ライフサイエンスコーパス: nonclassical

1 However, the nonclassical 3-->3 linkages predominate the transpeptide

2 us, to the extent tested, both classical and nonclassical activators work most efficiently when prote

3 his article that KIR3DL2 and KIR2DS4 and the nonclassical Ag HLA-F, expressed as a free form devoid o

4 ted with alternative activation, whereas the nonclassical and classical populations demonstrated an a

5 lammatory phenotype defined by (1) increased nonclassical and intermediate monocytes, (2) a proinflam

6 closely related species to become classical, nonclassical, and nonfunctional.

7 e mechanism of crystallization, classical or nonclassical; and whether quinoline antimalarials inhibi

8 Nonclassical approaches are needed because ions in biolo

9 ied enzymes differed among salt-wasting- and nonclassical-associated variants, but these differences

10 y identified in the components of the HPV is nonclassical because the mean structure of the epitope c

11 riolytic activity in the absence of the CBD (nonclassical behavior).

12 ive to Gaussian statistics--facilitates this nonclassical behavior.

13 altered in optical cavities, often inducing nonclassical behavior.

14 onfirm that aztreonam-like beta-lactams plus nonclassical beta-lactamase inhibitors, particularly avi

15 an be accelerated by MeCN; and complementary nonclassical BH...HN interactions are likely to play a r

16 approach to peptide conjugation based on the nonclassical bioisosteric replacement of the guanidine g

17 emokine receptor 2-dependent manner, and the nonclassical blood resident monocyte subset that patrols

18 IL-6) and activated monocytes (CD14dimCD16+; nonclassical) but not with markers of HIV.

19 binding fragments, including a selection of nonclassical CA II binding chemotypes, were identified.

20 In salt wasting and nonclassical CAH, a phenotype can be attributed to a gen

21 , namely salt wasting, simple virilizing, or nonclassical CAH.

22 outside the context of the virus it induces nonclassical, cancer cell-specific apoptosis.

23 nding of the C3 alkyl chain of classical and nonclassical cannabinoids.

24 ving free radicals, reaction mechanisms, and nonclassical carbocations are discussed.

25 luded proving the occurrence of benzynes and nonclassical carbocations as reaction intermediates, and

26 et al. is based on CH5(+) and Olah's related nonclassical carbonium ion chemistry.

27 as the exclusive site for nuclear import of nonclassical cargos.

28 monocytes with classical CD14(++)CD16(-) and nonclassical CD14(+)CD16(++) monocytes revealed that the

29 l CD14++CD16-, intermediate CD14++CD16+, and nonclassical CD14+CD16++ monocytes.

30 l CD14++CD16-, intermediate CD14++CD16+, and nonclassical CD14+CD16++ monocytes.

31 Nonclassical (CD14(+)CD16(++)) and intermediate (CD14(++

32 CD16(-)), intermediate (CD14(+)CD16(+)), and nonclassical (CD14(dim)CD16(+)) monocytes.

33 CD16(-)), intermediate (CD14(+)CD16(+)), and nonclassical (CD14(dim)CD16(+)) monocytes.

34 6(+) (both intermediate [CD14(+)CD16(+)] and nonclassical [CD14(dim)CD16(+)]) monocytes was increased

35 aracterized by reduced levels of circulating nonclassical CD16(+) monocytes with a poor activation pr

36 he pneumococcal glycolytic enzyme enolase, a nonclassical cell surface and plasminogen-binding protei

37 Interestingly, FACIN is a nonclassical cell surface protein, a cytosolic enzyme ac

38 erentiate sequentially into intermediate and nonclassical cells.

39 ith a distance that is relatively long for a nonclassical CF-HC hydrogen bond.

40 ho-hydrogen to participate in a stabilizing, nonclassical CH...O hydrogen bond with a ring oxygen of

41 Additional stabilizing nonclassical CH...O hydrogen-bond interactions seem to d

42 resynaptic SNARE-complex assembly required a nonclassical chaperone activity mediated by synucleins.

43 Thus, protoadamantyl zwitterion has a less nonclassical character than the corresponding cation, so

44 milar binding affinity on both classical and nonclassical class I molecules.

45 Human and murine MHC nonclassical class Ib-restricted invariant T (iT) cell s

46 Two isostructural, nonclassical Co(H(2)) complexes are prepared from their

47 s one of our examples, we apply STS to check nonclassical correlations among sites in a photosyntheti

48 By measuring strong nonclassical correlations between Raman-scattered photon

49 rmodynamics in relation to the settlement of nonclassical correlations between the wells.

50 hese STS measures enable a new way to assess nonclassical correlations in an open quantum network, su

51 The cationic nonclassical [Cp2ZrN(SiHMe2)2](+) ([2](+)) is prepared f

52 might be reconciled by invoking a three-step nonclassical crystal growth mechanism comprising (i) doc

53 s via both conventional Ostwald ripening and nonclassical crystallization by particle attachment.

54 Cu(2)O nanowire mesocrystals were formed by nonclassical crystallization in the presence of GO and o

55 Although this form of nonclassical crystallization is generally described by o

56 -II involve both classical endolysosomal and nonclassical cytosolic pathways.

57 were identified in a 5-year-old patient with nonclassical DBA and in a 17-year-old patient with myelo

58 Patients with nonclassical DBA and other hypoproliferative anemias may

59 d origin, such as monocytes and classical or nonclassical DCs.

60 In contrast, we find that nonclassical DFG-out conformations strongly select again

61 Nonclassical diagnoses were observed more frequently in

62 support the assignment of these complexes as nonclassical dihydrogen adducts of Co(-I).

63 se had higher event rate than did those with nonclassical disease (hazard ratio for men, 5.63, 95% co

64 Mild nonclassical disease can result from interference in oxi

65 data on the natural course of classical and nonclassical disease in men and women.

66 e had a history of more events than men with nonclassical disease or women with either phenotype; wom

67 ely to develop complications than women with nonclassical disease.

68 These results illustrate how describing nonclassical dopant dynamics requires taking the effecti

69 The present review offers an overview of nonclassical (e.g., with no pre- or in situ activation o

70 E2 in the late stages of pregnancy through a nonclassical E2/ERalpha transrepressive pathway, directl

71 nd promote cellular immunity through diverse nonclassical effector functions.

72 r dynamics techniques to shed light on these nonclassical effects, which are often difficult to inves

73 Simulations reveal three important nonclassical effects: the nucleation free-energy barrier

74 tted NF-kappaB activation, suggesting that a nonclassical EGFR-based signal transduction pathway trig

75 However, the potential for classical versus nonclassical ER signaling to influence hormone sensitivi

76 e noncanonical pathway to assess the role of nonclassical ERalpha signaling in energy homeostasis.

77 These findings indicate that nonclassical ERalpha signaling mediates major effects of

78 In these mice, we found that nonclassical ERalpha signaling restored metabolic parame

79 cue of body weight and metabolic function by nonclassical ERalpha signaling was mediated by normaliza

80 ic process of recombination and propose that nonclassical excision circles are liberated during the f

81 tom and the H6 of the base, reminiscent of a nonclassical F...H hydrogen bond, could be observed.

82 osylsphingosine concentrations than men with nonclassical Fabry disease or women with either phenotyp

83 Individuals with these nonclassical FCGR2C-Stop alleles carried a deletion of F

84 In case of "nonclassical" FCGR2C-ORF alleles, FcgammaRIIc expression

85 We conclude that nonclassical FD is caused by Fpn mutations that decrease

86 We further examine the nonclassical features and energy fluxes implied by the d

87 Nonclassical ferroportin disease (FD) is a form of hered

88 ssical (physicochemical and topological) and nonclassical (fingerprints) molecular descriptors of 138

89 iants associated with either salt-wasting or nonclassical forms of CAH were expressed, purified, and

90 Calculations suggest that the observed nonclassical fullerene could be a kinetically trapped sp

91 Using Xenopus nonclassical gene 10 tetramers and RNAi loss of function

92 equirement of the class Ib molecule, Xenopus nonclassical gene 10, in its differentiation and functio

93 c modulator provides a novel explanation for nonclassical gene regulation by (*)NO.

94 ese effects are unknown, they likely involve nonclassical genetic mechanisms.

95 ore, the GRP88 nuclear localization suggests nonclassical GPCR modes of action of the protein that co

96 at SSZ-13 grows by two concerted mechanisms: nonclassical growth involving the attachment of amorphou

97 The nonclassical H2 adduct is an intermediate in the complet

98 Human leukocyte antigen (HLA)-G is a nonclassical HLA class I molecule expressed as membrane-

99 tifs previously described to be presented on nonclassical HLA class I molecules.

100 The nonclassical HLA molecule MHC-related protein 1 (MR1) pr

101 HLA-G, a nonclassical HLA molecule uniquely expressed in the plac

102 n was circumvented by enforced expression of nonclassical HLA molecules.

103 The classical HLA-C and the nonclassical HLA-E and HLA-G molecules play important ro

104 is study, we present data that implicate the nonclassical HLA-F and open conformers of MHC-I expresse

105 Interestingly, they moderately express nonclassical HLA-G and HLA-E molecules.

106 ereas Ag presentation by classical and other nonclassical HLAs was unaffected.

107 at miR-152 overexpression down-regulates the nonclassical human leukocyte antigen (HLA) class I molec

108 Natural killer (NK) cell recognition of the nonclassical human leukocyte antigen (HLA) molecule HLA-

109 to its periphery, providing hydrophobic and nonclassical hydrogen bonding interactions with the prot

110 stereoselectivity are due to the presence of nonclassical hydrogen bonds between the sulfonamide, the

111 econdary to pyroptotic lysis and in nonlytic/nonclassical IL-1beta export.

112 We report an experimental demonstration of a nonclassical imaging mechanism with super-resolving powe

113 mmunoprecipitation analyses, revealed that a nonclassical importin beta family member, IPO3, was the

114 The clinical presentation was nonclassical in regard to progression, duration, and sev

115 was 0.7% (8/1078) and was 16.7% (9/54) for "nonclassical" indications (peritonitis, carcinomatosis,

116 This effect is mediated through the nonclassical inhibitory G (Galphai/0) protein.

117 articles are therefore expected to exhibit a nonclassical inhomogeneous spectral broadening due to si

118 estrogen response element (ERE) binding and nonclassical (interaction with c-Jun at AP-1 sites) path

119 e the output distribution resulting from the nonclassical interference of photons in an integrated ph

120 previous complexities and the first on-chip nonclassical interference with more than two photonic in

121 , eight spatial modes and many classical and nonclassical interferences.

122 precise FcgammaR repertoire on classical and nonclassical intermediate monocytes--M1 and M2c macropha

123 monocytes cocultures (IL-6(hi)) was added to nonclassical/intermediate monocyte cocultures (TNF(hi)),

124 vels of TNF were detected in cocultures with nonclassical/intermediate monocytes, the blockade of whi

125 )CD16(-) (classical) and CD14(+/dim)CD16(+) (nonclassical/intermediate), have been described.

126 ded species show complex spectra composed of nonclassical ions.

127 characterization, and catalytic activity of nonclassical iron(II) polyhydride complexes containing t

128 llustrate how new samarium(II) complexes and nonclassical lanthanide(II) reagents are changing the la

129 erate and characterize frequency-multiplexed nonclassical light sources for quantum info-communicatio

130 Semiconductors can also be used to generate nonclassical light; in fact, CMOS-compatible silicon chi

131 rived from glioblastoma (GBM) cells involves nonclassical, lipid raft-dependent endocytosis.

132 have uncovered an immunosuppressive role for nonclassical Ly6Clo monocytes that mediates resistance t

133 rized macrophage depletion and inhibition of nonclassical macrophage migration, in addition to direct

134 Cx3cr1(-/-) mice were used to inhibit nonclassical macrophage migration.

135 , in addition to direct interactions between nonclassical macrophages and fibroblasts in angiotensin

136 Human leukocyte antigen-G (HLA-G) is a nonclassical major histocompatibility complex (MHC) clas

137 Here we show that the nonclassical major histocompatibility complex (MHC) clas

138 ntrolled expansion that was dependent on the nonclassical major histocompatibility complex (MHC) prot

139 pocR, suggesting it might regulate pocR in a nonclassical manner.

140 Ab-mediated immunity, while suggesting a new nonclassical mechanism of Ab function, which may apply t

141 ters in the bulk liquid is associated with a nonclassical mechanism of crystal growth and can trigger

142 These nonclassical mechanisms include 1) inhibition of gut DPP

143 ves in Diabetes outlines and discusses these nonclassical mechanisms of DPP-4 inhibition.

144 cules and precursors, bridging classical and nonclassical mechanisms.

145 ive endocytosis (MEND) in BHK fibroblasts by nonclassical mechanisms.

146 ew, we discuss the evidence supporting these nonclassical megakaryocytic differentiation pathways and

147 g frequency is blue-shifted, consistent with nonclassical metal-CO interactions.

148 repertoire presented by classical as well as nonclassical MHC class I (MHC I) molecules is altered in

149 usively, or cross-reacted with classical and nonclassical MHC class I ligands.

150 HLA-G is a nonclassical MHC class I molecule and its physiological

151 ain and recognize lipid Ags presented by the nonclassical MHC class I molecule CD1d are probably the

152 -forming NKG2D, NKG2 receptors recognize the nonclassical MHC class I molecule HLA-E, and they can be

153 IEC express a nonclassical MHC class I molecule known as the thymus le

154 -cell receptor alpha-chain restricted by the nonclassical MHC class I molecule MHC-related protein 1

155 ctivating receptor interacting with HLA-E, a nonclassical MHC class I molecule.

156 mportant positive regulator of classical and nonclassical MHC class I molecules.

157 eign and self-lipids in association with the nonclassical MHC class I-like molecules, CD1 proteins.

158 Nonclassical MHC class Ib (class Ib) genes are heterogen

159 MHC-E is a highly conserved nonclassical MHC class Ib molecule that predominantly bi

160 a highly conserved, ubiquitously expressed, nonclassical MHC class Ib molecule with limited polymorp

161 ariant Valpha6 [iValpha6]) restricted by the nonclassical MHC class Ib molecule XNC10 in the amphibia

162 s indicate that T cells with specificity for nonclassical MHC class Ib molecules may also participate

163 xpress semi-invariant TCR and restriction by nonclassical MHC class Ib molecules.

164 Nonclassical MHC class Ib-restricted invariant T (iT) ce

165 HLA-DM (DM) is a nonclassical MHC class II (MHC II) protein that acts as

166 at were entirely restricted by MHC II or the nonclassical MHC I molecule, MHC-E.

167 d immunogenicity of peptides associated with nonclassical MHC I was increased in the absence of ERAAP

168 s onto MHC II is catalyzed by HLA-DM (DM), a nonclassical MHC II molecule.

169 Mouse CD1d is a nonclassical MHC molecule able to present lipids and gly

170 cificity for viral Ags and yet to be defined nonclassical MHC molecules.

171 l MHC class I and MHC class II molecules and nonclassical MHC-I molecules.

172 lationships, including those associated with nonclassical MHC-I, have yet to be clearly defined.

173 and foreign lipid Ags when presented by the nonclassical MHCI homolog CD1d.

174 HLA-DM, a nonclassical MHCII protein, acts as a peptide exchange c

175 ass II (MHCII) molecules is catalyzed by the nonclassical MHCII-related molecule H2-M.

176 vity in the brain, much of which can involve nonclassical modes of neuronal firing and integration.

177 tment to the site of injury, implicating the nonclassical monocyte in this process.

178 ed using highly purified human classical and nonclassical monocyte subsets from a clinical cohort, al

179 )/CD16(+) intermediate and CD14(low)/CD16(+) nonclassical monocyte subsets in peripheral blood mononu

180 , mice that have markedly reduced numbers of nonclassical monocytes (CX3CR1(-/-)) exhibited a signifi

181 ediate monocytes [IM]), and CD14(+)CD16(2+) (nonclassical monocytes [NCM]).

182 an) can define slan-positive CD14(+)CD16(++) nonclassical monocytes and slan-negative CD14(++)CD16(+)

183 tribution of these monocyte subsets with the nonclassical monocytes being expanded (almost 2-fold) in

184 d hierarchical clustering, the slan-positive nonclassical monocytes cluster with monocytes and are cl

185 ly higher baseline peripheral frequencies of nonclassical monocytes compared with nonresponder patien

186 The viral DNA level in nonclassical monocytes correlated with the viral DNA lev

187 deposition were generated for classical and nonclassical monocytes defining enhanceosomes of the 2 m

188 ytes predicted the primary endpoint, whereas nonclassical monocytes did not (p = 0.158).

189 CCR5, was higher, and a higher proportion of nonclassical monocytes expressed CCR1, CXCR3, and CX3CR1

190 riming them for anaerobic energy production, nonclassical monocytes expressed higher levels of oxidat

191 Intermediate and nonclassical monocytes have longer circulating lifespans

192 classical monocytes and neutrophils, but not nonclassical monocytes in a formyl-peptide receptor-depe

193 ons, similar to classical, intermediate, and nonclassical monocytes in humans, based upon CD14 and CD

194 e adhesion of classical monocytes but not of nonclassical monocytes in the mouse cremaster muscle and

195 Our data suggest a critical role for nonclassical monocytes in the pathology of TBI in mice,

196 rected migration of inflammatory but not for nonclassical monocytes into the liver.

197 Subsequent labeling of intermediate and nonclassical monocytes is consistent with a model of seq

198 reen fluorescent protein) mice, we show that nonclassical monocytes patrol inside healthy carotid art

199 scular space in resting organs, and Ly6c(lo) nonclassical monocytes patrol the vasculature.

200 gage ex vivo FcgammaRIIIA (CD16)-expressing, nonclassical monocytes resulting in ADCC-mediated lysis

201 d become infected and the number of infected nonclassical monocytes that transmit virus to CD4(+) and

202 intermediate monocytes are more likely than nonclassical monocytes to migrate to the lesion site.

203 Nonclassical monocytes undergo intravascular patrolling

204 ial patrolling is a prominent new feature of nonclassical monocytes with unique molecular and kinetic

205 nocyte subsets (classical, intermediate, and nonclassical monocytes) to the total viral burden in 22

206 F(V600E) was tracked to classical monocytes, nonclassical monocytes, and CD1c(+) myeloid dendritic ce

207 Both classical and nonclassical monocytes, but not CD1c(+) DCs, made foamy

208 sical and intermediate monocytes, but not in nonclassical monocytes, which nonetheless display a very

209 f viral DNA in CD8(+) and CD4(+) T cells for nonclassical monocytes.

210 T1 phosphorylation in fetal intermediate and nonclassical monocytes.

211 RATIONALE: Nonclassical mouse monocyte (CX3CR1(high), Ly-6C(low)) p

212 Nonclassical nanotube end-caps have been constructed fro

213 Furthermore, a nonclassical negative-binomial model was shown to correc

214 cales via both classical spike-dependent and nonclassical neuropeptide-dependent mechanisms.SIGNIFICA

215 Previous studies have implicated nonclassical NF-kappaB as a pathway important in the dev

216 sistance can occur through activation of the nonclassical NF-kappaB pathway and acquired resistance m

217 B-cell receptor and JAK/STAT signaling, the nonclassical NF-kappaB pathway, cell-cycle regulation, a

218 associated factor 3 (TRAF3), an inhibitor of nonclassical NF-kappaB signaling.

219 nt B cells, with downstream loss of MAPK and nonclassical NF-kappaB signaling.

220 n mTEC development mediated by inhibition of nonclassical NF-kappaB.

221 The larger Ga and In ions stabilize rare, nonclassical Ni-H2 adducts that catalyze olefin hydrogen

222 d bind to importin alpha1, STAT1 possesses a nonclassical NLS recognized by the isoform importin alph

223 Here we show that a nonclassical nuclear import pathway via IPO3 (importin 3

224 In the complex, eVP24 recognizes a unique nonclassical nuclear localization signal (NLS) binding s

225 responsible for nuclear localization, and a nonclassical nuclear localization signal (NLS) was mappe

226 dict that low coordination numbers result in nonclassical nucleation behavior, which we find to be es

227 These new pathways include the so-called nonclassical nucleation mechanism via the assembly of th

228 ecursor and could therefore be an example of nonclassical nucleation.

229 The nonclassical open reading frame in the FCGR2C gene (FCGR

230 g of classic, proinflammatory monocytes into nonclassical or alternative monocytes to facilitate prop

231 3213128 (compound 28a), a novel, selective, nonclassical, orally bioavailable antifolate with potent

232 a concise regiodivergent asymmetric route to nonclassical P-stereogenic 5- or 6-membered benzophospha

233 (and activity) of fatty acid synthase via a nonclassical pathway dependent on activated Stat3.

234 Tat activated T cells through a nonclassical pathway dependent upon vascular endothelial

235 rgos, and we raise the possibility that this nonclassical pathway is shared by most AAV variants, reg

236 ching ER signaling from the classical to the nonclassical pathway leading to increased hormone sensit

237 1B10 is secreted through a lysosome-mediated nonclassical pathway, leading to an increase in the seru

238 silica molecules as primary growth units and nonclassical pathways based on the aggregation of metast

239 s are either known or postulated to grow via nonclassical pathways involving the initial self-assembl

240 The particles involved in these nonclassical pathways to crystallization are diverse, in

241 The frequency of nonclassical patrolling monocytes is increased in HTLV-1

242 tumorigenesis and cancer metastasis, but how nonclassical "patrolling" monocytes (PMo) interact with

243 or proinflammatory (CCR2(hi)CX3CR1(low)) and nonclassical, patrolling, or alternative (CCR2(low)CX3CR

244 In this article, we demonstrate that the nonclassical peroxisome proliferator 4-phenyl butyric ac

245 uantum optics, being the trigger of multiple nonclassical phenomena.

246 simple virilizing phenotypes or with milder nonclassical phenotypes.

247 mechanistic information, aimed at developing nonclassical platinum complexes that operate via mechani

248 We then describe approaches that explore nonclassical platinum(II) complexes with trans geometry

249 s and the lectin-like receptor CD94-NKG2A by nonclassical pMHC-I complexes, in each case leading to n

250 monocytes, and there is no CD14(-) CD16(+) "nonclassical" population.

251 ss I proteins are divided into classical and nonclassical proteins.

252 four plant PUFs results in a preference for nonclassical PUF RNA target sequences.

253 Thus, nonclassical Qa-1(b)-peptide complexes direct cytotoxic

254 costimulation of the CRF and the surrounding nonclassical receptive field (nCRF) increases neuronal r

255 count for a large range of V1 classical, and nonclassical, receptive field properties including orien

256 CD4(+) T cells suggests that a transition to nonclassical regulatory T cells precedes and is retained

257 tive to conventional designs, as well as new nonclassical resonant mode shapes.

258 Thus, nonclassical retinal photoreception occurs within divers

259 ignaling pathway involves the synthesis of a nonclassical retinoid.

260 dehydrogenases leading to the synthesis of a nonclassical retinoid.

261 with transduction efficiency and relies on a nonclassical retrograde transport pathway that is indepe

262 Recently, nonclassical roles for GRK2 in cardiovascular disease ha

263 In this review, classical and nonclassical roles for GRK2 will be discussed, focusing

264 Ph)(3)]Ru(mu-H)(3)SiRR'(base), feature three nonclassical Ru-H-Si interactions and hexacoordinate sil

265 The nonclassical ruthenium hydride pincer complex [Ru(PNP)(H

266 Plt20/Plt20) and Mpl(-/-)), which implicates nonclassical secretion from nucleated cells as the sourc

267 The Vid pathway is linked to the nonclassical secretory and internalizing pathways.

268 ss potential functions of both classical and nonclassical sHLA-I, using soluble recombinant HLA-I/pep

269 r DFT calculations reveal the formation of a nonclassical sigma-hole region with one or even two maxi

270 At the limit, the tuning transforms the nonclassical sigma-hole regions into coordination sites,

271 A major section on nonclassical (sigma or agostic) complexes includes two g

272 NEDD4 C2 binds at nonclassical sites on the SH2 domain surface, far from t

273 living materials can be expected to provide nonclassical solutions in consumer goods such as packagi

274 Although a nonclassical state from spontaneous parametric down-conv

275 Squeezed states of light are a set of nonclassical states in which the quantum fluctuations of

276 a rare phenomenon otherwise known only from nonclassical states of light like the squeezed vacuum.

277 trasensitive measurements of weak forces and nonclassical states of motion.

278 linking steroidogenesis in CD8(+) T cells, a nonclassical steroidogenic tissue, to a proallergic diff

279 expressed EGFP, with increased levels in the nonclassical subset.

280 LR) agonists in classical, intermediate, and nonclassical subsets of monocytes by assessing intracell

281 subdivided into classical, intermediate, and nonclassical subsets, but there is no unequivocal strate

282 f the receptive field and the ability of the nonclassical surround mechanism to attenuate this.

283 erapy agents and humanized mAbs present with nonclassical symptoms of anaphylaxis, and patients may p

284 RNA (siRNA) knockdown studies suggested that nonclassical targets of sorafenib are important for the

285 These ex-Th17 cells are also called nonclassical Th1 cells because of their ability to produ

286 kingly, induced marked production of diverse nonclassical TH2 inflammatory mediators, including IL-22

287 allergy, regulatory immune cell subsets and nonclassical Th2-biased inflammatory mediators in the tu

288 dependently of IFN-gamma and IL-17; however, nonclassical Th22 cells have been recently identified an

289 Three nonclassical Th22 subsets constituted the majority of al

290 most efficiently triggered the expansion of nonclassical Th22 subsets from memory T cells and classi

291 Little is known about how classical and nonclassical Th22 subsets in human diseases are regulate

292 al by examining a set of activators (called "nonclassical") that lack activating regions.

293 three subsets (classical, intermediate, and nonclassical) that circulate in dynamic equilibrium.

294 Our findings are independent of the specific nonclassical theory used, thus providing important insig

295 a dramatic decrease of classical (H-2K) and nonclassical (Tla) MHC-I expression by T/B lymphocytes,

296 dulation are reviewed, with special focus on nonclassical TLR4 ligands with a chemical structure diff

297 Our data demonstrate that both classical and nonclassical trans-repression mechanisms account for NR-

298 onse and further define the "classical" and "nonclassical" types of antibody inhibitors against the f

299 med) [intermediate], and CD14(neg)/CD16(hi) [nonclassical]) were examined at homeostasis and after ac

300 ation of cells (classical, intermediate, and nonclassical) with distinct functions, however, the recr