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1 s FFA2-selective, whereas propionate (C3) is non-selective.
2 E) that converted the pore from chloride- to non-selective.
3 inhibitors that are either iNOS-selective or non-selective.
5 have the behavioral toxicity associated with non-selective 5-HT2 receptor agonists, targeting the 5-H
6 c footprint, but the peripheral spread stays non-selective-a surprising finding given a number of ana
7 sorption, while an ultra-thin metal film has non-selective absorption in the near infrared wavelength
8 d with drug-eluting stents may be due to the non-selective actions of antimitogenic drugs on endothel
11 s 8-(p-sulfophenyl)-theophylline) (8-SPT), a non-selective adenosine receptor antagonist which has be
12 ird and 8-sulphophenyltheophylline (8-SPT; a non-selective adenosine receptor antagonist) before the
13 (5.0 micromol/kg, i.p.), a centrally active, non-selective adenosine receptor antagonist, attenuated
16 S-21680 (1.0-10.0 micromol/kg, i.p.) and the non-selective agonist, N(6)-ethylcarboximidoadenosine (N
17 sion and neuronal function in vertebrates by non-selective agonistic actions on 5-HT(1) and 5-HT(2) r
20 adrenoceptor antagonist) and phentolamine (a non-selective alpha-adrenoceptor antagonist) were determ
21 himbine (alpha(2)-antagonist), phentolamine (non-selective alpha-antagonist) and bretylium tosylate (
23 licits feeding, (2) prior treatment with the non-selective AMPA/KAR antagonist, CNQX, suppresses ATPA
24 Further, LH pretreatment with either the non-selective AMPAR/KAR antagonist, 6-cyano-7-nitroquino
26 or many transcription factors are relatively non-selective and found at high frequency within the gen
28 (OPG) GEM model, we report novel defects in non-selective and selective attention without an accompa
31 and more consistently produced than with the non-selective antagonist gabazine, and both were blocked
32 (PET) dopamine subtype 2/3 receptor (D2/3R) non-selective antagonist tracers suggests that obese (OB
33 r dimer population, but the receptor subtype non-selective antagonists atropine and N-methylscopolami
37 Depletion of this essential nutrient induces non-selective autophagy by inhibiting TORC1, leading to
40 ee Cl- currents, Xenopus RPE cells exhibit a non-selective background current (Ibkg) which has a line
42 zepine receptor partial agonist MRK-696, and non-selective benzodiazepine receptor full agonists, mid
43 ng compounds were compared with those of the non-selective benzodiazepine receptor partial agonist MR
44 ay promote mild bronchodilation that offsets non-selective beta blockade-induced bronchoconstriction
45 Recent experience indicates that combined non-selective beta- and alpha-blockade with carvedilol i
47 s of the beta-adrenergic agents propranolol (non-selective beta-antagonist) and salbutamol (beta(2)-a
48 ts in lesser clinical benefits than combined non-selective beta-blockade with carvedilol at the maxim
50 e variability of physicians' preferences for non-selective beta-blockers (BBs) and endoscopic varicea
51 ysine (NTA) and deactivating agents to block non-selective binding between GO-NTA sheets and non-targ
52 tantly, the selective substrates can be made non-selective by insertion of a proline kink at P(3), wi
53 Polycystin-2 (PC2), the PKD2 protein, is a non-selective Ca(2+)-permeable cation channel which may
54 In addition, we show that GLR genes encode non-selective Ca(2+)-permeable channels that can regulat
59 of extracellular pH (pHo) on calcium-sensing non-selective cation (csNSC) channels in cultured mouse
60 187 (1 microM), to activate Ca(2+)-activated non-selective cation (NSC) channels (T84 cells) and larg
63 al vanilloid 1 (TRPV1) is a Ca(2+) permeable non-selective cation channel activated by physical and c
64 rophysiological recordings show that it is a non-selective cation channel and that its activity depen
65 These effects could be prevented with the non-selective cation channel blocker Gadolinium (Gd(3+))
68 describe the properties of a Ca2+-permeable non-selective cation channel current that is activated i
70 lt taste receptor is a constitutively active non-selective cation channel derived from the VR-1 gene.
71 ential channel vanilloid type 1 (TRPV1) is a non-selective cation channel expressed in sensory neuron
74 bed a constitutively active, Ca2+-permeable, non-selective cation channel in freshly dispersed rabbit
75 ribed a constitutively active Ca2+-permeable non-selective cation channel in freshly dispersed rabbit
77 al canonical 5 (TRPC5), a calcium-permeable, non-selective cation channel is expressed in the periphe
78 sensitive multistate channels resembling the non-selective cation channel of sea urchin and mouse spe
81 4,5-bisphosphate (PtdIns(4,5)P2) -modulated, non-selective cation channel that belongs to the family
82 Transient receptor potential 7 (TRPC7) is a non-selective cation channel that can be activated by bo
83 stin-2 (PC2) is a TRP-type, Ca(2+)-permeable non-selective cation channel that plays an important rol
84 potential vanilloid 1 (TRPv1) receptor is a non-selective cation channel that serves as a marker of
86 Localization and function of the polymodal non-selective cation channel TRPV1 (transient receptor p
87 ctance and then activates a Na(+)-permeable, non-selective cation channel via depolarization-induced
88 opening of a cyclic nucleotide-gated (CNG), non-selective cation channel which depolarizes the cells
89 ted that WT ML1 is a multiple subconductance non-selective cation channel whose function is inhibited
90 tery myocytes ET-1 evokes a Ca(2+)-permeable non-selective cation channel with properties similar to
91 that R282E-PepT1 behaved as a peptide-gated non-selective cation channel with the ion selectivity se
92 2l1 or Pkdl), encoding polycystin-L (PCL), a non-selective cation channel, increases neuronal excitab
94 rat insulinoma cell death by activation of a non-selective cation channel, which leads to irreversibl
102 as Ca(2+)-activated Cl() channels (CaCC) and non-selective cation channels (NSCC) have been suggested
104 act with and regulate members of a family of non-selective cation channels (TRPC) which have been sug
106 tively, and E(r) values indicated that these non-selective cation channels are highly permeable to Ca
107 ents, and families - which included putative non-selective cation channels for the NaCl treatment and
108 linoma cells and suggest that this family of non-selective cation channels has a widespread distribut
109 RPC4 proteins function as Ca(2+) conducting, non-selective cation channels in endothelial, smooth mus
110 transient receptor potential (TRP) family of non-selective cation channels in murine megakaryocytes f
111 tion-activated cyclic nucleotide-gated (HCN) non-selective cation channels in neurons carry currents
112 f the transient receptor potential family of non-selective cation channels is a polymodal nociceptor.
113 egarding Cl(-) channels in the ER/SR and the non-selective cation channels or putative 'Ca(2+) leak c
114 regarding Cl- channels in the ER/SR and the non-selective cation channels or putative 'Ca2+ leak cha
116 ogical and pharmacological properties of the non-selective cation channels stimulated by the physiolo
118 (TRP channel (TRPC) 1-7 are Ca(2+)-permeant, non-selective cation channels that are widely expressed
119 d-aspartate (NMDA) receptors are heteromeric non-selective cation channels that require the binding o
120 ntial (TRP) superfamily comprises a group of non-selective cation channels that sense and respond to
121 (TRPM7) channels are novel Ca(2+)-permeable non-selective cation channels ubiquitously expressed.
128 extracellular Ca(2+); (ii) large conductance non-selective cation channels; and (iii) Ca(2+)-dependen
129 ing a constitutively active Ca(2+)-permeable non-selective cation conductance (I(cat)) in rabbit ear
130 cid, an antagonist for the calcium-activated non-selective cation conductance (ICAN ) abolished the e
132 (GSK), a TRPV4 channel agonist, activated a non-selective cation conductance that coupled to activat
133 to a Ca(2+)-inhibited, voltage-independent, non-selective cation conductance that has similar proper
134 This is accompanied by up-regulation of a non-selective cation conductance with TRPM4-like propert
135 mic acid, a blocker of the calcium-activated non-selective cation conductance, abolished the effect o
138 s the cell by recruiting a calcium-activated non-selective cation current (ICAN) capable of generatin
139 rtal vein myocytes noradrenaline activates a non-selective cation current (Icat) which involves a tra
140 , as well as a mechanically-sensitive inward non-selective cation current characteristic of Piezo2.
141 of cells expressing TRPC1+STIM1 activated a non-selective cation current, I(SOC), that was blocked b
142 -acetyl-sn-glycerol (OAG) stimulated similar non-selective cation currents and Ca2+ entry in HSY cell
143 ading to the postulation that post-traumatic non-selective cation currents are determined by TRPM4/SU
144 cells, arginine-vasopressin (AVP) activated non-selective cation currents associated with TRPC6 acti
146 These currents are produced by relatively non-selective, cation-permeable channels or pores in the
147 ezo proteins as subunits of Ca(2+)-permeable non-selective cationic channels for detection of noxious
148 ponsible for flow-sensitive non-inactivating non-selective cationic channels which depolarize the mem
150 n decrease unitary conductance and produce a non-selective channel while the presence of a positive c
151 nt MPV17 to reveal that this protein forms a non-selective channel with a pore diameter of 1.8 nm and
154 state duplication frequencies measured under non-selective conditions (10(-4) to 10(-5) ) confirmed t
156 of genomic sequences targeted by T-DNA under non-selective conditions were similar to those of random
158 restin itself possesses a stretch-sensitive, non-selective conductance that is largest in the presenc
159 tracellular chloride is a stretch-sensitive, non-selective conductance within the lateral membrane, G
163 eatment of APP-overexpressing cells with the non-selective COX inhibitor ibuprofen (1 microM, 48 h) o
164 ol), a non-specific NO synthase inhibitor, a non-selective COX inhibitor or combined inhibition durin
165 roup subset received 100 mg of indomethacin (non-selective COX-1 and COX-2 inhibitor), and another HS
167 Here, we described an outward rectifying non-selective current mediated by a TRP ion channel in i
168 lia also revealed TRPM4-like, Ca2+-activated non-selective currents (I CAN) with an EC50 of 1.2 micro
169 G-monomethyl-l-arginine (l-NMMA, 10 mm), the non-selective cyclooxygenase inhibitor ketorolac trometh
170 clooxygenase-2 inhibitor) or indomethacin (a non-selective cyclooxygenase inhibitor) had significant
176 e during sessions with good avoidance but is non-selective during poor avoidance, with high release c
184 subtypes in the memory-impairing effects of non-selective GABAAR PAMs has not been fully elucidated.
185 are primarily involved in the impairment, by non-selective GABAAR PAMs, of visual recognition and vis
188 howing efficacy of sarcosine, an endogenous, non-selective glycine-reuptake inhibitor mediated by Gly
191 (intrathecal) injection of carbenoxolone (a non-selective hemichannel blocker) and selective connexi
192 er sos1 mutants more tolerant to paraquat, a non-selective herbicide causing oxidative stress, indica
193 ustained bradycardia induced by S1P receptor non-selective immunosuppressive agonists in wild-type mi
194 ugh the E1224A mutant has full activity in a non-selective in vitro transcription assay, it is temper
195 two hypotheses: that stress would lead to a non-selective increase in the expression of Pavlovian bi
196 cker, improves the clinical outcome, whereas non-selective inhibition of both forms of tumour necrosi
197 e of PDE7A1 catalytic domain in complex with non-selective inhibitor 3-isobutyl-1-methylxanthine and
198 portion of posterior telencephalon receives non-selective, interspersed inputs from all glomeruli, w
200 nt receptor potential ankyrin 1 (TRPA1) is a non-selective ion channel, which is expressed in nocicep
201 ular, monovalent cation transporters such as non-selective ion channels and cation:proton antiporters
202 hannels defines a new family of functionally non-selective ion channels, and also provides important
205 BA(A) receptor agonist) or kynurenic acid (a non-selective ionotropic glutamate receptor antagonist)
214 sphingosine 1-phosphate (S1P) receptors in a non-selective manner decreases disease activity in patie
215 The samples were enumerated on selective and non-selective media and on doxycycline (4 microg/ml) med
217 cterisation of a novel group of functionally non-selective members of the prokaryotic 'inward rectifi
220 tamate receptor mGluR5) and 10 mum LY341495 (non-selective mGluR blocker), but not by 80 mum AP5 (NMD
221 epths, implying that reconstructions using a non-selective mixture of morphotypes could potentially b
224 Indatraline is an antidepressive agent and a non-selective monoamine transporter inhibitor that block
232 Because deficiency of sodium leak channel, non-selective (Nalcn) causes lethal apnea in humans and
233 ssense mutations in the sodium leak channel, non-selective (NALCN) in four families affected by CLIFA
234 l lobe and type II neuroblasts compared with non-selective neuroblasts, neurons and glia revealed a r
236 cotinic antagonist methyllycaconitine or the non-selective nicotinic antagonist mecamylamine indicate
237 after intra-peritoneal administration of the non-selective nitric oxide synthase (NOS) inhibitor, N(G
238 tension as does systemic administration of a non-selective nitric oxide synthase (NOS) inhibitor.
240 ad any of three clinically important errors: non-selective non-steroidal anti-inflammatory drugs (NSA
241 Cyclo-oxygenase-2 selective inhibitors and non-selective non-steroidal anti-inflammatory drugs (NSA
242 uld reduce ulcer complications compared with non-selective non-steroidal anti-inflammatory drugs, but
243 nitro-l-arginine methyl ester hydrochloride (non-selective NOS inhibitor); (3) 5 mm N-propyl-l-argini
245 ved following the systemic administration of non-selective NOS inhibitors, and thus provides support
246 CVC at eNOS-inhibited (41 +/- 3%CVCmax) and non-selective NOS-inhibited (40 +/- 4%CVCmax) sites were
248 cantly less likely to have been prescribed a non-selective NSAID if they had a history of peptic ulce
249 2 inhibitors and aspirin than in those using non-selective NSAIDs and aspirin; significantly fewer un
250 sion that COX-2 inhibitors are preferable to non-selective NSAIDs in patients with chronic pain and c
251 exposure to cyclo-oxygenase 2 selective and non-selective NSAIDs was compared with remote exposure t
255 with different selective drugs in respect to non-selective ones, most of them are only able to delay
258 The purpose of this study was to assess a non-selective opioid receptor agonist, biphalin, in decr
260 ile, intrathecal pretreatment with naloxone, non-selective opioid receptor antagonist, did not affect
262 xpressed human rod opsin, driven by either a non-selective or ON-bipolar cell-specific promoter, can
265 Our data suggest that claudin-16 forms a non-selective paracellular cation channel, rather than a
266 n effect replicated pharmacologically with a non-selective PDE4 inhibitor, implicating cAMP signaling
268 4 evolved by recruitment and adaptation of a non-selective phosphodiesterase and a matrix component i
272 tide inhibitor of calcineurin (CaN-AIP); the non-selective PP1/PP2A inhibitors okadaic acid (0.5, 10,
274 smolytes, proposedly due to the opening of a non-selective protein channel of unknown molecular ident
276 duced inhibition of EPSCs was reduced by the non-selective protein kinase inhibitors H-7 (100 microM)
277 ical analyses imply that CsgG is an ungated, non-selective protein secretion channel that is expected
278 nal poly(IC) exposure and treatment with the non-selective purinergic antagonist suramin to test the
281 ockade of CRH receptors in the mPFC with the non-selective receptor antagonist d-Phe-CRH (50 ng or 10
283 Inhibition of lymphocyte recirculation by non-selective S1P receptor agonists produces clinical im
286 ght a slight shift in prescribing toward the non-selective serotonin reuptake inhibitor bupropion hyd
287 ory, unintended declines in case finding and non-selective serotonin reuptake inhibitor substitute tr
289 single divalent metal-binding site which is non-selective, since Mn2+, Co2+ and Zn2+ compete with Mg
292 entire catalytic pocket of MT1-MMP, whereas non-selective substrates are kinked at the conserved P(3
295 s of the NaK channel from Bacillus cereus, a non-selective tetrameric cation channel, in its Na+- and
298 in DRG neurones, which was attenuated by the non-selective TRP channel antagonist ruthenium red (10 m
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