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1 ys should reveal new biological functions of noncoding RNA.
2 within RP1-13D10.2, an uncharacterized long noncoding RNA.
3 t RNA pathways for processing the host's own noncoding RNA.
4 he oxidative stress response by an oncogenic noncoding RNA.
5 aryotes may have such enzymes for processing noncoding RNA.
6 Most of these loci encoded long noncoding RNAs.
7 ranscribes all protein-coding genes and many noncoding RNAs.
8 s the formation and biological activities of noncoding RNAs.
9 es transcription of protein-coding mRNAs and noncoding RNAs.
10 nt paradigm for chromatin regulation by long noncoding RNAs.
11 major effort to therapeutically target these noncoding RNAs.
12 of genes, gene regulatory regions, and long noncoding RNAs.
13 ripts, ignoring the important impact of long noncoding RNAs.
14 f regulatory RNAs and their binding sites in noncoding RNAs.
15 plex (NoRC) that regulates the expression of noncoding RNAs.
16 ding genes, and 567 putative long intergenic noncoding RNAs.
17 e posttranslational modifications, and small noncoding RNAs.
18 immune systems and the diverse functions of noncoding RNAs.
19 nonsense suppressor tRNAs and/or regulatory noncoding RNAs.
21 dopsis mRNAs, long noncoding RNAs, and other noncoding RNAs across three tissue types (siliques, seed
22 hard-to-treat cancers by targeting oncogenic noncoding RNAs, advancing a disease-to-gene-to-drug para
25 on for a long time, it has become clear that noncoding RNAs also play key roles in cardiac fibrosis.
26 nes, regulating oncogenic gene expression by noncoding RNA and miRNA editing, or by transcriptome sca
27 cies of this kind of Pol III-dependent viral noncoding RNA and the first noncoding RNA identified in
28 xtended 3' UTRs have characteristics of long noncoding RNAs and likely do not interact with miRNAs.
29 enes and their non-coding RNA partners, long noncoding RNAs and microRNAs, provided valuable insight
30 ring the critical regulatory roles played by noncoding RNAs and noncoding regions of the genome durin
31 c data collection and curation), data types (noncoding RNAs and protein-coding genes) and content acc
32 lted in the loss of m(5)C sites on mRNAs and noncoding RNAs and reduced the stability of tRNA(Asp(GTC
33 agenesis to obtain induction of an arbitrary noncoding RNAs, and coupled it with a cell based loss-of
34 profiles of mRNAs, primary micro-RNAs, long noncoding RNAs, and enhancer RNAs in a large animal mode
35 altering protein-coding sequences, producing noncoding RNAs, and even supporting evolution of new pro
37 clude DNA methylation, histone modification, noncoding RNAs, and mitotic gene bookmarking play pivota
38 usand m(5)C sites in Arabidopsis mRNAs, long noncoding RNAs, and other noncoding RNAs across three ti
41 whether changes in the serum levels of these noncoding RNAs are observed in patients with asymptomati
44 of functionally related pairs of circulating noncoding RNAs as biomarkers in cardiovascular disease.
46 bilize deleterious secondary DNA structures, noncoding RNA associated DNA/RNA hybrid formation, and p
47 onal HBoV1 gene, bocavirus-transcribed small noncoding RNA (BocaSR), within the 3' noncoding region (
49 ions of RNA bases are not only found in many noncoding RNAs but have also recently been identified in
50 not only the levels of both mRNAs and small noncoding RNAs, but also their cytoplasmic compartmental
52 mmalian cells, the formation of a 3' end for noncoding RNAs can be a complex process governed by the
57 re, we identify an Arabidopsis thaliana long-noncoding RNA, designated ELF18-INDUCED LONG-NONCODING R
59 ents in differential gene expression data or noncoding RNA discovery, as well as allow genome-scale a
60 hape, but it's clear that in both coding and noncoding RNAs, dynamic modifications represent a new la
61 regulatory elements, such as miRNAs and long noncoding RNAs, either enhancing or diminishing their re
62 by ischemia, including novel conserved long noncoding RNAs expressed in antisense orientation to myo
64 NA custom-made array we identified CDF5 LONG NONCODING RNA (FLORE), a circadian-regulated lncRNA that
65 ves as a sponge or as a competing endogenous noncoding RNA for miR-150, restricting its capability to
67 ough microRNAs (miRNAs) are a class of small noncoding RNAs frequently deregulated in various human m
68 to the SET1 mRNA, Ty1 retrotransposons, and noncoding RNAs from the ribosomal DNA (rDNA) intergenic
72 red for transcriptional termination of short noncoding RNA genes and for a fail-safe transcriptional
76 ng anti-apoptotic potential, suggesting that noncoding RNAs have an impact on the pathogenesis of hum
78 the identification of a human-specific long noncoding RNA, Heart Brake LncRNA 1 (HBL1), which regula
80 -dependent viral noncoding RNA and the first noncoding RNA identified in autonomous parvoviruses.
83 tal resource to deepen our knowledge on long noncoding RNAs in C3 cereals, allowing the Brachypodium
85 cusses the involvement of microRNAs and long noncoding RNAs in cardiac fibrosis and summarizes the is
86 nificance and mechanisms of other classes of noncoding RNAs in cerebrovascular pathophysiology after
87 idence implicates both enhancer elements and noncoding RNAs in controlling this spatiotemporal expres
89 n, the biological significance of pathogenic noncoding RNAs in host-pathogen interactions remains lar
90 rature on the role of miRNAs and other small noncoding RNAs in platelets and in the circulation, and
92 plore translational regulation of coding and noncoding RNAs in roots of Arabidopsis thaliana shifted
93 r studies evaluating the function of various noncoding RNAs in the brain, including noncoding RNAs th
94 these studies demonstrate the importance of noncoding RNAs in the regulation of HSC and LSC function
95 ese stress-induced 3' UTR extensions as long noncoding RNAs in the regulation of their neighboring ge
96 tional layer of complexity, implicating long-noncoding RNAs in the transcriptional regulation of plan
98 coding genes, mutations and misregulation of noncoding RNAs, in particular long noncoding RNAs (lncRN
99 rovide strong evidence for the importance of noncoding RNAs, in particular, miRNAs, in hepatic dediff
100 Little has been known about the role of noncoding RNAs, including microRNAs (miRNAs), in predisp
101 DNA methylation, and (iii) up-regulation of noncoding RNAs, including microRNAs, with concomitant do
104 ortant functions in the 3'-end processing of noncoding RNAs, including the uridine-rich small nuclear
105 e some work has demonstrated that pathogenic noncoding RNAs interact with host factors for function,
106 se that integrating our current knowledge of noncoding RNA into a quantitative biochemical and theore
107 feedback loops based on recently identified noncoding RNAs introduce additional layers of complexity
110 ng RNA (lncRNA) Flicr (Foxp3 long intergenic noncoding RNA) is a negative regulator that tunes Foxp3
111 ted lncRNA which we named PINCR (p53-induced noncoding RNA), is induced 100-fold after DNA damage an
113 ion signal in the 1q42.2 locus ( TSNAX-DISC1 noncoding RNA, lead single-nucleotide polymorphism: rs14
114 ression patterns with other genes, including noncoding RNA LINC01124 and uncharacterized RNA AK127400
121 ng RNAs, a growing number of long intergenic noncoding RNAs (lincRNAs) have been described in multice
124 an additional layer of complexity, the long noncoding RNA (lncRNA) Flicr (Foxp3 long intergenic nonc
125 mplicated in thyroid development, and a long noncoding RNA (lncRNA) gene, papillary thyroid cancer su
126 hism (SNP) located in the intron of the long noncoding RNA (lncRNA) LINC00305 by searching the GWAS d
127 r, the Hoxd antisense growth-associated long noncoding RNA (lncRNA) located between Hoxd1 and Hoxd3 I
130 dentified RACER, a novel Tbx5-dependent long noncoding RNA (lncRNA) required for the expression of th
131 timulates the transcription of DANCR, a long noncoding RNA (lncRNA) that is widely overexpressed in h
132 eric repeat-containing RNA (TERRA), the long noncoding RNA (lncRNA) transcribed from telomeres, have
133 y was designed to determine the role of long noncoding RNA (lncRNA), metastasis-associated lung adeno
140 YC Accumulating evidence indicates that long noncoding RNAs (lncRNA) contribute to the stem-like char
142 lation of noncoding RNAs, in particular long noncoding RNAs (lncRNA), appear to play major roles in c
143 onary disease (COPD) development, while long noncoding RNA (lncRNAs) have been shown to cause COPD.
157 ibitor JQ1, or knockdown of overlapping long noncoding RNAs (lncRNAs) blocks AngII-induced genes asso
158 ies have demonstrated the importance of long noncoding RNAs (lncRNAs) during oncogenic transformation
159 The discovery of functional classes of long noncoding RNAs (lncRNAs) has expanded our understanding
169 Increasing evidence indicates that long noncoding RNAs (lncRNAs) have important roles in various
171 file mRNAs and both annotated and novel long noncoding RNAs (lncRNAs) in human naive, central memory,
173 human cells, little is known about how long noncoding RNAs (lncRNAs) interact with target loci in th
176 ory RNAs such as microRNAs (miRNAs) and long noncoding RNAs (lncRNAs) play crucial roles in the devel
177 easing evidences have demonstrated that long noncoding RNAs (lncRNAs) play important roles in many hu
181 d co-activation and accumulation of the long noncoding RNAs (lncRNAs) XACT and XIST on active X chrom
182 iated dysregulation of primate-specific long noncoding RNAs (lncRNAs), downregulation of the alternat
184 scriptome profiles, including mRNAs and long noncoding RNAs (lncRNAs), in skeletal muscle of rainbow
185 ntain thousands of loci that transcribe long noncoding RNAs (lncRNAs), some of which are known to car
186 he functional effects of RNA editing in long noncoding RNAs (lncRNAs), we systematically analyzed the
187 tion and a locus regulating hippocampal long noncoding RNAs (lncRNAs), whose expression correlates wi
188 The human genome produces thousands of long noncoding RNAs (lncRNAs)-transcripts >200 nucleotides lo
196 A polymerase III (Pol III) synthesizes short noncoding RNAs, many of which are essential for translat
198 omoter, we propose that this cis-constrained noncoding RNA-mediated mechanism limiting the duration o
199 veries, including the identification of long noncoding RNAs, microDNAs, a family of small extrachromo
200 ally compare the functions of a large set of noncoding RNA modifications in gene regulation, we carri
202 roRNAs represent a promising class of small, noncoding RNA molecules that function to regulate gene e
203 croRNAs (miRNAs) are highly conserved, small noncoding RNA molecules that negatively regulate gene ex
207 The increased expression of miR-323-3p and noncoding RNA nc886 and reduced expression of miR-93, mi
208 tion of transcriptomes and identification of noncoding RNA (ncRNA) classes has been greatly facilitat
210 polymerase III, thus generating exclusively noncoding RNA (ncRNA) that must hijack the machinery req
211 s studies have identified several classes of noncoding RNAs (ncRNA) also associated with aging-relate
213 gulation of enhancer and promoter associated noncoding RNAs (ncRNAs) could stabilize deleterious seco
215 mature transfer RNAs (tRNAs) and other small noncoding RNAs (ncRNAs) encapsulated within vesicles.
221 Increasing data support the importance of noncoding RNAs (ncRNAs), including microRNAs (miRNAs) an
226 lta, E., De Strooper, B. microRNA-132: a key noncoding RNA operating in the cellular phase of Alzheim
227 n differentiation, while knockdown of a long noncoding RNA overlapping E1 has no detectable effect on
228 y, we tested the use of functionally related noncoding RNA pairs to enhance the discriminatory power
229 lex network comprising a promoter-associated noncoding RNA (paRNA), microRNA and epigenetic regulator
230 nd the Bapx2/Nkx3-2 homolog Nkx3-1, the long-noncoding RNA PEAT (Pax1 enhancer antisense transcript)
231 molecule in the information network, whilst noncoding RNAs perform additional diverse functions.
232 roid (PSTVd) is a circular, single-stranded, noncoding RNA plant pathogen that is a useful model for
234 f RNA helicase Mtr4 (and senataxin) with the noncoding RNA processing function of RNA exosome determi
235 rotein involved in this process as well as a noncoding RNA produced by alternative processing of RNA
237 The sequence and expression specificity of noncoding RNA promoters are evolutionarily conserved, im
239 genome is transcribed into a broad array of noncoding RNAs, ranging in size from microRNA (20-23 nuc
244 expression of TOX2 and a brain-specific long noncoding RNA RP1-269M15.3 in frontal cortex and nucleus
245 types of all classes of RNAs, including long noncoding RNAs, several of which were confirmed as highl
250 analysis lacks in sensitivity to detect all noncoding RNA species and does not provide separation be
252 tein-coding transcripts; and (4) twenty long noncoding RNAs specifically responsive to TRV vectors.
253 otein and RNA chaperone Hfq stabilizes small noncoding RNAs (sRNAs) and facilitates their annealing t
254 t DNA repeats involves the activity of small noncoding RNAs (sRNAs) associated with the RNA interfere
256 in cancer maintenance, many of which include noncoding RNAs such as microRNA (miR)-210 that regulates
258 Although piRNAs and other classes of small noncoding RNAs, such as miRNAs and small interfering (si
261 r findings reveal BocaSR to be a novel viral noncoding RNA that coordinates the expression of viral p
262 e demonstrate a novel role of Malat1, a long noncoding RNA that has been originally identified as a p
263 oliferation by identifying an oncogenic long noncoding RNA that is widely overexpressed in human canc
264 thelial cells and mice, we identified uc.173 noncoding RNA that regulates growth of the intestinal mu
266 S-adenosylmethionine (SAM)-I riboswitch is a noncoding RNA that regulates the transcription terminati
268 ble tool for functional studies of essential noncoding RNAs that are resistant to RNAi and RNase H-ba
273 ymerases, Pol IV and Pol V, which synthesize noncoding RNAs that coordinate RNA-directed DNA methylat
274 miRNAs are evolutionarily conserved small noncoding RNAs that display important physiological effe
275 expression from loci that produce regulatory noncoding RNAs that function within the nucleus; however
276 s (circRNAs) represent a class of endogenous noncoding RNAs that have recently been recognized as imp
277 rious noncoding RNAs in the brain, including noncoding RNAs that may play a role in psychiatric disea
280 croRNAs (miRNAs) constitute a class of small noncoding RNAs that plays an important role in the post-
285 nd ASAR15 are monoallelically expressed long noncoding RNAs that remain associated with the chromosom
286 gest that noncanonical Dicer generates small noncoding RNA to mediate the DNA damage response (DDR).
289 e the designation of more than 87 predicted "noncoding RNAs" to conventional mRNAs coded by protein-c
294 approaches to advance understanding of long noncoding RNAs, we investigate the function of the telom
296 tivation, leading to degradation of H19 long noncoding RNA, which normally binds to and inactivates S
299 ive, allowing the identification of numerous noncoding RNAs with key roles in biological processes.
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