ライフサイエンスコーパス: non-homologous end-joining

1 sed G overhang levels, and altered levels of non-homologous end joining.

2 repair by both homologous recombination and non-homologous end joining.

3 s of double-strand break repair generated by non-homologous end joining.

4 equent repair by homologous recombination or non-homologous end joining.

5 r repairing DNA double-strand breaks through non-homologous end joining.

6 s: homologous recombination and Ku-dependent non-homologous end joining.

7 egulates the alternative DSB repair pathway, non-homologous end joining.

8 organisms by homologous recombination or by non-homologous end joining.

9 gy near the breakpoints resembling repair by non-homologous end joining.

10 repair by both homologous recombination and non-homologous end joining.

11 rotein results in a compensatory increase in non-homologous end joining.

12 maintenance and DNA repair by the pathway of non-homologous end joining.

13 ends that are poor substrates for classical non-homologous end joining.

14 epaired by homologous recombination (HR) and non-homologous end-joining.

15 pe repair mechanism of hairpin formation and non-homologous end-joining.

16 nts now stemming from other repeats and from non-homologous end-joining.

17 participate in homologous recombination and non-homologous end-joining.

18 de excision repair, telomere maintenance and non-homologous end-joining.

19 alker A mutations also cause a deficiency in non-homologous end-joining.

20 r repairing double stranded breaks in DNA is non-homologous end-joining.

21 mosome fusions via the mutagenic alternative non-homologous end joining (A-NHEJ) pathway.

22 dent on Ku70/80 and LIG4, or the alternative non-homologous end-joining (A-NHEJ), which relies on PAR

23 EGFR mutation is associated with a defect in non-homologous end joining, a major pathway for DNA doub

24 ecombination, an error-free mechanism, or by non-homologous end joining, a process susceptible to int

25 )p53(-/-) MEFs, homologous recombination and non-homologous end-joining activities were significantly

26 Non-homologous end joining also was triggered by etoposi

27 Alternative non-homologous end joining (alt-NHEJ) was originally ide

28 Deficiencies in non homologous end joining and mismatch repair do not in

29 that errors in DNA repair pathways, such as non-homologous end joining and homologous recombination,

30 Eukaryotic cells repair DSBs by both non-homologous end joining and homologous recombination.

31 The TRF2-Rap1 complex suppresses non-homologous end joining and interacts with DNAPK-C to

32 e other five types of solid tumors, in which non-homologous end joining and microhomology end joining

33 ted stochastic model of DNA damage repair by non-homologous end joining and of gamma irradiation-indu

34 otein and combined deficiencies in classical non-homologous end joining and p53 predispose to RAG-ini

35 revious studies have shown that 53BP1 is pro-non-homologous end-joining and anti-HR.

36 timated frequencies of accurate or mutagenic non-homologous end-joining and gene correction by homolo

37 tch recombination, homologous recombination, non-homologous end-joining and genome fragile sites all

38 ks between the target sequences, stimulating non-homologous end-joining and homologous recombination.

39 te the repair of DNA double-strand breaks by non-homologous end-joining and provide a conceptual fram

40 gulation, that BCCIP is unlikely to regulate non-homologous end joining, and that BCCIP plays a criti

41 ctionally contribute to efficient resection, non-homologous end joining, and tolerance to DNA-damagin

42 in the repair of DNA double-strand breaks by non-homologous end-joining, and by the discovery of a un

43 ts reveals both homologous recombination and non-homologous end joining as causative mechanisms.

44 e found that MMSET is required for efficient non-homologous end joining as well as homologous recombi

45 ssay that is more sensitive than the typical non-homologous end joining assay.

46 RNF168 rescues 53BP1 recruitment involved in non-homologous end joining but not BRCA1 recruitment for

47 the interference of high LET radiation with non-homologous end joining but not homologous recombinat

48 mulation at DNA breaks is enhanced by active non-homologous end-joining but does not require DNA-PKcs

49 roach to reduce the toxicity associated with non-homologous end joining by promoting the use of homol

50 ous recombination in one arm, accompanied by non-homologous end-joining by the other arm of the vecto

51 mpared to HR, whereas Ku-dependent classical non-homologous end joining (C-NHEJ) has a minimal role t

52 Classic non-homologous end joining (C-NHEJ) is the predominant D

53 In mammalian cells, the 'classical' non-homologous end joining (C-NHEJ) pathway repairs both

54 ngly none of the components of the canonical non-homologous end joining (C-NHEJ) pathway were identif

55 Canonical non-homologous end joining (c-NHEJ) repairs DNA double-s

56 pair is usually facilitated by the classical non-homologous end joining (C-NHEJ), or homologous recom

57 Classical non-homologous end-joining (C-NHEJ) is the dominant path

58 elomere fusions require either the classical non-homologous end-joining (C-NHEJ) pathway dependent on

59 Besides the KU-dependent classical non-homologous end-joining (C-NHEJ) pathway, an alternat

60 ng mechanisms, the main process is classical non-homologous end-joining (C-NHEJ) which relies on Ku b

61 or critical role in ICL repair was seen for non-homologous end-joining (cku-80) or base excision rep

62 Classical non-homologous end joining (cNHEJ) and homologous recomb

63 ndependent function for LRF in the classical non-homologous end joining (cNHEJ) pathway of double-str

64 CC4-like factor (XLF) functions in classical non-homologous end-joining (cNHEJ) but is dispensable fo

65 estigate the interplay between Ku, a central non-homologous end-joining component, and the Mre11-Rad5

66 lta defects in Tel1/ATM kinase signaling and non-homologous end joining, consistent with the role of

67 sensitivity of haematopoietic stem cells to non-homologous end-joining deficiency is therefore a key

68 de DNA end binding proteins required for the non-homologous end joining DNA repair pathway, increases

69 ation (insertion or deletion) by error-prone non-homologous end joining DNA repairing.

70 protein NONO was found to be involved in the non-homologous end-joining DNA repair process and in pol

71 ns indicate that these have been mediated by non-homologous end-joining DNA repair, although varying

72 ns are involved in homologous recombination, non-homologous end-joining, DNA damage checkpoint signal

73 ile another chromosome break repair pathway, non-homologous end joining, does not affect chromosome s

74 sh that REV7 blocks DSB resection to promote non-homologous end-joining during immunoglobulin class s

75 We found Cas9-gRNA achieved 7-8x higher non-homologous end joining efficiencies (3%) than reTALE

76 fragment at the same time, thereby reducing non-homologous end joining efficiency.

77 We find that inversion depends on the non-homologous end-joining enzyme LIG4.

78 e the persistence of random integrations and non-homologous end-joining events.

79 t acetylation of H4 regulates binding of the non-homologous end joining factor 53BP1, which engages c

80 form hybrid joints in vivo in the absence of non-homologous end-joining factors, we show that the ful

81 G2 shepherd the broken DNA ends to classical non-homologous end joining for proper repair, roles for

82 ting functional redundancy between Rad18 and non-homologous end joining for tolerance of oxidative DN

83 Hypomorphic mutations in the non-homologous end-joining gene DCLRE1C (encoding ARTEMI

84 hat is distinct from that found in classical non-homologous-end-joining-, H2ax-, Mdc1- and Atm-defici

85 ination (HR) and antagonizes 53BP1-dependent non-homologous end joining in S/G2 phase.

86 (DNA-PK), a crucial player in DNA repair by non-homologous end-joining in higher eukaryotes, consist

87 e repaired with a high level of precision by non-homologous end-joining in mammalian cells.

88 demonstrate the importance of TDP2-dependent non-homologous end-joining in protecting both gene trans

89 Repair of DNA double-strand breaks (DSBs) by non-homologous end joining is critical for neural develo

90 A-dependent protein kinase (DNA-PK)-mediated non-homologous end joining is inhibited.

91 Non-homologous end joining is initiated by the associati

92 bioluminescence imaging, that the assay for non-homologous end-joining is sensitive, quantitative, r

93 SWI/SNF and RSC enzymes is inhibited by the non-homologous end-joining machinery, and that their rec

94 damage-tolerance in G(1) (because of back-up non-homologous end joining-mediated DSB repair), yet Rad

95 chanism for the direct involvement of ATM in non-homologous end joining-mediated DSB repair.

96 Micro-homology-mediated non-homologous end joining (MMEJ) can also be used but t

97 Non homologous end joining (NHEJ) is an important proces

98 The non homologous end-joining (NHEJ) pathway of double-stra

99 Non homologous end-joining (NHEJ)-mediated repair of DNA

100 Prkdc(sc/sc) mutant mice have a defect in non-homologous end joining (NHEJ) and are sensitive to I

101 There is increased DNA mis-repair by non-homologous end joining (NHEJ) and both NHEJ and homo

102 DNA non-homologous end joining (NHEJ) and homologous recombi

103 re reported for translesion synthesis (TLS), non-homologous end joining (NHEJ) and homologous recombi

104 promotes the two major DSB repair pathways, non-homologous end joining (NHEJ) and homologous recombi

105 ebrafish (Danio rerio) and livestock through non-homologous end joining (NHEJ) and homology-directed

106 rotein plays a crucial role in DNA repair by non-homologous end joining (NHEJ) and interacts with the

107 trand break repair that buttresses canonical non-homologous end joining (NHEJ) and is manifest in NHE

108 Non-homologous end joining (NHEJ) and single-strand anne

109 Homology-directed repair and non-homologous end joining (NHEJ) are the two major DSB

110 d into end-to-end chromosome fusions via the non-homologous end joining (NHEJ) double-strand break re

111 Mammalian cells require non-homologous end joining (NHEJ) for the efficient repa

112 The repair of DSBs by non-homologous end joining (NHEJ) has been extensively s

113 ohomology-mediated end joining (MMEJ), while non-homologous end joining (NHEJ) has not been reported.

114 Initiation of HR in the G1 phase blocks non-homologous end joining (NHEJ) impairing DSB repair.

115 DNA double-strand break (DSB) repair by non-homologous end joining (NHEJ) in human cells is init

116 d by either homologous recombination (HR) or non-homologous end joining (NHEJ) in mammalian cells.

117 Non-homologous end joining (NHEJ) involves limited proce

118 Non-homologous end joining (NHEJ) is a key cellular proc

119 Non-homologous end joining (NHEJ) is a major DNA double-

120 Non-homologous end joining (NHEJ) is a major pathway to

121 Non-homologous end joining (NHEJ) is critical for the ma

122 DNA by nucleotide excision repair (NER) and non-homologous end joining (NHEJ) is essential for maint

123 DNA double strand break (DSB) repair by non-homologous end joining (NHEJ) is initiated by DSB de

124 Non-homologous end joining (NHEJ) is the main repair pat

125 Non-homologous end joining (NHEJ) is the major model pro

126 m the RAG post-cleavage complex (PCC) to the non-homologous end joining (NHEJ) machinery to promote a

127 are non-recurrent and can be generated by a non-homologous end joining (NHEJ) mechanism.

128 capabilities; however, the preponderance of non-homologous end joining (NHEJ) mediated repair events

129 ificantly reduced in ku70Delta and lig4Delta non-homologous end joining (NHEJ) mutant backgrounds com

130 The available evidence indicates a role for non-homologous end joining (NHEJ) of DNA double-strand b

131 ial components of the complex that catalyzes non-homologous end joining (NHEJ) of DNA double-strand b

132 E4 34k and E1b 55k proteins of DSB repair by non-homologous end joining (NHEJ) on extrachromosomal su

133 We hypothesize that inhibiting non-homologous end joining (NHEJ) or enhancing homology-

134 regulated process performed predominantly by non-homologous end joining (NHEJ) or homologous recombin

135 and breaks (DSBs) are repaired by either the non-homologous end joining (NHEJ) or homologous recombin

136 uble strand breaks (DSBs) can be repaired by non-homologous end joining (NHEJ) or homology-directed r

137 peated DNA stability involves suppression of non-homologous end joining (NHEJ) or other recombination

138 implicates breaks followed by repair through non-homologous end joining (NHEJ) or stalled fork repair

139 se IIIalpha is a component of an alternative non-homologous end joining (NHEJ) pathway for DNA double

140 The non-homologous end joining (NHEJ) pathway is used in div

141 are generally thought primarily to utilize a non-homologous end joining (NHEJ) pathway to repair DSBs

142 referentially repaired using the error-prone non-homologous end joining (NHEJ) pathway.

143 R) while stymieing repair by the error-prone non-homologous end joining (NHEJ) pathway.

144 epair of double strand breaks (DSBs) via the non-homologous end joining (NHEJ) pathway.

145 f microhomology in both alt-EJ and classical non-homologous end joining (NHEJ) remains unclear.

146 Inhibition of Non-Homologous End Joining (NHEJ) repair either pharmaco

147 B-mediated homologous recombination (HR) and non-homologous end joining (NHEJ) repair systems, leadin

148 ught to arise from a moderate attenuation of non-homologous end joining (NHEJ) repair, the role of DE

149 Non-homologous end joining (NHEJ) repairs DNA double str

150 knockout MEFs exhibited distinct defects in non-homologous end joining (NHEJ) when compared to their

151 Here, we suggest a role of LKB1 in non-homologous end joining (NHEJ), a major DNA double-st

152 nit (DNA-PKcs) plays a key role in mediating non-homologous end joining (NHEJ), a major repair pathwa

153 Non-allelic homologous recombination (NAHR), non-homologous end joining (NHEJ), and microhomology-med

154 otes, DNA DSBs are predominantly repaired by non-homologous end joining (NHEJ), but DNA ends can also

155 for sequence-specific gene knockout through non-homologous end joining (NHEJ), but it remains ineffi

156 ir factors, in particular those required for non-homologous end joining (NHEJ), do not form discrete

157 non-allelic homologous recombination (NAHR), non-homologous end joining (NHEJ), fork stalling and tem

158 hen can become the substrate for error-prone non-homologous end joining (NHEJ), generating mutations

159 xcision repair (NER), mismatch repair (MMR), non-homologous end joining (NHEJ), homologous recombinat

160 absolutely indispensable for its function in non-homologous end joining (NHEJ), little is known about

161 Yeast Rap1 protects telomeres from non-homologous end joining (NHEJ), plays important roles

162 common DSB repair mechanism in human cells, non-homologous end joining (NHEJ), rejoins broken DNA en

163 In contrast to non-homologous end joining (NHEJ), TMEJ efficiently repa

164 air by homologous recombination (HR) but not non-homologous end joining (NHEJ), using HeLa cell lines

165 Mutant hamster cells (xrs-5), deficient in non-homologous end joining (NHEJ), were irradiated at 37

166 s of either homologous recombination (HR) or non-homologous end joining (NHEJ), whereas SUMO2/3 was r

167 bition induces a repair defect that involves non-homologous end joining (NHEJ).

168 repair from homologous recombination (HR) to non-homologous end joining (NHEJ).

169 itical for their proper joining by classical non-homologous end joining (NHEJ).

170 role in double-strand break (DSB) repair by non-homologous end joining (NHEJ).

171 for DSB repair: homologous recombination and non-homologous end joining (NHEJ).

172 karyotic cells are predominantly repaired by non-homologous end joining (NHEJ).

173 CC4 (LX) complex, which functions during DNA non-homologous end joining (NHEJ).

174 y involving homologous recombination (HR) or non-homologous end joining (NHEJ).

175 inase, accumulate 53BP1 and are processed by non-homologous end joining (NHEJ).

176 pair DSBs: homologous recombination (HR) and non-homologous end joining (NHEJ).

177 ) through either homologous recombination or non-homologous end joining (NHEJ).

178 K for survival at collapsed forks, likely in non-homologous end joining (NHEJ).

179 ily repaired by homologous recombination and non-homologous end joining (NHEJ).

180 f two pathways, homologous recombination and non-homologous end joining (NHEJ).

181 that support single-strand break repair and non-homologous end joining (NHEJ).

182 ch between homologous recombination (HR) and non-homologous end joining (NHEJ).

183 A repair: homology directed repair (HDR) and non-homologous end joining (NHEJ).

184 nt, while still protecting telomeres against non-homologous end joining (NHEJ).

185 DSBs), thereby influencing the efficiency of non-homologous end joining (NHEJ).

186 . patens mutants for DSB factors involved in non-homologous end joining (NHEJ).

187 s, homology-directed recombination (HDR) and non-homologous end joining (NHEJ).

188 switch recombination (CSR), are repaired by non-homologous end joining (NHEJ).

189 Non-homologous end-joining (NHEJ) and homologous recombi

190 Non-homologous end-joining (NHEJ) and homologous recombi

191 s) are repaired by two principal mechanisms: non-homologous end-joining (NHEJ) and homologous recombi

192 e repair of DNA double-strand breaks (DSBs): non-homologous end-joining (NHEJ) and homologous recombi

193 elomeres and DNA-PKcs, a protein involved in non-homologous end-joining (NHEJ) and immune responses,

194 The bacterial non-homologous end-joining (NHEJ) apparatus is a two-com

195 ase II (TOP2) are rejoined by TDP2-dependent non-homologous end-joining (NHEJ) but whether this promo

196 TRADD facilitates non-homologous end-joining (NHEJ) by recruiting NHEJ rep

197 tional error-prone pathway of DSB repair via non-homologous end-joining (NHEJ) catalysed by Ku and DN

198 to be associated with the components of the non-homologous end-joining (NHEJ) complex and participat

199 rate that combined inactivation of the XRCC4 non-homologous end-joining (NHEJ) DNA repair gene and p5

200 Allele-specific gene disruption induced by non-homologous end-joining (NHEJ) DNA repair offers a po

201 tebrate immune system rely on factors in the non-homologous end-joining (NHEJ) DNA repair pathway to

202 nce of the vector accompanied by an apparent non-homologous end-joining (NHEJ) event at the other.

203 As the non-homologous end-joining (NHEJ) factor, Ku70/80 (Ku),

204 cells where homologous recombination (HR) or non-homologous end-joining (NHEJ) had been suppressed by

205 Non-homologous end-joining (NHEJ) is a critical error-pr

206 chanisms for DSB repair; in mammalian cells, non-homologous end-joining (NHEJ) is a major DSB repair

207 Non-homologous end-joining (NHEJ) is the most prominent

208 The alternative non-homologous end-joining (NHEJ) machinery facilitates

209 Ku70-Ku80 heterodimers promote the non-homologous end-joining (NHEJ) of DNA breaks and, as

210 ge response pathways, and promotes efficient non-homologous end-joining (NHEJ) of dysfunctional telom

211 DSBs are repaired by either error prone non-homologous end-joining (NHEJ) or error-free homologo

212 the X family that has been implicated in the non-homologous end-joining (NHEJ) pathway during repair

213 A-PKcs subunits, is the key component of the non-homologous end-joining (NHEJ) pathway of DNA double

214 y (CHO) cell lines that are defective in the non-homologous end-joining (NHEJ) pathway of DNA double-

215 The non-homologous end-joining (NHEJ) pathway repairs DNA do

216 DNA fragments, which are not repaired by the non-homologous end-joining (NHEJ) pathway.

217 strand breaks (DSBs) can be repaired by the non-homologous end-joining (NHEJ) pathway.

218 depleting HP1 from cells did not affect the non-homologous end-joining (NHEJ) pathway: instead it el

219 ed via the single-strand annealing (SSA) and non-homologous end-joining (NHEJ) pathways in a manner d

220 ent from translocation breakpoint junctions, non-homologous end-joining (NHEJ) pathways of DNA repair

221 osomes and generate genome rearrangements by non-homologous end-joining (NHEJ) processes in specializ

222 dation of a novel assay to measure mutagenic non-homologous end-joining (NHEJ) repair in living cells

223 In contrast, alleles created by non-homologous end-joining (NHEJ) repair of double-stran

224 and 80-kDa subunits that participate in the non-homologous end-joining (NHEJ) repair pathway for rej

225 NA breaks are processed and repaired via the non-homologous end-joining (NHEJ) repair pathway.

226 homology directed repair (HDR) and decreased non-homologous end-joining (NHEJ) repair, suggesting tha

227 efficiency, which are typically repaired by non-homologous end-joining (NHEJ) resulting in nonspecif

228 A prokaryotic non-homologous end-joining (NHEJ) system for the repair

229 age on the repair of double-strand breaks by non-homologous end-joining (NHEJ) was determined using c

230 a DNA nuclease that plays important roles in non-homologous end-joining (NHEJ), a major double-strand

231 Here we report a novel role of non-homologous end-joining (NHEJ), a pathway of double-s

232 Non-homologous end-joining (NHEJ), a repair process pred

233 n (HR) repair with a concomitant decrease in non-homologous end-joining (NHEJ), accounting for the im

234 Metnase promotes non-homologous end-joining (NHEJ), and knockdown causes

235 syl-DNA phosphodiesterase 2 (TDP2)-dependent non-homologous end-joining (NHEJ), but whether this proc

236 lant DNA-repair machinery predominantly uses non-homologous end-joining (NHEJ), making the homologous

237 DNA-PKcs; encoded by PRKDC) functions in DNA non-homologous end-joining (NHEJ), the major DNA double

238 Since mammalian cells can repair DSBs by non-homologous end-joining (NHEJ), we hypothesized that

239 Finally, we extend this non-homologous end-joining (NHEJ)-based technique by dir

240 ever, mutagenic events caused by error-prone non-homologous end-joining (NHEJ)-mediated repair are in

241 NA damage being channelled through repair by non-homologous end-joining (NHEJ).

242 repaired predominantly in mammalian cells by non-homologous end-joining (NHEJ).

243 trand break (DSB) repair pathways, including non-homologous end-joining (NHEJ).

244 tic opening before their repair by classical non-homologous end-joining (NHEJ).

245 DNA double-strand breaks (DSBs) repaired by non-homologous end-joining (NHEJ).

246 echanisms, homologous-recombination (HR) and non-homologous-end-joining (NHEJ).

247 breakpoint junctions revealed signatures of non-homologous end-joining, non-allelic homologous recom

248 te-specific recombination mediated by Cre or non-homologous end joining of DNA double-strand breaks i

249 repair (HR), while counteracting error-prone non-homologous end joining of DNA double-strand breaks.

250 e excision repair and with its known role in non-homologous end joining of double strand breaks, perh

251 poration, and it efficiently participates in non-homologous end joining of double-strand DNA breaks.

252 7 or its adapters impairs Ku80 removal after non-homologous end joining of DSBs.

253 ther demonstrate that the excursions promote non-homologous end joining of dysfunctional telomeres an

254 derived hiPSCs where successful deletion and non-homologous end joining of up to 725 kb reframed the

255 d cellular DNA repair proteins that catalyze non-homologous end-joining of DNA double-strand breaks.

256 or ATR signalling is required for efficient non-homologous end-joining of dysfunctional telomeres.

257 This may include non-homologous end-joining of strand breaks resulting fr

258 SceI-induced break can be repaired either by non-homologous end joining or by recombination between t

259 A double-strand breaks can be eliminated via non-homologous end joining or homologous recombination.

260 DSBs are repaired by non-homologous end-joining or homology directed repair (

261 tid means that repair of DSBs occurs through non-homologous end-joining or microhomology-mediated end

262 s in a G1-like DNA repair mode which favours non-homologous end joining over interchromosomal recombi

263 The non-homologous end joining pathway uses pre-existing pro

264 double-strand DNA break (DSB) repair via the non-homologous end joining pathway, as unrepaired DSBs a

265 DNA-PKcs, which is integral to the non-homologous end joining pathway, thus negatively regu

266 an be further improved by suppression of the non-homologous end joining pathway.

267 uble strand breaks, initiating repair by the non-homologous end joining pathway.

268 B) repair as the underlying mechanism of the non-homologous end joining pathway.

269 s expressing BCR-ABL1 utilize an alternative non-homologous end-joining pathway (ALT NHEJ) to repair

270 e catalytic subunit (DNA-PKcs) regulates the non-homologous end-joining pathway of DNA double-strand

271 leotides during gap-filling synthesis in the non-homologous end-joining pathway of double-strand brea

272 In the non-homologous end-joining pathway, DNA ends are brought

273 As a member of the non-homologous end-joining pathway, it is also involved

274 ch as those encountered by pol lambda in the non-homologous end-joining pathway, may have been solved

275 in the proximity of the break were due to a non-homologous end-joining pathway, while larger deletio

276 in repairing DNA double-strand breaks by the non-homologous end-joining pathway.

277 telomeres to protect them from engaging the non-homologous end-joining pathway.

278 h recombination use overlapping but distinct non-homologous end joining pathways to repair DNA double

279 This overexpression triggers SSB repair and non-homologous end-joining pathways to increase DNA repa

280 involved defective base excision repair and non-homologous end-joining, pathways required for repair

281 n of subtelomeric duplications and find that non-homologous end-joining predominates.

282 The ykoV gene product, a homolog of the non-homologous end-joining protein Ku, is shown to assoc

283 itro analyses suggest that in the absence of non-homologous end joining proteins, L1 elements may uti

284 Coding ends are ligated by non-homologous end-joining proteins to form a functional

285 the processing of dysfunctional telomeres by non-homologous end joining, putatively through stabiliza

286 DSB repair pathway independent of rad-51 and non-homologous end joining, raising the possibility that

287 r shown to have homologous recombination and non-homologous end joining related activities and also t

288 led to enhanced phosphorylation of DNA-PK, a non-homologous end joining repair protein, in Hec-108 ce

289 Wnt signalling enhances non-homologous end-joining repair in CRC, which is media

290 Although DNA non-homologous end-joining repairs most DNA double-stran

291 Repair of chromosome breaks by non-homologous end joining requires the XRCC4-ligase IV

292 at take part in homologous recombination and non-homologous end joining, respectively, were transcrip

293 A DSB repair by homologous recombination and non-homologous end joining, respectively.

294 t provides DNA ligase activity for classical non-homologous end joining (the predominant DNA double-s

295 igase IV.XRCC4 complex (LX) functions in DNA non-homologous-end joining, the main pathway for double-

296 e heterodimer Ku70/Ku80, has a major role in non-homologous end joining-the main pathway in mammals u

297 implicated in both base excision repair and non-homologous end joining through in vitro studies.

298 a novel component regulating the switch from non-homologous end-joining to homologous recombination.

299 double-strand break repair switches from DNA non-homologous end-joining to homologous recombination.

300 removal of histone H3 from the genome during non-homologous end joining was promoted by both ATM and