ライフサイエンスコーパス: non-neoplastic

1 Dystrophin is expressed in the non-neoplastic and benign counterparts of GIST, RMS and

2 ricular signs and symptoms are the result of non-neoplastic and neoplastic space-occupying lesions.

3 We found that the average elastic moduli of non-neoplastic and tumor-bearing optic nerves were appro

4 m cell-associated Sox2 but nevertheless were non-neoplastic as they coexpressed Rb and/or retained tw

5 a higher level in glioblastoma cells than in non-neoplastic astrocytes.

6 reased in malignant astrocytomas, but not in non-neoplastic astrocytes.

7 essing CLL B cells that do not use VH1-69 or non-neoplastic B cells that express VH1-69.

8 ling of wild-type cultured mouse astrocytes, non-neoplastic B8 astrocytes, B8 astrocytoma cultures, a

9 We conclude that acid exposure in non-neoplastic BAR-T cells causes early antiproliferativ

10 e effects on proliferation in neoplastic and non-neoplastic BAR-T cells.

11 the G(1)-S cell cycle checkpoint, we exposed non-neoplastic Barrett's cells to acidic media (pH 4.0)

12 In non-neoplastic Barrett's epithelial (BAR-T) cells, in co

13 sed significantly in CCA cells compared with non-neoplastic biliary epithelial cells.

14 atic and 8 extrahepatic CCs in comparison to non-neoplastic biliary tissue specimens, using methyl-Cp

15 invading human glioblastoma cells present in non-neoplastic brain parenchyma secrete high levels of T

16 osome profiling of human proneural tumor and non-neoplastic brain tissue with computational deconvolu

17 y increased in human glioma as compared with non-neoplastic brain tissue.

18 ion was elevated in GBM tumors compared with non-neoplastic brain tissues, portended a worse prognosi

19 in a subset of human GBMs compared with the non-neoplastic brain.

20 y is elevated in glioblastomas compared with non-neoplastic brain.

21 ly KLF5 mRNA was expressed at high levels in non-neoplastic breast epithelial cells and in normal hum

22 se of balance can generally be attributed to non-neoplastic causes, such as otitis media, otosclerosi

23 sis using T51B rat liver epithelial cells, a non-neoplastic cell line previously developed for carcin

24 ymbiotic relationship between neoplastic and non-neoplastic cell types dictate where and when cancers

25 -causing genetic changes, contributions from non-neoplastic cells and signals in the tumor microenvir

26 The majority of the non-neoplastic cells are tumor-associated macrophages (T

27 fixation methods to separate neoplastic from non-neoplastic cells in primary colorectal cancers and m

28 e to killing by methotrexate (MTX) than were non-neoplastic cells in the same culture.

29 origin, deregulated intracellular signaling, non-neoplastic cells in the tumor microenvironment and g

30 revealed critical roles for the NF1 gene in non-neoplastic cells in the tumor microenvironment, the

31 the preferential killing of neoplastic over non-neoplastic cells of the same derivation.

32 Conversely, the glia were distinct from the non-neoplastic cells that strongly expressed the stem ce

33 ated that calpain 3 moves from the nuclei of non-neoplastic cells to the cytoplasm of malignant cells

34 Neither neoplastic nor non-neoplastic cells were killed once they had stopped m

35 st of cone-like neoplastic cells and diverse non-neoplastic cells whose roles in tumorigenesis have n

36 nt research has revealed a critical role for non-neoplastic cells within the tumor microenvironment i

37 , which constitute a large proportion of the non-neoplastic cells within the tumor microenvironment,

38 unoreactivity was detected in neoplastic and non-neoplastic cells, including in intestinal metaplasti

39 re complex tumors composed of neoplastic and non-neoplastic cells, which each individually contribute

40 e exacerbated by Nf1 heterozygosity in other non-neoplastic cells.

41 ty of solid tumor lines but had no effect on non-neoplastic cells.

42 come neoplastic as well as heterozygosity in non-neoplastic cells.

43 erg (H/RS) cells in a reactive background of non-neoplastic cells.

44 cancer cells and smMLCK highly expressed in non-neoplastic cells.

45 ty in both the pre-neoplastic/neoplastic and non-neoplastic cellular compartments contribute to gliom

46 ls in papillomas were elevated over those in non-neoplastic choroid plexus.

47 f cytoskeletal associated tyrosine kinase in non-neoplastic, circulating, hematopoietic cells.

48 We found that HCC and adjacent non-neoplastic cirrhotic tissue have considerable overla

49 perinsulinism of infancy display a dramatic, non-neoplastic clonal expansion of beta cells that have

50 arcinomas, respectively, but not in adjacent non-neoplastic colon biopsy samples from the same patien

51 al copies is present in cancer cells than in non-neoplastic colon cells, and sequence microheterogene

52 g for differentiation between neoplastic and non-neoplastic colonic lesions.

53 e risk of developing a second malignancy and non-neoplastic complications, most notably cardiac disea

54 amples and age/gender/smoking-status-matched non-neoplastic controls from the Lung Cancer in Central

55 provides trophic support to the tumor cells' non-neoplastic counterparts.

56 fluids of 18 patients with benign tumors or non-neoplastic cysts.

57 ns in serum that distinguish neoplastic from non-neoplastic disease within the ovary.

58 cancer who had undergone cholecystectomy for non-neoplastic disease.

59 estigation in both other tumour types and in non-neoplastic disease.

60 d risks of cytotoxic therapy when treating a non-neoplastic disease.

61 eneficially directed toward the treatment of non-neoplastic diseases in which autoimmune mechanisms w

62 fore, MPE concept and paradigm can extend to non-neoplastic diseases including diabetes mellitus, car

63 eriampullary neoplasms, and 51 patients with non-neoplastic diseases who underwent pancreatic resecti

64 ncommon and sometimes fatal, neoplastic, and non-neoplastic diseases.

65 several cancers and is also associated with non-neoplastic diseases; although the underlying mechani

66 east cancer tissues whereas not expressed in non-neoplastic ducts.

67 BV-PTLD and subclassifying as neoplastic and non-neoplastic EBV-PTLD were 0.73 (95% CI: 0.54-0.93) an

68 lse negatives) and two biopsied lesions were non-neoplastic entities on pathological review (false po

69 the superficial cells of preneoplastic over non-neoplastic epithelia (P<0.0001), consistent with a r

70 l of expression in normal hepatocytes and in non-neoplastic epithelial cells.

71 Vascular malformations are non-neoplastic expansions of blood vessels that arise du

72 sion: Estrogens stimulate IL-6 production in non-neoplastic female BECs and in neoplastic BECs expres

73 MKN1 gastric cancer and HFE-145 immortalized non-neoplastic gastric mucosa cell lines.

74 tatic lymph nodes (22 cases), microdissected non-neoplastic gastric mucosa of EBVaGC (five cases), an

75 inal-type gastric cancer compared to matched non-neoplastic gastric samples (P = 0.018).

76 n gastric cancer samples compared to matched non-neoplastic gastric samples (P = 0.019).

77 ssion in gastric tumors and in corresponding non-neoplastic gastric samples.

78 1.5-fold in 35% of tumors compared to paired non-neoplastic gastric tissue.

79 in 22 pairs of gastric tumors and in matched non-neoplastic gastric tissue.

80 17 pairs of gastric tumors and corresponding non-neoplastic gastric tissue.

81 tric tumors from CEA/Tag mice, compared with non-neoplastic gastric tissue.

82 ith those of HCC (n = 40), and a spectrum of non-neoplastic hepatic lesions including normal liver an

83 ent is well established, its contribution in non-neoplastic hepatic pathologies has not been investig

84 ISG) in PH5CH8 cells, which are derived from non-neoplastic hepatocytes transformed with large T anti

85 (ATAC-seq) was performed in MFD-1, OE33, and non-neoplastic HET1A cells.

86 multicentric Castleman disease patients and non-neoplastic HHV8-associated syndromes.

87 in LNCaP, 22Rv1 and LAPC4 cells, but not in non-neoplastic human prostate epithelial PWR-1E cells.

88 300 RNA-Seq libraries covering 30 different non-neoplastic human tissues and cells as well as 15 mou

89 receptor agonist, isoproterenol, result in a non-neoplastic hypertrophy and hyperplasia of the rat pa

90 ly, crosstalk between neoplastic B cells and non-neoplastic immune and stromal cells in the microenvi

91 ue classifications of cancerous, healthy and non-neoplastic inflamed tissue samples with an accuracy

92 in-like plasmin fragments are generated in a non-neoplastic inflammatory setting.

93 re variably detected in leukocyte DNA and/or non-neoplastic intestinal mucosa of these patients.

94 we found no evidence for mosaicism in APC in non-neoplastic intestinal mucosa.

95 98 of these polyps were adenomas and 80 were non-neoplastic lesions (of which 62 were hyperplastic).

96 ital vascular malformations are tumour-like, non-neoplastic lesions caused by disorders of vascular t

97 SOC) and 100 control patients with benign or non-neoplastic lesions.

98 scade were determined in tumor and adjacent, non-neoplastic liver specimens by Western blot analysis

99 ion of Hippo pathway components in tumor and non-neoplastic liver tissue from 7 pediatric patients wi

100 Overall, surrounding non-neoplastic liver tissue was highly positive for GADD

101 antly decreased when compared to surrounding non-neoplastic liver tissue.

102 onstrated that HCC scored lower than matched non-neoplastic liver tissues consistently and significan

103 ants; the median contribution of B6 cells to non-neoplastic liver was 50%.

104 The overall contribution of each strain to non-neoplastic liver was determined using the PCR assay

105 ed intense cytoplasmic expression of MEG3 in non-neoplastic liver with absent or very weak expression

106 ssion in tumorigenic tissue versus adjacent, non-neoplastic liver.

107 an be objectively distinguished from HCC and non-neoplastic liver.

108 In contrast, most cells in non-neoplastic lung tissue appear not to express the gen

109 mited expression in both adenocarcinomas and non-neoplastic lungs.

110 nomas/dysplasias, and corresponding adjacent non-neoplastic mucosa.

111 ting Src phosphorylation, compared with HT22 non-neoplastic nerve cells.

112 edgehog, and Notch, which play a key role in non-neoplastic neural stem cells.

113 s that characterize these tumors relative to non-neoplastic optic nerve tissue.

114 , in murine optic gliomas relative to normal non-neoplastic optic nerve.

115 , but a 13% decrease per year for all proven non-neoplastic or unresected polyps (p<0.0001).

116 5% of ovarian tumor samples as compared with non-neoplastic ovarian tissue samples.

117 ul as markers that can distinguish MCNs from non-neoplastic pancreatic cystic lesions.

118 emonstrated that SPARC mRNA was expressed in non-neoplastic pancreatic ductal epithelial cells, but w

119 s had higher levels of nuclear TRAIL-R2 than non-neoplastic pancreatic tissue, which correlated with

120 levels of TRAIL-R2 in sections of PDACs and non-neoplastic peritumoral ducts from patients.

121 samples and resection of all (neoplastic and non-neoplastic) polyps.

122 lines of NIH 3T3 cells had the properties of non-neoplastic, preneoplastic, and neoplastic cells, res

123 activity nor showed any cytotoxicity against non-neoplastic prostate epithelial PWR-1E cells.

124 iling of laser capture microdissected normal non-neoplastic prostate epithelial tissue and compared i

125 er levels of IL-6 than their counterparts in non-neoplastic prostate.

126 Interestingly, expression of Aurora-A in non-neoplastic prostates correlated with seminal vesicle

127 man prostate cancers, but is a rare event in non-neoplastic prostatic epithelium suggesting a role fo

128 Clinically, they are often misdiagnosed as non-neoplastic pseudocysts leading to failed opportuniti

129 r probability of survival than patients with non-neoplastic PTLD and non-cases.

130 Association analysis in panels of CC-RCC and non-neoplastic samples using the RFLPs generated by each

131 gths in 18,430 samples, including tumors and non-neoplastic samples, across 31 cancer types.

132 n was significantly higher in tumors than in non-neoplastic samples.

133 s and prostate tumors when compared with the non-neoplastic samples.

134 ether angiostatin is generated in mice under non-neoplastic settings.

135 tein expression in gastric cancer and paired non-neoplastic specimens from 33 patients and also in ga

136 was markedly lower in tumors than in paired non-neoplastic specimens.

137 changes, including those associated with the non-neoplastic state in the B8 transgenic mouse, those a

138 Hypoxia promotes the expansion of non-neoplastic stem and precursor cell populations in th

139 I-N87) and primary human gastric tissues (31 non-neoplastic stomach (NS) and 25 gastric carcinomas (G

140 verging data have revealed the importance of non-neoplastic stromal cells in influencing tumor growth

141 hether epigenetic modifications occur in the non-neoplastic stromal cells.

142 ween epithelial cancer cells and surrounding non-neoplastic stromal cells.

143 F-kappaB) pathway to apoptotic resistance in non-neoplastic, telomerase-immortalized esophageal squam

144 ed 21 cases of thyroid tumours, six cases of non-neoplastic thyroid pathology, 30 population controls

145 intestinal cancer, and sarcoma from adjacent non-neoplastic tissue in mouse models.

146 adenoid cystic carcinoma (ACC), relative to non-neoplastic tissue of origin.

147 core antigen (WHcAg) and WHxAg expression in non-neoplastic tissue.

148 short half-life, so it is rarely detected in non-neoplastic tissue.

149 liver and stomach as compared to background non-neoplastic tissue.

150 a low level of mutated DNA was identified in non-neoplastic tissue.

151 aGC cases, 8 of 10 metastatic carcinomas, 14 non-neoplastic tissues from 27 EBVaGC cases, and 12 of 2

152 We collected colorectal tumor and non-neoplastic tissues from 31 patients with IBD and col

153 nces were more common in both neoplastic and non-neoplastic tissues from different geographic areas t

154 for rapid distinction between cancerous and non-neoplastic tissues is an important goal in disease d

155 In non-neoplastic tissues, reactivity was highly selective

156 tion were observed in neoplastic vs adjacent non-neoplastic tissues, suggesting that targeted MSP amp

157 kidney, and lung carcinomas and in adjacent non-neoplastic tissues, using immunohistochemistry.

158 Within neurofibromas, PR was expressed by non-neoplastic tumor-associated cells and not by neoplas

159 ical stages of UC-associated carcinogenesis (non-neoplastic UC colon, dysplasia, and carcinoma).

160 In contrast, no non-neoplastic UC mucosa showed HPP1 methylation.

161 r II mRNA were up-regulated significantly in non-neoplastic WAP-CRD-BP mammary tissue.