ライフサイエンスコーパス: non-homologous

1 ences, 5-9% of alignments at iteration 5 are non-homologous.

2 ediction of STAR3D is more accurate for both non-homologous and homologous RNAs than other state-of-t

3 ocol can be successfully applied to pairs of non-homologous but functionally linked proteins to find

4 nks were observed involving the beta subunit non-homologous C-terminal tail, several cross-links were

5 ulatory GTPases, but is atypical in having a non-homologous, C-terminal domain of approximately 20 kD

6 se as mice, wheat and yeast, indicating that non-homologous centromere pairing in early meiosis and a

7 that early centromere pairing occurs between non-homologous centromeres.

8 ly to inhibit sustained interactions between non-homologous chromatids, and that these ectopic intera

9 to those observed in Cdk2 KO mice including non-homologous chromosome pairing, unrepaired double-str

10 nto a new region of the same chromosome or a non-homologous chromosome.

11 d chromatin bridges between the telomeres of non-homologous chromosomes in Atrecq4A at metaphase I, i

12 be compared with parameter distributions for non-homologous datasets of different classes of protein

13 Non-homologous DNA appears to divert cells towards error

14 deletion of genomic sequence or insertion of non-homologous DNA at the edited locus in a cell line sp

15 coni protein D2, ATM protein expression, and non-homologous DNA end joining protein expression and fu

16 2056 phosphorylation, indicative of elevated non-homologous DNA end joining.

17 Classical non-homologous DNA end-joining (NHEJ) is a major mammali

18 It is the main nuclease in the non-homologous DNA end-joining pathway (NHEJ).

19 ing site-specific nuclease digestion through non-homologous DNA end-joining, as opposed to single str

20 xtensive and persistent interactions between non-homologous DNAs.

21 n the neighboring sequence region contains a non-homologous domain, PSI-BLAST can incorporate the unr

22 ndant proteins and test it on a large set of non-homologous domains, as well as on the set of protein

23 ing partners promotes the rapid unbinding of non-homologous dsDNA and drives strand exchange forward

24 Non-homologous dsDNA rapidly unbinds, whereas homologous

25 ce that selection for RPS5 involves multiple non-homologous effectors and multiple pathogen species.

26 Non homologous end joining (NHEJ) is an important proces

27 The non homologous end-joining (NHEJ) pathway of double-stra

28 mosome fusions via the mutagenic alternative non-homologous end joining (A-NHEJ) pathway.

29 Alternative non-homologous end joining (alt-NHEJ) was originally ide

30 mpared to HR, whereas Ku-dependent classical non-homologous end joining (C-NHEJ) has a minimal role t

31 Classic non-homologous end joining (C-NHEJ) is the predominant D

32 ngly none of the components of the canonical non-homologous end joining (C-NHEJ) pathway were identif

33 Canonical non-homologous end joining (c-NHEJ) repairs DNA double-s

34 pair is usually facilitated by the classical non-homologous end joining (C-NHEJ), or homologous recom

35 Classical non-homologous end joining (cNHEJ) and homologous recomb

36 ndependent function for LRF in the classical non-homologous end joining (cNHEJ) pathway of double-str

37 Micro-homology-mediated non-homologous end joining (MMEJ) can also be used but t

38 There is increased DNA mis-repair by non-homologous end joining (NHEJ) and both NHEJ and homo

39 promotes the two major DSB repair pathways, non-homologous end joining (NHEJ) and homologous recombi

40 DNA non-homologous end joining (NHEJ) and homologous recombi

41 ebrafish (Danio rerio) and livestock through non-homologous end joining (NHEJ) and homology-directed

42 trand break repair that buttresses canonical non-homologous end joining (NHEJ) and is manifest in NHE

43 Homology-directed repair and non-homologous end joining (NHEJ) are the two major DSB

44 Mammalian cells require non-homologous end joining (NHEJ) for the efficient repa

45 The repair of DSBs by non-homologous end joining (NHEJ) has been extensively s

46 ohomology-mediated end joining (MMEJ), while non-homologous end joining (NHEJ) has not been reported.

47 Initiation of HR in the G1 phase blocks non-homologous end joining (NHEJ) impairing DSB repair.

48 DNA double-strand break (DSB) repair by non-homologous end joining (NHEJ) in human cells is init

49 Non-homologous end joining (NHEJ) involves limited proce

50 Non-homologous end joining (NHEJ) is a key cellular proc

51 Non-homologous end joining (NHEJ) is a major DNA double-

52 Non-homologous end joining (NHEJ) is a major pathway to

53 Non-homologous end joining (NHEJ) is critical for the ma

54 DNA double strand break (DSB) repair by non-homologous end joining (NHEJ) is initiated by DSB de

55 Non-homologous end joining (NHEJ) is the main repair pat

56 Non-homologous end joining (NHEJ) is the major model pro

57 m the RAG post-cleavage complex (PCC) to the non-homologous end joining (NHEJ) machinery to promote a

58 are non-recurrent and can be generated by a non-homologous end joining (NHEJ) mechanism.

59 capabilities; however, the preponderance of non-homologous end joining (NHEJ) mediated repair events

60 The available evidence indicates a role for non-homologous end joining (NHEJ) of DNA double-strand b

61 We hypothesize that inhibiting non-homologous end joining (NHEJ) or enhancing homology-

62 regulated process performed predominantly by non-homologous end joining (NHEJ) or homologous recombin

63 and breaks (DSBs) are repaired by either the non-homologous end joining (NHEJ) or homologous recombin

64 uble strand breaks (DSBs) can be repaired by non-homologous end joining (NHEJ) or homology-directed r

65 implicates breaks followed by repair through non-homologous end joining (NHEJ) or stalled fork repair

66 se IIIalpha is a component of an alternative non-homologous end joining (NHEJ) pathway for DNA double

67 The non-homologous end joining (NHEJ) pathway is used in div

68 referentially repaired using the error-prone non-homologous end joining (NHEJ) pathway.

69 R) while stymieing repair by the error-prone non-homologous end joining (NHEJ) pathway.

70 f microhomology in both alt-EJ and classical non-homologous end joining (NHEJ) remains unclear.

71 Inhibition of Non-Homologous End Joining (NHEJ) repair either pharmaco

72 B-mediated homologous recombination (HR) and non-homologous end joining (NHEJ) repair systems, leadin

73 ught to arise from a moderate attenuation of non-homologous end joining (NHEJ) repair, the role of DE

74 Non-homologous end joining (NHEJ) repairs DNA double str

75 knockout MEFs exhibited distinct defects in non-homologous end joining (NHEJ) when compared to their

76 Here, we suggest a role of LKB1 in non-homologous end joining (NHEJ), a major DNA double-st

77 nit (DNA-PKcs) plays a key role in mediating non-homologous end joining (NHEJ), a major repair pathwa

78 Non-allelic homologous recombination (NAHR), non-homologous end joining (NHEJ), and microhomology-med

79 otes, DNA DSBs are predominantly repaired by non-homologous end joining (NHEJ), but DNA ends can also

80 for sequence-specific gene knockout through non-homologous end joining (NHEJ), but it remains ineffi

81 ir factors, in particular those required for non-homologous end joining (NHEJ), do not form discrete

82 non-allelic homologous recombination (NAHR), non-homologous end joining (NHEJ), fork stalling and tem

83 hen can become the substrate for error-prone non-homologous end joining (NHEJ), generating mutations

84 xcision repair (NER), mismatch repair (MMR), non-homologous end joining (NHEJ), homologous recombinat

85 Yeast Rap1 protects telomeres from non-homologous end joining (NHEJ), plays important roles

86 common DSB repair mechanism in human cells, non-homologous end joining (NHEJ), rejoins broken DNA en

87 In contrast to non-homologous end joining (NHEJ), TMEJ efficiently repa

88 air by homologous recombination (HR) but not non-homologous end joining (NHEJ), using HeLa cell lines

89 s of either homologous recombination (HR) or non-homologous end joining (NHEJ), whereas SUMO2/3 was r

90 s, homology-directed recombination (HDR) and non-homologous end joining (NHEJ).

91 switch recombination (CSR), are repaired by non-homologous end joining (NHEJ).

92 bition induces a repair defect that involves non-homologous end joining (NHEJ).

93 repair from homologous recombination (HR) to non-homologous end joining (NHEJ).

94 itical for their proper joining by classical non-homologous end joining (NHEJ).

95 karyotic cells are predominantly repaired by non-homologous end joining (NHEJ).

96 role in double-strand break (DSB) repair by non-homologous end joining (NHEJ).

97 for DSB repair: homologous recombination and non-homologous end joining (NHEJ).

98 CC4 (LX) complex, which functions during DNA non-homologous end joining (NHEJ).

99 y involving homologous recombination (HR) or non-homologous end joining (NHEJ).

100 inase, accumulate 53BP1 and are processed by non-homologous end joining (NHEJ).

101 pair DSBs: homologous recombination (HR) and non-homologous end joining (NHEJ).

102 that support single-strand break repair and non-homologous end joining (NHEJ).

103 ch between homologous recombination (HR) and non-homologous end joining (NHEJ).

104 A repair: homology directed repair (HDR) and non-homologous end joining (NHEJ).

105 nt, while still protecting telomeres against non-homologous end joining (NHEJ).

106 DSBs), thereby influencing the efficiency of non-homologous end joining (NHEJ).

107 . patens mutants for DSB factors involved in non-homologous end joining (NHEJ).

108 t provides DNA ligase activity for classical non-homologous end joining (the predominant DNA double-s

109 that errors in DNA repair pathways, such as non-homologous end joining and homologous recombination,

110 The TRF2-Rap1 complex suppresses non-homologous end joining and interacts with DNAPK-C to

111 e other five types of solid tumors, in which non-homologous end joining and microhomology end joining

112 ted stochastic model of DNA damage repair by non-homologous end joining and of gamma irradiation-indu

113 otein and combined deficiencies in classical non-homologous end joining and p53 predispose to RAG-ini

114 e found that MMSET is required for efficient non-homologous end joining as well as homologous recombi

115 ssay that is more sensitive than the typical non-homologous end joining assay.

116 RNF168 rescues 53BP1 recruitment involved in non-homologous end joining but not BRCA1 recruitment for

117 the interference of high LET radiation with non-homologous end joining but not homologous recombinat

118 roach to reduce the toxicity associated with non-homologous end joining by promoting the use of homol

119 de DNA end binding proteins required for the non-homologous end joining DNA repair pathway, increases

120 ation (insertion or deletion) by error-prone non-homologous end joining DNA repairing.

121 We found Cas9-gRNA achieved 7-8x higher non-homologous end joining efficiencies (3%) than reTALE

122 fragment at the same time, thereby reducing non-homologous end joining efficiency.

123 t acetylation of H4 regulates binding of the non-homologous end joining factor 53BP1, which engages c

124 G2 shepherd the broken DNA ends to classical non-homologous end joining for proper repair, roles for

125 ting functional redundancy between Rad18 and non-homologous end joining for tolerance of oxidative DN

126 ination (HR) and antagonizes 53BP1-dependent non-homologous end joining in S/G2 phase.

127 Repair of DNA double-strand breaks (DSBs) by non-homologous end joining is critical for neural develo

128 A-dependent protein kinase (DNA-PK)-mediated non-homologous end joining is inhibited.

129 Non-homologous end joining is initiated by the associati

130 repair (HR), while counteracting error-prone non-homologous end joining of DNA double-strand breaks.

131 poration, and it efficiently participates in non-homologous end joining of double-strand DNA breaks.

132 7 or its adapters impairs Ku80 removal after non-homologous end joining of DSBs.

133 ther demonstrate that the excursions promote non-homologous end joining of dysfunctional telomeres an

134 derived hiPSCs where successful deletion and non-homologous end joining of up to 725 kb reframed the

135 SceI-induced break can be repaired either by non-homologous end joining or by recombination between t

136 A double-strand breaks can be eliminated via non-homologous end joining or homologous recombination.

137 s in a G1-like DNA repair mode which favours non-homologous end joining over interchromosomal recombi

138 double-strand DNA break (DSB) repair via the non-homologous end joining pathway, as unrepaired DSBs a

139 DNA-PKcs, which is integral to the non-homologous end joining pathway, thus negatively regu

140 an be further improved by suppression of the non-homologous end joining pathway.

141 uble strand breaks, initiating repair by the non-homologous end joining pathway.

142 B) repair as the underlying mechanism of the non-homologous end joining pathway.

143 h recombination use overlapping but distinct non-homologous end joining pathways to repair DNA double

144 r shown to have homologous recombination and non-homologous end joining related activities and also t

145 led to enhanced phosphorylation of DNA-PK, a non-homologous end joining repair protein, in Hec-108 ce

146 removal of histone H3 from the genome during non-homologous end joining was promoted by both ATM and

147 EGFR mutation is associated with a defect in non-homologous end joining, a major pathway for DNA doub

148 ecombination, an error-free mechanism, or by non-homologous end joining, a process susceptible to int

149 ctionally contribute to efficient resection, non-homologous end joining, and tolerance to DNA-damagin

150 lta defects in Tel1/ATM kinase signaling and non-homologous end joining, consistent with the role of

151 ile another chromosome break repair pathway, non-homologous end joining, does not affect chromosome s

152 the processing of dysfunctional telomeres by non-homologous end joining, putatively through stabiliza

153 at take part in homologous recombination and non-homologous end joining, respectively, were transcrip

154 A DSB repair by homologous recombination and non-homologous end joining, respectively.

155 damage-tolerance in G(1) (because of back-up non-homologous end joining-mediated DSB repair), yet Rad

156 e heterodimer Ku70/Ku80, has a major role in non-homologous end joining-the main pathway in mammals u

157 sed G overhang levels, and altered levels of non-homologous end joining.

158 repair by both homologous recombination and non-homologous end joining.

159 s of double-strand break repair generated by non-homologous end joining.

160 equent repair by homologous recombination or non-homologous end joining.

161 r repairing DNA double-strand breaks through non-homologous end joining.

162 s: homologous recombination and Ku-dependent non-homologous end joining.

163 gy near the breakpoints resembling repair by non-homologous end joining.

164 ends that are poor substrates for classical non-homologous end joining.

165 dent on Ku70/80 and LIG4, or the alternative non-homologous end-joining (A-NHEJ), which relies on PAR

166 Classical non-homologous end-joining (C-NHEJ) is the dominant path

167 elomere fusions require either the classical non-homologous end-joining (C-NHEJ) pathway dependent on

168 Besides the KU-dependent classical non-homologous end-joining (C-NHEJ) pathway, an alternat

169 ng mechanisms, the main process is classical non-homologous end-joining (C-NHEJ) which relies on Ku b

170 or critical role in ICL repair was seen for non-homologous end-joining (cku-80) or base excision rep

171 CC4-like factor (XLF) functions in classical non-homologous end-joining (cNHEJ) but is dispensable fo

172 Non-homologous end-joining (NHEJ) and homologous recombi

173 Non-homologous end-joining (NHEJ) and homologous recombi

174 s) are repaired by two principal mechanisms: non-homologous end-joining (NHEJ) and homologous recombi

175 e repair of DNA double-strand breaks (DSBs): non-homologous end-joining (NHEJ) and homologous recombi

176 ase II (TOP2) are rejoined by TDP2-dependent non-homologous end-joining (NHEJ) but whether this promo

177 TRADD facilitates non-homologous end-joining (NHEJ) by recruiting NHEJ rep

178 tional error-prone pathway of DSB repair via non-homologous end-joining (NHEJ) catalysed by Ku and DN

179 to be associated with the components of the non-homologous end-joining (NHEJ) complex and participat

180 rate that combined inactivation of the XRCC4 non-homologous end-joining (NHEJ) DNA repair gene and p5

181 Allele-specific gene disruption induced by non-homologous end-joining (NHEJ) DNA repair offers a po

182 As the non-homologous end-joining (NHEJ) factor, Ku70/80 (Ku),

183 Non-homologous end-joining (NHEJ) is a critical error-pr

184 chanisms for DSB repair; in mammalian cells, non-homologous end-joining (NHEJ) is a major DSB repair

185 Non-homologous end-joining (NHEJ) is the most prominent

186 The alternative non-homologous end-joining (NHEJ) machinery facilitates

187 ge response pathways, and promotes efficient non-homologous end-joining (NHEJ) of dysfunctional telom

188 DSBs are repaired by either error prone non-homologous end-joining (NHEJ) or error-free homologo

189 the X family that has been implicated in the non-homologous end-joining (NHEJ) pathway during repair

190 y (CHO) cell lines that are defective in the non-homologous end-joining (NHEJ) pathway of DNA double-

191 The non-homologous end-joining (NHEJ) pathway repairs DNA do

192 DNA fragments, which are not repaired by the non-homologous end-joining (NHEJ) pathway.

193 depleting HP1 from cells did not affect the non-homologous end-joining (NHEJ) pathway: instead it el

194 ed via the single-strand annealing (SSA) and non-homologous end-joining (NHEJ) pathways in a manner d

195 osomes and generate genome rearrangements by non-homologous end-joining (NHEJ) processes in specializ

196 dation of a novel assay to measure mutagenic non-homologous end-joining (NHEJ) repair in living cells

197 In contrast, alleles created by non-homologous end-joining (NHEJ) repair of double-stran

198 NA breaks are processed and repaired via the non-homologous end-joining (NHEJ) repair pathway.

199 homology directed repair (HDR) and decreased non-homologous end-joining (NHEJ) repair, suggesting tha

200 efficiency, which are typically repaired by non-homologous end-joining (NHEJ) resulting in nonspecif

201 a DNA nuclease that plays important roles in non-homologous end-joining (NHEJ), a major double-strand

202 Here we report a novel role of non-homologous end-joining (NHEJ), a pathway of double-s

203 Non-homologous end-joining (NHEJ), a repair process pred

204 n (HR) repair with a concomitant decrease in non-homologous end-joining (NHEJ), accounting for the im

205 Metnase promotes non-homologous end-joining (NHEJ), and knockdown causes

206 syl-DNA phosphodiesterase 2 (TDP2)-dependent non-homologous end-joining (NHEJ), but whether this proc

207 DNA-PKcs; encoded by PRKDC) functions in DNA non-homologous end-joining (NHEJ), the major DNA double

208 Since mammalian cells can repair DSBs by non-homologous end-joining (NHEJ), we hypothesized that

209 Finally, we extend this non-homologous end-joining (NHEJ)-based technique by dir

210 ever, mutagenic events caused by error-prone non-homologous end-joining (NHEJ)-mediated repair are in

211 NA damage being channelled through repair by non-homologous end-joining (NHEJ).

212 trand break (DSB) repair pathways, including non-homologous end-joining (NHEJ).

213 repaired predominantly in mammalian cells by non-homologous end-joining (NHEJ).

214 tic opening before their repair by classical non-homologous end-joining (NHEJ).

215 DNA double-strand breaks (DSBs) repaired by non-homologous end-joining (NHEJ).

216 )p53(-/-) MEFs, homologous recombination and non-homologous end-joining activities were significantly

217 revious studies have shown that 53BP1 is pro-non-homologous end-joining and anti-HR.

218 timated frequencies of accurate or mutagenic non-homologous end-joining and gene correction by homolo

219 ks between the target sequences, stimulating non-homologous end-joining and homologous recombination.

220 mulation at DNA breaks is enhanced by active non-homologous end-joining but does not require DNA-PKcs

221 estigate the interplay between Ku, a central non-homologous end-joining component, and the Mre11-Rad5

222 protein NONO was found to be involved in the non-homologous end-joining DNA repair process and in pol

223 ns indicate that these have been mediated by non-homologous end-joining DNA repair, although varying

224 sh that REV7 blocks DSB resection to promote non-homologous end-joining during immunoglobulin class s

225 We find that inversion depends on the non-homologous end-joining enzyme LIG4.

226 e the persistence of random integrations and non-homologous end-joining events.

227 Hypomorphic mutations in the non-homologous end-joining gene DCLRE1C (encoding ARTEMI

228 (DNA-PK), a crucial player in DNA repair by non-homologous end-joining in higher eukaryotes, consist

229 e repaired with a high level of precision by non-homologous end-joining in mammalian cells.

230 demonstrate the importance of TDP2-dependent non-homologous end-joining in protecting both gene trans

231 bioluminescence imaging, that the assay for non-homologous end-joining is sensitive, quantitative, r

232 SWI/SNF and RSC enzymes is inhibited by the non-homologous end-joining machinery, and that their rec

233 DSBs are repaired by non-homologous end-joining or homology directed repair (

234 tid means that repair of DSBs occurs through non-homologous end-joining or microhomology-mediated end

235 s expressing BCR-ABL1 utilize an alternative non-homologous end-joining pathway (ALT NHEJ) to repair

236 leotides during gap-filling synthesis in the non-homologous end-joining pathway of double-strand brea

237 As a member of the non-homologous end-joining pathway, it is also involved

238 ch as those encountered by pol lambda in the non-homologous end-joining pathway, may have been solved

239 in the proximity of the break were due to a non-homologous end-joining pathway, while larger deletio

240 in repairing DNA double-strand breaks by the non-homologous end-joining pathway.

241 telomeres to protect them from engaging the non-homologous end-joining pathway.

242 This overexpression triggers SSB repair and non-homologous end-joining pathways to increase DNA repa

243 Wnt signalling enhances non-homologous end-joining repair in CRC, which is media

244 Although DNA non-homologous end-joining repairs most DNA double-stran

245 a novel component regulating the switch from non-homologous end-joining to homologous recombination.

246 double-strand break repair switches from DNA non-homologous end-joining to homologous recombination.

247 in the repair of DNA double-strand breaks by non-homologous end-joining, and by the discovery of a un

248 breakpoint junctions revealed signatures of non-homologous end-joining, non-allelic homologous recom

249 involved defective base excision repair and non-homologous end-joining, pathways required for repair

250 epaired by homologous recombination (HR) and non-homologous end-joining.

251 pe repair mechanism of hairpin formation and non-homologous end-joining.

252 nts now stemming from other repeats and from non-homologous end-joining.

253 participate in homologous recombination and non-homologous end-joining.

254 echanisms, homologous-recombination (HR) and non-homologous-end-joining (NHEJ).

255 hat is distinct from that found in classical non-homologous-end-joining-, H2ax-, Mdc1- and Atm-defici

256 nferred when structurally distinct and hence non-homologous enzymes show the ability to catalyze the

257 f chromosomal DNA or insertion of 18 bp, and non-homologous flanking sequences were also processed.

258 from head-to-head and head-to-tail oriented "non-homologous" FRT partners are a 4-noded knot and a 5-

259 vC syndrome) led us to study the role of two non-homologous genes, EVC and LBN, in heart development

260 the other hand, N-glycan structures found on non-homologous glycoproteins do not show significant glo

261 The observed non-homologous interactions require the induction of pro

262 on a large-scale benchmark set of 205 x 3897 non-homologous multiple-chain complex pairs.

263 ) N-linked glycan library and PDB homologous/non-homologous N-glycoprotein sets indicate that GS-alig

264 In contrast, breakpoints associated with non-homologous (NH) mechanisms often have sequence micro

265 nation defects and frequently associate with non-homologous partners, instead of pairing with their p

266 n different organs, formed from sequentially non-homologous polypeptide chains and affecting human or

267 large scale, DSB formation is suppressed on non-homologous portions of the sex chromosomes via the D

268 to double-stranded DNA, and a suppression of non-homologous primer annealing and nonspecific amplific

269 reconstructions of TCPM mutants in which the non-homologous proteins are individually deleted, we pro

270 Non-homologous proteins in the T4aPM and TCPM are found

271 ket database to predict binding ligand of 75 non-homologous proteins that bind one of seven different

272 othelial cell loss of KRIT1, CCM2 or PDCD10, non-homologous proteins that form an adaptor complex.

273 possible to discriminate within a dataset of non-homologous proteins those that bind similar ligands

274 on specific scoring matrix, which then finds non-homologous proteins with significant expectation val

275 proteins, such as BigH1, or even unrelated, non-homologous proteins, such as Elba2.

276 separating training and test mutations from non-homologous proteins, which reflects inherent correla

277 method to a cognate-ligand bound dataset of non-homologous proteins.

278 ulators share no more sequence identity than non-homologous proteins.

279 sis and robustness tests, we create a set of non-homologous, purely synthetic, minimal promoters for

280 ydrolase family GH30) and then applied it to non-homologous (putative) retaining beta-glucosidases ca

281 dsDNA molecule allows dsDNA to extend along non-homologous Rad51-ssDNA filaments and remain stably b

282 by driving the swift unbinding of dsDNA from non-homologous Rad51-ssDNA filaments, while at the same

283 e normally unstable binding of that dsDNA to non-homologous RecA-ssDNA filaments, whereas pulling on

284 efficiency of both homologous and the other non-homologous recombination, as well as increases sensi

285 AST makes two types of errors: alignments to non-homologous regions and HOE alignments that begin in

286 d mechanism involving template switching and non-homologous repair mediates the formation of balanced

287 ts a shift in emphasis for new entries, from non-homologous representatives covering EC reaction spac

288 However, inclusion of non-homologous sequence segments into a profile causes i

289 o the point of giving complete alignments of non-homologous sequences, Stemloc-AMA aligns only sequen

290 itial 8 bp test to rapidly reject almost all non-homologous sequences.

291 Overextended alignments include non-homologous sequences; they occur most frequently bet

292 ce multiple clusters constituting unrelated (non-homologous) sequences.

293 all-to-all gapless structural match on 6684 non-homologous single-domain proteins in the PDB and fou

294 Here we find that non-homologous single-stranded DNA greatly stimulates Ca

295 the second end must be processed to remove a non-homologous tail before completing repair by gene con

296 tes on both strands, demonstrating that this non-homologous tail remains flexible and forms heterogen

297 Msh2-Msh3 is also required for 3' non-homologous tail removal (3' NHTR) in double-strand b

298 oupling a microhomology search to removal of non-homologous tails and microhomology-primed synthesis

299 the structures of serine hydrolases that are non-homologous to FAAH, such as elastase, trypsin, or ch

300 cular dynamics simulations performed on nine non-homologous viral protein structures and from variati