ライフサイエンスコーパス: nocifensive

1 lly reduces isocyanate- and tear gas-induced nocifensive behavior after both ocular and cutaneous exp

2 We show that TRPA1-mediated nocifensive behavior can be sensitized in vivo via PKA/P

3 t significantly potentiated capsaicin-evoked nocifensive behavior in female rats at proestrous and in

4 nically available compounds strongly reduced nocifensive behavior in mouse models of inflammatory and

5 urse of the MO-induced behavioral allodynia (nocifensive behavior in response to a previously innocuo

6 TRPA1-deficient mice show greatly reduced nocifensive behavior in response to isovelleral, indicat

7 herally selective dose of ACEA on MO-induced nocifensive behavior in vivo; and 3) the effects of five

8 ly inhibited ( approximately 40%) MO-induced nocifensive behavior in wild-type mice but not in TRPV1

9 urons, reduced meningeal blood flow, reduced nocifensive behavior induced by formalin injection or co

10 tween substance P levels and formalin-evoked nocifensive behavior may exist in diabetic rats, as exag

11 elease is unlikely to underlie the increased nocifensive behavior seen in diabetic rats.

12 of mechanical sensitivity of the abdomen and nocifensive behavior to electrical stimulation of the pa

13 ancreatic hyperalgesia was assessed by rat's nocifensive behavior to electrical stimulation of the pa

14 M1241-induced inhibition of capsaicin-evoked nocifensive behavior via peripheral actions is reversed

15 Formalin-evoked nocifensive behavior was increased in diabetic rats but

16 manner (EC(50) = 0.72 microg), and produced nocifensive behavior.

17 Noxious pH triggers pungent taste and nocifensive behavior.

18 on of the compound induced a TRPM3-dependent nocifensive behavior.

19 Pancreatic hyperalgesia was assessed by nocifensive behavioral response to electrical stimulatio

20 mined the role of the descending 5-HT in rat nocifensive behaviors after persistent pain by selective

21 receptor agonists induced similar levels of nocifensive behaviors and activity at spinal NMDA recept

22 cline reversed and prevented the increase of nocifensive behaviors and levels of P-p38 in rats with C

23 s a key regulator of the operating range for nocifensive behaviors and suggest strategies for produci

24 These nocifensive behaviors can be blocked by the NK1 antagoni

25 ged allodynia to hindpaw PGE(2) and enhanced nocifensive behaviors evoked by intrathecal mGluR1/5 ago

26 trations, menthol can induce lacrimation and nocifensive behaviors in a TRPM8 independent mechanism.

27 s to contribute to central sensitization and nocifensive behaviors in certain animal models of chroni

28 , to contribute substantially to paradoxical nocifensive behaviors in neonates and various pain state

29 Nocifensive behaviors induced by the intradermal injecti

30 these findings are associated with enhanced nocifensive behaviors specifically in TRPA1-dependent pa

31 of KET to reduce significantly a variety of nocifensive behaviors suggests that this clinically safe

32 injection of 100 microg anandamide produced nocifensive behaviors that were attenuated by pre-treatm

33 excited cutaneous C nociceptors and produced nocifensive behaviors via activation of TRPV1 receptors.

34 stration that exogenous peripheral SP causes nocifensive behaviors would seem to indicate that SP can

35 s the stimulus intensities that trigger such nocifensive behaviors, but the molecular networks that d

36 ght illumination of the skin produced robust nocifensive behaviors, evoked by the remote stimulation

37 crimation via TRPM8 channels without evoking nocifensive behaviors.

38 ociceptors by anandamide was associated with nocifensive behaviors.

39 vivo and if this excitation correlated with nocifensive behaviors.

40 enuation of both ongoing and movement-evoked nocifensive behaviors.

41 romedial medulla (RVM) neuronal activity and nocifensive behaviors.

42 nput, the neural signals trigger protective (nocifensive) behaviors, and the sensory stimuli that rea

43 in the head nociceptor neuron, ASH, we study nocifensive behaviour and Ca(2+) influx.

44 tionship between ion permeation and animals' nocifensive behaviour is unknown.

45 second phase of formalin-induced spontaneous nocifensive behaviour, suggesting a potential role of SO

46 on neurons and/or participating in segmental nocifensive circuits.

47 onic saline that evoked comparable levels of nocifensive eye wipe behaviors when applied to the ocula

48 lating the elaborate dendrite morphology and nocifensive functions of Drosophila larval class IV dend

49 analgesia and shifts the operating range for nocifensive heat avoidance to higher temperatures.

50 gnitude, suggesting that ON cells facilitate nocifensive motor reactions.

51 tion of either H(2)O(2) or 15d-PGJ2 evoked a nocifensive/pain response in wild-type mice, but not in

52 Nocifensive paw-shaking behavior following masseteric in

53 soup of inflammatory mediators enhanced the nocifensive paw-withdrawal reflex elicited by hypotonic

54 eurons (1) are not essential for determining nocifensive reflex responsiveness to noxious thermal sti

55 l of this study was to identify neurons with nocifensive reflex-related activity in the mesopontine t

56 The mesopontine tegmentum thus contains nocifensive reflex-related neurons with neurophysiologic

57 RVM produce changes in the latency of spinal nocifensive reflexes and, when iontophoretically applied

58 nd provide the afferent limb for hyperactive nocifensive reflexes.

59 in the formalin test: (1) increased baseline nocifensive responding and (2) reduced antinociceptive a

60 d to innocuous warming with regurgitation, a nocifensive response.

61 on caused scratching, biting, and licking, a nocifensive response.

62 In additional studies, nocifensive responses (eye swiping and lid closure) were

63 3(Lbx1) neurons): the mice lost brush-evoked nocifensive responses and conditional place aversion.

64 ment attenuated formalin-induced spontaneous nocifensive responses and tissue or nerve injury-induced

65 ly inhibited formalin- and capsaicin-induced nocifensive responses but did not alter baseline thermal

66 rents induced by CIM0216 in DRG neurons, and nocifensive responses elicited by this TRPM3 agonist in

67 ate well with the time course of behavioural nocifensive responses in rats to the same agonist descri

68 with other P2X channel agonists, can produce nocifensive responses in rodents.

69 ation, menthol (50 mM) increased tearing and nocifensive responses in TRPM8 wild type and knockout an

70 ments demonstrate that DC lesions reduce the nocifensive responses produced by noxious stimulation of

71 had no effect in TRPM8 knockout mice, while nocifensive responses remained unaffected.

72 ng pathway, were injured and then tested for nocifensive responses to a normally subnoxious stimulus.

73 injury-evoked hypersensitivity to cold, and nocifensive responses to cooling compounds.

74 these neurons in (1) normal baseline reflex nocifensive responses to noxious thermal stimulation (ho

75 role in the endogenous modulation of reflex nocifensive responses to persistent pain in the formalin

76 onses to punctate mechanical stimulation and nocifensive responses to thermal noxious stimuli are not

77 s demonstrated by increased capsaicin-evoked nocifensive responses, increased calcitonin gene-related

78 injection in mice reduces heat and capsaicin nocifensive responses, whereas the intra-articular injec

79 e emotional-affective behaviors and modulate nocifensive responses.

80 yphenylglycol) precipitated allodynia and/or nocifensive responses.

81 e in baseline tail-flick and hotplate reflex nocifensive responses.