ライフサイエンスコーパス: noncompetitively

1 e receptor's regulatory site and inhibits it noncompetitively.

2 which BMP4 inhibits Tolloid enzyme activity noncompetitively.

3 of STR, suppressed both the peak and SS IGly noncompetitively.

4 ferin, whereas myristyl alcohol inhibited it noncompetitively.

5 mma and G(t betagamma) bind to G(t alpha)GDP noncompetitively.

6 the apical and C-terminal regions of AgI/II noncompetitively adhere.

7 (rho-TIA) was shown previously to antagonize noncompetitively alpha(1B)-adrenergic receptors (ARs).

8 Despite inhibiting noncompetitively, an AsnEDA inhibitor binds the active s

9 duct inhibition studies, thymidine inhibited noncompetitively and inorganic phosphate inhibited compe

10 of endocytosis, the actin cytoskeleton, acts noncompetitively as a modulator of clathrin function.

11 ribed by a model in which MMOR and MMOB bind noncompetitively at distinct interacting sites on the hy

12 Ibogaine noncompetitively blocked (IC50 approximately 20 nM) 22Na

13 uggest that CL-20 initiated neurotoxicity by noncompetitively blocking the ligand-gated GABA(A) recep

14 ntrations to sustain transport, is inhibited noncompetitively by 5-HT, and is more sensitive to SERT

15 complexes, regulate this enzymatic activity noncompetitively by binding at a site distinct from the

16 trans-Dimethyldiazene reduction is inhibited noncompetitively by CO and C2H2 with Ki values of ca. 0.

17 ties, inhibited serotonin transporter (SERT) noncompetitively by decreasing V(max) with little change

18 olipid hydroperoxide substrate was inhibited noncompetitively by mercaptosuccinate with K(i) 4 miroM.

19 it proteolytic activities of gamma-secretase noncompetitively by unknown mechanisms.

20 ocking of the receptor with transferrin (Tf) noncompetitively, i.e., independently of receptor occupa

21 epopulating function either competitively or noncompetitively in irradiated hosts.

22 PK11195 and CSA bind noncompetitively in Pgp-expressing cells, indicating tha

23 Compound 1 acts noncompetitively in Schild analysis.

24 hown to inhibit serotonin transporter (SERT) noncompetitively, in contrast to all other known inhibit

25 one selected peptide specifically binds and noncompetitively inactivates DNA-PKcs, a protein kinase

26 ythroidine inhibits morantel-evoked currents noncompetitively, indicating that morantel does not bind

27 physiological concentrations of nicotinamide noncompetitively inhibit both Sir2 and SIRT1 in vitro.

28 lpha1A- and alpha1B-adrenergic receptors and noncompetitively inhibit receptor activation by the endo

29 conditions, it can competetively inhibit or noncompetitively inhibit the enzyme.

30 asures of S1P(1) activation by CYM-5442 were noncompetitively inhibited by a specific S1P(1) antagoni

31 PlsY was noncompetitively inhibited by palmitoyl-CoA.

32 mology experiments verify that the enzyme is noncompetitively inhibited by resorufin.

33 [(3)H]PN200 binding to skeletal membranes is noncompetitively inhibited by TCS in the same concentrat

34 nt competitively inhibited MgATP binding and noncompetitively inhibited Fru-6-P binding.

35 peptide containing residues 311-325 (VP311) noncompetitively inhibited prothrombin activation by fac

36 ch as GTP and GDP, as well as pyrophosphate, noncompetitively inhibited sAC.

37 zolo[ 4,5-c]pyridin-4(5H)-one (MMPIP), which noncompetitively inhibited the activity of orthosteric a

38 ced by the methylation of catecholestrogens, noncompetitively inhibited the O-methylation of 2- and 4

39 GFZ noncompetitively inhibited this L. pneumophila FabI homo

40 Ibogaine noncompetitively inhibited transport by both SERT and th

41 ubsequent VLDL/LDL secretion by directly and noncompetitively inhibiting hepatocyte diacylglycerol ac

42 inhibition in binding to beta-tubulin, while noncompetitively inhibiting the binding of vinblastine a

43 resembles most other antimitotic peptides in noncompetitively inhibiting the binding of vinblastine t

44 Thus rho-TIA noncompetitively inhibits alpha(1B)-ARs but competitivel

45 Addition of 10 microM MnCl2 noncompetitively inhibits DPC photooxidation at the high

46 TPSF noncompetitively inhibits estrogen-dependent ERalpha-med

47 We further show that P-CoA noncompetitively inhibits mitochondrial ADP transport an

48 a photoactivatable analogue of octanol that noncompetitively inhibits nicotinic acetylcholine recept

49 Overall, we conclude that DPA noncompetitively inhibits NMDA-induced current by a nove

50 tricyclic antidepressant (TCA) clomipramine noncompetitively inhibits substrate uptake.

51 Individual cells noncompetitively internalize both stimulatory and suppre

52 t studies indicated that most inhibitors act noncompetitively or uncompetitively versus substrate in

53 peripheral nicotinic acetylcholine receptors noncompetitively, primarily via an open-channel block me

54 creening hits appear non-drug-like: they act noncompetitively, show little relationship between struc

55 ies revealed that these compounds inhibit RT noncompetitively, through a new mechanism via closing of

56 A and ribosomes are bound simultaneously and noncompetitively to a common set of inactive translocons

57 structurally diverse set of drugs, which act noncompetitively to perturb normal RT function.

58 etitively when paraoxon is the substrate and noncompetitively when VX is the substrate.

59 Aptamer xPSM-A9 inhibits PSMA noncompetitively with an average K(i) of 2.1 nM, whereas

60 of Cdc25A protein phosphatase reversibly and noncompetitively with an IC(50) value of 2.2 microM.

61 nesthetics inhibited it in millimeter ranges noncompetitively with luciferin.

62 trast, AMP weakly inhibits the basic isozyme noncompetitively with respect to all substrates.

63 f phytohemagglutinin (PHA) activated T cells noncompetitively with respect to cytokine by blocking th

64 previously characterized as inhibiting 3HNR noncompetitively with respect to its naphthol substrate.

65 tively with respect to ATP concentration and noncompetitively with respect to luciferase concentratio

66 ovel NS5B inhibitor that binds to the enzyme noncompetitively with respect to nucleotide substrates.

67 hydroxysteroids, 3beta-hydroxysteroids acted noncompetitively with respect to potentiating steroids a

68 ta5 complexes and Gbetagamma dimers interact noncompetitively with the intracellular domain of GIRK c

69 Mechanistically, PA inhibited the enzyme noncompetitively with the kinetics of a tight binding in

70 Cocaine inhibits the receptor noncompetitively, with an apparent KI of 84 and 26 micro