechanism of action of Mb on N(G)-Nitro-L-arginine Methyl Ester (L-NAME) and Deoxycorticos

209 nd NOS inhibition in cancer cells using N(G)-nitro-l-arginine methyl ester (l-NAME), we demonstrate t

210 itutive nitric oxide synthase using N(omega)-nitro-L-arginine methyl ester (L-NAME)-recapitulates the

211 ed before and during NO inhibition (N(omega)-nitro-l-arginine methyl ester [L-NAME]).

212 N(omega)-Nitro-L-arginine methyl ester and 1H-[1,2,4]-oxadiazolo-

213 in the presence of the NOS inhibitors, N(G)-nitro-L-arginine methyl ester and aminoguanidine; in add

214 ypertensive challenges using either N(omega)-nitro-L-arginine methyl ester hydrochloride (L-NAME)/hig

215 The eNOS inhibitor N(G)-Nitro-l-arginine methyl ester mimicked anti-VEGF/VEGFR d

216 rsed the inhibitory effects of ADMA and N(G)-nitro-l-arginine methyl ester on inducible NOS (macropha

217 ed NOX4 expression was abrogated by N(omega)-nitro-l-arginine methyl ester, an inhibitor of NOS.

218 nitric oxide (NO) synthase inhibitor l-N (G)-nitro-l-arginine methyl ester, while iontophoresis of th

219 tion of nitric oxide synthase with N(omega) -nitro-l-arginine methyl ester.

220 ed by the nitric oxide synthase inhibitor NG-nitro-l-arginine methyl ester.

221 L-NAME (N(omega)-nitro-L-arginine methyl ester; nitric oxide synthase inh

222 of nitric oxide synthase via the inhibitor N-nitro-l-methyl-arginine ester.

223 ncharacterized enzymes exclusively produce 5-nitro-L-tryptophan, a previously unknown biosynthetic in

224 nstrate that adding a tyrosine derivative, 3-Nitro-L-tyrosine, into DMEM can mitigate the degradation

225 FAs), such as nitro oleic acid (OA-NO2 ) and nitro linoleic acid (LNO2 ).

226 ere, we examine the endogenous occurrence of nitro-linolenic acid (NO2-Ln) in Arabidopsis and the mod

227 r in vivo actions of these anti-inflammatory nitro-lipids.

228 elective addition of nitroalkanes to imines (nitro-Mannich reaction), mediated by an iron(II) catalys

229 cale through an asymmetric Michael addition, nitro-Mannich/lactamisation, Tsuji-Trost allylation, and

230 e privileged nature of a properly positioned nitro moiety on the 3-aryl group.

231 Contamination levels observed for the two nitro musks (musk xylene and musk ketone) are significan

232 developed procedure was applied to determine nitro musks in environmental water samples and was demon

233 analysis, was developed for the analysis of nitro musks in environmental water samples.

234 4-Nitro-N-[2-(2-phenylsulfanylethylamino)ethyl]benzamide h

235 2-Nitro-N-alkyl-N-(2-oxo-2-phenylethyl)benzenesulfonamide

236 Using N-methyl-N-nitro-N-nitroso-guanidine mutagenesis and selection, a m

237 eatment of DNA-methylating agent N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) and antimetabolite 6-thi

238 exposed to the alkylating agent N-methyl-N'-nitro-N-nitrosoguanidine (MNNG).

239 typic Sn1-type methylating agent N-methyl-N'-nitro-N-nitrosoguanidine.

240 fects of the PPARgamma antagonist 2-chloro-5-nitro-N-phenylbenzamide (GW9662) involving PPARdelta and

241 widely used PPARgamma antagonist 2-chloro-5-nitro-N-phenylbenzamide (GW9662).

242 Compounds with unsubstituted and nitro naphthalimide (1 and 2) show excellent selective f

243 Beginning with the nitro-NHC, we form an amine-NHC terminated surface, whic

244 r (NOM) significantly enhanced the yields of nitro/nitroso derivatives, likely via the production of

245 The formation of nitro/nitroso probe derivatives was evidenced by high-re

246 nched due to the electrophilic nature of the nitro (-NO2) groups on the TNT molecule.

247 A new and simple two-step SFODME using 4-nitro-o-phenylenediamine (4-NOPD) as a chelating agent w

248 ate that pretreatment of mice with 9- and 10-nitro-octadec-9-enoic acid (nitro-oleic acid, NO(2)-OA)

249 philic fatty acid nitroalkene derivative, 10-nitro-octadec-9-enoic acid (nitro-oleic acid, NO2-OA), w

250 BC) cells with the fatty acid nitroalkene 10-nitro-octadec-9-enoic acid (OA-NO(2)) in combination wit

251 nalogs of OA-NO(2), octadecanoic acid and 10-nitro-octadecanoic acid, did not react with Cys-319.

252 in rats, and allowed the identification of 4-nitro-octanedioic acid (NO2-8:0-diCOOH) as the most abun

253 ael reactions of a series of water-insoluble nitro-olefins in an aqueous medium.

254 In particular, 10-nitro oleic acid (10-NO2-OA) potently induces Nrf2-depen

255 philic nitro-fatty acids (NO2 -FAs), such as nitro oleic acid (OA-NO2 ) and nitro linoleic acid (LNO2

256 In contrast, the anti-inflammatory agent 10-nitro-oleic acid (NO2-OA), a component of the Mediterran

257 We have previously studied the effects of nitro-oleic acid (OA-NO2) on the human endothelial cell

258 report that electrophilic nitro-fatty acids (nitro-oleic acid and nitro-conjugated linoleic acid) pot

259 Importantly, treatment of cells with nitro-oleic acid promoted H3K9 deacetylation, whereas ol

260 e with 9- and 10-nitro-octadec-9-enoic acid (nitro-oleic acid, NO(2)-OA) significantly reduced the su

261 e derivative, 10-nitro-octadec-9-enoic acid (nitro-oleic acid, NO2-OA), were investigated in multiple

262 ng complication of premature birth caused by nitro-oxidative insult to the developing retinal vascula

263 and, in some cases, the formation of PAH and nitro-PAH compounds are discussed in detail, and suggest

264 ns are provided to minimize the formation of nitro-PAH compounds through aftertreatment design optimi

265 c aromatic hydrocarbon (PAH), and alkyl- and nitro-PAH emissions and assess their genotoxic potential

266 on of 4-Amino Phenol (AP), Phenol (Ph) and 4-Nitro Phenol (NP).

267 aditional chromogenic ELISA test employing p-nitro-phenyl phosphate (pNPP).

268 We previously reported that the bis-nitro-phenyl ROMK inhibitor VU591 exhibits voltage-depen

269 cussion about the nature, origin, or role of nitro phospholipids (NO2-PL) was reported up to now.

270 to afford tetrasubstituted alpha-amino-beta-nitro-phosphonates.

271 diesters (PMIDE) enables the synthesis of 1-nitro-PMIDE 10 and thus of azabenz-annulated perylene de

272 hesized by fluorination of the corresponding nitro precursor, followed by acidic removal of the 2-met

273 dation of an aryl-amine substrate to an aryl-nitro product catalyzed by the N-oxygenase CmlI in three

274 of an aryl-nitroso intermediate to the aryl-nitro product.

275 mitted to a new conservative treatment, the "Nitro-Push Blind Technique".

276 We selected the Escherichia coli nitro/quinone reductase NfsA for chloramphenicol detoxif

277 uction of TNT in the mitochondria, forming a nitro radical that reacts with atmospheric oxygen, gener

278 eroxide anion and hydroxyl radicals, organic nitro-radicals (ABTS, DPPH) and to inhibit lipid peroxid

279 The nitro reduction procedure will typically take 6-8 h to c

280 O as the catalyst with AgNO2 utilized as the nitro source as well as terminal oxidant in the presence

281 ode showed good stability in the presence of nitro species.

282 An NHC-catalyzed nitro-Stetter/elimination/Stetter reaction sequence empl

283 the primary amine moiety of STG, leading to nitro-STG (TP 437) (the primary amine moiety is transfor

284 These experiments confirmed that nitro-STG was formed as the main TP in the wastewater ma

285 Assessing nitro-stilbenoids, both approaches suggested nitrostilbe

286 rey-Chaykovsky cyclopropanation reactions of nitro styrenes.

287 remarkable enzyme-induced distortion of the nitro-substituent out of the plane of the phenyl ring by

288 udies indicated a crucial role for both meta-nitro substituents for antitubercular activity, while th

289 tuent and the number of electron-withdrawing nitro substituents.

290 wing groups like halides, carboxyesters, and nitro substituents.

291 lization of a partial positive charge on the nitro-substituted carbon in both transition state and pr

292 nitro substitution in the complete series of nitro-substituted octaethylporphyrins.

293 enylenes connected to oxazole, imidazole, or nitro-substituted pyrrole.

294 The nitro-substituted quinazolin-4(3 H)-one 2k inhibited NLR

295 tructural effects of an increasing degree of nitro substitution in the complete series of nitro-subst

296 rm 3-nitro-3,4,6-trideoxy-alpha-D-glucose, a nitro sugar stereochemically homologous to D-desosamine.

297 In each case the 3-nitro sugars are obtained in pure form by crystallizatio

298 led the syntheses of an array of analogous 3-nitro sugars.

299 was reported to synthesize beta-amino alpha-nitro trifluoromethyl esters, precursors of alpha,beta-d

300 A) pair for site-specific incorporation of 3-nitro-tyrosine could not outcompete near-cognate suppres