ライフサイエンスコーパス: nonallergic

1 re positive (allergic) and 29 were negative (nonallergic).

2 d hay fever, suggesting that pathways may be nonallergic.

3 less frequently non-IgE-mediated allergy or nonallergic.

4 sponses at 24 h were similar in both groups (nonallergic, 110 +/- 24 eosinophils/mm2; allergic, 113 +

5 for asthma among adolescents, especially for nonallergic adolescents and those exposed to maternal sm

6 d IL-4 synthesis both in T cells from normal nonallergic adult subjects as well as in naive T cells f

7 f this resistance is preserved in nonatopic, nonallergic adults and is unmasked during exposure to an

8 of resistance to HDM challenge in nonatopic, nonallergic adults was muted T-cell activation in the pe

9 n of irritants may facilitate development of nonallergic AHR.

10 The role of the Nlrp3 inflammasome in nonallergic airway hyperresponsiveness (AHR) has not pre

11 sophagitis, with a more pronounced effect in nonallergic and younger individuals, especially in the p

12 in RV strain 1B-infected naive BALB/c mice (nonallergic) and identified CCL7 and IFN regulatory fact

13 is classified into allergic asthma (AA) and nonallergic asthma (NA), yet both are treated identicall

14 Increased risks were observed for nonallergic asthma (OR 1.80; 95% CI 1.27-2.55) and rhini

15 : eosinophilic allergic asthma, eosinophilic nonallergic asthma and noneosinophilic nonallergic asthm

16 t gain (GWG), with incidence of allergic and nonallergic asthma in offspring.

17 Allergic and nonallergic asthma severity in children can be affected

18 Our goal was to understand the mechanism of nonallergic asthma that leads to airway hyperreactivity

19 er, the association of maternal obesity with nonallergic asthma was observed in boys (2.39, 1.40-4.09

20 When we evaluated allergic versus nonallergic asthma, neopterin levels tended to be associ

21 hilic nonallergic asthma and noneosinophilic nonallergic asthma.

22 eopterin levels tended to be associated with nonallergic asthma.

23 in AA Treg compared with healthy control and nonallergic asthmatic counterparts.

24 e major bee venom allergen PLA isolated from nonallergic beekeepers show increased expression of IL-1

25 No eosinophil infiltrate was observed in nonallergic biopsies at 30 min and 6 h, whereas signific

26 py, as well as their increased expression in nonallergic but high-dose allergen-exposed beekeepers.

27 8) from 52 highly characterized allergic and nonallergic children (0.5-17 years) with severe treatmen

28 ase had more epilepsy in their lifetime than nonallergic children (logistic regression, adjusted odds

29 olerant (P < .001) and non-peanut-sensitized nonallergic children (P < .001).

30 ower neonatal T-cell PKCzeta expression than nonallergic children (P < 0.001).

31 he effect of being overweight was greater in nonallergic children (RR = 1.77, 95% CI: 1.26, 2.49) tha

32 ased risk of new-onset asthma in boys and in nonallergic children.

33 4 levels and POIT but not from nonsensitized nonallergic children.

34 of age had lower cord blood BAFF levels than nonallergic children.

35 alence among allergic children but not among nonallergic children.

36 nce of published systematic reviews (SRs) on nonallergic comorbidities of atopic eczema (AE).

37 Seasonality of clinical diagnoses of nonallergic conjunctivitis among the 4143 patients (2364

38 n to compare demographics and seasonality of nonallergic conjunctivitis with allergic conjunctivitis.

39 Weekly total clinical diagnoses at UCSF of nonallergic conjunctivitis, allergic conjunctivitis, gla

40 different in allergic subjects from that in nonallergic control subjects (deltaPD20 = -0.40 versus -

41 Thirteen nonallergic control subjects were also assessed.

42 38 AR sufferers and eight nonallergic controls were exposed to grass pollen for 3

43 in serum were similar to levels measured in nonallergic controls, but HDM-specific levels of IgA2 in

44 cells from nickel-allergic patients, but not nonallergic controls, show significant IL-9 production i

45 L-5, and IL-13) content relative to those in nonallergic controls.

46 er psychosocial outcomes compared with their nonallergic counterparts; however, few studies have pros

47 itis up to 16 years of age, particularly for nonallergic disease.

48 an important cytokine in the pathogenesis of nonallergic diseases, especially in diseases that includ

49 s obtained from allergic patients (n=11) and nonallergic donors (n=5).

50 ed higher proliferation to grass pollen than nonallergic donors (P = 0.002, and 0.010, respectively),

51 ression in blood DCs of patients and healthy nonallergic donors by qPCR.

52 OD1-primed dendritic cells from allergic and nonallergic donors were characterized in vitro on their

53 rmal CCL22 and IL-10 secretion compared with nonallergic donors.

54 in an indirect assay by using basophils from nonallergic donors.

55 rstood, but likely include both allergic and nonallergic elements.

56 been limited by a poor understanding of how nonallergic environmental exposures, such as air polluti

57 nflammation in response to both allergic and nonallergic exposures and suggest that airway inflammato

58 s might regulate asthma, particularly in its nonallergic forms, such as asthma associated with air po

59 nary stent implantation were compared with a nonallergic group (n=250) matched for demographics and a

60 osinophil degranulation in both allergic and nonallergic groups.

61 pheral blood and nasal biopsy specimens from nonallergic healthy control subjects (n = 3) and patient

62 ute anaphylaxis with several control groups (nonallergic, history of allergen-triggered anaphylaxis,

63 mmatory conditions, such as the psoriasis, a nonallergic hyperproliferative skin inflammatory disorde

64 Ag exposure through induction of a modified, nonallergic immune response.

65 DHRs may be allergic or nonallergic in nature, with drug allergies being immunol

66 hil levels, with a more pronounced effect in nonallergic individuals (65.9 +/- 25.3 vs 1.4 +/- 1.1 eo

67 cates that allergen-specific CD4+ T cells in nonallergic individuals are distinct from those in aller

68 e addition of alpha-gal-specific IgG Ab from nonallergic individuals changed the IgE recognition of B

69 the pathological pathways are controlled in nonallergic individuals remains unclear.

70 (PBMC) culture from CM allergic patients and nonallergic individuals were assessed.

71 cytokine pattern to allergic donors, whereas nonallergic individuals were essentially nonreactive.

72 -positive cells in cultures from HLA-DR*0401 nonallergic individuals, even after expansion with IL-2.

73 her alpha-gal-specific IgG1 and IgG3 Ab than nonallergic individuals, whereas the latter showed signi

74 types of APC from birch pollen-allergic and nonallergic individuals.

75 mans, and differ in function in allergic and nonallergic individuals.

76 inct from natural alpha-gal IgG responses in nonallergic individuals.

77 ug of rMal d 1 induced no reactions in three nonallergic individuals.

78 ly higher frequency in allergic infants than nonallergic infants (P < .004); the high fecal count of

79 Levels of human lipocalins are elevated in nonallergic inflammation and cancer, associated with inn

80 rtantly, the repeated cycles of allergic and nonallergic inflammation that comprise chronic human air

81 de effects on lung development, allergic and nonallergic inflammation, and airway remodeling.

82 The (patho)physiological role of IgE in nonallergic inflammatory diseases is not well understood

83 mplicated as a mediator in both allergic and nonallergic inflammatory diseases, including allergic rh

84 tentially contributes to the pathogenesis of nonallergic (intrinsic) asthma and, accordingly, may und

85 dust mites (HDMs) (M+) and 15 nonsensitive, nonallergic (M-) participants completed 3-hour exposures

86 re associated with allergen-specific IgE and nonallergic mechanisms that may coexist in the same pati

87 y epithelium and smooth muscle compared with nonallergic mice, a finding which is replicated in sever

88 influx when infected with RSV compared with nonallergic mice, whereas viral clearance was comparable

89 es thus evokes an allergic state in normally nonallergic mice, which suggests the possibility of neur

90 CF was detected compared to fibroblasts from nonallergic mice.

91 was observed in allergic mice as well as in nonallergic mice.

92 l and macrophage influx and IFN responses in nonallergic mice.

93 , as well as airway hyperreactivity (AHR) in nonallergic mice.

94 nd n-6 PUFAs in breast milk of allergic- and nonallergic mothers and asthma, eczema and sensitization

95 .31-0.79), and more prevalent in children of nonallergic mothers receiving breast milk with higher le

96 gnificantly lower among children of the 8059 nonallergic mothers who consumed more P/TN in their peri

97 cantly lower PKC levels than the children of nonallergic mothers.

98 of 14 years in children of both allergic and nonallergic mothers.

99 tolerant (n = 36) and non-peanut-sensitized nonallergic (n = 25) children underwent skin prick test

100 79), sensitized (n = 40) and nonsensitized, nonallergic (n = 37) infants by multiplex assay.

101 asymptomatic allergic rhinitis (AR), and 11 nonallergic (N).

102 IFN-alpha, P= .004; IFN-lambda1, P= .02) and nonallergic nonasthmatic children (IFN-alpha, P= .002; I

103 dritic cells when compared with that seen in nonallergic nonasthmatic children.

104 h a single early airway reaction (AA-S), and nonallergic nonasthmatic control subjects.

105 teen allergic asthmatic (AA) patients and 18 nonallergic nonasthmatic subjects (healthy volunteers [H

106 e blood of nonasthmatic patients with AR and nonallergic nonasthmatic subjects.

107 ts, 25 nonasthmatic patients with AR, and 19 nonallergic nonasthmatic subjects.

108 SPINK5, and TSLP in asthmatic, allergic, and nonallergic nonasthmatic white and black children partic

109 s allergic rhinitis, infectious rhinitis and nonallergic, noninfectious rhinitis.

110 tantial subgroup of asthmatic patients have "nonallergic" or idiopathic asthma, which often takes a s

111 re measured in tonsil tissue of allergic and nonallergic patients and in peripheral blood of allergic

112 y impulse oscillometry in female late-onset, nonallergic patients with asthma and control subjects be

113 nd, placebo-controlled study of allergic and nonallergic patients with nasal polyps and comorbid asth

114 symptoms were more frequently observed among nonallergic phenotypes as compared with allergic phenoty

115 n to modulate responses to both allergic and nonallergic provocation.

116 hypersensitivity includes allergic (AR) and nonallergic reactions (NARs) influenced by genetic predi

117 unization of mice with PM induces a shift to nonallergic responses and increases the frequency of spl

118 besity was associated with increased odds of nonallergic rhinitis (adjusted odds ratio, 1.43; 95% CI,

119 cts with chronic fatigue syndrome (CFS) with nonallergic rhinitis (n = 14), subjects with active alle

120 ffect the risk of allergic rhinitis (AR) and nonallergic rhinitis (NAR) at 8 years of age.

121 nd development of allergic rhinitis (AR) and nonallergic rhinitis (NAR) between the ages of 8 and 16

122 , the differential diagnosis between LAR and nonallergic rhinitis (NAR) has become a challenge for th

123 Both allergic rhinitis (AR) and nonallergic rhinitis (NAR) patients can elicit nasal hyp

124 tis (AR), the degree of impairment in QoL in nonallergic rhinitis (NAR) remained unknown for a long t

125 Nonallergic rhinitis (NAR) was defined as clinically rel

126 The prevalence of nonallergic rhinitis (NAR) was significantly higher in e

127 llergic rhinitis (AR) with systemic atopy or nonallergic rhinitis (NAR).

128 (rhinitis with sensitization to allergens), nonallergic rhinitis (rhinitis without sensitization), a

129 aeroallergens and the secondary outcomes of nonallergic rhinitis and AR plus asthma.

130 ars, whereas the proportion of children with nonallergic rhinitis decreased slightly over the same pe

131 besity was associated with increased odds of nonallergic rhinitis in adults (adjusted odds ratio, 1.6

132 of patients previously given a diagnosis of nonallergic rhinitis or idiopathic rhinitis are now bein

133 Nonallergic rhinitis was defined as a physician's diagno

134 ng 4- and 8-year-olds, allergic rhinitis and nonallergic rhinitis were associated with asthma, eczema

135 s 12 years of age and older with allergic or nonallergic rhinitis were enrolled in a noninterventiona

136 they were 8 years old; of the children with nonallergic rhinitis, 73% underwent remission during thi

137 obesity is associated with increased odds of nonallergic rhinitis, particularly in male subjects.

138 of breastfeeding were stronger predictors of nonallergic rhinitis, whereas current wheeze and eczema

139 hinitis undergo remission than do those with nonallergic rhinitis.

140 sk factors and severity between allergic and nonallergic rhinitis.

141 an 47% of patients previously diagnosed with nonallergic rhinitis.

142 initis, and differences between allergic and nonallergic rhinitis.

143 ins unclear, and the requirement for BATF in nonallergic settings of type-2 immunity has not been exp

144 er of mucociliary clearance, in allergic and nonallergic sheep.

145 nts with both Th2-type allergic and Th1-type nonallergic sinusitis.

146 ithout birch pollen allergy (group 3), and 5 nonallergic subjects (group 4) by performing skin prick

147 Allergic subjects (n = 6) and nonallergic subjects (n = 4) were treated in season for

148 vus, which tended to have a low frequency in nonallergic subjects (P = .0004).

149 -induced histamine release from basophils in nonallergic subjects and allergen-induced histamine libe

150 RANTES intradermally into both allergic and nonallergic subjects and obtained biopsies 30 min, 6 h,

151 sent at low frequencies in both allergic and nonallergic subjects and reflect classical features of t

152 e grass allergen-specific T cells in DR*0401 nonallergic subjects are present at very low levels (e.g

153 nvolved the production of CCL17 and CCL22 in nonallergic subjects but only CCL17 in allergic patients

154 nonfall birth between (i) food allergic and nonallergic subjects in NHANES, adjusted for ethnicity,

155 DC responses between human food-allergic and nonallergic subjects is necessary to gain a better insig

156 The TCLs of nonallergic subjects mostly secreted IFN-gamma and IL-10

157 f the subjects with alder pollen allergy and nonallergic subjects tested.

158 ch allergy and tolerance to peanut; Group 4, nonallergic subjects that tolerate both peanut and peach

159 mory CD4(+) T-cell responses of allergic and nonallergic subjects to Can f 4.

160 cells (PBMCs) from peanut-allergic (PA) and nonallergic subjects were stimulated (14-16 h) with pean

161 10 age-matched mild-asthmatic and 10 healthy nonallergic subjects were used for comparison.

162 nd were significantly different from healthy nonallergic subjects who had also undergone NAC.

163 placebo) and specificity (very low score in nonallergic subjects) in the GA(2)LEN chamber.

164 ith PA, 77 PS patients, and 43 nonsensitized nonallergic subjects) were studied.

165 in 12 subjects with alder pollen allergy, 6 nonallergic subjects, and 9 allergy vaccine-treated subj

166 B cells from allergic, but not nonallergic subjects, are able to produce IgG4 after cog

167 Likewise, BAT recognized 12 of 14 nonallergic subjects, HR 10, and passive HR 13.

168 for walnut-reactive T cells in allergic and nonallergic subjects, particularly the relationship of p

169 ese diseases and are also present in healthy nonallergic subjects, we performed global transcriptiona

170 inate in allergic subjects but are absent in nonallergic subjects.

171 ave diagnosed asthma or asthma symptoms than nonallergic subjects.

172 o-way crossover studies and an open study in nonallergic subjects.

173 were performed on 11 peanut-allergic and 14 nonallergic subjects.

174 ed more rapidly in allergic subjects than in nonallergic subjects.

175 specific CD4(+) T cells between allergic and nonallergic subjects.

176 old higher frequency from allergic than from nonallergic subjects.

177 to Can f 4 are observed in allergic but not nonallergic subjects.

178 to untreated HCEs or with HCEs treated with nonallergic tears and untreated HCEs (P < 0.05).

179 sed risk from regular smoking was greater in nonallergic than in allergic children.

180 ed histamine release after both allergic and nonallergic triggers.

181 ice displayed the same 50% graft survival as nonallergic WT mice, that was significantly less than th