ライフサイエンスコーパス: nonenveloped

1 es were considered to be either enveloped or nonenveloped.

2 Rotaviruses (RVs) are nonenveloped, 11-segmented, double-stranded RNA viruses

3 We examine virus maturation of selected nonenveloped and enveloped single-stranded RNA viruses,

4 Regulated structural transitions within nonenveloped and enveloped viruses are necessary for acc

5 mportant receptors that have been usurped by nonenveloped and enveloped viruses for attachment and/or

6 Cellular entry of nonenveloped and enveloped viruses is often accompanied

7 PaV particles are isometric, nonenveloped, and about 30 nm in diameter.

8 ronic infections, and that are nonsegmented, nonenveloped, and, most importantly, not transmitted by

9 the capsid of a cytoplasmically replicating nonenveloped animal virus despite the normally reducing

10 ring cell entry by this structurally complex nonenveloped animal virus.

11 sion, is not well characterized for any such nonenveloped animal virus.

12 r details of membrane penetration by a large nonenveloped animal virus.

13 Nonenveloped animal viruses must disrupt or perforate a

14 Several nonenveloped animal viruses possess an autolytic capsid

15 Cell entry by nonenveloped animal viruses requires membrane penetratio

16 The mechanisms employed by nonenveloped animal viruses to penetrate the membranes o

17 ration pathway, which may be shared by other nonenveloped animal viruses.

18 mbrane penetration shared by several diverse nonenveloped animal viruses.

19 The nonenveloped astroviruses and noroviruses similarly show

20 enveloped viruses (MHV and varphi6) and two nonenveloped bacteriophages (MS2 and T3) in raw wastewat

21 sful manipulation of a segmented genome of a nonenveloped capsid virus by the introduction of tags th

22 lumen, HSV-bearing organelles also displayed nonenveloped capsids attached to their cytoplasmic surfa

23 Extracellularly, the interaction of nonenveloped capsids with several host cell proteins, af

24 f HBV virions, but not subviral particles or nonenveloped capsids, through the induction of tetherin

25 the secretion of HBV subviral particles and nonenveloped capsids.

26 Papillomaviruses are epitheliotropic, nonenveloped, circular, double-stranded DNA viruses with

27 ential for transferable application to other nonenveloped complex viruses.

28 on DNA; and (iii) a significant reduction of nonenveloped core particles in the medium.

29 uninfected or adenovirus serotype 5 (Ad5) (a nonenveloped cytolytic virus)-infected Huh7.5.1 cells by

30 Papillomaviruses are a family of nonenveloped DNA tumor viruses.

31 BKPyV is a nonenveloped DNA virus that must traffic through the end

32 llomaviruses (PV) comprise a large family of nonenveloped DNA viruses that include the oncogenic PV t

33 risk human papillomaviruses (HPVs) are small nonenveloped DNA viruses with a strict tropism for squam

34 AdVs, which have the largest genome of nonenveloped DNA viruses, are being extensively explored

35 rus infection have not been defined for this nonenveloped double-stranded DNA (dsDNA) virus.

36 Bluetongue virus (BTV), a nonenveloped double-stranded RNA virus, is a potent indu

37 Mammalian orthoreoviruses (reoviruses) are nonenveloped double-stranded RNA viruses that infect mos

38 rototype members of the Reoviridae family of nonenveloped double-stranded RNA viruses, use at least t

39 Papillomaviruses are nonenveloped, double-stranded DNA viruses that are assoc

40 BTV is a nonenveloped, double-stranded RNA (dsRNA) virus with two

41 Hepatovirus, existing in both enveloped and nonenveloped forms, and with a capsid structure intermed

42 We found that compared to nonenveloped HEV virions, eHEV attachment to the cell wa

43 Unlike nonenveloped HEV virions, eHEV entry requires Rab5 and R

44 The nonenveloped, hollow, cylindrical virion is formed from

45 icking.IMPORTANCE After internalization, the nonenveloped human papillomavirus virion uncoats in the

46 ersistence of adenovirus type 5, a prevalent nonenveloped human virus, are dependent upon the intrace

47 Circoviruses are small, nonenveloped icosahedral animal viruses characterized by

48 Reovirus virions are nonenveloped icosahedral particles consisting of two con

49 The papillomavirus capsid is a nonenveloped icosahedral shell formed by the viral major

50 Iflaviruses have nonenveloped icosahedral virions containing single-stran

51 nimal viruses, this is the first report of a nonenveloped icosahedral virus CP inhibiting classical p

52 Porcine circovirus 2 (PCV2) is a T=1 nonenveloped icosahedral virus that has had severe impac

53 , of infectious pancreatic necrosis virus, a nonenveloped icosahedral virus, contains six N-glycosyla

54 licing.IMPORTANCE The Parvovirinae are small nonenveloped icosahedral viruses that are important path

55 The Parvovirinae are small nonenveloped icosahedral viruses that are important path

56 jor causes of childhood gastroenteritis, are nonenveloped, icosahedral particles with double-strand R

57 astroviruses (HAstVs) belong to a family of nonenveloped, icosahedral RNA viruses that cause noninfl

58 ncapsidated dsRNA viruses, most of which are nonenveloped, infect a wide variety of hosts, from bacte

59 The outer capsid of the nonenveloped mammalian reovirus contains 200 trimers of

60 Membrane penetration by the nonenveloped mammalian reoviruses is believed to deliver

61 cteriophages as pathogenic virus surrogates: nonenveloped MS2 and Qbeta and enveloped Phi6.

62 5.6% (+/-16.7%) and 85.5% (+/-24.5%) for the nonenveloped MS2 and T3, respectively.

63 Giardia lamblia virus (GLV) is a small, nonenveloped, nonsegmented double-stranded RNA (dsRNA) v

64 Mammalian reoviruses are nonenveloped particles containing a genome of 10 double-

65 other members of the family, BTV virions are nonenveloped particles containing two architecturally co

66 The nonenveloped parvovirus capsid carries determinants of h

67 itis virus, and dengue virus but not for the nonenveloped poliovirus.

68 The nonenveloped polyomavirus (Py) traffics from the plasma

69 The nonenveloped polyomavirus (PyV) simian virus 40 (SV40) t

70 The nonenveloped polyomavirus simian virus 40 (SV40) is take

71 In the case of the nonenveloped polyomavirus simian virus 40 (SV40), the vi

72 ring ER-to-cytosol membrane transport of the nonenveloped polyomavirus SV40, a decisive infection ste

73 d results were compared with those for other nonenveloped positive-stranded viruses (astroviruses and

74 LVs) are a diverse group of single-stranded, nonenveloped, positive-polarity RNA viruses and are the

75 Human astroviruses are nonenveloped, positive-sense single-strand RNA viruses a

76 Astroviruses are nonenveloped, positive-sense single-stranded RNA viruses

77 Human astroviruses (HAstVs) are nonenveloped, positive-sense, single-stranded RNA viruse

78 Parvoviruses are small, rugged, nonenveloped protein particles containing a linear, nonp

79 Classically considered "nonenveloped," recent studies show that some picornaviru

80 Membrane penetration by nonenveloped reoviruses is mediated by the outer-capsid

81 Hepatitis E virus is a nonenveloped RNA virus.

82 We conclude that the genetic content of nonenveloped RNA viruses is variable, not just by genome

83 Noroviruses are a diverse group of nonenveloped RNA viruses that are continuously evolving.

84 For many nonenveloped RNA viruses the requirements for this criti

85 In the picornavirus family of nonenveloped RNA viruses, the requirements for genome pa

86 The nonenveloped, rod-shaped virus SIRV2 (Sulfolobus islandi

87 roteins composing the outermost layer of the nonenveloped RV triple-layered icosahedral particle (TLP

88 The nonenveloped simian polyomavirus (PyV) simian virus 40 (

89 The nonenveloped simian virus 40 (SV40) hijacks the three en

90 Members of the genus Parvovirus are small, nonenveloped single-stranded DNA viruses that are nonpat

91 e investigated the RNA content of a purified nonenveloped single-stranded RNA virus, flock house viru

92 pe member of the Bocaparvovirus genus of the nonenveloped, single-stranded DNA (ssDNA) Parvoviridae f

93 and maturation of the coat protein of a T=4, nonenveloped, single-stranded RNA virus, Nudaurelia cape

94 Astroviruses are small, nonenveloped, single-stranded RNA viruses that cause dia

95 ridae family, which consists of icosahedral, nonenveloped, single-stranded RNA viruses.

96 uced in tissue culture cells by rotavirus, a nonenveloped, triple-protein-layered member of the Reovi

97 BK virus (BKV) is a nonenveloped, ubiquitous human polyomavirus that establi

98 re what appears to be the first example of a nonenveloped viral capsid that appears to have a role in

99 Nonenveloped viral capsids are metastable structures tha

100 ly investigate the innate immune response to nonenveloped viral infection in vivo.

101 Nonenveloped virions accumulate in the cytoplasm of cell

102 ential for assembly of infectious virus, and nonenveloped virions accumulate in the cytoplasm of cell

103 hepatitis E virus (HEV) sheds into feces as nonenveloped virions but circulates in the blood in a me

104 ating dissemination within the host, whereas nonenveloped virions shed in feces are stable in the env

105 e human pathogens are shed in feces as naked nonenveloped virions, recent studies indicate that both

106 ions, although it produces normal amounts of nonenveloped virions.

107 characterized direct interactions of a whole nonenveloped virus (simian virus 40), as well as those o

108 f the ESCRT machinery in the life cycle of a nonenveloped virus and highlights the complex mechanism

109 vidence that IFITM3 restricts infection by a nonenveloped virus and suggest that IFITM3 targets an in

110 ctor that mediates membrane penetration of a nonenveloped virus and suggest that PDI family members a

111 genome of bluetongue virus (BTV), a complex nonenveloped virus belonging to the Reoviridae family.

112 results provide a detailed analysis of how a nonenveloped virus can enter its host cell.

113 ultiple copies of the same protein form many nonenveloped virus capsids, it is unclear if lytic pepti

114 hus providing insight into the regulation of nonenveloped virus disassembly.

115 sults suggest a well-orchestrated process of nonenveloped virus entry involving autocleavage of the p

116 ions for understanding membrane lysis during nonenveloped virus entry.

117 nteraction in which membranes can facilitate nonenveloped virus entry.

118 Although concentrated nonenveloped virus failed to activate freshly isolated h

119 entral helical bundle, observed in different nonenveloped virus families, are a specialized lytic mot

120 viously unrecognized enzymatic mechanism for nonenveloped virus penetration.

121 irst demonstration of a functional ITAM in a nonenveloped virus presents a new mechanism for viral IT

122 icated in the intracellular trafficking of a nonenveloped virus such as HPV.

123 mbrane penetration apparatus of rotavirus, a nonenveloped virus that causes childhood gastroenteritis

124 Canine parvovirus (CPV) is a small, nonenveloped virus that is a host range variant of a vir

125 Adeno-associated virus (AAV) is a small, nonenveloped virus that was adapted 30 years ago for use

126 th membranes can function as a trigger for a nonenveloped virus to gain entry into host cells.

127 link the activity of a cellular factor on a nonenveloped virus to the membrane perforation event and

128 TA in controlling this step.IMPORTANCE How a nonenveloped virus transports across a biological membra

129 HAstV is a nonenveloped virus with a T=3 capsid and a positive-sens

130 As a nonenveloped virus, HAstV exhibits an intriguing feature

131 As a nonenveloped virus, HPV enters cells by interacting with

132 A nonenveloped virus, simian virus 40, was not affected by

133 Despite being a nonenveloped virus, the putative VP5 membrane penetratio

134 ut not by reovirus, a structurally unrelated nonenveloped virus.

135 ed in our understanding of cellular entry by nonenveloped viruses (NEVs).

136 It is likely that other nonenveloped viruses also use this pathway for nonlytic

137 l spread of cytoplasmic constituents such as nonenveloped viruses and aggregated proteins is usually

138 in mammalian cells, including the release of nonenveloped viruses and apoptosis.

139 ategy to modulate the biological function of nonenveloped viruses and may have implications broader t

140 se replicative fitness.IMPORTANCE Capsids of nonenveloped viruses are composed of protein complexes t

141 chanisms involved in membrane penetration by nonenveloped viruses are not as well understood.

142 Nonenveloped viruses are, by their very nature, denied t

143 ese results indicate that capsid proteins of nonenveloped viruses can interact among themselves withi

144 this work illustrates a novel strategy that nonenveloped viruses can use to gain access into cells a

145 The process by which nonenveloped viruses cross cell membranes during host ce

146 l-characterized system for understanding how nonenveloped viruses enter and infect cells.

147 Many nonenveloped viruses have evolved an infectious cycle th

148 In order to complete infectious entry, nonenveloped viruses have to pass cellular membranes.

149 antiviral action for alpha-defensins against nonenveloped viruses in which HD5 directly interferes wi

150 The Picornaviridae family of small, nonenveloped viruses includes major pathogens of humans

151 Membrane penetration of nonenveloped viruses is a poorly understood process.

152 es in the assembly pathways of enveloped and nonenveloped viruses may be far simpler than previously

153 ansmit their genetic material to a new host, nonenveloped viruses must protect their genomes by packa

154 To achieve cell entry, many nonenveloped viruses must transform from a dormant to a

155 Nonenveloped viruses often invade membranes by exposing

156 was stimulated after infection by DNA or RNA nonenveloped viruses or intracellular bacteria.

157 Nonenveloped viruses protect their genomes by packaging

158 Membrane penetration by nonenveloped viruses remains enigmatic.

159 We focus here on small nonenveloped viruses such as adeno-associated viruses, w

160 ons may reflect a general mechanism by which nonenveloped viruses such as poliovirus and other viruse

161 Nonenveloped viruses such as Simian Virus 40 (SV40) expl

162 For nonenveloped viruses such as Simian Virus 40, the mechan

163 , a situation that may be relevant for other nonenveloped viruses that use microtubule-dependent tran

164 ition, we used cNDs to visualize how simple, nonenveloped viruses translocate their genomes across me

165 Some nonenveloped viruses use retrograde trafficking for entr

166 whereas ricin and Shiga-like toxins and some nonenveloped viruses use the retrograde pathway for cell

167 cell entry and infection, many enveloped and nonenveloped viruses utilize cell surface receptors that

168 Recent studies have established that several nonenveloped viruses utilize virus-encoded lytic peptide

169 Mammalian reoviruses are nonenveloped viruses with a long, filamentous attachment

170 Polyomaviruses are nonenveloped viruses with capsids composed primarily of

171 ing to its host cell, poliovirus (like other nonenveloped viruses) faces the challenge of translocati

172 A number of nonenveloped viruses, including AAV, carry proteases tha

173 f membrane penetration for Py, and for other nonenveloped viruses, remains poorly characterized.

174 possible activity of these peptides against nonenveloped viruses, such as HPVs.

175 Reoviruses, a model system for entry of nonenveloped viruses, undergo a series of disassembly st

176 system for studying the entry mechanisms of nonenveloped viruses, undergoes a series of regulated st

177 The enzymes encoded by nonenveloped viruses-a group of viruses that lack any li

178 e compound had no effect on the infection of nonenveloped viruses.

179 ng and internalization of both enveloped and nonenveloped viruses.

180 eptors in the infectious pathways of several nonenveloped viruses.

181 nzymes and autocatalytic activity encoded by nonenveloped viruses.

182 tion of wastewater compared to 6% of the two nonenveloped viruses.

183 lexibility described for other enveloped and nonenveloped viruses.

184 son, less is known about antibody binding to nonenveloped viruses.

185 driven process of antibody neutralization of nonenveloped viruses.

186 ced with capsid proteins from two unrelated, nonenveloped viruses: simian virus 40 and satellite toba