ライフサイエンスコーパス: non-overlapping

1 nches of homotypic and heterotypic pairs are non-overlapping.

2 these enzymes are thought to be functionally non-overlapping.

3 widespread distributions, which are largely non-overlapping.

4 thetic peptide fragments, instead of the 155 non-overlapping 15-mer peptides theoretically necessary

5 A non-overlapping 18 bp sequence carries a transcriptional

6 g the same data partitioned into a series of non-overlapping 2 Mb windows reveals a strong, non-linea

7 over four months resulted in a significant, non-overlapping 40%-50% reduction in the number of senil

8 nce review, with several participants having non-overlapping 95% credible intervals, both groups did

9 ' of rarity and threat are therefore largely non-overlapping across groups, as are areas chosen to ma

10 r results suggest that SF1 contains multiple non-overlapping activities that block diverse transcript

11 of functional networks that are anatomically non-overlapping and are associated with specific behavio

12 rded alternatively as closely related and as non-overlapping and incompatible.

13 Thus, the two strains have non-overlapping and modular amyloid cores that determine

14 gulated by AFF1-SEC and AFF4-SEC are largely non-overlapping and perform distinct functions.

15 propose that FANCI and FANCD2 have partially non-overlapping and possibly even opposing roles during

16 ith each reference, we also store all of its non-overlapping and statistically significant alignments

17 the LEM and DNA binding sites on BAF(2) are non-overlapping and that both subunits of the BAF(2) dim

18 ce is opposite, indicating that SMURF2 has a non-overlapping and, in some respects, opposite function

19 at most of the seasonally suitable areas are non-overlapping, and China may have been a peripheral pa

20 Legionella species were found to be largely non-overlapping, and only seven core effectors were shar

21 function accomplished independently with two non-overlapping antisense morpholino oligonucleotides re

22 mino acids (aa) 1-760 by testing a series of non-overlapping APC segments.

23 uman cells comprises alternating and largely non-overlapping approximately 10-15 Mb domains marked by

24 were principally useful in discerning three non-overlapping areas of consensus genetic deletion.

25 verging thalamic pathways that terminated in non-overlapping barrel center and septal compartments in

26 gonists nor by endogenous ligands indicating non-overlapping binding with the canonical pocket.

27 apping enzymatic activities can have unique, non-overlapping biological functions in the cell.

28 indirect and null), implying three distinct, non-overlapping bipolar cell to ganglion cell circuits.

29 Two non-overlapping but functionally related gene expression

30 on and trans-synaptic tracing identified two non-overlapping candidate tongue motor cortical areas.

31 CVN contains two non-overlapping carbohydrate-binding sites that bind the

32 to isolate the BRCA2 gene, we have cloned 73 non overlapping cDNAs from a set of nine YACs spanning 6

33 ent neuropeptides are expressed in specific, non-overlapping cells in the brain in all three species.

34 on DNA substrates but appear to have largely non-overlapping cellular functions, ranging from Okazaki

35 to H(2)O(2) for 1 h also elicited these two non-overlapping cellular responses in both dopaminergic

36 Because it targets multiple non-overlapping cellular targets, ExoT performs several

37 thods is limited by the number of spectrally non-overlapping chromophores.

38 ally significant differences as indicated by non-overlapping CIs.

39 integrate multiple data sources and discover non-overlapping, class-specific RNA binding patterns of

40 d surface IB4 labeling to purify three major non-overlapping classes of neurons: 1) IB4(+)SNS-Cre/TdT

41 tosomal dominant disorders with distinct and non-overlapping clinical features.

42 ng algorithm to find an optimal selection of non-overlapping cliques, resulting in a very fast algori

43 novel bi-clustering algorithm for generating non-overlapping clusters of reporter genes and condition

44 y the generation of multiple indicators with non-overlapping color spectra.

45 cal properties for an extensive selection of non-overlapping colors.

46 easuring the statistical significance of any non-overlapping combination of TFBS in a window.

47 explicit function, identifies the number of non-overlapping compartments, assigns membership to comp

48 tamorphic segments, however, CapI-hes1 has a non-overlapping complementary expression pattern to that

49 on period of the overlapping compared to the non-overlapping condition after participants knew the se

50 A non-overlapping condition contained two sequences that d

51 nterior ectosylvian gyrus were scattered and non-overlapping, consistent with the non-tonotopic organ

52 ween clones or the physical distance between non-overlapping contigs.

53 ic tiling, which allows for the complete but non-overlapping coverage of the dendritic fields, is est

54 mulation and characterization of packings of non-overlapping cubic particles.

55 The majority of the non-overlapping cvt mutants were found to be at least pa

56 5.0, 4.6 and 5.0 for our data combined with non-overlapping data from the literature, for IDDM4 on c

57 Four non-overlapping deletion regions were observed: (1) at 6

58 Apparently partial and non-overlapping deletions of the 5' or 3' end of a candi

59 Three non-overlapping deletions spanning 144 amino acids just

60 (MAP)2-positive dendrites, they appeared in non-overlapping dendritic compartments.

61 ng TADs using Hi-C data assume that TADs are non-overlapping, despite evidence for a nested structure

62 These define at least two non-overlapping determinants on human p53 that are in di

63 The two separate non-overlapping DNA binding domains in the ERCC1-XPF het

64 proteins interact in vitro and in cells via non-overlapping domains and provide evidence consistent

65 pression patterns have diverged to delineate non-overlapping domains in most organ systems including

66 It is believed that chromosomes occupy non-overlapping domains in the interphase nucleus, and t

67 ifferent promoters that direct expression in non-overlapping domains in the larval imaginal discs.

68 nitiation of tooth development, in distinct, non-overlapping domains in the mesenchyme and the epithe

69 lysine and arginine residues located in two non-overlapping domains mediate GAG interactions, and th

70 , Olig2 and Nkx2.2 are expressed in adjacent non-overlapping domains of ventral neuroepithelium.

71 ck loops that result in the establishment of non-overlapping domains of Wnt1 and Fgf8 on either side

72 data indicate that HDAC3 comprises separate, non-overlapping domains that contribute to the unique pr

73 smic astrocytes are organized into spatially non-overlapping domains that encompass both neurons and

74 Asymmetric isoform expression occurs in non-overlapping domains, with pitx2c in left dorsal dien

75 linking have been mapped to at least three, non-overlapping domains.

76 ate binding and that they are located in two non-overlapping domains.

77 response to different inputs, with only the non-overlapping dynamics efficiently activating target g

78 red for normal haematopoiesis with distinct, non-overlapping effects from ASXL1 and acts as a haploin

79 bivalent biparatopic antibody targeting two non-overlapping epitopes on HER2 can induce HER2 recepto

80 de linker two antibody fragments recognizing non-overlapping epitopes on the same antigen.

81 gel separation, an array of antibodies with non-overlapping epitopes, and mass spectrometry.

82 g VHHs were identified recognizing distinct, non-overlapping epitopes.

83 w demonstrate that these two genes also have non-overlapping essential functions in testis developmen

84 d and perceived more readily than temporally non-overlapping events [4-11], essentially enhancing the

85 became less similar than representations of non-overlapping events.

86 The non-overlapping expression of dbx and eve, or dbx and hb

87 The non-overlapping expression of different neuropeptides ma

88 onstrated that these two MTMs exhibit mostly non-overlapping expression patterns and that MTM-green f

89 enes specify distinct cell types and exhibit non-overlapping expression patterns during Arabidopsis d

90 0 genes identified four genes with primarily non-overlapping expression patterns in the dorsal horn.

91 ve identified three Wnt genes with specific, non-overlapping expression patterns in the metanephric k

92 ity by showing that FIL and YAB3 control the non-overlapping expression patterns of FRUITFULL (FUL) a

93 nd the functional implication of the largely non-overlapping expression patterns of tubulin genes are

94 19c) indicates that these genes have largely non-overlapping expression patterns suggesting that thes

95 Despite these non-overlapping expression patterns, Cripto; Cryptic dou

96 l geniculate nucleus (LGN) segregate to form non-overlapping eye-specific domains.

97 tum dots and upconverting nanoparticles with non-overlapping fluorescent emissions, the proposed meth

98 initiate its further 5'-->3' processing into non-overlapping fragments.

99 ate algorithm SLCP(2) is derived to identify non-overlapping functional modules.

100 afferents are ascribed different and largely non-overlapping functional roles (for example texture or

101 The mechanisms explaining their divergent, non-overlapping functions are unclear.

102 h show distinct expression patterns and have non-overlapping functions during mesendoderm and asymmet

103 inflammation these data thus identify novel non-overlapping functions for ERK1 and ERK2 that are bio

104 min A deficiency, thus demonstrating largely non-overlapping functions for these enzymes in retinoid

105 cells, and ontogenically distinct MSCs have non-overlapping functions in endochondrogenesis and HSC

106 n plant tissues, suggesting non-redundant or non-overlapping functions in plants.

107 and AS analysis, we demonstrate distinct and non-overlapping functions of these chromatin modifiers o

108 ndicates that ASC and these NLRs also elicit non-overlapping functions, but the molecular basis for t

109 different laminin isoforms exhibit specific, non-overlapping functions.

110 lls and, although structurally similar, have non-overlapping functions.

111 This crevice is adjacent to the non-overlapping ganglioside-binding site of BoNT/B.

112 In the case of T4, a deletion of a non-overlapping gene pair pseT.2 and pseT.3 identified a

113 The presence of a non-overlapping gene set has persisted with successive d

114 s provided as individual reports specific to non-overlapping, gene-model-centric genomic loci.

115 viscous homogeneous populations, namely that non-overlapping generations hinder the evolution of altr

116 le effects on the dynamics of a species with non-overlapping generations, with one effect not detecta

117 ary transition between overlapping genes and non-overlapping genes and demonstrates the high rates of

118 We identity non-overlapping genes required for T3SS1- and T3SS2-medi

119 date, have homologs in more microbes than do non-overlapping genes, and are therefore likely more con

120 he characteristic phenotype in patients with non-overlapping genetic lesions.

121 endrites to stereotypical, intercalating but non-overlapping glomeruli.

122 rkedly by allele frequency when divided into non-overlapping groups by allele frequency range.

123 ly important for establishing or maintaining non-overlapping groups of GlcNAc-1-P- and Man-6-P-modifi

124 N amplifications (37%) identify three almost non-overlapping groups of high-stage neuroblastoma, each

125 ed clustering associated transcripts into 22 non-overlapping groups, the functional analysis of which

126 controls could be clearly separated into two non-overlapping groups.

127 SINs are further subdivided into two non-overlapping groups: those producing acetylcholine (c

128 ith the best traditional coding measure, the non-overlapping hexamer frequency count, and find that t

129 other, could be attributed to two different, non-overlapping HSA21 regions.

130 mmune response was to a combination of three non-overlapping HTT Exon1 coded peptides, conjugated to

131 ence, however, had identified two different, non-overlapping human erythroid ankyrin subdomains, Zu5

132 solic CLOCK and PER2 displayed a significant non-overlapping IF staining pattern.

133 These mutations are non-overlapping in distribution with RAS mutations and a

134 y, these results were replicated in a second non-overlapping independent dataset of U.S. Marines (N=9

135 iscovery of natural killer cell subsets with non-overlapping inhibitory receptors for parental class

136 rsal striatum, these two subpopulations show non-overlapping innervation of distinct terminal fields

137 means of a data-driven statistical model of non-overlapping intensity correlations.

138 mplex, SUMO functions as a bridge by forming non-overlapping interfaces with UBC9 and PIAS1.

139 ssociation data, partition associations into non-overlapping LD clusters, map variants to genes and p

140 that lin-35 Rb and cki-1 Cip/Kip contribute non-overlapping levels of G1/S inhibition in C. elegans.

141 the distribution of mGluR5 and Oxtr revealed non-overlapping localization of these receptors within t

142 Here, we report an unexpected finding of non-overlapping localization of these two proteins in mo

143 somal dominant LFSNHL linked to adjacent but non-overlapping loci on 4p16, DFNA6 and DFNA14.

144 the CSF-1R, they are expressed in a largely non-overlapping manner by mature neurons.

145 vation in either a temporally overlapping or non-overlapping manner during their transient response t

146 been shown to be expressed in a distinct and non-overlapping manner in the five left upper quadrant (

147 tein docking show that Adx and CPR bind in a non-overlapping manner to the same helical domain in P45

148 hes based on successively assigning the best non-overlapping match (Best Match Cascade, BMC).

149 Non-overlapping mazes did not share any hallways with an

150 n of the overlapping mazes compared with the non-overlapping mazes in regions typically associated wi

151 les in AD, causing neurotoxicity by distinct non-overlapping mechanisms affecting neuronal function a

152 d and spontaneous release by independent and non-overlapping mechanisms.

153 ure neural similarity across overlapping and non-overlapping memories during immediate and 1-week ret

154 1) the zeta-eta region contains at least two non-overlapping methylation signals; (2) different fragm

155 atic autoimmune lesions, recognized distinct non-overlapping MHC-class-II-restricted peptides derived

156 anisms may condense into a major complex and non-overlapping minor complexes; the concepts that speci

157 Non-overlapping N- and C-terminal regions of ETR-3 conta

158 ntibodies were raised in rabbits against two non-overlapping N-terminal NOTCH3 sequences.

159 ate (an activator of Notch) are expressed in non-overlapping narrow stripes.

160 ch larger than the length difference between non-overlapping neighboring gene pairs.

161 how in vivo and in vitro that members of two non-overlapping neocortical IN populations, expressing s

162 in either PV+ or SOM+ neurons have distinct, non-overlapping neurological features: mice lacking MeCP

163 enes are expressed in closely associated but non-overlapping neurons within the hypothalamus, and MCH

164 n CCR5 gene led to identification of largely non-overlapping off-target sites, raising the possibilit

165 e describe that this method can be used with non-overlapping oligonucleotides.

166 ontains long terminal repeats (LTR) and four non-overlapping open reading frames (ORF), presumably or

167 ositive-stranded RNA genome that encodes two non-overlapping open reading frames separated by a short

168 ole species, males and females occupy mostly non-overlapping parts of morphological space; the overal

169 gesting that they evolved by independent and non-overlapping pathways from their unrelated AdoMet fam

170 Burkholderia, which were detected in largely non-overlapping patient subsets.

171 nd opa is activated by abdA but the adjacent non-overlapping patterns are not due to mutual opa-pnt r

172 lphavbeta6 and alphavbeta8 were expressed in non-overlapping patterns by keratinocytes (KCs) and main

173 hese molecules are expressed in adjacent but non-overlapping patterns in the epithelium covering cres

174 nolocalisation studies revealed distinct and non-overlapping patterns of distribution for ShAR1alpha

175 ing specificities and by their substantially non-overlapping patterns of expression in the soybean pl

176 51.7%, yet transcript distribution revealed non-overlapping patterns of expression in tissues and cu

177 a) and Wg (a Wnt), are produced, in adjacent non-overlapping patterns, under Hox control in mesoderm

178 pecific, and occurs in many different, often non-overlapping patterns.

179 within the alpha domain was identified using non-overlapping PauA peptides to block the interaction b

180 Two antisera raised to unique, non-overlapping peptide sequences located within the ext

181 Individual non-overlapping peptides of PadA or bovine microplasmino

182 mouse was generated and revealed significant non-overlapping phenotypes with the TGF-beta2 null mouse

183 the phenotype after Atr deletion, supporting non-overlapping physiological roles for these related DN

184 e permease has been expressed in contiguous, non-overlapping polypeptide fragments containing the N-t

185 Tregs are identified as two non-overlapping populations in the T-zone and follicular

186 We first identify two non-overlapping populations of layer 2 pyramidal neurons

187 neous and evoked glutamate release activates non-overlapping populations of NMDA receptors.

188 The findings indicate that non-overlapping populations of striatal projection neuro

189 ion) was often higher in overlapping than in non-overlapping portions of cougar home ranges.

190 g assignments, and producing a single set of non-overlapping predicted domains.

191 landscapes in 42 primary ependymomas in two non-overlapping primary ependymoma cohorts, with the goa

192 Expression of Cripto and Cryptic is non-overlapping prior to gastrulation, since Cripto is e

193 Moreover, we find that two non-overlapping protein fragments, one consisting of HRN

194 serum albumin precursor (67 kDa) from eight non-overlapping proteolytic fragments, and the identity

195 iously associated with rearrangements of the non-overlapping proximal 16p11.2 600 kb BP4-BP5 interval

196 We identified 29 non-overlapping randomised controlled trials with three

197 While historically considered non-overlapping, recent evidence has uncovered crosstalk

198 same class use tiling to form complete, yet non-overlapping, receptive fields.

199 quired the UBQLN UBA domain, was mediated by non-overlapping regions of TDP-43, and was abrogated by

200 s comprising a moving plaid are presented to non-overlapping regions of the (monocular) receptive fie

201 ependent Drosophila RNAi lines targeting two non-overlapping regions of the CG5155 transcript, we dem

202 d using recombinant fusion proteins encoding non-overlapping regions of the IgPKD domains.

203 t the 30 kDa CPSF and PABII proteins bind to non-overlapping regions of the NS1A protein effector dom

204 tor interactions are modular and mediated by non-overlapping regions of the receptor transmembrane an

205 We define two non-overlapping regions, Bnr1p-L1 (1-466) and Bnr1p-L2 (

206 Two non-overlapping regions, Delta12 (amino acids 896-1219)

207 mapping of these LOH regions revealed three non-overlapping regions, one of which was refined to a 0

208 to be more enriched with small RNA loci than non-overlapping regions.

209 Both proteins bind to central, albeit non-overlapping, regions of MDM2 and suppress MDM2 activ

210 ion of Treg cells into distinct subsets with non-overlapping regulatory activities.

211 Most of these patterns are driven by non-overlapping regulatory elements, including ones for

212 In addition to cells with non-overlapping replication rounds, we observed cells in

213 icity representations including regions with non-overlapping representations of visual space.

214 ces or events are transformed into discrete, non-overlapping representations.

215 p-front therapeutic combinations that target non-overlapping resistance a preferred approach.

216 Such non-overlapping response patterns are not observed even

217 ved competition among neurons with spatially non-overlapping RFs, measured by negative spike timing c

218 ublished, each of which highlights a single, non-overlapping risk locus.

219 screen yielded only approximately 1% of all non-overlapping RNAs along with 75% of previously annota

220 ctors which suggests that TA isoforms have a non-overlapping role for plant metabolism.

221 channels, allowing each to play a unique and non-overlapping role in Ca2+ signaling.

222 related Cks gene, Cks85A, plays a distinct, non-overlapping role in Drosophila, and the two genes ca

223 orage-independent growth, suggesting key and non-overlapping roles for these genes in the control of

224 hese two signaling systems have distinct and non-overlapping roles in ES/ED development.

225 ranscriptional regulators Six1 and Six2 play non-overlapping roles in nephron progenitors.

226 emonstrate that FGFR1 and FGFR3 have largely non-overlapping roles in regulating invasion/metastasis

227 e in placental development, but play largely non-overlapping roles in the development of many embryon

228 teins possess multiple paralogs that perform non-overlapping roles in vivo.

229 Rotterdam Study and sought replication in a non-overlapping sample of 719 individuals.

230 de the folding and time-dependent packing of non-overlapping secondary structure elements in the prot

231 The number of non-overlapping seeds a mapper selects determines the se

232 so that each route contained overlapping and non-overlapping segments), we were able to test whether

233 phosphorylation state of the downstream and non-overlapping sequences.

234 t Set1A and Set1B each localize to a largely non-overlapping set of euchromatic nuclear speckles, sug

235 o regulates motor axon pathfinding through a non-overlapping set of functional domains.

236 ile ser-4 is expressed in an almost entirely non-overlapping set of sensory and interneurons.

237 osylase (ADPRT) activity toward distinct and non-overlapping set of targets.

238 apping, this strategy yields study-specific, non-overlapping sets of all identified metabolites.

239 Interestingly, despite selecting largely non-overlapping sets of features, the two filters did fi

240 nt variation reveal polymorphisms in largely non-overlapping sets of genes associated with variation

241 Sequences and 3D structures contain non-overlapping sets of information that both determine

242 suggest that Hsp70 and Hsp90 have partially non-overlapping sets of obligate protein clients in canc

243 specific Rh5 and Rh6 opsins are expressed in non-overlapping sets of R8 cells, in a precise pairwise

244 atively performed quantitative RT-PCR with 3 non-overlapping short amplicons for 14 target RNAs in FF

245 ossibility of long-chain RNA analysis with 3 non-overlapping short amplicons in standardized-preserve

246 d simultaneously by antibodies that target a non-overlapping site to additively increase parasite inh

247 petition studies, peptides were grouped into non-overlapping Sites 1, 2, or 3.

248 owing cells, and they phosphorylated largely non-overlapping sites on shared substrates.

249 rfaces of the Runt domain occur at distinct, non-overlapping sites within the domain.

250 th scFvs with the toxin, which correspond to non-overlapping sites.

251 ation was in contrast to earlier findings of non-overlapping SOM + and CR + interneuron populations i

252 wo cFHF-2 transcript isoforms are present in non-overlapping spatial distributions in the neural tube

253 some components have been linked to a set of non-overlapping spliceosomopathy phenotypes in humans, a

254 nput patterns established that: (1) multiple non-overlapping stable trajectories can be embedded in t

255 es of transition between the overlapping and non-overlapping states in the two species and found that

256 d medial nucleus accumbens innervate largely non-overlapping striatal targets, with the latter also s

257 Taken together, the best fitting non-overlapping structures would constitute a 'mosaic' b

258 t splits alignments with many sequences into non-overlapping sub-alignments prior to estimating amino

259 strocyte hypertrophy were evaluated in seven non-overlapping subfields in the mid-cortex including th

260 ak down the given network into a sequence of non-overlapping subnetworks such that reachability can b

261 2 and Cbln4 are broadly expressed in largely non-overlapping subpopulations of excitatory cortical ne

262 overhangs partitions the cDNA fragments into non-overlapping subpopulations.

263 seem to be assembled from multiple smaller, non-overlapping subregions of other neurons in the same

264 pathogen populations will self-organize into non-overlapping subsets of antigenic variants if cross-p

265 ), Sdk2, Dscam, and DscamL--are expressed by non-overlapping subsets of chick retinal neurons and pro

266 which are commonly described as transcribing non-overlapping subsets of genes.

267 ostatin, and calretinin were demonstrated in non-overlapping subsets of interneurons.

268 expression of BRL1 and BRL3 is restricted to non-overlapping subsets of vascular cells.

269 of this system, in which multiple SBPs with non-overlapping substrate specificities compete for the

270 r finding the most statistically significant non-overlapping subtrees of a hierarchical clustering of

271 two carbonylation stages are sequential and non-overlapping, such that epoxide carbonylation goes to

272 phenotype in three triple mutants harboring non-overlapping T-DNA insertions in cytokinin AHK recept

273 However, the overlapping and non-overlapping target transcripts involved in this proc

274 sease dynamics: early AD is characterised by non-overlapping temporal atrophy and temporo-parietal hy

275 ogical ontologies to report a minimal set of non-overlapping terms.

276 asses partition the body wall into distinct, non-overlapping territorial domains and thus are organiz

277 astrocytes is the "tiling" of the brain with non-overlapping territories.

278 osomes appear to be organized into discrete, non-overlapping "territories".

279 ion response are expressed at different, and non-overlapping, times of day.

280 r of ARE mRNA stability, displayed a largely non-overlapping tissue distribution with AUF1 and was pr

281 mise of enhanced leukaemia cell killing with non-overlapping toxicities.

282 py in patients with advanced NSCLC and has a non-overlapping toxicity profile with chemotherapy.

283 This approach works well for simple, non-overlapping transcription pathways.

284 channel beta-subunit is complex, comprising non-overlapping transcription units that give rise to at

285 , 2010), e.g. networks composed of lines and non-overlapping triangles.

286 g triplets and of a stratified sample of the non-overlapping triplets revealed accuracies of 93% and

287 We find that even a small number of non-overlapping Tudor domains or a substantial reduction

288 l sulcus coded location identity even across non-overlapping views, whereas the right presubiculum co

289 by comparing the number of sequence reads in non-overlapping windows between patient and control samp

290 re calculated in each GC content class using non-overlapping windows of 50kb.

291 the (relative) frequency distribution using non-overlapping windows of length 3.

292 nce through the regulation of genes that are non-overlapping with pathogen-induced genes.

293 lated with disease duration were lateral and non-overlapping with striatal regions showing reduced D2

294 ive chromatin in a pattern that is generally non-overlapping with that of Polycomb, a repressor of Ho

295 pO2-sensitive Cys residues were largely non-overlapping with those identified previously as hype

296 e biological functions that are distinct and non-overlapping with those of the more prevalent ceramid

297 ulators needed for cell survival in vivo are non-overlapping with those required in vitro.

298 recording the frequency distribution of the non-overlapping words of length 3 in each of the reading

299 First, three non-overlapping zones of the MLd receive inputs from thr